EdenteV2, Istex, Corpus, bibRecord, 005B17

Clinical evaluation of a new collagen matrix (Mucograft® prototype) to enhance the width of keratinized tissue in patients with fixed prosthetic restorations: a randomized prospective clinical trial

Identifieur interne : 005B17 ( Istex/Corpus ); précédent : 005B16; suivant : 005B18

Clinical evaluation of a new collagen matrix (Mucograft® prototype) to enhance the width of keratinized tissue in patients with fixed prosthetic restorations: a randomized prospective clinical trial

Auteurs : Mariano Sanz ; Ram N Lorenzo ; Juan J. Aranda ; Conchita Martin ; Marco Orsini

Source :

Journal of Clinical Periodontology [ 0303-6979 ] ; 2009-10.

RBID : ISTEX:B6FB44C21F53040E02F8B4F1EA9F7EAACBFA16F9

English descriptors

Abstract

Aim: The aim of this study was to test a new collagen matrix (CM) aimed to increase keratinized gingiva/mucosa when compared with the free connective tissue graft (CTG).

Url:

https://api.istex.fr/document/B6FB44C21F53040E02F8B4F1EA9F7EAACBFA16F9/fulltext/pdf

DOI: 10.1111/j.1600-051X.2009.01460.x

Links to Exploration step

ISTEX:B6FB44C21F53040E02F8B4F1EA9F7EAACBFA16F9

Le document en format XML

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<idno type="eISSN">1600-051X</idno>
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<profileDesc><abstract xml:lang="en" style="main"><head>Abstract</head>
<p><hi rend="bold">Aim: </hi>
 The aim of this study was to test a new collagen matrix (CM) aimed to increase keratinized gingiva/mucosa when compared with the free connective tissue graft (CTG).</p>
<p><hi rend="bold">Material and Methods: </hi>
 This randomized longitudinal parallel controlled clinical trial studied 20 patients with at least one location with minimal keratinized tissue (<graphic url="les.gif" rend="leqslant R: less-than-or-eq, slant"></graphic>
1 mm).</p>
<p><hi rend="bold">Main Outcome Measure: </hi>
 The 6‐month width of keratinized tissue. As secondary outcomes, the aesthetic outlook, the maintenance of periodontal health and the patient morbidity were assessed pre‐operatively at 1, 3 and 6 months.</p>
<p><hi rend="bold">Results: </hi>
 At 6 months, the CTG attained a mean width of keratinized tissue of 2.6 (0.9) mm, while the CM was 2.5 (0.9) mm, these differences being insignificant. In both groups, there was a marked contraction (60% and 67%, respectively) although the periodontal parameters were not affected. The CM group had a significantly lower patient morbidity (pain and medication intake) as well as reduced surgery time.</p>
<p><hi rend="bold">Conclusions: </hi>
 These results prove that this new CM was as effective and predictable as the CTG for attaining a band of keratinized tissue, but its use was associated with a significantly lower patient morbidity.</p>
</abstract>
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<keywords rend="tocHeading1"><term>Periodontal Therapy</term>
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<publicationMeta level="unit" type="article" position="8" status="forIssue"><doi origin="wiley">10.1111/j.1600-051X.2009.01460.x</doi>
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<titleGroup><title type="tocHeading1">Periodontal Therapy</title>
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<copyright>© 2009 John Wiley & Sons A/S</copyright>
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<correspondenceTo>Address: <i>Mariano Sanz</i>
<i>Facultad de Odontología</i>
 <i>Universidad Complutense de Madrid</i>
 <i>Plaza Ramón y Cajal</i>
 <i>28040 Madrid</i>
 <i>Spain</i>
 E‐mail: <email normalForm="marianosanz@odon.ucm.es">marianosanz@odon.ucm.es</email>
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<contentMeta><unparsedEditorialHistory>Accepted for publication 22 June 2009</unparsedEditorialHistory>
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<titleGroup><title type="main">Clinical evaluation of a new <i>collagen matrix</i>
 (Mucograft<sup>®</sup>
 prototype) to enhance the width of keratinized tissue in patients with fixed prosthetic restorations: a randomized prospective clinical trial</title>
<title type="shortAuthors">Sanz et al.</title>
<title type="short">A collagen matrix to enhance keratinized tissue around restorations</title>
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<creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#a1"><personName><givenNames>Mariano</givenNames>
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<creator creatorRole="author" xml:id="cr2" affiliationRef="#a1"><personName><givenNames>Ramón</givenNames>
<familyName>Lorenzo</familyName>
</personName>
</creator>
<creator creatorRole="author" xml:id="cr3" affiliationRef="#a1"><personName><givenNames>Juan J.</givenNames>
<familyName>Aranda</familyName>
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</creator>
<creator creatorRole="author" xml:id="cr4" affiliationRef="#a1"><personName><givenNames>Conchita</givenNames>
<familyName>Martin</familyName>
</personName>
</creator>
<creator creatorRole="author" xml:id="cr5" affiliationRef="#a1"><personName><givenNames>Marco</givenNames>
<familyName>Orsini</familyName>
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<affiliationGroup><affiliation xml:id="a1" countryCode="ES"><unparsedAffiliation>Section of Periodontology, Faculty of Odontology, University Complutense of Madrid, Madrid, Spain</unparsedAffiliation>
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<keywordGroup xml:lang="en"><keyword xml:id="k1">aesthetics</keyword>
<keyword xml:id="k2">collagen</keyword>
<keyword xml:id="k3">connective tissue graft</keyword>
<keyword xml:id="k4">keratinized tissue</keyword>
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<supportingInformation><p><b>Table S1.</b>
 Supporting information in accordance with the CONSORT Statement 2001 checklist used in reporting randomized trials.</p>
<p>Please note: Wiley‐Blackwell is not responsible for the content or functionality of any supporting materials supplied by the authors. Any queries (other than missing material) should be directed to the corresponding author for the article.</p>
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<abstractGroup><abstract type="main" xml:lang="en"><!--

