Oral papillary plasmacytosis resembling candidosis without demonstrable fungus in lesional tissue
Identifieur interne : 005D81 ( Istex/Corpus ); précédent : 005D80; suivant : 005D82Oral papillary plasmacytosis resembling candidosis without demonstrable fungus in lesional tissue
Auteurs : C. E. H. Grattan ; T. A. Gentle ; M. K. BasuSource :
- Clinical and Experimental Dermatology [ 0307-6938 ] ; 1992-03.
English descriptors
- KwdEn :
- Albicans, Alhicans, Angular stomatitis, Antifungal, Buccal mucosa, Candida, Candida albicans, Candida alhicans, Candida antigen, Candida infection, Candidosis, Cellular immunity, Chronic candidosis, Clinical improvement, Cutaneous, Cutaneous plasmacytic infiltrates, Denture, Dermatology, Fungal elements, Gingiva, Hard palate, Histology, Hyperplasia, Hypersensitivity reaction, Infiltrates, Inflammatory, Ketoconazole, Lesional tissue, Levamisole, Neutrophil, Nodular, Nodular hyperplasia, Ofthe, Oral mucosa, Oral surgery, Palate, Papillary, Papillary hyperplasia, Plasma cells, Plasmacytosis, Serum iron, Smooth plaques, Soft palate, Stomatitis, Topical antifungals.
- Teeft :
- Albicans, Alhicans, Angular stomatitis, Antifungal, Buccal mucosa, Candida, Candida albicans, Candida alhicans, Candida antigen, Candida infection, Candidosis, Cellular immunity, Chronic candidosis, Clinical improvement, Cutaneous, Cutaneous plasmacytic infiltrates, Denture, Dermatology, Fungal elements, Gingiva, Hard palate, Histology, Hyperplasia, Hypersensitivity reaction, Infiltrates, Inflammatory, Ketoconazole, Lesional tissue, Levamisole, Neutrophil, Nodular, Nodular hyperplasia, Ofthe, Oral mucosa, Oral surgery, Palate, Papillary, Papillary hyperplasia, Plasma cells, Plasmacytosis, Serum iron, Smooth plaques, Soft palate, Stomatitis, Topical antifungals.
Abstract
Two cases with exuberant papillary and nodular hyperplasia of the hard and soft palates are described. Both were elderly edentulous men with bilateral angular stomatitis. The papillary hyperplasia extended as far as the epiglottis and was associated with swelling and fissuring of the upper lip in patient 1. In patient 2, the palatal change extended to the maxillary gingiva and was associated with smooth plaques and fissuring of the dorsal tongue. Histology of both cases showed a dense polyclonal plasma‐cell infiltrate with overlying epithelial hyperplasia, parakeratinization and neutrophil micro‐abscesses suggesting Candida infection but fungal elements could not be demonstrated. Patient 1 also showed defective cellular immunity to Candida antigen which was reversed by treatment with ketoconazole and levamisole, antedating clinical improvement.
Url:
DOI: 10.1111/j.1365-2230.1992.tb00176.x
Links to Exploration step
ISTEX:BC5D03EAD0E584AA976541AE8D4BBD8D31A59ABBLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Oral papillary plasmacytosis resembling candidosis without demonstrable fungus in lesional tissue</title><author><name sortKey="Grattan, C E H" sort="Grattan, C E H" uniqKey="Grattan C" first="C. E. H." last="Grattan">C. E. H. Grattan</name><affiliation><mods:affiliation>Departments of Dermatology, General Hospital</mods:affiliation></affiliation><affiliation><mods:affiliation>Correspondence address: Dr C.E.H. Grattan, Department of Dermatology, Norfolk & Norwich Hospital, Norwich, Norfolk NR1 3SR, UK.</mods:affiliation></affiliation></author><author><name sortKey="Gentle, T A" sort="Gentle, T A" uniqKey="Gentle T" first="T. A." last="Gentle">T. A. Gentle</name><affiliation><mods:affiliation>Immunology, East Birmingham Hospital</mods:affiliation></affiliation></author><author><name sortKey="Basu, M K" sort="Basu, M K" uniqKey="Basu M" first="M. K." last="Basu">M. K. Basu</name><affiliation><mods:affiliation>Oral Pathology, Dental Hospital, Birmingham, UK</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:BC5D03EAD0E584AA976541AE8D4BBD8D31A59ABB</idno><date when="1992" year="1992">1992</date><idno type="doi">10.1111/j.1365-2230.1992.tb00176.x</idno><idno type="url">https://api.istex.fr/document/BC5D03EAD0E584AA976541AE8D4BBD8D31A59ABB/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">005D81</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">005D81</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Oral papillary plasmacytosis resembling candidosis without demonstrable fungus in lesional tissue</title><author><name sortKey="Grattan, C E H" sort="Grattan, C E H" uniqKey="Grattan C" first="C. E. H." last="Grattan">C. E. H. Grattan</name><affiliation><mods:affiliation>Departments of Dermatology, General Hospital</mods:affiliation></affiliation><affiliation><mods:affiliation>Correspondence address: Dr C.E.H. Grattan, Department of Dermatology, Norfolk & Norwich Hospital, Norwich, Norfolk NR1 3SR, UK.