The efficacy of a topical gel with triester glycerol oxide in denture‐related mucosal injuries
Identifieur interne : 004E82 ( Istex/Corpus ); précédent : 004E81; suivant : 004E83The efficacy of a topical gel with triester glycerol oxide in denture‐related mucosal injuries
Auteurs : Onur Geckili ; Kivanc Bektas-Kayhan ; Pinar Eren ; Tayfun Bilgin ; Meral UnurSource :
- Gerodontology [ 0734-0664 ] ; 2012-06.
English descriptors
- KwdEn :
- Adverse reactions, Aust dent, Clinical examination, Complete denture, Complete denture usage, Complete dentures, Dent, Dental stone, Denture, Denture areas, Denture bases, Denture placement, Denture stomatitis, Denture wearers, Discomfort scores, Edentulous, Edentulous patients, Exact test, Gerodontology, Gerodontology society, Glycerol, Intraoral discomfort, Istanbul university, John wiley sons gerodontology, Last session, Lesion, Maxillary tuberosity, Moderate healing, Mucosal, Mucosal injuries, Oral mucosa, Oral mucosal conditions, Oral mucosal lesions, Oral pathol, Oral pathology, Oral rehabil, Oxide, Parafunctional activity, Patient satisfaction, Pilot study, Placebo, Placebo group, Placebo groups, Posterior portion, Prosthet dent, Queisser pharma, Removable dentures, Study protocol, Tissue adaptation, Topical, Triester, Triester glycerol oxide, Ulceration, Wilcoxon test.
- Teeft :
- Adverse reactions, Aust dent, Clinical examination, Complete denture, Complete denture usage, Complete dentures, Dent, Dental stone, Denture, Denture areas, Denture bases, Denture placement, Denture stomatitis, Denture wearers, Discomfort scores, Edentulous, Edentulous patients, Exact test, Gerodontology, Gerodontology society, Glycerol, Intraoral discomfort, Istanbul university, John wiley sons gerodontology, Last session, Lesion, Maxillary tuberosity, Moderate healing, Mucosal, Mucosal injuries, Oral mucosa, Oral mucosal conditions, Oral mucosal lesions, Oral pathol, Oral pathology, Oral rehabil, Oxide, Parafunctional activity, Patient satisfaction, Pilot study, Placebo, Placebo group, Placebo groups, Posterior portion, Prosthet dent, Queisser pharma, Removable dentures, Study protocol, Tissue adaptation, Topical, Triester, Triester glycerol oxide, Ulceration, Wilcoxon test.
Abstract
doi: 10.1111/j.1741‐2358.2011.00549.x
The efficacy of a topical gel with triester glycerol oxide in denture‐related mucosal injuries
Url:
DOI: 10.1111/j.1741-2358.2011.00549.x
Links to Exploration step
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<profileDesc><abstract xml:lang="en" style="main"><p><hi rend="italic">doi: 10.1111/j.1741‐2358.2011.00549.x</hi>
<hi rend="bold">The efficacy of a topical gel with triester glycerol oxide in denture‐related mucosal injuries</hi>
</p>
<p><hi rend="bold">Objective: </hi>
The efficacy of a topical gel with triester glycerol oxide for treating ulcerations related to new complete dentures was studied and compared with a placebo gel.</p>
<p><hi rend="bold">Materials and methods: </hi>
Fifty edentulous patients were enrolled in this double‐blind clinical study. All subjects received new maxillary and mandibular complete dentures and were recalled 1, 3 and 7 days after denture placement. Twenty‐five subjects received topical gel with triester glycerol oxide (TGO), and 25 subjects received topical gel without TGO. At each visit, pain and discomfort with the new dentures was assessed, and at the last visit, healing of ulcerations was also graded by a clinician. Subjects also graded the gel’s taste, smell and ease of use.</p>
<p><hi rend="bold">Results: </hi>
Specifically, there was no statistically significant difference in ulcer healing (<hi rend="italic">p </hi>
><hi rend="italic"> </hi>
0.05), ratings of smell, taste and ease of use (<hi rend="italic">p </hi>
><hi rend="italic"> </hi>
0.05) or pain and discomfort scores (<hi rend="italic">p </hi>
><hi rend="italic"> </hi>
0.05). However, within‐group differences were observed in pain and discomfort scores between follow‐up sessions (<hi rend="italic">p </hi>
=<hi rend="italic"> </hi>
0.01 for all comparisons).</p>
<p><hi rend="bold">Conclusion: </hi>
Clinically, TGO gel is not effective in the treatment of mucosal injuries occurring following placement of complete dentures.</p>
</abstract>
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<correspondenceTo>Onur Geckili, Department of Prosthodontics, Faculty of Dentistry, Istanbul University, 2nd floor, Capa‐Istanbul, Turkey.
