Immediate versus early non‐occlusal loading of dental implants placed flapless in partially edentulous patients: A 3‐year randomized clinical trial
Identifieur interne : 003431 ( Istex/Corpus ); précédent : 003430; suivant : 003432Immediate versus early non‐occlusal loading of dental implants placed flapless in partially edentulous patients: A 3‐year randomized clinical trial
Auteurs : Mauro Merli ; Marco Moscatelli ; Giorgia Mariotti ; Matteo Piemontese ; Michele NieriSource :
- Journal of Clinical Periodontology [ 0303-6979 ] ; 2012-02.
English descriptors
- KwdEn :
- Apless, Apless approach, Apless procedure, Apless technique, Baseline, Bone level, Clin periodontol, Clinical trial, Clinical view, Control group, Coronal point, Dental implants, Early loading, Early loading group, Edentulous, Edentulous patients, Esposito, European journal, Failure rates, Group assignment, Healing period, Health problems, Implant, Implant failure, Implant failures, Implant insertion, Implant placement, Implant site, Implant surface, Implant surgery, Implants research, Interaction term, International journal, John wiley sons, Lower bone level, Mandibular overdentures, Maxillary prostheses, Merli, Minimum torque, Multilevel model, Null hypothesis, Oral implantology, Oral maxillofacial implants, Parallel randomized, Partial dentures, Posterior mandible, Previous publication, Primary stability, Private clinic, Prosthesis, Prosthesis failure, Prosthetic complications, Prosthetic failure, Protocol deviation, Radiographic, Radiographic bone level, Radiographic data, Radiographic image, Radiographic outcome, Randomized, Sample size, Sensitivity analysis, Single implants, Statistical analysis, Systematic review, Test group, Work commitments.
- Teeft :
- Apless, Apless approach, Apless procedure, Apless technique, Baseline, Bone level, Clin periodontol, Clinical trial, Clinical view, Control group, Coronal point, Dental implants, Early loading, Early loading group, Edentulous, Edentulous patients, Esposito, European journal, Failure rates, Group assignment, Healing period, Health problems, Implant, Implant failure, Implant failures, Implant insertion, Implant placement, Implant site, Implant surface, Implant surgery, Implants research, Interaction term, International journal, John wiley sons, Lower bone level, Mandibular overdentures, Maxillary prostheses, Merli, Minimum torque, Multilevel model, Null hypothesis, Oral implantology, Oral maxillofacial implants, Parallel randomized, Partial dentures, Posterior mandible, Previous publication, Primary stability, Private clinic, Prosthesis, Prosthesis failure, Prosthetic complications, Prosthetic failure, Protocol deviation, Radiographic, Radiographic bone level, Radiographic data, Radiographic image, Radiographic outcome, Randomized, Sample size, Sensitivity analysis, Single implants, Statistical analysis, Systematic review, Test group, Work commitments.
Abstract
To compare immediate versus early non‐occlusal loading of dental implants placed flapless in a 3‐year, parallel group, randomized clinical trial.
Url:
DOI: 10.1111/j.1600-051X.2011.01821.x
Links to Exploration step
ISTEX:69C3CA503F554C74E81B67A6423E87DB3AC17A51Le document en format XML
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Aim
<p>To compare immediate <hi rend="italic">versus</hi> early non‐occlusal loading of dental implants placed flapless in a 3‐year, parallel group, randomized clinical trial.</p>
Materials and Methods
<p>The study was conducted in a private dental clinic between July 2005 and July 2010. Patients 18 years or older were randomized to receive implants for fixed partial dentures in cases of partial edentulism. The test group was represented by immediate non‐occlusal implant loading, whereas the control group was represented by early non‐occlusal implant loading. The outcome variables were implant failure, complications and radiographic bone level at implant sites 3 years after loading, measured from the implant–abutment junction to the most coronal point of bone‐to‐implant contact. Randomization was computer‐generated with allocation concealment by opaque sequentially numbered sealed envelopes, and the measurer was blinded to group assignment.</p>
Results
<p>Sixty patients were randomized: 30 to the immediately loaded group and 30 to the early loaded group. Four patients dropped out; however, the data of all patients were included in the analysis. No implant failure occurred. Two complications occurred in the control group and one in the test group. The mean bone level at 3 years was 1.91 mm for test group and 1.59 mm for control group. The adjusted difference in bone level was 0.26 mm (<hi rend="fc">CI</hi> 95% −0.08 to 0.59, <hi rend="italic">p</hi> = 0.1232).</p>