          
            Sanz M, Lorenzo R, Aranda JJ, Martin C, Orsini M. Clinical evaluation of a new collagen matrix (Mucograft^® prototype) to enhance the width of keratinized tissue in patients with fixed prosthetic restorations: a randomized prospective clinical trial. J Clin Periodontol 2009; 36: 868–876. doi: 10.1111/j.1600-051X.2009.01460.x.
        
--><title type="main">Abstract</title>
<p><b>Aim: </b>
 The aim of this study was to test a new collagen matrix (CM) aimed to increase keratinized gingiva/mucosa when compared with the free connective tissue graft (CTG).</p>
<p><b>Material and Methods: </b>
 This randomized longitudinal parallel controlled clinical trial studied 20 patients with at least one location with minimal keratinized tissue (<inlineGraphic alt="leqslant R: less-than-or-eq, slant" extraInfo="nonStandardEntity" location="les.gif" href=""></inlineGraphic>
1 mm).</p>
<p><b>Main Outcome Measure: </b>
 The 6‐month width of keratinized tissue. As secondary outcomes, the aesthetic outlook, the maintenance of periodontal health and the patient morbidity were assessed pre‐operatively at 1, 3 and 6 months.</p>
<p><b>Results: </b>
 At 6 months, the CTG attained a mean width of keratinized tissue of 2.6 (0.9) mm, while the CM was 2.5 (0.9) mm, these differences being insignificant. In both groups, there was a marked contraction (60% and 67%, respectively) although the periodontal parameters were not affected. The CM group had a significantly lower patient morbidity (pain and medication intake) as well as reduced surgery time.</p>
<p><b>Conclusions: </b>
 These results prove that this new CM was as effective and predictable as the CTG for attaining a band of keratinized tissue, but its use was associated with a significantly lower patient morbidity.</p>
</abstract>
</abstractGroup>
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<noteGroup><note xml:id="fn1" numbered="no"><p><b>Conflict of interest and source of funding statement</b>
               The authors declare that there are no conflict of interests in this study. This study was partially supported by a research grant from Geistlich Pharma.</p>
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<name type="personal"><namePart type="given">Mariano</namePart>
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<abstract>Aim: The aim of this study was to test a new collagen matrix (CM) aimed to increase keratinized gingiva/mucosa when compared with the free connective tissue graft (CTG).</abstract>
<abstract>Material and Methods: This randomized longitudinal parallel controlled clinical trial studied 20 patients with at least one location with minimal keratinized tissue (1 mm).</abstract>
<abstract>Main Outcome Measure: The 6‐month width of keratinized tissue. As secondary outcomes, the aesthetic outlook, the maintenance of periodontal health and the patient morbidity were assessed pre‐operatively at 1, 3 and 6 months.</abstract>
<abstract>Results: At 6 months, the CTG attained a mean width of keratinized tissue of 2.6 (0.9) mm, while the CM was 2.5 (0.9) mm, these differences being insignificant. In both groups, there was a marked contraction (60% and 67%, respectively) although the periodontal parameters were not affected. The CM group had a significantly lower patient morbidity (pain and medication intake) as well as reduced surgery time.</abstract>
<abstract>Conclusions: These results prove that this new CM was as effective and predictable as the CTG for attaining a band of keratinized tissue, but its use was associated with a significantly lower patient morbidity.</abstract>
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Clinical evaluation of a new collagen matrix (Mucograft® prototype) to enhance the width of keratinized tissue in patients with fixed prosthetic restorations: a randomized prospective clinical trial

Clinical evaluation of a new collagen matrix (Mucograft® prototype) to enhance the width of keratinized tissue in patients with fixed prosthetic restorations: a randomized prospective clinical trial

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