Effects of dietary gluten elimination in patients with recurrent minor aphthous stomatitis and no detectable gluten enteropathy
Identifieur interne : 001F65 ( Istex/Corpus ); précédent : 001F64; suivant : 001F66Effects of dietary gluten elimination in patients with recurrent minor aphthous stomatitis and no detectable gluten enteropathy
Auteurs : I. P. Hunter ; M. M. Ferguson ; C. Scully ; A. R. Galloway ; A. N. H. Main ; R. I. RussellSource :
- Oral Surgery, Oral Medicine, Oral Pathology [ 0030-4220 ] ; 1993.
English descriptors
- KwdEn :
- Teeft :
Abstract
Abstract: Fifty patients with a history of minor recurrent aphthous stomatitis were entered into a 6-month double-blind controlled trial of a gluten-free diet. After hematologic and biochemical investigations and jejunal biopsy, one half of the group was given a gluten-free diet; the other half served as controls and received a gluten-free diet supplemented by gluten given blind (control diet). Twenty-three patients completed the trial, 11 patients on a gluten-free diet, 12 on the control diet. Four of the 11 on the gluten-free diet and 7 of the 12 on the control diet reported significant benefit in terms of minor recurrent aphthous stomatitis, but there was no statistical difference between the responses. The results fail to support studies that report widespread benefit in aphthae of gluten withdrawal and suggest simply a marked placebo response in the condition.
Url:
DOI: 10.1016/0030-4220(93)90232-S
Links to Exploration step
ISTEX:409A5816DE162EB102031B6D523182BB2513534ALe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Effects of dietary gluten elimination in patients with recurrent minor aphthous stomatitis and no detectable gluten enteropathy</title><author><name sortKey="Hunter, I P" sort="Hunter, I P" uniqKey="Hunter I" first="I. P." last="Hunter">I. P. Hunter</name><affiliation><mods:affiliation>University Department of Oral Medicine and Oral Pathology, Dental Hospital and School, Glasgow, Scotland</mods:affiliation></affiliation></author><author><name sortKey="Ferguson, M M" sort="Ferguson, M M" uniqKey="Ferguson M" first="M. M." last="Ferguson">M. M. Ferguson</name><affiliation><mods:affiliation>University Department of Oral Medicine and Oral Pathology, Dental Hospital and School, Glasgow, Scotland</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Oral Medicine and Oral Surgery, School of Dentistry, University of Otago, Dunedin, New Zealand</mods:affiliation></affiliation></author><author><name sortKey="Scully, C" sort="Scully, C" uniqKey="Scully C" first="C." last="Scully">C. Scully</name><affiliation><mods:affiliation>Reprint requests: Professor Crispian Scully University Department of Oral Medicine, Pathology, and Microbiology Bristol Dental School and Hospital Lower Maudlin Street Bristol BS1 2LY UK</mods:affiliation></affiliation><affiliation><mods:affiliation>University Department of Oral Medicine and Oral Pathology, Dental Hospital and School, Glasgow, Scotland</mods:affiliation></affiliation><affiliation><mods:affiliation>University Department of Oral Medicine, Pathology, and Microbiology, Bristol Dental School and Hospital. Bristol, U.K.</mods:affiliation></affiliation></author><author><name sortKey="Galloway, A R" sort="Galloway, A R" uniqKey="Galloway A" first="A. R." last="Galloway">A. R. Galloway</name><affiliation><mods:affiliation>Gastroenterology Unit, Royal Infirmary, Glasgow, Scotland</mods:affiliation></affiliation></author><author><name sortKey="Main, A N H" sort="Main, A N H" uniqKey="Main A" first="A. N. H." last="Main">A. N. H. Main</name><affiliation><mods:affiliation>Gastroenterology Unit, Royal Infirmary, Glasgow, Scotland</mods:affiliation></affiliation></author><author><name sortKey="Russell, R I" sort="Russell, R I" uniqKey="Russell R" first="R. I." last="Russell">R. I. Russell</name><affiliation><mods:affiliation>Gastroenterology Unit, Royal Infirmary, Glasgow, Scotland</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:409A5816DE162EB102031B6D523182BB2513534A</idno><date when="1993" year="1993">1993</date><idno type="doi">10.1016/0030-4220(93)90232-S</idno><idno type="url">https://api.istex.fr/document/409A5816DE162EB102031B6D523182BB2513534A/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001F65</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001F65</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a">Effects