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Randomized clinical trials in implant therapy: relationships among methodological, statistical, clinical, paratextual features and number of citations

Identifieur interne : 002091 ( Istex/Corpus ); précédent : 002090; suivant : 002092

Randomized clinical trials in implant therapy: relationships among methodological, statistical, clinical, paratextual features and number of citations

Auteurs : Michele Nieri ; Carlo Clauser ; Debora Franceschi ; Umberto Pagliaro ; Daniele Saletta ; Giovanpaolo Pini-Prato

Source :

RBID : ISTEX:431D55C8B509E67AC2D3BC67BDCE662FD711D668

English descriptors

Abstract

Objectives: The aim of the present study was to investigate the relationships among reported methodological, statistical, clinical and paratextual variables of randomized clinical trials (RCTs) in implant therapy, and their influence on subsequent research.

Url:
DOI: 10.1111/j.1600-0501.2007.01350.x

Links to Exploration step

ISTEX:431D55C8B509E67AC2D3BC67BDCE662FD711D668

Le document en format XML

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<hi rend="bold">Objectives: </hi>
The aim of the present study was to investigate the relationships among reported methodological, statistical, clinical and paratextual variables of randomized clinical trials (RCTs) in implant therapy, and their influence on subsequent research.</p>
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<hi rend="bold">Materials and Methods: </hi>
The material consisted of the RCTs in implant therapy published through the end of the year 2000. Methodological, statistical, clinical and paratextual features of the articles were assessed and recorded. The perceived clinical relevance was subjectively evaluated by an experienced clinician on anonymous abstracts. The impact on research was measured by the number of citations found in the Science Citation Index. A new statistical technique (
<hi rend="italic">Structural learning of Bayesian Networks</hi>
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<hi rend="bold">Results: </hi>
Descriptive statistics revealed that the reported methodology and statistics of RCTs in implant therapy were defective. Follow‐up of the studies was generally short. The perceived clinical relevance appeared to be associated with the objectives of the studies and with the number of published images in the original articles. The impact on research was related to the nationality of the involved institutions and to the number of published images.</p>
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<hi rend="bold">Conclusions: </hi>
RCTs in implant therapy (until 2000) show important methodological and statistical flaws and may not be appropriate for guiding clinicians in their practice. The methodological and statistical quality of the studies did not appear to affect their impact on practice and research. Bayesian Networks suggest new and unexpected relationships among the methodological, statistical, clinical and paratextual features of RCTs.</p>
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Viale Matteotti, 11
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<b>Objectives: </b>
The aim of the present study was to investigate the relationships among reported methodological, statistical, clinical and paratextual variables of randomized clinical trials (RCTs) in implant therapy, and their influence on subsequent research.</p>
<p>
<b>Materials and Methods: </b>
The material consisted of the RCTs in implant therapy published through the end of the year 2000. Methodological, statistical, clinical and paratextual features of the articles were assessed and recorded. The perceived clinical relevance was subjectively evaluated by an experienced clinician on anonymous abstracts. The impact on research was measured by the number of citations found in the Science Citation Index. A new statistical technique (
<i>Structural learning of Bayesian Networks</i>
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<p>
<b>Results: </b>
Descriptive statistics revealed that the reported methodology and statistics of RCTs in implant therapy were defective. Follow‐up of the studies was generally short. The perceived clinical relevance appeared to be associated with the objectives of the studies and with the number of published images in the original articles. The impact on research was related to the nationality of the involved institutions and to the number of published images.</p>
<p>
<b>Conclusions: </b>
RCTs in implant therapy (until 2000) show important methodological and statistical flaws and may not be appropriate for guiding clinicians in their practice. The methodological and statistical quality of the studies did not appear to affect their impact on practice and research. Bayesian Networks suggest new and unexpected relationships among the methodological, statistical, clinical and paratextual features of RCTs.</p>
<!--

To cite this article:

Nieri M, Clauser C, Franceschi D, Pagliaro U, Saletta D, Pini-Prato G. Randomized clinical trials in implant therapy: relationships among methodological, statistical, clinical, paratextual features and number of citations.

Clin. Oral Impl. Res. 18, 2007; 419–431

doi: 10.1111/j.1600-0501.2007.01350.x

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<edition>Date: Accepted 9 June 2006</edition>
<copyrightDate encoding="w3cdtf">2007</copyrightDate>
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<languageTerm type="code" authority="rfc3066">en</languageTerm>
<languageTerm type="code" authority="iso639-2b">eng</languageTerm>
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<abstract>Objectives: The aim of the present study was to investigate the relationships among reported methodological, statistical, clinical and paratextual variables of randomized clinical trials (RCTs) in implant therapy, and their influence on subsequent research.</abstract>
<abstract>Materials and Methods: The material consisted of the RCTs in implant therapy published through the end of the year 2000. Methodological, statistical, clinical and paratextual features of the articles were assessed and recorded. The perceived clinical relevance was subjectively evaluated by an experienced clinician on anonymous abstracts. The impact on research was measured by the number of citations found in the Science Citation Index. A new statistical technique (Structural learning of Bayesian Networks) was used to assess the relationships among the considered variables.</abstract>
<abstract>Results: Descriptive statistics revealed that the reported methodology and statistics of RCTs in implant therapy were defective. Follow‐up of the studies was generally short. The perceived clinical relevance appeared to be associated with the objectives of the studies and with the number of published images in the original articles. The impact on research was related to the nationality of the involved institutions and to the number of published images.</abstract>
<abstract>Conclusions: RCTs in implant therapy (until 2000) show important methodological and statistical flaws and may not be appropriate for guiding clinicians in their practice. The methodological and statistical quality of the studies did not appear to affect their impact on practice and research. Bayesian Networks suggest new and unexpected relationships among the methodological, statistical, clinical and paratextual features of RCTs.</abstract>
<subject lang="en">
<genre>keywords</genre>
<topic>clinical features</topic>
<topic>dental implants</topic>
<topic>methodological features</topic>
<topic>paratextual features</topic>
<topic>randomized clinical trials</topic>
<topic>science citation index</topic>
<topic>statistical features</topic>
</subject>
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<titleInfo>
<title>Clinical Oral Implants Research</title>
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<identifier type="ISSN">0905-7161</identifier>
<identifier type="eISSN">1600-0501</identifier>
<identifier type="DOI">10.1111/(ISSN)1600-0501</identifier>
<identifier type="PublisherID">CLR</identifier>
<part>
<date>2007</date>
<detail type="volume">
<caption>vol.</caption>
<number>18</number>
</detail>
<detail type="issue">
<caption>no.</caption>
<number>4</number>
</detail>
<extent unit="pages">
<start>419</start>
<end>431</end>
<total>12</total>
</extent>
</part>
</relatedItem>
<identifier type="istex">431D55C8B509E67AC2D3BC67BDCE662FD711D668</identifier>
<identifier type="ark">ark:/67375/WNG-J791DPS5-1</identifier>
<identifier type="DOI">10.1111/j.1600-0501.2007.01350.x</identifier>
<identifier type="ArticleID">CLR1350</identifier>
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<recordOrigin>Blackwell Publishing Ltd</recordOrigin>
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