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Fibrin Clot Extension on Zirconia Surface for Dental Implants: A Quantitative In Vitro Study

Identifieur interne : 001E46 ( Istex/Corpus ); précédent : 001E45; suivant : 001E47

Fibrin Clot Extension on Zirconia Surface for Dental Implants: A Quantitative In Vitro Study

Auteurs : Tonino Traini ; Sergio Caputi ; Enrico Gherlone ; Marco Degidi ; Adriano Piattelli

Source :

RBID : ISTEX:3E1F5444EE6FD5A4DCC20D3F1414152F960AA544

Abstract

The surface chemical and physical properties of materials used for implants have a major influence on blood clot organization. This study aims to evaluate the blood clot extension (bce) on zirconia and titanium. bce was measured in association to surface roughness (Ra) and static contact angle (θ).

Url:
DOI: 10.1111/cid.12038

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ISTEX:3E1F5444EE6FD5A4DCC20D3F1414152F960AA544

Le document en format XML

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<affiliation>Reprint requests: Dr. Tonino Traini, Department of Dentistry, Vita Salute University, San Raffaele Hospital, via Olgettina 58, 20132 Milano, Italy; e‐mail t.traini@gmail.com</affiliation>
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<abstract style="main">
<head>Abstract</head>
Purpose
<p>The surface chemical and physical properties of materials used for implants have a major influence on blood clot organization. This study aims to evaluate the blood clot extension (
<hi rend="italic">bce</hi>
) on zirconia and titanium.
<hi rend="italic">bce</hi>
was measured in association to surface roughness (
<hi rend="italic">
<hi rend="fc">R</hi>
a</hi>
) and static contact angle (θ).</p>
Materials and Methods
<p>Forty disk‐shaped samples of sandblasted yttria tetragonal zirconia polycrystal (
<hi rend="italic">sb‐
<hi rend="fc">YTZP</hi>
</hi>
), machined titanium (
<hi rend="italic">m‐
<hi rend="fc">T</hi>
i</hi>
), and sandblasted, high‐temperature, acid‐etched titanium (
<hi rend="italic">p‐
<hi rend="fc">T</hi>
i</hi>
) were used in the present study. About 0.2 mL of human blood, immediately dropped onto the specimen's surface and left in contact for 5 minutes at room temperature, was used to measure the
<hi rend="italic">bce</hi>
. Specimens were observed under confocal scanning laser and scanning electron microscopes.</p>
Results
<p>The
<hi rend="italic">bce</hi>
(mean × 10
<hi rend="superscript">7</hi>
 ± standard deviation [
<hi rend="fc">SD</hi>
] × 10
<hi rend="superscript">6</hi>
 μm
<hi rend="superscript">2</hi>
) was 2.97 ± 6.68 for
<hi rend="italic">m‐
<hi rend="fc">T</hi>
i</hi>
, 5.64 ± 6.83 for
<hi rend="italic">p‐
<hi rend="fc">T</hi>
i</hi>
, and 3.61 ± 7.67 for
<hi rend="italic">sb‐
<hi rend="fc">YTZP</hi>
</hi>
.
<hi rend="italic">p‐
<hi rend="fc">T</hi>
i</hi>
samples showed a significantly higher
<hi rend="italic">bce</hi>
.
<hi rend="italic">
<hi rend="fc">R</hi>
a</hi>
(mean ± 
<hi rend="fc">SD</hi>
[μm]) was 0.56 ± 0.7 for
<hi rend="italic">m‐
<hi rend="fc">T</hi>
i,</hi>
3.78 ± 0.8 for
<hi rend="italic">p‐
<hi rend="fc">T</hi>
i</hi>
, and 2.68 ± 0.6 for
<hi rend="italic">sb‐
<hi rend="fc">YTZP</hi>
.</hi>
The difference was not significant between
<hi rend="italic">sb‐
<hi rend="fc">YTZP</hi>
</hi>
and
<hi rend="italic">p‐
<hi rend="fc">T</hi>
i</hi>
. θ (mean ± 
<hi rend="fc">SD</hi>
) was 55.6 ± 5.6 for
<hi rend="italic">m‐
<hi rend="fc">T</hi>
i</hi>
, 48.7 ± 2.8 for
<hi rend="italic">sb‐
<hi rend="fc">YTZP</hi>
</hi>
, and 38.0 ± 2.2 for
<hi rend="italic">p‐
<hi rend="fc">T</hi>
