Signs and symptoms in patients with salivary gland hypofunction.
Identifieur interne : 003704 ( Istex/Corpus ); précédent : 003703; suivant : 003705Signs and symptoms in patients with salivary gland hypofunction.
Auteurs : L. P. Longman ; S. M. Higham ; R. Bucknall ; S. B. Kaye ; W. M. Edgar ; E. A. FieldSource :
- Postgraduate Medical Journal [ 0032-5473 ] ; 1997-02.
English descriptors
- KwdEn :
- Clinical evidence, Clinical history, Daily feeling, Dent assoc, Dental practitioners, Devastating effect, Different categories, Dryness, Early recognition, Further investigations, Gland, Gland hypofunction, Hypofunction, Laboratory findings, Lacrimal, Lacrimal flow, Objective evidence, Oral candidosis, Oral dryness, Oral dysfunction, Oral function, Oral health, Oral mucosa, Oral symptoms, Positive response, Positive responses, Positive result, Positive schirmer test, Potential value, Preliminary criteria, Present study, Primary syndrome, Probable cause, Prospective study, Rheumatoid arthritis, Salivary, Salivary flow, Salivary gland, Salivary gland dysfunction, Salivary gland hypofunction, Salivary gland hypofunction number, Secondary syndrome, Significant difference, Specialist investigation, Statistical analysis, Symptom, Syndrome, Systemic disease, Unstimulated flow rate, Vaginal dryness, Whole saliva, Whole saliva flow, Wide range, Xerostomia.
- Teeft :
- Clinical evidence, Clinical history, Daily feeling, Dent assoc, Dental practitioners, Devastating effect, Different categories, Dryness, Early recognition, Further investigations, Gland, Gland hypofunction, Hypofunction, Laboratory findings, Lacrimal, Lacrimal flow, Objective evidence, Oral candidosis, Oral dryness, Oral dysfunction, Oral function, Oral health, Oral mucosa, Oral symptoms, Positive response, Positive responses, Positive result, Positive schirmer test, Potential value, Preliminary criteria, Present study, Primary syndrome, Probable cause, Prospective study, Rheumatoid arthritis, Salivary, Salivary flow, Salivary gland, Salivary gland dysfunction, Salivary gland hypofunction, Salivary gland hypofunction number, Secondary syndrome, Significant difference, Specialist investigation, Statistical analysis, Symptom, Syndrome, Systemic disease, Unstimulated flow rate, Vaginal dryness, Whole saliva, Whole saliva flow, Wide range, Xerostomia.
Abstract
Salivary gland hypofunction can have a devastating effect on oral health and may be an indicator of systemic disease such as Sjögren's syndrome. This prospective study investigates the oral and non-oral signs and symptoms in 120 patients with objective evidence of salivary gland hypofunction (ie, an unstimulated whole salivary flow of < 0.2 ml/min). Patients were questioned about symptoms associated with decreased oral function; non-oral symptoms were also noted. The underlying cause of salivary gland hypofunction was established on the basis of clinical and laboratory findings and further investigations. Eighty-five per cent of patients reported symptoms of decreased oral function in addition to oral dryness. Non-oral signs and symptoms were reported by 106 patients. Fifty-three per cent of patients were diagnosed as having Sjögren's syndrome. The prevalence of the following non-oral signs and symptoms were significantly higher in patients with Sjögren's syndrome, than in those without; a history of dry/irritated eyes, salivary gland swelling, dry skin and reduced lacrimal flow. Salivary gland hypofunction is associated with a wide range of oral and non-oral signs and symptoms. Several of these are of potential value as triggers for the clinician to identify patients with Sjögren's syndrome, and should serve to prompt referral for specialist investigation.