Conclusion
<p>The null hypothesis of no difference in failure rates, complications and bone level between implants that were loaded immediately or early at 3 years cannot be rejected in this randomized clinical trial.</p></abstract><textClass><keywords><term xml:id="jcpe1821-kwd-0001">dental implants</term><term xml:id="jcpe1821-kwd-0002">early loaded implant</term><term xml:id="jcpe1821-kwd-0003">failures</term><term xml:id="jcpe1821-kwd-0004">flapless implant</term><term xml:id="jcpe1821-kwd-0005">immediate loaded implant</term><term xml:id="jcpe1821-kwd-0006">non‐occlusal loading</term><term xml:id="jcpe1821-kwd-0007">radiographic data</term><term xml:id="jcpe1821-kwd-0008">randomized clinical trial</term></keywords><keywords rend="articleCategory"><term>Implant Therapy</term></keywords><keywords rend="tocHeading1"><term>Implant Therapy</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/69C3CA503F554C74E81B67A6423E87DB3AC17A51/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component type="serialArticle" version="2.0" xml:id="jcpe1821" xml:lang="en"><header><publicationMeta level="product"><doi origin="wiley" registered="yes">10.1111/(ISSN)1600-051X</doi><issn type="print">0303-6979</issn><issn type="electronic">1600-051X</issn><idGroup><id type="product" value="JCPE"></id></idGroup><titleGroup><title sort="JOURNAL OF CLINICAL PERIODONTOLOGY" type="main">Journal of Clinical Periodontology</title><title type="short">J Clin Periodontol</title></titleGroup></publicationMeta><publicationMeta level="part" position="20"><doi origin="wiley">10.1111/jcpe.2012.39.issue-2</doi><copyright ownership="publisher">Copyright © 2012 John Wiley & Sons A/S</copyright><numberingGroup><numbering type="journalVolume" number="39">39</numbering><numbering type="journalIssue">2</numbering></numberingGroup><coverDate startDate="2012-02">February 2012</coverDate></publicationMeta><publicationMeta level="unit" position="120" status="forIssue" type="article"><doi>10.1111/j.1600-051X.2011.01821.x</doi><idGroup><id type="unit" value="JCPE1821"></id></idGroup><countGroup><count number="7" type="pageTotal"></count></countGroup><titleGroup><title type="articleCategory">Implant Therapy</title><title type="tocHeading1">Implant Therapy</title></titleGroup><copyright ownership="publisher">© 2011 John Wiley & Sons A/S</copyright><eventGroup><event date="2011-10-16" type="manuscriptAccepted"></event><event agent="SPS" date="2011-11-01" type="xmlCreated"></event><event type="publishedOnlineEarlyUnpaginated" date="2011-11-28"></event><event type="firstOnline" date="2011-11-28"></event><event type="publishedOnlineFinalForm" date="2012-01-12"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:4.0.1" date="2014-03-19"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.3.4 mode:FullText" date="2015-02-25"></event></eventGroup><numberingGroup><numbering type="pageFirst">196</numbering><numbering type="pageLast">202</numbering></numberingGroup><correspondenceTo><lineatedText><line>Address:</line><line><i>M. Merli</i></line><line><i>Viale Settembrini 17/O 47923 Rimini</i></line><line><i>Italy</i></line><line>E‐mail: <email>mauromerli@gmail.com</email></line></lineatedText></correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:JCPE.JCPE1821.pdf"></link></linkGroup></publicationMeta><contentMeta><titleGroup><title type="main">Immediate <i>versus</i> early non‐occlusal loading of dental implants placed flapless in partially edentulous patients: A 3‐year randomized clinical trial</title><title type="shortAuthors">Merli et al.</title></titleGroup><creators><creator affiliationRef="#jcpe1821-aff-0001" creatorRole="author" xml:id="jcpe1821-cr-0001"><personName><givenNames>Mauro</givenNames> <familyName>Merli</familyName></personName></creator><creator affiliationRef="#jcpe1821-aff-0001" creatorRole="author" xml:id="jcpe1821-cr-0002"><personName><givenNames>Marco</givenNames> <familyName>Moscatelli</familyName></personName></creator><creator affiliationRef="#jcpe1821-aff-0001" creatorRole="author" xml:id="jcpe1821-cr-0003"><personName><givenNames>Giorgia</givenNames> <familyName>Mariotti</familyName></personName></creator><creator affiliationRef="#jcpe1821-aff-0002" creatorRole="author" xml:id="jcpe1821-cr-0004"><personName><givenNames>Matteo</givenNames> <familyName>Piemontese</familyName></personName></creator><creator