of dietary gluten elimination in patients with recurrent minor aphthous stomatitis and no detectable gluten enteropathy</title><author><name sortKey="Hunter, I P" sort="Hunter, I P" uniqKey="Hunter I" first="I. P." last="Hunter">I. P. Hunter</name><affiliation><mods:affiliation>University Department of Oral Medicine and Oral Pathology, Dental Hospital and School, Glasgow, Scotland</mods:affiliation></affiliation></author><author><name sortKey="Ferguson, M M" sort="Ferguson, M M" uniqKey="Ferguson M" first="M. M." last="Ferguson">M. M. Ferguson</name><affiliation><mods:affiliation>University Department of Oral Medicine and Oral Pathology, Dental Hospital and School, Glasgow, Scotland</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Oral Medicine and Oral Surgery, School of Dentistry, University of Otago, Dunedin, New Zealand</mods:affiliation></affiliation></author><author><name sortKey="Scully, C" sort="Scully, C" uniqKey="Scully C" first="C." last="Scully">C. Scully</name><affiliation><mods:affiliation>Reprint requests: Professor Crispian Scully University Department of Oral Medicine, Pathology, and Microbiology Bristol Dental School and Hospital Lower Maudlin Street Bristol BS1 2LY UK</mods:affiliation></affiliation><affiliation><mods:affiliation>University Department of Oral Medicine and Oral Pathology, Dental Hospital and School, Glasgow, Scotland</mods:affiliation></affiliation><affiliation><mods:affiliation>University Department of Oral Medicine, Pathology, and Microbiology, Bristol Dental School and Hospital. Bristol, U.K.</mods:affiliation></affiliation></author><author><name sortKey="Galloway, A R" sort="Galloway, A R" uniqKey="Galloway A" first="A. R." last="Galloway">A. R. Galloway</name><affiliation><mods:affiliation>Gastroenterology Unit, Royal Infirmary, Glasgow, Scotland</mods:affiliation></affiliation></author><author><name sortKey="Main, A N H" sort="Main, A N H" uniqKey="Main A" first="A. N. H." last="Main">A. N. H. Main</name><affiliation><mods:affiliation>Gastroenterology Unit, Royal Infirmary, Glasgow, Scotland</mods:affiliation></affiliation></author><author><name sortKey="Russell, R I" sort="Russell, R I" uniqKey="Russell R" first="R. I." last="Russell">R. I. Russell</name><affiliation><mods:affiliation>Gastroenterology Unit, Royal Infirmary, Glasgow, Scotland</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Oral Surgery, Oral Medicine, Oral Pathology</title><title level="j" type="abbrev">OSOMOP</title><idno type="ISSN">0030-4220</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1993">1993</date><biblScope unit="volume">75</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="595">595</biblScope><biblScope unit="page" to="598">598</biblScope></imprint><idno type="ISSN">0030-4220</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0030-4220</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aphthous</term><term>Aphthous stomatitis</term><term>Control diet</term><term>Control group</term><term>Detectable gluten enteropathy</term><term>Enteropathy</term><term>Gluten</term><term>Gluten enteropathy</term><term>Gluten sensitivity</term><term>Gluten withdrawal</term><term>Jejunal</term><term>Miras</term><term>Oral medicine</term><term>Placebo</term><term>Significant difference</term><term>Stomatitis</term><term>Test group</term><term>University department</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Aphthous</term><term>Aphthous stomatitis</term><term>Control diet</term><term>Control group</term><term>Detectable gluten enteropathy</term><term>Enteropathy</term><term>Gluten</term><term>Gluten enteropathy</term><term>Gluten sensitivity</term><term>Gluten withdrawal</term><term>Jejunal</term><term>Miras</term><term>Oral medicine</term><term>Placebo</term><term>Significant difference</term><term>Stomatitis</term><term>Test group</term><term>University department</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Fifty patients with a history of minor recurrent aphthous stomatitis were entered into a 6-month double-blind controlled trial of a gluten-free diet. After hematologic and biochemical investigations and jejunal biopsy, one half of the group was given a gluten-free diet; the other half served as controls and received a gluten-free diet supplemented by gluten given blind (control diet). Twenty-three patients completed the trial, 11 patients on a gluten-free diet, 12 on the control diet. Four of the 11 on the gluten-free diet and 7 of the 12 on the control diet reported significant benefit in terms of minor recurrent aphthous stomatitis, but there was no statistical difference between the responses. The results fail to support studies that report widespread benefit in aphthae of gluten withdrawal and suggest simply a marked placebo response in the condition.