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Membranes over the lateral window in sinus augmentation procedures: a two‐arm and split‐mouth randomized clinical trials

Identifieur interne : 005B70 ( Istex/Corpus ); précédent : 005B69; suivant : 005B71

Membranes over the lateral window in sinus augmentation procedures: a two‐arm and split‐mouth randomized clinical trials

Auteurs : Jesús Torres García-Denche ; Xixi Wu ; Pedro-Pablo Martinez ; Hazem Eimar ; Daher Jalil-Abumalham Ikbal ; Gonzalo Hernández ; Enrique L Pez-Cabarcos ; Isabel Fernandez-Tresguerres ; Faleh Tamimi

Source :

RBID : ISTEX:B8079DB1095561C293081F8972FABD871CBDDCD7

English descriptors

Abstract

This study evaluates whether or not, among other factors, membrane‐coverage of antrostomy defects improves implant survival in sinus augmentation procedures.

Url:
DOI: 10.1111/jcpe.12153

Links to Exploration step

ISTEX:B8079DB1095561C293081F8972FABD871CBDDCD7

Le document en format XML

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Objective
<p>This study evaluates whether or not, among other factors, membrane‐coverage of antrostomy defects improves implant survival in sinus augmentation procedures.</p>
Materials and Methods
<p>We performed a two‐arm and split‐mouth randomized controlled clinical trial on 104 and 5 patients respectively. In the two‐arm study, antrostomy defects were membrane‐covered in 66 procedures and uncovered in 69, before placing a total of 265 implants that were followed up for 1 year. In the split‐mouth study, following bilateral sinus augmentation, antrostomy defects were membrane‐covered on one side and left uncovered on the contra‐lateral. Bone biopsies from each sinus were histologically analysed 6 months later.</p>
Results
<p>In the two‐arm study, implant survival rates were similar (
<hi rend="italic">p</hi>
 = 0.08) in the membrane‐covered (96.1%) and uncovered (94.2%) groups. In the split‐mouth study, bone augmentation was similar in both groups (
<hi rend="italic">p</hi>
 = 0.52). Delayed implant placement (
<hi rend="italic">p</hi>
 = 0.04), thick Schneider's membrane (≥2 mm) (
<hi rend="italic">p</hi>
 < 0.01), treatment for hypertension (
<hi rend="italic">p</hi>
 = 0.04) and non‐smoking (
<hi rend="italic">p</hi>
 = 0.01) seemed to be associated with lower risk of implant failure.</p>
Conclusions
<p>Implant survival in sinus lifting procedures could be influenced significantly by timing of implant placement, Schneider's membrane thickness, antihypertensive treatment and smoking habits, but not by antrostomy membrane coverage.</p>
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<articleTitle>Membranes over the lateral window in sinus augmentation procedures: a two‐arm and split‐mouth randomized clinical trials</articleTitle>
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<journalTitle>J Clin Periodontol</journalTitle>
<pubYear year="2013">2013</pubYear>
;
<vol>40</vol>
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<pageFirst>1043</pageFirst>
<pageLast>1051</pageLast>
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<title type="main">Membranes over the lateral window in sinus augmentation procedures: a two‐arm and split‐mouth randomized clinical trials</title>
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<i>Torres García‐Denche et al</i>
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<creator affiliationRef="#jcpe12153-aff-0001 #jcpe12153-aff-0002" corresponding="yes" creatorRole="author" xml:id="jcpe12153-cr-0001">
<personName>
<givenNames>Jesús</givenNames>
<familyName>Torres García‐Denche</familyName>
</personName>
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<personName>
<givenNames>Xixi</givenNames>
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<personName>
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<personName>
<givenNames>Hazem</givenNames>
<familyName>Eimar</familyName>
</personName>
</creator>
<creator affiliationRef="#jcpe12153-aff-0002" creatorRole="author" xml:id="jcpe12153-cr-0005">
<personName>
<givenNames>Daher Jalil‐Abumalham</givenNames>
<familyName>Ikbal</familyName>
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<personName>
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<personName>
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<personName>
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<affiliation countryCode="ES" type="organization" xml:id="jcpe12153-aff-0002">
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<orgName>McGill University</orgName>
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<country>Spain</country>
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<keyword xml:id="jcpe12153-kwd-0001">barrier membranes</keyword>
<keyword xml:id="jcpe12153-kwd-0002">bone regeneration</keyword>
<keyword xml:id="jcpe12153-kwd-0003">dental implants</keyword>
<keyword xml:id="jcpe12153-kwd-0004">risk factors</keyword>
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<caption>
<p>
<b>Figure S1.</b>
Stratification grafting technique to ensure 3D filling of the sinus cavity.</p>
<p>
<b>Figure S2.</b>
Meticulous packed of the graft is needed to obtain the graft barrier.</p>
<p>
<b>Figure S3.</b>
Sinus based flow diagram of participants.</p>
<p>
<b>Figure S4.</b>
Patients based flow diagram of participant.</p>
<p>
<b>Figure S5.</b>