Tel.: +90 212 414 20 20 ext. 30256
Fax: +90 212 535 25 85
E‐mail: <email>geckili@istanbul.edu.tr</email>
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<titleGroup><title type="main">The efficacy of a topical gel with triester glycerol oxide in denture‐related mucosal injuries</title>
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<abstractGroup><abstract type="main" xml:lang="en"><p><i>doi: 10.1111/j.1741‐2358.2011.00549.x</i>
<b>The efficacy of a topical gel with triester glycerol oxide in denture‐related mucosal injuries</b>
</p>
<p><b>Objective: </b>
The efficacy of a topical gel with triester glycerol oxide for treating ulcerations related to new complete dentures was studied and compared with a placebo gel.</p>
<p><b>Materials and methods: </b>
Fifty edentulous patients were enrolled in this double‐blind clinical study. All subjects received new maxillary and mandibular complete dentures and were recalled 1, 3 and 7 days after denture placement. Twenty‐five subjects received topical gel with triester glycerol oxide (TGO), and 25 subjects received topical gel without TGO. At each visit, pain and discomfort with the new dentures was assessed, and at the last visit, healing of ulcerations was also graded by a clinician. Subjects also graded the gel’s taste, smell and ease of use.</p>
<p><b>Results: </b>
Specifically, there was no statistically significant difference in ulcer healing (<i>p </i>
><i> </i>
0.05), ratings of smell, taste and ease of use (<i>p </i>
><i> </i>
0.05) or pain and discomfort scores (<i>p </i>
><i> </i>
0.05). However, within‐group differences were observed in pain and discomfort scores between follow‐up sessions (<i>p </i>
=<i> </i>
0.01 for all comparisons).</p>
<p><b>Conclusion: </b>
Clinically, TGO gel is not effective in the treatment of mucosal injuries occurring following placement of complete dentures.</p>
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<abstract>doi: 10.1111/j.1741‐2358.2011.00549.x
The efficacy of a topical gel with triester glycerol oxide in denture‐related mucosal injuries</abstract>
<abstract>Objective: The efficacy of a topical gel with triester glycerol oxide for treating ulcerations related to new complete dentures was studied and compared with a placebo gel.</abstract>
<abstract>Materials and methods: Fifty edentulous patients were enrolled in this double‐blind clinical study. All subjects received new maxillary and mandibular complete dentures and were recalled 1, 3 and 7 days after denture placement. Twenty‐five subjects received topical gel with triester glycerol oxide (TGO), and 25 subjects received topical gel without TGO. At each visit, pain and discomfort with the new dentures was assessed, and at the last visit, healing of ulcerations was also graded by a clinician. Subjects also graded the gel’s taste, smell and ease of use.</abstract>
<abstract>Results: Specifically, there was no statistically significant difference in ulcer healing (p > 0.05), ratings of smell, taste and ease of use (p > 0.05) or pain and discomfort scores (p > 0.05). However, within‐group differences were observed in pain and discomfort scores between follow‐up sessions (p = 0.01 for all comparisons).</abstract>
<abstract>Conclusion: Clinically, TGO gel is not effective in the treatment of mucosal injuries occurring following placement of complete dentures.</abstract>
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