</div></front></TEI><istex><corpusName>elsevier</corpusName><keywords><teeft><json:string>gluten</json:string><json:string>enteropathy</json:string><json:string>miras</json:string><json:string>placebo</json:string><json:string>gluten enteropathy</json:string><json:string>gluten withdrawal</json:string><json:string>aphthous</json:string><json:string>jejunal</json:string><json:string>control diet</json:string><json:string>stomatitis</json:string><json:string>aphthous stomatitis</json:string><json:string>control group</json:string><json:string>oral medicine</json:string><json:string>significant difference</json:string><json:string>university department</json:string><json:string>gluten sensitivity</json:string><json:string>test group</json:string><json:string>detectable gluten enteropathy</json:string></teeft></keywords><author><json:item><name>I.P. Hunter MB, BCh</name><affiliations><json:string>University Department of Oral Medicine and Oral Pathology, Dental Hospital and School, Glasgow, Scotland</json:string></affiliations></json:item><json:item><name>M.M. Ferguson MB, BCh</name><affiliations><json:string>University Department of Oral Medicine and Oral Pathology, Dental Hospital and School, Glasgow, Scotland</json:string><json:string>Department of Oral Medicine and Oral Surgery, School of Dentistry, University of Otago, Dunedin, New Zealand</json:string></affiliations></json:item><json:item><name>C. Scully MD, MDS</name><affiliations><json:string>Reprint requests: Professor Crispian Scully University Department of Oral Medicine, Pathology, and Microbiology Bristol Dental School and Hospital Lower Maudlin Street Bristol BS1 2LY UK</json:string><json:string>University Department of Oral Medicine and Oral Pathology, Dental Hospital and School, Glasgow, Scotland</json:string><json:string>University Department of Oral Medicine, Pathology, and Microbiology, Bristol Dental School and Hospital. Bristol, U.K.</json:string></affiliations></json:item><json:item><name>A.R. Galloway</name><affiliations><json:string>Gastroenterology Unit, Royal Infirmary, Glasgow, Scotland</json:string></affiliations></json:item><json:item><name>A.N.H. Main</name><affiliations><json:string>Gastroenterology Unit, Royal Infirmary, Glasgow, Scotland</json:string></affiliations></json:item><json:item><name>R.I. Russell</name><affiliations><json:string>Gastroenterology Unit, Royal Infirmary, Glasgow, Scotland</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Oral medicine</value></json:item></subject><arkIstex>ark:/67375/6H6-3BFR6PTG-L</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>Full-length article</json:string></originalGenre><abstract>Abstract: Fifty patients with a history of minor recurrent aphthous stomatitis were entered into a 6-month double-blind controlled trial of a gluten-free diet. After hematologic and biochemical investigations and jejunal biopsy, one half of the group was given a gluten-free diet; the other half served as controls and received a gluten-free diet supplemented by gluten given blind (control diet). Twenty-three patients completed the trial, 11 patients on a gluten-free diet, 12 on the control diet. Four of the 11 on the gluten-free diet and 7 of the 12 on the control diet reported significant benefit in terms of minor recurrent aphthous stomatitis, but there was no statistical difference between the responses. The results fail to support studies that report widespread benefit in aphthae of gluten withdrawal and suggest simply a marked placebo response in the condition.