i</hi>
. The difference was not significant between
<hi rend="italic">m‐
<hi rend="fc">T</hi>
i</hi>
and
<hi rend="italic">sb‐
<hi rend="fc">YTZP</hi>
</hi>
.</p>
Conclusions
<p>The
<hi rend="italic">sb‐
<hi rend="fc">YTZP</hi>
</hi>
demonstrated a significantly lesser amount of
<hi rend="italic">bce</hi>
compared with
<hi rend="italic">p‐
<hi rend="fc">T</hi>
i</hi>
specimens, notwithstanding that any significant difference was present between
<hi rend="italic">
<hi rend="fc">R</hi>
a</hi>
and θ.</p>
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<numbering type="pageFirst">718</numbering>
<numbering type="pageLast">727</numbering>
</numberingGroup>
<correspondenceTo>Reprint requests: Dr. Tonino Traini, Department of Dentistry, Vita Salute University, San Raffaele Hospital, via Olgettina 58, 20132 Milano, Italy; e‐mail
<email>t.traini@gmail.com</email>
</correspondenceTo>
<linkGroup>
<link type="toTypesetVersion" href="file://CID.CID12038.pdf"></link>
</linkGroup>
</publicationMeta>
<contentMeta>
<titleGroup>
<title type="short">Evaluation of Fibrin Clot Extension on Zirconia</title>
<title type="main">Fibrin Clot Extension on Zirconia Surface for Dental Implants: A Quantitative In Vitro Study</title>
</titleGroup>
<creators>
<creator affiliationRef="#cid12038-aff-0001 #cid12038-aff-0002" corresponding="yes" creatorRole="author" xml:id="cid12038-cr-0001">
<personName>
<givenNames>Tonino</givenNames>
<familyName>Traini</familyName>
<degrees>DDS, PhD</degrees>
</personName>
</creator>
<creator affiliationRef="#cid12038-aff-0001" creatorRole="author" xml:id="cid12038-cr-0002">
<personName>
<givenNames>Sergio</givenNames>
<familyName>Caputi</familyName>
<degrees>MD, DDS</degrees>
</personName>
</creator>
<creator affiliationRef="#cid12038-aff-0002" creatorRole="author" xml:id="cid12038-cr-0003">
<personName>
<givenNames>Enrico</givenNames>
<familyName>Gherlone</familyName>
<degrees>MD, DDS</degrees>
</personName>
</creator>
<creator affiliationRef="#cid12038-aff-5001" creatorRole="author" xml:id="cid12038-cr-0004">
<personName>
<givenNames>Marco</givenNames>
<familyName>Degidi</familyName>
<degrees>MD, DDS</degrees>
</personName>
</creator>
<creator affiliationRef="#cid12038-aff-0001" creatorRole="author" xml:id="cid12038-cr-0005">
<personName>
<givenNames>Adriano</givenNames>
<familyName>Piattelli</familyName>
<degrees>MD, DDS</degrees>
</personName>
</creator>
</creators>
<affiliationGroup>
<affiliation countryCode="IT" xml:id="cid12038-aff-0001">
<orgDiv>Department of Medical, Oral and Biotechnological Sciences</orgDiv>
<orgName>University of Chieti‐Pescara</orgName>
<address>
<city>Chieti‐Pescara</city>
<country>Italy</country>
</address>
</affiliation>
<affiliation countryCode="IT" xml:id="cid12038-aff-0002">
<orgDiv>Department of Dentistry</orgDiv>
<orgDiv>San Raffaele Hospital</orgDiv>
<orgName>Vita Salute University</orgName>
<address>
<city>Milano</city>
<country>Italy</country>
</address>
</affiliation>
<affiliation countryCode="IT" xml:id="cid12038-aff-5001">
<orgName>private practice</orgName>
<address>
<city>Bologna</city>
<country>Italy</country>
</address>
</affiliation>
</affiliationGroup>
<keywordGroup type="author">
<keyword xml:id="cid12038-kwd-0001">blood–material interaction</keyword>
<keyword xml:id="cid12038-kwd-0002">dental/endosteal implant</keyword>
<keyword xml:id="cid12038-kwd-0003">fibrin</keyword>
<keyword xml:id="cid12038-kwd-0004">surface characterization</keyword>
</keywordGroup>
<abstractGroup>
<abstract type="main">
<title type="main">Abstract</title>
<section xml:id="cid12038-sec-0001">