affiliationRef="#jcpe1821-aff-0003" creatorRole="author" xml:id="jcpe1821-cr-0005"><personName><givenNames>Michele</givenNames> <familyName>Nieri</familyName></personName></creator></creators><affiliationGroup><affiliation countryCode="IT" type="organization" xml:id="jcpe1821-aff-0001"><orgName>Private practice</orgName> <address><city>Rimini</city> <country>Italy</country></address></affiliation><affiliation countryCode="IT" type="organization" xml:id="jcpe1821-aff-0002"><orgDiv>Department of Clinical Specialistic and Dental Sciences – Periodontology</orgDiv> <orgName>Polytechnic University of Marche</orgName> <address><city>Ancona</city> <country>Italy</country></address></affiliation><affiliation countryCode="IT" type="organization" xml:id="jcpe1821-aff-0003"><orgDiv>Department of Periodontology</orgDiv> <orgName>University of Florence</orgName> <address><city>Florence</city> <country>Italy</country></address></affiliation></affiliationGroup><keywordGroup type="author"><keyword xml:id="jcpe1821-kwd-0001">dental implants</keyword><keyword xml:id="jcpe1821-kwd-0002">early loaded implant</keyword><keyword xml:id="jcpe1821-kwd-0003">failures</keyword><keyword xml:id="jcpe1821-kwd-0004">flapless implant</keyword><keyword xml:id="jcpe1821-kwd-0005">immediate loaded implant</keyword><keyword xml:id="jcpe1821-kwd-0006">non‐occlusal loading</keyword><keyword xml:id="jcpe1821-kwd-0007">radiographic data</keyword><keyword xml:id="jcpe1821-kwd-0008">randomized clinical trial</keyword></keywordGroup><abstractGroup><abstract type="main" xml:id="jcpe1821-abs-0001" xml:lang="en"><title type="main">Abstract</title><section xml:id="jcpe1821-sec-0001"><title type="main">Aim</title><p>To compare immediate <i>versus</i> early non‐occlusal loading of dental implants placed flapless in a 3‐year, parallel group, randomized clinical trial.</p></section><section xml:id="jcpe1821-sec-0002"><title type="main">Materials and Methods</title><p>The study was conducted in a private dental clinic between July 2005 and July 2010. Patients 18 years or older were randomized to receive implants for fixed partial dentures in cases of partial edentulism. The test group was represented by immediate non‐occlusal implant loading, whereas the control group was represented by early non‐occlusal implant loading. The outcome variables were implant failure, complications and radiographic bone level at implant sites 3 years after loading, measured from the implant–abutment junction to the most coronal point of bone‐to‐implant contact. Randomization was computer‐generated with allocation concealment by opaque sequentially numbered sealed envelopes, and the measurer was blinded to group assignment.</p></section><section xml:id="jcpe1821-sec-0003"><title type="main">Results</title><p>Sixty patients were randomized: 30 to the immediately loaded group and 30 to the early loaded group. Four patients dropped out; however, the data of all patients were included in the analysis. No implant failure occurred. Two complications occurred in the control group and one in the test group. The mean bone level at 3 years was 1.91 mm for test group and 1.59 mm for control group. The adjusted difference in bone level was 0.26 mm (<fc>CI</fc> 95% −0.08 to 0.59, <i>p</i> = 0.1232).</p></section><section xml:id="jcpe1821-sec-0004"><title type="main">Conclusion</title><p>The null hypothesis of no difference in failure rates, complications and bone level between implants that were loaded immediately or early at 3 years cannot be rejected in this randomized clinical trial.</p></section></abstract></abstractGroup></contentMeta><noteGroup xml:id="jcpe1821-ntgp-0001"><note numbered="no" xml:id="jcpe1821-note-0001"><p><b>Conflict of interest and source of funding statement</b></p><p>Partial support for this study was provided by Thommen Medical AG, Waldenburg, Switzerland. The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.</p><p>The authors declare that there is no conflict of interest in this study.