</abstract><qualityIndicators><score>5.393</score><pdfWordCount>1761</pdfWordCount><pdfCharCount>11286</pdfCharCount><pdfVersion>1.3</pdfVersion><pdfPageCount>4</pdfPageCount><pdfPageSize>576 x 792 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractWordCount>136</abstractWordCount><abstractCharCount>877</abstractCharCount><keywordCount>1</keywordCount></qualityIndicators><title>Effects of dietary gluten elimination in patients with recurrent minor aphthous stomatitis and no detectable gluten enteropathy</title><pmid><json:string>8488028</json:string></pmid><pii><json:string>0030-4220(93)90232-S</json:string></pii><genre><json:string>research-article</json:string></genre><host><title>Oral Surgery, Oral Medicine, Oral Pathology</title><language><json:string>unknown</json:string></language><publicationDate>1993</publicationDate><issn><json:string>0030-4220</json:string></issn><pii><json:string>S0030-4220(00)X0377-5</json:string></pii><volume>75</volume><issue>5</issue><pages><first>595</first><last>598</last></pages><genre><json:string>journal</json:string></genre></host><namedEntities><unitex><date><json:string>1993</json:string><json:string>7/13/44521</json:string></date><geogName></geogName><orgName><json:string>Dental Hospital and School</json:string><json:string>University Department of Oral Medicine, Pathology, and Microbiology, Bristol Dental School and Hospital</json:string><json:string>HOSPITAL, AND UNIVERSITY ROYAL OF OTAGO, INFIRMARY, DUNEDIN</json:string><json:string>Mosby-Year Book, Inc.</json:string></orgName><orgName_funder></orgName_funder><orgName_provider></orgName_provider><persName><json:string>C. Scully</json:string><json:string>N. H. Main</json:string><json:string>R. I. Russell</json:string><json:string>M. M. Ferguson</json:string><json:string>A. R. Galloway</json:string></persName><placeName><json:string>Dunedin</json:string><json:string>Glasgow</json:string></placeName><ref_url></ref_url><ref_bibl><json:string>Hunter et al.</json:string></ref_bibl><bibl></bibl></unitex></namedEntities><ark><json:string>ark:/67375/6H6-3BFR6PTG-L</json:string></ark><categories><wos></wos><scienceMetrix></scienceMetrix><scopus><json:string>1 - Health Sciences</json:string><json:string>2 - Dentistry</json:string><json:string>3 - General Dentistry</json:string><json:string>1 - Health Sciences</json:string><json:string>2 - Medicine</json:string><json:string>3 - Pathology and Forensic Medicine</json:string></scopus><inist><json:string>1 - sciences appliquees, technologies et medecines</json:string><json:string>2 - sciences biologiques et medicales</json:string><json:string>3 - sciences medicales</json:string></inist></categories><publicationDate>1993</publicationDate><copyrightDate>1993</copyrightDate><doi><json:string>10.1016/0030-4220(93)90232-S</json:string></doi><id>409A5816DE162EB102031B6D523182BB2513534A</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/409A5816DE162EB102031B6D523182BB2513534A/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/409A5816DE162EB102031B6D523182BB2513534A/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/409A5816DE162EB102031B6D523182BB2513534A/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a">Effects of dietary gluten elimination in patients with recurrent minor aphthous stomatitis and no detectable gluten enteropathy</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>ELSEVIER</publisher><availability><p>ELSEVIER</p></availability><date>1993</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a">Effects of dietary gluten elimination in patients with recurrent minor aphthous stomatitis and no detectable gluten enteropathy</title><author xml:id="author-0000"><persName><forename type="first">I.P.</forename><surname>Hunter</surname></persName><roleName type="degree">MB, BCh</roleName><note type="biography">FDS</note><affiliation>FDS</affiliation><affiliation>University Department of Oral Medicine and Oral Pathology, Dental Hospital and School, Glasgow, Scotland</affiliation></author><author xml:id="author-0001"><persName><forename type="first">M.M.</forename><surname>Ferguson</surname></persName><roleName type="degree">MB, BCh</roleName><note type="biography">FDS</note><affiliation>FDS</affiliation><affiliation>University Department of Oral Medicine and Oral Pathology, Dental Hospital and School, Glasgow, Scotland</affiliation><affiliation>Department of Oral Medicine and Oral Surgery, School of Dentistry, University of Otago, Dunedin, New Zealand</affiliation></author><author xml:id="author-0002"><persName><forename type="first">C.