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Effects of diabetes mellitus on periodontal and peri‐implant conditions: update on associations and risks

Identifieur interne : 003220 ( Istex/Corpus ); précédent : 003219; suivant : 003221

Effects of diabetes mellitus on periodontal and peri‐implant conditions: update on associations and risks

Auteurs : Giovanni E. Salvi ; Barbara Carollo-Bittel ; Niklaus P. Lang

Source :

RBID : ISTEX:65CB7002F56DA974212F6C58171F0DAB1E8E0CA2

English descriptors

Abstract

Objectives: To review the evidence for the association between diabetes and periodontal and peri‐implant conditions and the impact of periodontal therapy in subjects with diabetes.

Url:
DOI: 10.1111/j.1600-051X.2008.01282.x

Links to Exploration step

ISTEX:65CB7002F56DA974212F6C58171F0DAB1E8E0CA2

Le document en format XML

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To review the evidence for the association between diabetes and periodontal and peri‐implant conditions and the impact of periodontal therapy in subjects with diabetes.</p>
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<hi rend="bold">Material and Methods: </hi>
A search of MEDLINE‐PubMed was performed up to and including December 2007. The search was limited to clinical studies published in English. Publications on animal studies were excluded. The selection criteria included all levels of available evidence.</p>
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Evidence on the association between diabetes and periodontitis supports the concept of increased severity but not extent of periodontitis in subjects with poorly controlled diabetes. Subjects with controlled diabetes do not show an increase in extent and severity of periodontitis. Periodontitis is associated with poor glycaemic control and diabetes‐related complications. It is inconclusive that periodontal therapy with or without the use of antibiotics results in improvements of glycaemic control and of markers of systemic inflammation. Evidence is lacking to indicate that implant therapy in subjects with diabetes yields long‐term outcomes comparable with those of non‐diabetic subjects.</p>
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Poorly controlled diabetes may be considered a risk factor for increased severity of periodontitis. The effects of periodontal therapy on glycaemic control and systemic inflammation is not proven beyond doubt and need to be confirmed in large‐scale randomized‐controlled clinical trials.</p>
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Salvi GE, Carollo-Bittel B, Lang NP. Effects of diabetes mellitus on periodontal and peri-implant conditions. Update on associations and risks. J Clin Periodontol 2008; 35 (Suppl. 8): –. doi: 10.1111/j.1600-051X.2008.01282.x.

-->
<title type="main">Abstract</title>
<p>
<b>Objectives: </b>
To review the evidence for the association between diabetes and periodontal and peri‐implant conditions and the impact of periodontal therapy in subjects with diabetes.</p>
<p>
<b>Material and Methods: </b>
A search of MEDLINE‐PubMed was performed up to and including December 2007. The search was limited to clinical studies published in English. Publications on animal studies were excluded. The selection criteria included all levels of available evidence.</p>
<p>
<b>Results: </b>
Evidence on the association between diabetes and periodontitis supports the concept of increased severity but not extent of periodontitis in subjects with poorly controlled diabetes. Subjects with controlled diabetes do not show an increase in extent and severity of periodontitis. Periodontitis is associated with poor glycaemic control and diabetes‐related complications. It is inconclusive that periodontal therapy with or without the use of antibiotics results in improvements of glycaemic control and of markers of systemic inflammation. Evidence is lacking to indicate that implant therapy in subjects with diabetes yields long‐term outcomes comparable with those of non‐diabetic subjects.</p>
<p>
<b>Conclusions: </b>
Poorly controlled diabetes may be considered a risk factor for increased severity of periodontitis. The effects of periodontal therapy on glycaemic control and systemic inflammation is not proven beyond doubt and need to be confirmed in large‐scale randomized‐controlled clinical trials.</p>
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<b>Conflict of interest and source of funding statement</b>

The authors declare that they have no conflict of interests.
This review was supported by the Clinical Research Foundation (CRF) for the Promotion of Oral Health, University of Bern, Switzerland.
The 6
<sup>th</sup>
European Workshop on Periodontology was supported by an unrestricted educational grant from Straumann AG.</p>
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