</p></note></noteGroup></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Immediate versus early non‐occlusal loading of dental implants placed flapless in partially edentulous patients: A 3‐year randomized clinical trial</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Immediate versus early non‐occlusal loading of dental implants placed flapless in partially edentulous patients: A 3‐year randomized clinical trial</title></titleInfo><name type="personal"><namePart type="given">Mauro</namePart><namePart type="family">Merli</namePart><affiliation>Private practice, Rimini, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Marco</namePart><namePart type="family">Moscatelli</namePart><affiliation>Private practice, Rimini, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Giorgia</namePart><namePart type="family">Mariotti</namePart><affiliation>Private practice, Rimini, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Matteo</namePart><namePart type="family">Piemontese</namePart><affiliation>Department of Clinical Specialistic and Dental Sciences – Periodontology, Polytechnic University of Marche, Ancona, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Michele</namePart><namePart type="family">Nieri</namePart><affiliation>Department of Periodontology, University of Florence, Florence, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><dateIssued encoding="w3cdtf">2012-02</dateIssued><dateCreated encoding="w3cdtf">2011-11-01</dateCreated><dateValid encoding="w3cdtf">2011-10-16</dateValid><copyrightDate encoding="w3cdtf">2012</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><abstract>To compare immediate versus early non‐occlusal loading of dental implants placed flapless in a 3‐year, parallel group, randomized clinical trial.</abstract><abstract>The study was conducted in a private dental clinic between July 2005 and July 2010. Patients 18 years or older were randomized to receive implants for fixed partial dentures in cases of partial edentulism. The test group was represented by immediate non‐occlusal implant loading, whereas the control group was represented by early non‐occlusal implant loading. The outcome variables were implant failure, complications and radiographic bone level at implant sites 3 years after loading, measured from the implant–abutment junction to the most coronal point of bone‐to‐implant contact. Randomization was computer‐generated with allocation concealment by opaque sequentially numbered sealed envelopes, and the measurer was blinded to group assignment.</abstract><abstract>Sixty patients were randomized: 30 to the immediately loaded group and 30 to the early loaded group. Four patients dropped out; however, the data of all patients were included in the analysis. No implant failure occurred. Two complications occurred in the control group and one in the test group. The mean bone level at 3 years was 1.91 mm for test group and 1.59 mm for control group. The adjusted difference in bone level was 0.26 mm (CI 95% −0.08 to 0.59, p = 0.1232).</abstract><abstract>The null hypothesis of no difference in failure rates, complications and bone level between implants that were loaded immediately or early at 3 years cannot be rejected in this randomized clinical trial.</abstract><subject><genre>keywords</genre><topic>dental implants</topic><topic>early loaded implant</topic><topic>failures</topic><topic>flapless implant</topic><topic>immediate loaded implant</topic><topic>non‐occlusal loading</topic><topic>radiographic data</topic><topic>randomized clinical trial</topic></subject><relatedItem type="host"><titleInfo><title>Journal of Clinical Periodontology</title></titleInfo><titleInfo type="abbreviated"><title>J Clin Periodontol</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><subject><genre>article-category</genre><topic>Implant Therapy</topic></subject><identifier type="ISSN">0303-6979</identifier><identifier type="eISSN">1600-051X</identifier><identifier type="DOI">10.1111/(ISSN)1600-051X</identifier><identifier type="PublisherID">JCPE</identifier><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>39</number></detail><detail type="issue"><caption>no.</caption><number>2</number></detail><extent unit="pages"><start>196</start><end>202</end><total>7</total></extent></part></relatedItem><identifier type="istex">69C3CA503F554C74E81B67A6423E87DB3AC17A51</identifier><identifier type="ark">ark:/67375/WNG-NBZ162DX-C</identifier><identifier type="DOI">10.1111/j.1600-051X.2011.01821.x</identifier><identifier type="ArticleID">JCPE1821</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2012 John Wiley & Sons A/S© 2011 John Wiley & Sons A/S</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-L0C46X92-X">wiley</recordContentSource></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/document/69C3CA503F554C74E81B67A6423E87DB3AC17A51/metadata/json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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