</mods:affiliation></affiliation></author><author><name sortKey="Gentle, T A" sort="Gentle, T A" uniqKey="Gentle T" first="T. A." last="Gentle">T. A. Gentle</name><affiliation><mods:affiliation>Immunology, East Birmingham Hospital</mods:affiliation></affiliation></author><author><name sortKey="Basu, M K" sort="Basu, M K" uniqKey="Basu M" first="M. K." last="Basu">M. K. Basu</name><affiliation><mods:affiliation>Oral Pathology, Dental Hospital, Birmingham, UK</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Clinical and Experimental Dermatology</title><title level="j" type="alt">CLINICAL EXPERIMENTAL DERMATOLOGY</title><idno type="ISSN">0307-6938</idno><idno type="eISSN">1365-2230</idno><imprint><biblScope unit="vol">17</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="112">112</biblScope><biblScope unit="page" to="116">116</biblScope><biblScope unit="page-count">5</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="1992-03">1992-03</date></imprint><idno type="ISSN">0307-6938</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0307-6938</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Albicans</term><term>Alhicans</term><term>Angular stomatitis</term><term>Antifungal</term><term>Buccal mucosa</term><term>Candida</term><term>Candida albicans</term><term>Candida alhicans</term><term>Candida antigen</term><term>Candida infection</term><term>Candidosis</term><term>Cellular immunity</term><term>Chronic candidosis</term><term>Clinical improvement</term><term>Cutaneous</term><term>Cutaneous plasmacytic infiltrates</term><term>Denture</term><term>Dermatology</term><term>Fungal elements</term><term>Gingiva</term><term>Hard palate</term><term>Histology</term><term>Hyperplasia</term><term>Hypersensitivity reaction</term><term>Infiltrates</term><term>Inflammatory</term><term>Ketoconazole</term><term>Lesional tissue</term><term>Levamisole</term><term>Neutrophil</term><term>Nodular</term><term>Nodular hyperplasia</term><term>Ofthe</term><term>Oral mucosa</term><term>Oral surgery</term><term>Palate</term><term>Papillary</term><term>Papillary hyperplasia</term><term>Plasma cells</term><term>Plasmacytosis</term><term>Serum iron</term><term>Smooth plaques</term><term>Soft palate</term><term>Stomatitis</term><term>Topical antifungals</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Albicans</term><term>Alhicans</term><term>Angular stomatitis</term><term>Antifungal</term><term>Buccal mucosa</term><term>Candida</term><term>Candida albicans</term><term>Candida alhicans</term><term>Candida antigen</term><term>Candida infection</term><term>Candidosis</term><term>Cellular immunity</term><term>Chronic candidosis</term><term>Clinical improvement</term><term>Cutaneous</term><term>Cutaneous plasmacytic infiltrates</term><term>Denture</term><term>Dermatology</term><term>Fungal elements</term><term>Gingiva</term><term>Hard palate</term><term>Histology</term><term>Hyperplasia</term><term>Hypersensitivity reaction</term><term>Infiltrates</term><term>Inflammatory</term><term>Ketoconazole</term><term>Lesional tissue</term><term>Levamisole</term><term>Neutrophil</term><term>Nodular</term><term>Nodular hyperplasia</term><term>Ofthe</term><term>Oral mucosa</term><term>Oral surgery</term><term>Palate</term><term>Papillary</term><term>Papillary hyperplasia</term><term>Plasma cells</term><term>Plasmacytosis</term><term>Serum iron</term><term>Smooth plaques</term><term>Soft palate</term><term>Stomatitis</term><term>Topical antifungals</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Two cases with exuberant papillary and nodular hyperplasia of the hard and soft palates are described. Both were elderly edentulous men with bilateral angular stomatitis. The papillary hyperplasia extended as far as the epiglottis and was associated with swelling and fissuring of the upper lip in patient 1. In patient 2, the palatal change extended to the maxillary gingiva and was associated with smooth plaques and fissuring of the dorsal tongue. Histology of both cases showed a dense polyclonal plasma‐cell infiltrate with overlying epithelial hyperplasia, parakeratinization and neutrophil micro‐abscesses suggesting Candida infection but fungal elements could not be demonstrated. Patient 1 also showed defective cellular immunity to Candida antigen which was reversed by treatment with ketoconazole and levamisole, antedating clinical improvement.