</forename><surname>Scully</surname></persName><roleName type="degree">MD, MDS</roleName><note type="biography">FDJ, FRCPath</note><affiliation>FDJ, FRCPath</affiliation><affiliation>Reprint requests: Professor Crispian Scully University Department of Oral Medicine, Pathology, and Microbiology Bristol Dental School and Hospital Lower Maudlin Street Bristol BS1 2LY UK</affiliation><affiliation>University Department of Oral Medicine and Oral Pathology, Dental Hospital and School, Glasgow, Scotland</affiliation><affiliation>University Department of Oral Medicine, Pathology, and Microbiology, Bristol Dental School and Hospital. Bristol, U.K.</affiliation></author><author xml:id="author-0003"><persName><forename type="first">A.R.</forename><surname>Galloway</surname></persName><note type="biography">MRCP</note><affiliation>MRCP</affiliation><affiliation>Gastroenterology Unit, Royal Infirmary, Glasgow, Scotland</affiliation></author><author xml:id="author-0004"><persName><forename type="first">A.N.H.</forename><surname>Main</surname></persName><note type="biography">MRCP</note><affiliation>MRCP</affiliation><affiliation>Gastroenterology Unit, Royal Infirmary, Glasgow, Scotland</affiliation></author><author xml:id="author-0005"><persName><forename type="first">R.I.</forename><surname>Russell</surname></persName><note type="biography">FRCP</note><affiliation>FRCP</affiliation><affiliation>Gastroenterology Unit, Royal Infirmary, Glasgow, Scotland</affiliation></author><idno type="istex">409A5816DE162EB102031B6D523182BB2513534A</idno><idno type="DOI">10.1016/0030-4220(93)90232-S</idno><idno type="PII">0030-4220(93)90232-S</idno></analytic><monogr><title level="j">Oral Surgery, Oral Medicine, Oral Pathology</title><title level="j" type="abbrev">OSOMOP</title><idno type="pISSN">0030-4220</idno><idno type="PII">S0030-4220(00)X0377-5</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1993"></date><biblScope unit="volume">75</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="595">595</biblScope><biblScope unit="page" to="598">598</biblScope></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1993</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Fifty patients with a history of minor recurrent aphthous stomatitis were entered into a 6-month double-blind controlled trial of a gluten-free diet. After hematologic and biochemical investigations and jejunal biopsy, one half of the group was given a gluten-free diet; the other half served as controls and received a gluten-free diet supplemented by gluten given blind (control diet). Twenty-three patients completed the trial, 11 patients on a gluten-free diet, 12 on the control diet. Four of the 11 on the gluten-free diet and 7 of the 12 on the control diet reported significant benefit in terms of minor recurrent aphthous stomatitis, but there was no statistical difference between the responses. The results fail to support studies that report widespread benefit in aphthae of gluten withdrawal and suggest simply a marked placebo response in the condition.</p></abstract><textClass><keywords scheme="keyword"><list><head>article-category</head><item><term>Oral medicine</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="1993">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/409A5816DE162EB102031B6D523182BB2513534A/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier, elements deleted: tail"><istex:xmlDeclaration>version="1.0" encoding="utf-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 4.5.2//EN//XML" URI="art452.dtd" name="istex:docType"></istex:docType><istex:document><converted-article version="4.5.2" docsubtype="fla"><item-info><jid>OSOMOP</jid><aid>9390232S</aid><ce:pii>0030-4220(93)90232-S</ce:pii><ce:doi>10.1016/0030-4220(93)90232-S</ce:doi><ce:copyright type="unknown" year="1993"></ce:copyright><ce:doctopics><ce:doctopic><ce:text>Oral medicine</ce:text></ce:doctopic></ce:doctopics></item-info><head><ce:title>Effects of dietary gluten elimination in patients with recurrent minor aphthous stomatitis and no detectable gluten enteropathy</ce:title><ce:author-group><ce:author><ce:given-name>I.P.</ce:given-name><ce:surname>Hunter</ce:surname><ce:degrees>MB, BCh</ce:degrees><ce:roles>FDS</ce:roles><ce:cross-ref refid="AFF1"><ce:sup>a</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>M.M.