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The efficacy of a topical gel with triester glycerol oxide in denture‐related mucosal injuries

Identifieur interne : 004E82 ( Istex/Corpus ); précédent : 004E81; suivant : 004E83

The efficacy of a topical gel with triester glycerol oxide in denture‐related mucosal injuries

Auteurs : Onur Geckili ; Kivanc Bektas-Kayhan ; Pinar Eren ; Tayfun Bilgin ; Meral Unur

Source :

Gerodontology [ 0734-0664 ] ; 2012-06.

RBID : ISTEX:9D9478A08F275C6F5E5DA1530F616A03EDF60CCF

English descriptors

Abstract

doi: 10.1111/j.1741‐2358.2011.00549.x   The efficacy of a topical gel with triester glycerol oxide in denture‐related mucosal injuries

Url:

https://api.istex.fr/document/9D9478A08F275C6F5E5DA1530F616A03EDF60CCF/fulltext/pdf

DOI: 10.1111/j.1741-2358.2011.00549.x

Links to Exploration step

ISTEX:9D9478A08F275C6F5E5DA1530F616A03EDF60CCF

Le document en format XML

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<profileDesc><abstract xml:lang="en" style="main"><p><hi rend="italic">doi: 10.1111/j.1741‐2358.2011.00549.x</hi>
           
               <hi rend="bold">The efficacy of a topical gel with triester glycerol oxide in denture‐related mucosal injuries</hi>
</p>
<p><hi rend="bold">Objective: </hi>
 The efficacy of a topical gel with triester glycerol oxide for treating ulcerations related to new complete dentures was studied and compared with a placebo gel.</p>
<p><hi rend="bold">Materials and methods: </hi>
 Fifty edentulous patients were enrolled in this double‐blind clinical study. All subjects received new maxillary and mandibular complete dentures and were recalled 1, 3 and 7 days after denture placement. Twenty‐five subjects received topical gel with triester glycerol oxide (TGO), and 25 subjects received topical gel without TGO. At each visit, pain and discomfort with the new dentures was assessed, and at the last visit, healing of ulcerations was also graded by a clinician. Subjects also graded the gel’s taste, smell and ease of use.</p>
<p><hi rend="bold">Results: </hi>
 Specifically, there was no statistically significant difference in ulcer healing (<hi rend="italic">p </hi>
><hi rend="italic"> </hi>
0.05), ratings of smell, taste and ease of use (<hi rend="italic">p </hi>
><hi rend="italic"> </hi>
0.05) or pain and discomfort scores (<hi rend="italic">p </hi>
><hi rend="italic"> </hi>
0.05). However, within‐group differences were observed in pain and discomfort scores between follow‐up sessions (<hi rend="italic">p </hi>
=<hi rend="italic"> </hi>
0.01 for all comparisons).</p>
<p><hi rend="bold">Conclusion: </hi>
 Clinically, TGO gel is not effective in the treatment of mucosal injuries occurring following placement of complete dentures.</p>
</abstract>
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<copyright>© 2011 The Gerodontology Society and John Wiley & Sons A/S</copyright>
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<correspondenceTo>Onur Geckili, Department of Prosthodontics, Faculty of Dentistry, Istanbul University, 2nd floor, Capa‐Istanbul, Turkey.  Tel.: +90 212 414 20 20 ext. 30256  Fax: +90 212 535 25 85  E‐mail: <email>geckili@istanbul.edu.tr</email>
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<titleGroup><title type="main">The efficacy of a topical gel with triester glycerol oxide in denture‐related mucosal injuries</title>
<title type="shortAuthors"><i>O. Geckili et al.</i>
</title>
<title type="short"><i>Topical gel with triester glycerol oxide</i>
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<familyName>Eren</familyName>
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<creator creatorRole="author" xml:id="cr4" affiliationRef="#a1"><personName><givenNames>Tayfun</givenNames>
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<abstractGroup><abstract type="main" xml:lang="en"><p><i>doi: 10.1111/j.1741‐2358.2011.00549.x</i>
           
          <b>The efficacy of a topical gel with triester glycerol oxide in denture‐related mucosal injuries</b>
</p>
<p><b>Objective: </b>
 The efficacy of a topical gel with triester glycerol oxide for treating ulcerations related to new complete dentures was studied and compared with a placebo gel.</p>
<p><b>Materials and methods: </b>
 Fifty edentulous patients were enrolled in this double‐blind clinical study. All subjects received new maxillary and mandibular complete dentures and were recalled 1, 3 and 7 days after denture placement. Twenty‐five subjects received topical gel with triester glycerol oxide (TGO), and 25 subjects received topical gel without TGO. At each visit, pain and discomfort with the new dentures was assessed, and at the last visit, healing of ulcerations was also graded by a clinician. Subjects also graded the gel’s taste, smell and ease of use.</p>
<p><b>Results: </b>
 Specifically, there was no statistically significant difference in ulcer healing (<i>p </i>
><i> </i>
0.05), ratings of smell, taste and ease of use (<i>p </i>
><i> </i>
0.05) or pain and discomfort scores (<i>p </i>
><i> </i>
0.05). However, within‐group differences were observed in pain and discomfort scores between follow‐up sessions (<i>p </i>
=<i> </i>
0.01 for all comparisons).</p>
<p><b>Conclusion: </b>
 Clinically, TGO gel is not effective in the treatment of mucosal injuries occurring following placement of complete dentures.</p>
</abstract>
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<abstract>doi: 10.1111/j.1741‐2358.2011.00549.x   The efficacy of a topical gel with triester glycerol oxide in denture‐related mucosal injuries</abstract>
<abstract>Objective:  The efficacy of a topical gel with triester glycerol oxide for treating ulcerations related to new complete dentures was studied and compared with a placebo gel.</abstract>
<abstract>Materials and methods:  Fifty edentulous patients were enrolled in this double‐blind clinical study. All subjects received new maxillary and mandibular complete dentures and were recalled 1, 3 and 7 days after denture placement. Twenty‐five subjects received topical gel with triester glycerol oxide (TGO), and 25 subjects received topical gel without TGO. At each visit, pain and discomfort with the new dentures was assessed, and at the last visit, healing of ulcerations was also graded by a clinician. Subjects also graded the gel’s taste, smell and ease of use.</abstract>
<abstract>Results:  Specifically, there was no statistically significant difference in ulcer healing (p > 0.05), ratings of smell, taste and ease of use (p > 0.05) or pain and discomfort scores (p > 0.05). However, within‐group differences were observed in pain and discomfort scores between follow‐up sessions (p = 0.01 for all comparisons).</abstract>
<abstract>Conclusion:  Clinically, TGO gel is not effective in the treatment of mucosal injuries occurring following placement of complete dentures.</abstract>
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The efficacy of a topical gel with triester glycerol oxide in denture‐related mucosal injuries

The efficacy of a topical gel with triester glycerol oxide in denture‐related mucosal injuries

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