</div></front></TEI><istex><corpusName>wiley</corpusName><keywords><teeft><json:string>candida</json:string><json:string>levamisole</json:string><json:string>plasmacytosis</json:string><json:string>neutrophil</json:string><json:string>hyperplasia</json:string><json:string>gingiva</json:string><json:string>ofthe</json:string><json:string>ketoconazole</json:string><json:string>antifungal</json:string><json:string>plasma cells</json:string><json:string>alhicans</json:string><json:string>stomatitis</json:string><json:string>palate</json:string><json:string>dermatology</json:string><json:string>denture</json:string><json:string>infiltrates</json:string><json:string>candida infection</json:string><json:string>cutaneous</json:string><json:string>soft palate</json:string><json:string>candida albicans</json:string><json:string>candidosis</json:string><json:string>inflammatory</json:string><json:string>papillary</json:string><json:string>candida alhicans</json:string><json:string>topical antifungals</json:string><json:string>albicans</json:string><json:string>nodular</json:string><json:string>lesional tissue</json:string><json:string>papillary hyperplasia</json:string><json:string>smooth plaques</json:string><json:string>clinical improvement</json:string><json:string>serum iron</json:string><json:string>chronic candidosis</json:string><json:string>cellular immunity</json:string><json:string>hard palate</json:string><json:string>nodular hyperplasia</json:string><json:string>candida antigen</json:string><json:string>angular stomatitis</json:string><json:string>oral surgery</json:string><json:string>cutaneous plasmacytic infiltrates</json:string><json:string>buccal mucosa</json:string><json:string>hypersensitivity reaction</json:string><json:string>oral mucosa</json:string><json:string>fungal elements</json:string><json:string>histology</json:string></teeft></keywords><author><json:item><name>C.E.H. GRATTAN</name><affiliations><json:string>Departments of Dermatology, General Hospital</json:string><json:string>Correspondence address: Dr C.E.H. Grattan, Department of Dermatology, Norfolk & Norwich Hospital, Norwich, Norfolk NR1 3SR, UK.</json:string></affiliations></json:item><json:item><name>T.A. GENTLE</name><affiliations><json:string>Immunology, East Birmingham Hospital</json:string></affiliations></json:item><json:item><name>M.K. BASU</name><affiliations><json:string>Oral Pathology, Dental Hospital, Birmingham, UK</json:string></affiliations></json:item></author><articleId><json:string>CED112</json:string></articleId><arkIstex>ark:/67375/WNG-TL93GVQN-D</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>Two cases with exuberant papillary and nodular hyperplasia of the hard and soft palates are described. Both were elderly edentulous men with bilateral angular stomatitis. The papillary hyperplasia extended as far as the epiglottis and was associated with swelling and fissuring of the upper lip in patient 1. In patient 2, the palatal change extended to the maxillary gingiva and was associated with smooth plaques and fissuring of the dorsal tongue. Histology of both cases showed a dense polyclonal plasma‐cell infiltrate with overlying epithelial hyperplasia, parakeratinization and neutrophil micro‐abscesses suggesting Candida infection but fungal elements could not be demonstrated. Patient 1 also showed defective cellular immunity to Candida antigen which was reversed by treatment with ketoconazole and levamisole, antedating clinical improvement.</abstract><qualityIndicators><score>5.449</score><pdfWordCount>1997</pdfWordCount><pdfCharCount>13177</pdfCharCount><pdfVersion>1.4</pdfVersion><pdfPageCount>6</pdfPageCount><pdfPageSize>554 x 723 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractWordCount>121</abstractWordCount><abstractCharCount>856</abstractCharCount><keywordCount>0</keywordCount></qualityIndicators><title>Oral papillary plasmacytosis resembling candidosis without demonstrable fungus in lesional tissue</title><pmid><json:string>1516234</json:string></pmid><genre><json:string>article</json:string></genre><host><title>Clinical and Experimental