</ce:given-name><ce:surname>Ferguson</ce:surname><ce:degrees>MB, BCh</ce:degrees><ce:roles>FDS</ce:roles><ce:cross-ref refid="AFF1"><ce:sup>a</ce:sup></ce:cross-ref><ce:cross-ref refid="AFF2"><ce:sup>b</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>C.</ce:given-name><ce:surname>Scully</ce:surname><ce:degrees>MD, MDS</ce:degrees><ce:roles>FDJ, FRCPath</ce:roles><ce:cross-ref refid="COR1"><ce:sup>1</ce:sup></ce:cross-ref><ce:cross-ref refid="AFF1"><ce:sup>a</ce:sup></ce:cross-ref><ce:cross-ref refid="AFF3"><ce:sup>c</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>A.R.</ce:given-name><ce:surname>Galloway</ce:surname><ce:roles>MRCP</ce:roles><ce:cross-ref refid="AFF4"><ce:sup>d</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>A.N.H.</ce:given-name><ce:surname>Main</ce:surname><ce:roles>MRCP</ce:roles><ce:cross-ref refid="AFF4"><ce:sup>d</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>R.I.</ce:given-name><ce:surname>Russell</ce:surname><ce:roles>FRCP</ce:roles><ce:cross-ref refid="AFF4"><ce:sup>d</ce:sup></ce:cross-ref></ce:author><ce:affiliation id="AFF1"><ce:label>a</ce:label><ce:textfn>University Department of Oral Medicine and Oral Pathology, Dental Hospital and School, Glasgow, Scotland</ce:textfn></ce:affiliation><ce:affiliation id="AFF2"><ce:label>b</ce:label><ce:textfn>Department of Oral Medicine and Oral Surgery, School of Dentistry, University of Otago, Dunedin, New Zealand</ce:textfn></ce:affiliation><ce:affiliation id="AFF3"><ce:label>c</ce:label><ce:textfn>University Department of Oral Medicine, Pathology, and Microbiology, Bristol Dental School and Hospital. Bristol, U.K.</ce:textfn></ce:affiliation><ce:affiliation id="AFF4"><ce:label>d</ce:label><ce:textfn>Gastroenterology Unit, Royal Infirmary, Glasgow, Scotland</ce:textfn></ce:affiliation><ce:correspondence id="COR1"><ce:label>1</ce:label><ce:text><ce:italic>Reprint requests:</ce:italic> Professor Crispian Scully University Department of Oral Medicine, Pathology, and Microbiology Bristol Dental School and Hospital Lower Maudlin Street Bristol BS1 2LY UK</ce:text></ce:correspondence></ce:author-group><ce:abstract><ce:section-title>Abstract</ce:section-title><ce:abstract-sec><ce:simple-para>Fifty patients with a history of minor recurrent aphthous stomatitis were entered into a 6-month double-blind controlled trial of a gluten-free diet. After hematologic and biochemical investigations and jejunal biopsy, one half of the group was given a gluten-free diet; the other half served as controls and received a gluten-free diet supplemented by gluten given blind (control diet). Twenty-three patients completed the trial, 11 patients on a gluten-free diet, 12 on the control diet. Four of the 11 on the gluten-free diet and 7 of the 12 on the control diet reported significant benefit in terms of minor recurrent aphthous stomatitis, but there was no statistical difference between the responses. The results fail to support studies that report widespread benefit in aphthae of gluten withdrawal and suggest simply a marked placebo response in the condition.</ce:simple-para></ce:abstract-sec></ce:abstract></head></converted-article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo><title>Effects of dietary gluten elimination in patients with recurrent minor aphthous stomatitis and no detectable gluten enteropathy</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Effects of dietary gluten elimination in patients with recurrent minor aphthous stomatitis and no detectable gluten enteropathy</title></titleInfo><name type="personal"><namePart type="given">I.P.</namePart><namePart type="family">Hunter</namePart><namePart type="termsOfAddress">MB, BCh</namePart><affiliation>University Department of Oral Medicine and Oral Pathology, Dental Hospital and School, Glasgow, Scotland</affiliation><description>FDS</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.M.</namePart><namePart type="family">Ferguson</namePart><namePart type="termsOfAddress">MB, BCh</namePart><affiliation>University Department of Oral Medicine and Oral Pathology, Dental Hospital and School, Glasgow, Scotland</affiliation><affiliation>Department of Oral Medicine and Oral Surgery, School of Dentistry, University of Otago, Dunedin, New Zealand</affiliation><description>FDS</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C.