Absence of membrane coverage of buccal plate of the maxilla after filling the cavity provoked in some patients a residual space filled with connective tissue (white arrows) and partial loss of bone graft (*). However, we did not observe an excessive graft loss that may compromise implant placement at second stage surgery in any patient.</p>
<p>
<b>Table S1.</b>
Analysis for sinus covered or uncovered depending on the systemic and anatomical conditions (sinus based statistics).</p>
<p>
<b>Table S2.</b>
Effect of implant diameters and lengths on implant survival rate.</p>
<p>
<b>Table S3.</b>
Comparison of numbers for covered and uncovered groups in terms of implant types and corresponding survival rates.</p>
<p>
<b>Table S4.</b>
Information of articles in Pjetursson's review.</p>
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<p>This study evaluates whether or not, among other factors, membrane‐coverage of antrostomy defects improves implant survival in sinus augmentation procedures.</p>
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<title type="main">Materials and Methods</title>
<p>We performed a two‐arm and split‐mouth randomized controlled clinical trial on 104 and 5 patients respectively. In the two‐arm study, antrostomy defects were membrane‐covered in 66 procedures and uncovered in 69, before placing a total of 265 implants that were followed up for 1 year. In the split‐mouth study, following bilateral sinus augmentation, antrostomy defects were membrane‐covered on one side and left uncovered on the contra‐lateral. Bone biopsies from each sinus were histologically analysed 6 months later.</p>
</section>
<section xml:id="jcpe12153-sec-0003">
<title type="main">Results</title>
<p>In the two‐arm study, implant survival rates were similar (
<i>p</i>
 = 0.08) in the membrane‐covered (96.1%) and uncovered (94.2%) groups. In the split‐mouth study, bone augmentation was similar in both groups (
<i>p</i>
 = 0.52). Delayed implant placement (
<i>p</i>
 = 0.04), thick Schneider's membrane (≥2 mm) (
<i>p</i>
 < 0.01), treatment for hypertension (
<i>p</i>
 = 0.04) and non‐smoking (
<i>p</i>
 = 0.01) seemed to be associated with lower risk of implant failure.</p>
</section>
<section xml:id="jcpe12153-sec-0004">
<title type="main">Conclusions</title>
<p>Implant survival in sinus lifting procedures could be influenced significantly by timing of implant placement, Schneider's membrane thickness, antihypertensive treatment and smoking habits, but not by antrostomy membrane coverage.</p>
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<b>Conflict of interest and source of funding statement</b>
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<p>This work was supported by the Ministry of Science and Technology (MAT2006‐13646‐C03‐01), China Scholarship Council, Clifford Wong Fellowship, Canadian Institutes of Health Research (CIHR), Institute of Musculoskeletal Health and Arthritis (IMHA) Bridge Funding, and Le Réseau de recherche en santé buccodentaire et osseuse (RSBO). The authors declare that they have no conflict of interests</p>
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<abstract>We performed a two‐arm and split‐mouth randomized controlled clinical trial on 104 and 5 patients respectively. In the two‐arm study, antrostomy defects were membrane‐covered in 66 procedures and uncovered in 69, before placing a total of 265 implants that were followed up for 1 year. In the split‐mouth study, following bilateral sinus augmentation, antrostomy defects were membrane‐covered on one side and left uncovered on the contra‐lateral. Bone biopsies from each sinus were histologically analysed 6 months later.</abstract>
<abstract>In the two‐arm study, implant survival rates were similar (p = 0.08) in the membrane‐covered (96.1%) and uncovered (94.2%) groups. In the split‐mouth study, bone augmentation was similar in both groups (p = 0.52). Delayed implant placement (p = 0.04), thick Schneider's membrane (≥2 mm) (p < 0.01), treatment for hypertension (p = 0.04) and non‐smoking (p = 0.01) seemed to be associated with lower risk of implant failure.</abstract>
<abstract>Implant survival in sinus lifting procedures could be influenced significantly by timing of implant placement, Schneider's membrane thickness, antihypertensive treatment and smoking habits, but not by antrostomy membrane coverage.</abstract>
<note type="additional physical form">Figure S1. Stratification grafting technique to ensure 3D filling of the sinus cavity. Figure S2. Meticulous packed of the graft is needed to obtain the graft barrier. Figure S3. Sinus based flow diagram of participants. Figure S4. Patients based flow diagram of participant. Figure S5. Absence of membrane coverage of buccal plate of the maxilla after filling the cavity provoked in some patients a residual space filled with connective tissue (white arrows) and partial loss of bone graft (*). However, we did not observe an excessive graft loss that may compromise implant placement at second stage surgery in any patient. Table S1. Analysis for sinus covered or uncovered depending on the systemic and anatomical conditions (sinus based statistics). Table S2. Effect of implant diameters and lengths on implant survival rate. Table S3. Comparison of numbers for covered and uncovered groups in terms of implant types and corresponding survival rates. Table S4. Information of articles in Pjetursson's review.</note>
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