Dermatology</title><language><json:string>unknown</json:string></language><doi><json:string>10.1111/(ISSN)1365-2230</json:string></doi><issn><json:string>0307-6938</json:string></issn><eissn><json:string>1365-2230</json:string></eissn><publisherId><json:string>CED</json:string></publisherId><volume>17</volume><issue>2</issue><pages><first>112</first><last>116</last><total>5</total></pages><genre><json:string>journal</json:string></genre></host><namedEntities><unitex><date><json:string>1974</json:string><json:string>1992</json:string><json:string>1979</json:string><json:string>1986</json:string><json:string>1988</json:string><json:string>1973</json:string><json:string>1940</json:string><json:string>1985</json:string></date><geogName></geogName><orgName><json:string>Department of Dermatology</json:string><json:string>Norwich Hospital, Norwich, Norfolk</json:string><json:string>International Contact Dermatitis Research Group</json:string></orgName><orgName_funder></orgName_funder><orgName_provider></orgName_provider><persName><json:string>Lymphoeyte</json:string><json:string>Xray</json:string><json:string>C.E.H.Grattan</json:string><json:string>Control</json:string><json:string>Torres</json:string><json:string>Examination</json:string></persName><placeName><json:string>UK</json:string><json:string>Norfolk</json:string><json:string>Kosin</json:string></placeName><ref_url></ref_url><ref_bibl></ref_bibl><bibl></bibl></unitex></namedEntities><ark><json:string>ark:/67375/WNG-TL93GVQN-D</json:string></ark><categories><wos><json:string>1 - science</json:string><json:string>2 - dermatology</json:string></wos><scienceMetrix><json:string>1 - health sciences</json:string><json:string>2 - clinical medicine</json:string><json:string>3 - dermatology & venereal diseases</json:string></scienceMetrix><scopus><json:string>1 - Health Sciences</json:string><json:string>2 - Medicine</json:string><json:string>3 - Dermatology</json:string></scopus><inist><json:string>1 - sciences appliquees, technologies et medecines</json:string><json:string>2 - sciences biologiques et medicales</json:string><json:string>3 - sciences medicales</json:string><json:string>4 - hemopathies</json:string></inist></categories><publicationDate>1992</publicationDate><copyrightDate>1992</copyrightDate><doi><json:string>10.1111/j.1365-2230.1992.tb00176.x</json:string></doi><id>BC5D03EAD0E584AA976541AE8D4BBD8D31A59ABB</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/BC5D03EAD0E584AA976541AE8D4BBD8D31A59ABB/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/BC5D03EAD0E584AA976541AE8D4BBD8D31A59ABB/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/BC5D03EAD0E584AA976541AE8D4BBD8D31A59ABB/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main">Oral papillary plasmacytosis resembling candidosis without demonstrable fungus in lesional tissue</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="1992-03"></date></publicationStmt><notesStmt><note type="content-type" subtype="article" source="article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="article"><analytic><title level="a" type="main">Oral papillary plasmacytosis resembling candidosis without demonstrable fungus in lesional tissue</title><author xml:id="author-0000" role="corresp"><persName><forename type="first">C.E.H.</forename><surname>GRATTAN</surname></persName><affiliation>Departments of Dermatology, General Hospital</affiliation><affiliation>Dr C.E.H. Grattan, Department of Dermatology, Norfolk & Norwich Hospital, Norwich, Norfolk NR1 3SR, UK.</affiliation></author><author xml:id="author-0001"><persName><forename type="first">T.A.</forename><surname>GENTLE</surname></persName><affiliation>Immunology, East Birmingham Hospital</affiliation></author><author xml:id="author-0002"><persName><forename type="first">M.K.</forename><surname>BASU</surname></persName><affiliation>Oral Pathology, Dental Hospital, Birmingham, UK<address><country key="GB"></country></address></affiliation></author><idno type="istex">BC5D03EAD0E584AA976541AE8D4BBD8D31A59ABB</idno><idno type="ark">ark:/67375/WNG-TL93GVQN-D</idno><idno type="DOI">10.1111/j.1365-2230.1992.tb00176.x</idno><idno type="unit">CED112</idno><idno type="toTypesetVersion">file:CED.CED112.pdf</idno></analytic><monogr><title level="j" type="main">Clinical and Experimental Dermatology</title><title level="j" type="alt">CLINICAL EXPERIMENTAL DERMATOLOGY</title><idno type="pISSN">0307-6938</idno><idno type="eISSN">1365-2230</idno><idno type="book-DOI">10.1111/(ISSN)1365-2230</idno><idno type="book-part-DOI">10.1111/ced.1992.17.issue-2</idno><idno type="product">CED</idno><idno type="publisherDivision">ST</idno><imprint><biblScope unit="vol">17</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="112">112</biblScope><biblScope unit="page" to="116">116</biblScope><biblScope