</namePart><namePart type="family">Scully</namePart><namePart type="termsOfAddress">MD, MDS</namePart><affiliation>Reprint requests: Professor Crispian Scully University Department of Oral Medicine, Pathology, and Microbiology Bristol Dental School and Hospital Lower Maudlin Street Bristol BS1 2LY UK</affiliation><affiliation>University Department of Oral Medicine and Oral Pathology, Dental Hospital and School, Glasgow, Scotland</affiliation><affiliation>University Department of Oral Medicine, Pathology, and Microbiology, Bristol Dental School and Hospital. Bristol, U.K.</affiliation><description>FDJ, FRCPath</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A.R.</namePart><namePart type="family">Galloway</namePart><affiliation>Gastroenterology Unit, Royal Infirmary, Glasgow, Scotland</affiliation><description>MRCP</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A.N.H.</namePart><namePart type="family">Main</namePart><affiliation>Gastroenterology Unit, Royal Infirmary, Glasgow, Scotland</affiliation><description>MRCP</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R.I.</namePart><namePart type="family">Russell</namePart><affiliation>Gastroenterology Unit, Royal Infirmary, Glasgow, Scotland</affiliation><description>FRCP</description><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="Full-length article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1993</dateIssued><copyrightDate encoding="w3cdtf">1993</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><abstract lang="en">Abstract: Fifty patients with a history of minor recurrent aphthous stomatitis were entered into a 6-month double-blind controlled trial of a gluten-free diet. After hematologic and biochemical investigations and jejunal biopsy, one half of the group was given a gluten-free diet; the other half served as controls and received a gluten-free diet supplemented by gluten given blind (control diet). Twenty-three patients completed the trial, 11 patients on a gluten-free diet, 12 on the control diet. Four of the 11 on the gluten-free diet and 7 of the 12 on the control diet reported significant benefit in terms of minor recurrent aphthous stomatitis, but there was no statistical difference between the responses. The results fail to support studies that report widespread benefit in aphthae of gluten withdrawal and suggest simply a marked placebo response in the condition.</abstract><subject><genre>article-category</genre><topic>Oral medicine</topic></subject><relatedItem type="host"><titleInfo><title>Oral Surgery, Oral Medicine, Oral Pathology</title></titleInfo><titleInfo type="abbreviated"><title>OSOMOP</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">199305</dateIssued></originInfo><identifier type="ISSN">0030-4220</identifier><identifier type="PII">S0030-4220(00)X0377-5</identifier><part><date>199305</date><detail type="volume"><number>75</number><caption>vol.</caption></detail><detail type="issue"><number>5</number><caption>no.</caption></detail><extent unit="issue-pages"><start>A11</start><end>A12</end></extent><extent unit="issue-pages"><start>A2</start><end>A10</end></extent><extent unit="issue-pages"><start>539</start><end>662</end></extent><extent unit="pages"><start>595</start><end>598</end></extent></part></relatedItem><identifier type="istex">409A5816DE162EB102031B6D523182BB2513534A</identifier><identifier type="ark">ark:/67375/6H6-3BFR6PTG-L</identifier><identifier type="DOI">10.1016/0030-4220(93)90232-S</identifier><identifier type="PII">0030-4220(93)90232-S</identifier><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-HKKZVM7B-M">elsevier</recordContentSource></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/document/409A5816DE162EB102031B6D523182BB2513534A/metadata/json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001F65 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 001F65 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= EdenteV2
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:409A5816DE162EB102031B6D523182BB2513534A
|texte= Effects of dietary gluten elimination in patients with recurrent minor aphthous stomatitis and no detectable gluten enteropathy
}}
| This area was generated with Dilib version V0.6.32. |  |