Url:
DOI: 10.1136/pgmj.73.856.93
Links to Exploration step
ISTEX:6F2DEC656BB8F0F3AA9EBE0063B3BB71A3B5BE8BLe document en format XML
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This prospective study investigates the oral and non-oral signs and symptoms in 120 patients with objective evidence of salivary gland hypofunction (ie, an unstimulated whole salivary flow of < 0.2 ml/min). Patients were questioned about symptoms associated with decreased oral function; non-oral symptoms were also noted. The underlying cause of salivary gland hypofunction was established on the basis of clinical and laboratory findings and further investigations. Eighty-five per cent of patients reported symptoms of decreased oral function in addition to oral dryness. Non-oral signs and symptoms were reported by 106 patients. Fifty-three per cent of patients were diagnosed as having Sjögren's syndrome. The prevalence of the following non-oral signs and symptoms were significantly higher in patients with Sjögren's syndrome, than in those without; a history of dry/irritated eyes, salivary gland swelling, dry skin and reduced lacrimal flow. Salivary gland hypofunction is associated with a wide range of oral and non-oral signs and symptoms. Several of these are of potential value as triggers for the clinician to identify patients with Sjögren's syndrome, and should serve to prompt referral for specialist investigation.</div></front></TEI><istex><corpusName>bmj</corpusName><keywords><teeft><json:string>hypofunction</json:string><json:string>salivary</json:string><json:string>salivary gland hypofunction</json:string><json:string>xerostomia</json:string><json:string>salivary gland</json:string><json:string>syndrome</json:string><json:string>oral dryness</json:string><json:string>positive response</json:string><json:string>lacrimal</json:string><json:string>oral function</json:string><json:string>objective evidence</json:string><json:string>lacrimal flow</json:string><json:string>salivary flow</json:string><json:string>systemic disease</json:string><json:string>oral health</json:string><json:string>gland hypofunction</json:string><json:string>wide range</json:string><json:string>symptom</json:string><json:string>dryness</json:string><json:string>gland</json:string><json:string>salivary gland dysfunction</json:string><json:string>oral symptoms</json:string><json:string>further investigations</json:string><json:string>vaginal dryness</json:string><json:string>primary syndrome</json:string><json:string>positive responses</json:string><json:string>different categories</json:string><json:string>dent assoc</json:string><json:string>early recognition</json:string><json:string>dental practitioners</json:string><json:string>clinical history</json:string><json:string>prospective study</json:string><json:string>rheumatoid arthritis</json:string><json:string>oral mucosa</json:string><json:string>clinical evidence</json:string><json:string>salivary gland hypofunction number</json:string><json:string>potential value</json:string><json:string>positive schirmer test</json:string><json:string>whole saliva flow</json:string><json:string>unstimulated flow rate</json:string><json:string>probable cause</json:string><json:string>statistical analysis</json:string><json:string>secondary syndrome</json:string><json:string>present study</json:string><json:string>whole saliva</json:string><json:string>preliminary criteria</json:string><json:string>daily feeling</json:string><json:string>oral dysfunction</json:string><json:string>specialist investigation</json:string><json:string>positive result</json:string><json:string>laboratory findings</json:string><json:string>oral candidosis</json:string><json:string>devastating effect</json:string><json:string>significant difference</json:string></teeft></keywords><author><json:item><name>L. P. Longman</name><affiliations><json:string>Department of Clinical Dental Sciences, Liverpool University Dental Hospital, UK.</json:string></affiliations></json:item><json:item><name>S. M. Higham</name><affiliations><json:string>Department of Clinical Dental Sciences, Liverpool University Dental Hospital, UK.</json:string></affiliations></json:item><json:item><name>R. Bucknall</name><affiliations><json:string>Department of Clinical Dental Sciences, Liverpool University Dental Hospital, UK.</json:string></affiliations></json:item><json:item><name>S. B. Kaye</name><affiliations><json:string>Department of Clinical Dental Sciences, Liverpool University Dental Hospital, UK.</json:string></affiliations></json:item><json:item><name>W. M. Edgar</name><affiliations><json:string>Department of Clinical Dental Sciences, Liverpool University Dental Hospital, UK.</json:string></affiliations></json:item><json:item><name>E. A. Field</name><affiliations><json:string>Department of Clinical Dental Sciences, Liverpool University Dental Hospital, UK.