<title type="main">Purpose</title>
<p>The surface chemical and physical properties of materials used for implants have a major influence on blood clot organization. This study aims to evaluate the blood clot extension (
<i>bce</i>
) on zirconia and titanium.
<i>bce</i>
was measured in association to surface roughness (
<i>
<fc>R</fc>
a</i>
) and static contact angle (θ).</p>
</section>
<section xml:id="cid12038-sec-0002">
<title type="main">Materials and Methods</title>
<p>Forty disk‐shaped samples of sandblasted yttria tetragonal zirconia polycrystal (
<i>sb‐
<fc>YTZP</fc>
</i>
), machined titanium (
<i>m‐
<fc>T</fc>
i</i>
), and sandblasted, high‐temperature, acid‐etched titanium (
<i>p‐
<fc>T</fc>
i</i>
) were used in the present study. About 0.2 mL of human blood, immediately dropped onto the specimen's surface and left in contact for 5 minutes at room temperature, was used to measure the
<i>bce</i>
. Specimens were observed under confocal scanning laser and scanning electron microscopes.</p>
</section>
<section xml:id="cid12038-sec-0003">
<title type="main">Results</title>
<p>The
<i>bce</i>
(mean × 10
<sup>7</sup>
 ± standard deviation [
<fc>SD</fc>
] × 10
<sup>6</sup>
 μm
<sup>2</sup>
) was 2.97 ± 6.68 for
<i>m‐
<fc>T</fc>
i</i>
, 5.64 ± 6.83 for
<i>p‐
<fc>T</fc>
i</i>
, and 3.61 ± 7.67 for
<i>sb‐
<fc>YTZP</fc>
</i>
.
<i>p‐
<fc>T</fc>
i</i>
samples showed a significantly higher
<i>bce</i>
.
<i>
<fc>R</fc>
a</i>
(mean ± 
<fc>SD</fc>
[μm]) was 0.56 ± 0.7 for
<i>m‐
<fc>T</fc>
i,</i>
3.78 ± 0.8 for
<i>p‐
<fc>T</fc>
i</i>
, and 2.68 ± 0.6 for
<i>sb‐
<fc>YTZP</fc>
.</i>
The difference was not significant between
<i>sb‐
<fc>YTZP</fc>
</i>
and
<i>p‐
<fc>T</fc>
i</i>
. θ (mean ± 
<fc>SD</fc>
) was 55.6 ± 5.6 for
<i>m‐
<fc>T</fc>
i</i>
, 48.7 ± 2.8 for
<i>sb‐
<fc>YTZP</fc>
</i>
, and 38.0 ± 2.2 for
<i>p‐
<fc>T</fc>
i</i>
. The difference was not significant between
<i>m‐
<fc>T</fc>
i</i>
and
<i>sb‐
<fc>YTZP</fc>
</i>
.</p>
</section>
<section xml:id="cid12038-sec-0004">
<title type="main">Conclusions</title>
<p>The
<i>sb‐
<fc>YTZP</fc>
</i>
demonstrated a significantly lesser amount of
<i>bce</i>
compared with
<i>p‐
<fc>T</fc>
i</i>
specimens, notwithstanding that any significant difference was present between
<i>
<fc>R</fc>
a</i>
and θ.</p>
</section>
</abstract>
</abstractGroup>
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<title>Fibrin Clot Extension on Zirconia Surface for Dental Implants: A Quantitative In Vitro Study</title>
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<title>Evaluation of Fibrin Clot Extension on Zirconia</title>
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<title>Fibrin Clot Extension on Zirconia Surface for Dental Implants: A Quantitative In Vitro Study</title>
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<affiliation>Department of Medical, Oral and Biotechnological Sciences, University of Chieti‐Pescara, Chieti‐Pescara, Italy</affiliation>
<affiliation>Department of Dentistry, San Raffaele Hospital, Vita Salute University, Milano, Italy</affiliation>
<affiliation>E-mail: t.traini@gmail.com</affiliation>
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<namePart type="family">Caputi</namePart>
<namePart type="termsOfAddress">MD, DDS</namePart>
<affiliation>Department of Medical, Oral and Biotechnological Sciences, University of Chieti‐Pescara, Chieti‐Pescara, Italy</affiliation>
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<name type="personal">
<namePart type="given">Enrico</namePart>
<namePart type="family">Gherlone</namePart>