unit="page-count">5</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="1992-03"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><abstract xml:lang="en" style="main"><head>Summary</head><p>Two cases with exuberant papillary and nodular hyperplasia of the hard and soft palates are described. Both were elderly edentulous men with bilateral angular stomatitis. The papillary hyperplasia extended as far as the epiglottis and was associated with swelling and fissuring of the upper lip in patient 1. In patient 2, the palatal change extended to the maxillary gingiva and was associated with smooth plaques and fissuring of the dorsal tongue. Histology of both cases showed a dense polyclonal plasma‐cell infiltrate with overlying epithelial hyperplasia, parakeratinization and neutrophil micro‐abscesses suggesting <hi rend="italic">Candida</hi> infection but fungal elements could not be demonstrated. Patient 1 also showed defective cellular immunity to <hi rend="italic">Candida</hi> antigen which was reversed by treatment with ketoconazole and levamisole, antedating clinical improvement.</p></abstract><textClass><keywords rend="tocHeading1"><term>Original Articles</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/BC5D03EAD0E584AA976541AE8D4BBD8D31A59ABB/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Publishing Ltd</publisherName><publisherLoc>Oxford, UK</publisherLoc></publisherInfo><doi origin="wiley" registered="yes">10.1111/(ISSN)1365-2230</doi><issn type="print">0307-6938</issn><issn type="electronic">1365-2230</issn><idGroup><id type="product" value="CED"></id><id type="publisherDivision" value="ST"></id></idGroup><titleGroup><title type="main" sort="CLINICAL EXPERIMENTAL DERMATOLOGY">Clinical and Experimental Dermatology</title></titleGroup></publicationMeta><publicationMeta level="part" position="03002"><doi origin="wiley">10.1111/ced.1992.17.issue-2</doi><numberingGroup><numbering type="journalVolume" number="17">17</numbering><numbering type="journalIssue" number="2">2</numbering></numberingGroup><coverDate startDate="1992-03">March 1992</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="0011200" status="forIssue"><doi origin="wiley">10.1111/j.1365-2230.1992.tb00176.x</doi><idGroup><id type="unit" value="CED112"></id></idGroup><countGroup><count type="pageTotal" number="5"></count></countGroup><titleGroup><title type="tocHeading1">Original Articles</title></titleGroup><eventGroup><event type="firstOnline" date="2006-04-27"></event><event type="publishedOnlineFinalForm" date="2006-04-27"></event><event type="xmlConverted" agent="Converter:BPG_TO_WML3G version:2.3.2 mode:FullText source:HeaderRef result:HeaderRef" date="2010-03-09"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-09"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-16"></event></eventGroup><numberingGroup><numbering type="pageFirst" number="112">112</numbering><numbering type="pageLast" number="116">116</numbering></numberingGroup><correspondenceTo>Dr C.E.H. Grattan, Department of Dermatology, Norfolk & Norwich Hospital, Norwich, Norfolk NR1 3SR, UK.</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:CED.CED112.pdf"></link></linkGroup></publicationMeta><contentMeta><unparsedEditorialHistory>Accepted for publication 28 February 1991</unparsedEditorialHistory><countGroup><count type="referenceTotal" number="10"></count><count type="linksCrossRef" number="4"></count></countGroup><titleGroup><title type="main">Oral papillary plasmacytosis resembling candidosis without demonstrable fungus in lesional tissue</title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#a1" corresponding="yes"><personName><givenNames>C.E.H.</givenNames><familyName>GRATTAN</familyName></personName></creator><creator creatorRole="author" xml:id="cr2" affiliationRef="#a2"><personName><givenNames>T.A.</givenNames><familyName>GENTLE</familyName></personName></creator><creator creatorRole="author" xml:id="cr3" affiliationRef="#a3"><personName><givenNames>M.K.