</json:string></affiliations></json:item></author><arkIstex>ark:/67375/NVC-D22DP2VG-1</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>research-article</json:string></originalGenre><abstract>Salivary gland hypofunction can have a devastating effect on oral health and may be an indicator of systemic disease such as Sjögren's syndrome. This prospective study investigates the oral and non-oral signs and symptoms in 120 patients with objective evidence of salivary gland hypofunction (ie, an unstimulated whole salivary flow of > 0.2 ml/min). Patients were questioned about symptoms associated with decreased oral function; non-oral symptoms were also noted. The underlying cause of salivary gland hypofunction was established on the basis of clinical and laboratory findings and further investigations. Eighty-five per cent of patients reported symptoms of decreased oral function in addition to oral dryness. Non-oral signs and symptoms were reported by 106 patients. Fifty-three per cent of patients were diagnosed as having Sjögren's syndrome. The prevalence of the following non-oral signs and symptoms were significantly higher in patients with Sjögren's syndrome, than in those without; a history of dry/irritated eyes, salivary gland swelling, dry skin and reduced lacrimal flow. Salivary gland hypofunction is associated with a wide range of oral and non-oral signs and symptoms. 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Xerostomia</json:string><json:string>Subjective</json:string><json:string>Orion Diagnostica</json:string></persName><placeName><json:string>Finland</json:string><json:string>Liverpool</json:string><json:string>York</json:string><json:string>Espoo</json:string></placeName><ref_url></ref_url><ref_bibl><json:string>Vitali et al</json:string></ref_bibl><bibl></bibl></unitex></namedEntities><ark><json:string>ark:/67375/NVC-D22DP2VG-1</json:string></ark><categories><wos><json:string>1 - science</json:string><json:string>2 - medicine, general & internal</json:string></wos><scienceMetrix><json:string>1 - health sciences</json:string><json:string>2 - clinical medicine</json:string><json:string>3 - general & internal medicine</json:string></scienceMetrix><scopus><json:string>1 - Health Sciences</json:string><json:string>2 - Medicine</json:string><json:string>3 - General Medicine</json:string></scopus><inist><json:string>1 - sciences appliquees, technologies et medecines</json:string><json:string>2 - sciences biologiques et medicales</json:string><json:string>3 - sciences medicales</json:string></inist></categories><publicationDate>1997</publicationDate><copyrightDate>1997</copyrightDate><doi><json:string>10.1136/pgmj.73.856.93</json:string></doi><id>6F2DEC656BB8F0F3AA9EBE0063B3BB71A3B5BE8B</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/6F2DEC656BB8F0F3AA9EBE0063B3BB71A3B5BE8B/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/6F2DEC656BB8F0F3AA9EBE0063B3BB71A3B5BE8B/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/6F2DEC656BB8F0F3AA9EBE0063B3BB71A3B5BE8B/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Signs and symptoms in patients with salivary gland hypofunction.</title><respStmt><resp>Références bibliographiques récupérées via GROBID</resp><name resp="ISTEX-API">ISTEX-API (INIST-CNRS)</name></respStmt></titleStmt><publicationStmt><authority>ISTEX</authority><publisher scheme="https://publisher-list.data.istex.fr">The Fellowship of Postgraduate Medicine</publisher><availability><licence><p>© British Medical Journal Publishing Group</p></licence><p scheme="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-7M42M2QJ-2">bmj</p></availability><date>1997-02-01</date></publicationStmt><notesStmt><note type="research-article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</note><note type="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Signs and symptoms in patients with salivary gland hypofunction.</title><author xml:id="author-0000"><persName><forename type="first">L. P.</forename><surname>Longman</surname></persName><affiliation>Department of Clinical Dental Sciences, Liverpool University Dental Hospital, UK.</affiliation></author><author xml:id="author-0001"><persName><forename type="first">S. M.</forename><surname>Higham</surname></persName><affiliation>Department of Clinical Dental Sciences, Liverpool University Dental Hospital, UK.</affiliation></author><author xml:id="author-0002"><persName><forename type="first">R.</forename><surname>Bucknall</surname></persName><affiliation>Department of Clinical Dental Sciences, Liverpool University Dental Hospital, UK.</affiliation></author><author xml:id="author-0003"><persName><forename type="first">S. B.</forename><surname>Kaye</surname></persName><affiliation>Department of Clinical Dental Sciences, Liverpool University Dental Hospital, UK.</affiliation></author><author xml:id="author-0004"><persName><forename type="first">W. M.</forename><surname>Edgar</surname></persName><affiliation>Department of Clinical Dental Sciences, Liverpool University Dental Hospital, UK.</affiliation></author><author xml:id="author-0005"><persName><forename type="first">E. A.</forename><surname>Field</surname></persName><affiliation>Department of Clinical Dental Sciences, Liverpool University Dental Hospital, UK.