<namePart type="termsOfAddress">MD, DDS</namePart>
<affiliation>Department of Dentistry, San Raffaele Hospital, Vita Salute University, Milano, Italy</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
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</name>
<name type="personal">
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<namePart type="family">Degidi</namePart>
<namePart type="termsOfAddress">MD, DDS</namePart>
<affiliation>private practice, Bologna, Italy</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Adriano</namePart>
<namePart type="family">Piattelli</namePart>
<namePart type="termsOfAddress">MD, DDS</namePart>
<affiliation>Department of Medical, Oral and Biotechnological Sciences, University of Chieti‐Pescara, Chieti‐Pescara, Italy</affiliation>
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<languageTerm type="code" authority="iso639-2b">eng</languageTerm>
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<abstract>The surface chemical and physical properties of materials used for implants have a major influence on blood clot organization. This study aims to evaluate the blood clot extension (bce) on zirconia and titanium. bce was measured in association to surface roughness (Ra) and static contact angle (θ).</abstract>
<abstract>Forty disk‐shaped samples of sandblasted yttria tetragonal zirconia polycrystal (sb‐YTZP), machined titanium (m‐Ti), and sandblasted, high‐temperature, acid‐etched titanium (p‐Ti) were used in the present study. About 0.2 mL of human blood, immediately dropped onto the specimen's surface and left in contact for 5 minutes at room temperature, was used to measure the bce. Specimens were observed under confocal scanning laser and scanning electron microscopes.</abstract>
<abstract>The bce (mean × 107 ± standard deviation [SD] × 106 μm2) was 2.97 ± 6.68 for m‐Ti, 5.64 ± 6.83 for p‐Ti, and 3.61 ± 7.67 for sb‐YTZP. p‐Ti samples showed a significantly higher bce. Ra (mean ± SD [μm]) was 0.56 ± 0.7 for m‐Ti, 3.78 ± 0.8 for p‐Ti, and 2.68 ± 0.6 for sb‐YTZP. The difference was not significant between sb‐YTZP and p‐Ti. θ (mean ± SD) was 55.6 ± 5.6 for m‐Ti, 48.7 ± 2.8 for sb‐YTZP, and 38.0 ± 2.2 for p‐Ti. The difference was not significant between m‐Ti and sb‐YTZP.</abstract>
<abstract>The sb‐YTZP demonstrated a significantly lesser amount of bce compared with p‐Ti specimens, notwithstanding that any significant difference was present between Ra and θ.</abstract>
<subject>
<genre>keywords</genre>
<topic>blood–material interaction</topic>
<topic>dental/endosteal implant</topic>
<topic>fibrin</topic>
<topic>surface characterization</topic>
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<title>Clinical Implant Dentistry and Related Research</title>
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<title>Clinical Implant Dentistry and Related Research</title>
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<identifier type="ISSN">1523-0899</identifier>
<identifier type="eISSN">1708-8208</identifier>
<identifier type="DOI">10.1111/(ISSN)1708-8208</identifier>
<identifier type="PublisherID">CID</identifier>
<part>
<date>2014</date>
<detail type="volume">
<caption>vol.</caption>
<number>16</number>
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<caption>no.</caption>
<number>5</number>
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<accessCondition type="use and reproduction" contentType="copyright">Copyright © 2014 Wiley Periodicals, Inc.© 2013 Wiley Periodicals, Inc.</accessCondition>
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