</givenNames><familyName>BASU</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="a1"><unparsedAffiliation>Departments of Dermatology, General Hospital</unparsedAffiliation></affiliation><affiliation xml:id="a2"><unparsedAffiliation>Immunology, East Birmingham Hospital</unparsedAffiliation></affiliation><affiliation xml:id="a3" countryCode="GB"><unparsedAffiliation>Oral Pathology, Dental Hospital, Birmingham, UK</unparsedAffiliation></affiliation></affiliationGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Summary</title><p>Two cases with exuberant papillary and nodular hyperplasia of the hard and soft palates are described. Both were elderly edentulous men with bilateral angular stomatitis. The papillary hyperplasia extended as far as the epiglottis and was associated with swelling and fissuring of the upper lip in patient 1. In patient 2, the palatal change extended to the maxillary gingiva and was associated with smooth plaques and fissuring of the dorsal tongue. Histology of both cases showed a dense polyclonal plasma‐cell infiltrate with overlying epithelial hyperplasia, parakeratinization and neutrophil micro‐abscesses suggesting <i>Candida</i> infection but fungal elements could not be demonstrated. Patient 1 also showed defective cellular immunity to <i>Candida</i> antigen which was reversed by treatment with ketoconazole and levamisole, antedating clinical improvement.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Oral papillary plasmacytosis resembling candidosis without demonstrable fungus in lesional tissue</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Oral papillary plasmacytosis resembling candidosis without demonstrable fungus in lesional tissue</title></titleInfo><name type="personal"><namePart type="given">C.E.H.</namePart><namePart type="family">GRATTAN</namePart><affiliation>Departments of Dermatology, General Hospital</affiliation><affiliation>Correspondence address: Dr C.E.H. Grattan, Department of Dermatology, Norfolk & Norwich Hospital, Norwich, Norfolk NR1 3SR, UK.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T.A.</namePart><namePart type="family">GENTLE</namePart><affiliation>Immunology, East Birmingham Hospital</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.K.</namePart><namePart type="family">BASU</namePart><affiliation>Oral Pathology, Dental Hospital, Birmingham, UK</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">1992-03</dateIssued><edition>Accepted for publication 28 February 1991</edition><copyrightDate encoding="w3cdtf">1992</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="references">10</extent><extent unit="linksCrossRef">4</extent></physicalDescription><abstract lang="en">Two cases with exuberant papillary and nodular hyperplasia of the hard and soft palates are described. Both were elderly edentulous men with bilateral angular stomatitis. The papillary hyperplasia extended as far as the epiglottis and was associated with swelling and fissuring of the upper lip in patient 1. In patient 2, the palatal change extended to the maxillary gingiva and was associated with smooth plaques and fissuring of the dorsal tongue. Histology of both cases showed a dense polyclonal plasma‐cell infiltrate with overlying epithelial hyperplasia, parakeratinization and neutrophil micro‐abscesses suggesting Candida infection but fungal elements could not be demonstrated. Patient 1 also showed defective cellular immunity to Candida antigen which was reversed by treatment with ketoconazole and levamisole, antedating clinical improvement.</abstract><relatedItem type="host"><titleInfo><title>Clinical and Experimental Dermatology</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><identifier type="ISSN">0307-6938</identifier><identifier type="eISSN">1365-2230</identifier><identifier type="DOI">10.1111/(ISSN)1365-2230</identifier><identifier type="PublisherID">CED</identifier><part><date>1992</date><detail type="volume"><caption>vol.</caption><number>17</number></detail><detail type="issue"><caption>no.</caption><number>2</number></detail><extent unit="pages"><start>112</start><end>116</end><total>5</total></extent></part></relatedItem><identifier type="istex">BC5D03EAD0E584AA976541AE8D4BBD8D31A59ABB</identifier><identifier type="ark">ark:/67375/WNG-TL93GVQN-D</identifier><identifier type="DOI">10.1111/j.1365-2230.1992.tb00176.x</identifier><identifier type="ArticleID">CED112</identifier><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-L0C46X92-X">wiley</recordContentSource><recordOrigin>Blackwell Publishing Ltd</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/document/BC5D03EAD0E584AA976541AE8D4BBD8D31A59ABB/metadata/json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005D81 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 005D81 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= EdenteV2
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:BC5D03EAD0E584AA976541AE8D4BBD8D31A59ABB
|texte= Oral papillary plasmacytosis resembling candidosis without demonstrable fungus in lesional tissue
}}
| This area was generated with Dilib version V0.6.32. |  |