</affiliation></author><idno type="istex">6F2DEC656BB8F0F3AA9EBE0063B3BB71A3B5BE8B</idno><idno type="ark">ark:/67375/NVC-D22DP2VG-1</idno><idno type="DOI">10.1136/pgmj.73.856.93</idno><idno type="href">postgradmedj-73-93.pdf</idno><idno type="PMID">9122105</idno><idno type="local">postgradmedj;73/856/93</idno></analytic><monogr><title level="j">Postgraduate Medical Journal</title><title level="j" type="abbrev">Postgrad Med J</title><idno type="pISSN">0032-5473</idno><idno type="eISSN">1469-0756</idno><idno type="PublisherID-hwp">postgradmedj</idno><idno type="PublisherID-nlm-ta">Postgrad Med J</idno><imprint><publisher>The Fellowship of Postgraduate Medicine</publisher><date type="published" when="1997-02"></date><biblScope unit="volume">73</biblScope><biblScope unit="issue">856</biblScope><biblScope unit="page" from="93">93</biblScope></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1997-02-01</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Salivary gland hypofunction can have a devastating effect on oral health and may be an indicator of systemic disease such as Sjögren's syndrome. This prospective study investigates the oral and non-oral signs and symptoms in 120 patients with objective evidence of salivary gland hypofunction (ie, an unstimulated whole salivary flow of < 0.2 ml/min). Patients were questioned about symptoms associated with decreased oral function; non-oral symptoms were also noted. The underlying cause of salivary gland hypofunction was established on the basis of clinical and laboratory findings and further investigations. Eighty-five per cent of patients reported symptoms of decreased oral function in addition to oral dryness. Non-oral signs and symptoms were reported by 106 patients. Fifty-three per cent of patients were diagnosed as having Sjögren's syndrome. The prevalence of the following non-oral signs and symptoms were significantly higher in patients with Sjögren's syndrome, than in those without; a history of dry/irritated eyes, salivary gland swelling, dry skin and reduced lacrimal flow. Salivary gland hypofunction is associated with a wide range of oral and non-oral signs and symptoms. Several of these are of potential value as triggers for the clinician to identify patients with Sjögren's syndrome, and should serve to prompt referral for specialist investigation.</p></abstract></profileDesc><revisionDesc><change when="1997-02-01">Created</change><change when="1997-02">Published</change><change xml:id="refBibs-istex" who="#ISTEX-API" when="2017-10-17">References added</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/6F2DEC656BB8F0F3AA9EBE0063B3BB71A3B5BE8B/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="corpus bmj" wicri:toSee="no header"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="no"</istex:xmlDeclaration><istex:docType PUBLIC="-//NLM//DTD Journal Archiving and Interchange DTD v2.3 20070202//EN" URI="archivearticle.dtd" name="istex:docType"></istex:docType><istex:document><article article-type="research-article" xml:lang="EN"><front><journal-meta><journal-id journal-id-type="hwp">postgradmedj</journal-id><journal-id journal-id-type="nlm-ta">Postgrad Med J</journal-id><journal-id journal-id-type="pmc">postmedj</journal-id><journal-title>Postgraduate Medical Journal</journal-title><abbrev-journal-title abbrev-type="publisher">Postgrad Med J</abbrev-journal-title><issn pub-type="ppub">0032-5473</issn><issn pub-type="epub">1469-0756</issn><publisher><publisher-name>The Fellowship of Postgraduate Medicine</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">9122105</article-id><article-id pub-id-type="other">postgradmedj;73/856/93</article-id><article-id pub-id-type="doi">10.1136/pgmj.73.856.93</article-id><article-id pub-id-type="other">93</article-id><article-id pub-id-type="other">pgmj.73.856.93</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>Signs and symptoms in patients with salivary gland hypofunction.</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Longman</surname><given-names>L. P.</given-names></name></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Higham</surname><given-names>S. M.</given-names></name></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Bucknall</surname><given-names>R.</given-names></name></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Kaye</surname><given-names>S. B.</given-names></name></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Edgar</surname><given-names>W. M.</given-names></name></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Field</surname><given-names>E. A.</given-names></name></contrib></contrib-group><aff>Department of Clinical Dental Sciences, Liverpool University Dental Hospital, UK.</aff><pub-date pub-type="ppub"><month>2</month><year>1997</year></pub-date><pub-date pub-type="epub"><day>1</day><month>2</month><year>1997</year></pub-date><volume>73</volume><volume-id pub-id-type="other">73</volume-id><volume-id pub-id-type="other">73</volume-id><issue>856</issue><issue-id pub-id-type="other">postgradmedj;73/856</issue-id><issue-id pub-id-type="other">856</issue-id><issue-id pub-id-type="other">73/856</issue-id><fpage>93</fpage><self-uri content-type="pdf" xlink:role="full-text" xlink:href="postgradmedj-73-93.pdf"></self-uri><abstract><p>Salivary gland hypofunction can have a devastating effect on oral health and may be an indicator of systemic disease such as Sjögren's syndrome. This prospective study investigates the oral and non-oral signs and symptoms in 120 patients with objective evidence of salivary gland hypofunction (ie, an unstimulated whole salivary flow of < 0.2 ml/min). Patients were questioned about symptoms associated with decreased oral function; non-oral symptoms were also noted. The underlying cause of salivary gland hypofunction was established on the basis of clinical and laboratory findings and further investigations. Eighty-five per cent of patients reported symptoms of decreased oral function in addition to oral dryness. Non-oral signs and symptoms were reported by 106 patients. Fifty-three per cent of patients were diagnosed as having Sjögren's syndrome. The prevalence of the following non-oral signs and symptoms were significantly higher in patients with Sjögren's syndrome, than in those without; a history of dry/irritated eyes, salivary gland swelling, dry skin and reduced lacrimal flow. Salivary gland hypofunction is associated with a wide range of oral and non-oral signs and symptoms. Several of these are of potential value as triggers for the clinician to identify patients with Sjögren's syndrome, and should serve to prompt referral for specialist investigation.</p></abstract></article-meta></front></article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Signs and symptoms in patients with salivary gland hypofunction.</title></titleInfo><titleInfo type="alternative" lang="en" contentType="CDATA"><title>Signs and symptoms in patients with salivary gland hypofunction.</title></titleInfo><name type="personal"><namePart type="given">L. P.</namePart><namePart type="family">Longman</namePart><affiliation>Department of Clinical Dental Sciences, Liverpool University Dental Hospital, UK.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S. M.</namePart><namePart type="family">Higham</namePart><affiliation>Department of Clinical Dental Sciences, Liverpool University Dental Hospital, UK.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R.</namePart><namePart type="family">Bucknall</namePart><affiliation>Department of Clinical Dental Sciences, Liverpool University Dental Hospital, UK.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S. B.</namePart><namePart type="family">Kaye</namePart><affiliation>Department of Clinical Dental Sciences, Liverpool University Dental Hospital, UK.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">W. M.</namePart><namePart type="family">Edgar</namePart><affiliation>Department of Clinical Dental Sciences, Liverpool University Dental Hospital, UK.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E. A.</namePart><namePart type="family">Field</namePart><affiliation>Department of Clinical Dental Sciences, Liverpool University Dental Hospital, UK.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="research-article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</genre><originInfo><publisher>The Fellowship of Postgraduate Medicine</publisher><dateIssued encoding="w3cdtf">1997-02</dateIssued><dateCreated encoding="w3cdtf">1997-02-01</dateCreated><copyrightDate encoding="w3cdtf">1997</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><abstract lang="en">Salivary gland hypofunction can have a devastating effect on oral health and may be an indicator of systemic disease such as Sjögren's syndrome. This prospective study investigates the oral and non-oral signs and symptoms in 120 patients with objective evidence of salivary gland hypofunction (ie, an unstimulated whole salivary flow of < 0.2 ml/min). Patients were questioned about symptoms associated with decreased oral function; non-oral symptoms were also noted. The underlying cause of salivary gland hypofunction was established on the basis of clinical and laboratory findings and further investigations. Eighty-five per cent of patients reported symptoms of decreased oral function in addition to oral dryness. Non-oral signs and symptoms were reported by 106 patients. Fifty-three per cent of patients were diagnosed as having Sjögren's syndrome. The prevalence of the following non-oral signs and symptoms were significantly higher in patients with Sjögren's syndrome, than in those without; a history of dry/irritated eyes, salivary gland swelling, dry skin and reduced lacrimal flow. Salivary gland hypofunction is associated with a wide range of oral and non-oral signs and symptoms. Several of these are of potential value as triggers for the clinician to identify patients with Sjögren's syndrome, and should serve to prompt referral for specialist investigation.</abstract><relatedItem type="host"><titleInfo><title>Postgraduate Medical Journal</title></titleInfo><titleInfo type="abbreviated"><title>Postgrad Med J</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><identifier type="ISSN">0032-5473</identifier><identifier type="eISSN">1469-0756</identifier><identifier type="PublisherID-hwp">postgradmedj</identifier><identifier type="PublisherID-nlm-ta">Postgrad Med J</identifier><part><date>1997</date><detail type="volume"><caption>vol.</caption><number>73</number></detail><detail type="issue"><caption>no.</caption><number>856</number></detail><extent unit="pages"><start>93</start></extent></part></relatedItem><identifier type="istex">6F2DEC656BB8F0F3AA9EBE0063B3BB71A3B5BE8B</identifier><identifier type="ark">ark:/67375/NVC-D22DP2VG-1</identifier><identifier type="DOI">10.1136/pgmj.73.856.93</identifier><identifier type="href">postgradmedj-73-93.pdf</identifier><identifier type="PMID">9122105</identifier><identifier type="local">postgradmedj;73/856/93</identifier><accessCondition type="use and reproduction" contentType="copyright">© British Medical Journal Publishing Group</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-7M42M2QJ-2">bmj</recordContentSource><recordOrigin>© British Medical Journal Publishing Group</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/document/6F2DEC656BB8F0F3AA9EBE0063B3BB71A3B5BE8B/metadata/json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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