Papillon‐Lefèvre Syndrome in Four Siblings Treated with Etretinate A Nine‐Year Evaluation
Identifieur interne : 001C68 ( Istex/Corpus ); précédent : 001C67; suivant : 001C69Papillon‐Lefèvre Syndrome in Four Siblings Treated with Etretinate A Nine‐Year Evaluation
Auteurs : Robert E. KellumSource :
- International Journal of Dermatology [ 0011-9059 ] ; 1989-11.
English descriptors
- KwdEn :
- American nchs charts, August, Average dose, Baseline laboratory evaluation, Bright erythema, Dorsal feet, Dorsal surfaces, Epiphyseal lines, Etretinate, Etretinate therapy, Familial cases, Fasting triglycerides, First diagnosis, First time, Hair loss, Hyperkeratosis, Hyperkeratosis palmoplantaris, Hyperkeratotic, Inflammatory gingivai disease, Keratosis palmoplantaris, Keratotic plaques, King faisal specialist hospital, Last visit, Ligamentous calcification, Month intervals, Normal limits, November, Periodontosis syndrome, Permanent teeth, Plantar, Plantar feet, Plantar hyperkeratosis, Pretibial areas, Research centre, Saudi arabia, Serum immunoglobulins, Serum protein electrophoresis, Serum triglycerides, Sibling, Skeletal survey, Syndrome, Triglyceride.
- Teeft :
- American nchs charts, August, Average dose, Baseline laboratory evaluation, Bright erythema, Dorsal feet, Dorsal surfaces, Epiphyseal lines, Etretinate, Etretinate therapy, Familial cases, Fasting triglycerides, First diagnosis, First time, Hair loss, Hyperkeratosis, Hyperkeratosis palmoplantaris, Hyperkeratotic, Inflammatory gingivai disease, Keratosis palmoplantaris, Keratotic plaques, King faisal specialist hospital, Last visit, Ligamentous calcification, Month intervals, Normal limits, November, Periodontosis syndrome, Permanent teeth, Plantar, Plantar feet, Plantar hyperkeratosis, Pretibial areas, Research centre, Saudi arabia, Serum immunoglobulins, Serum protein electrophoresis, Serum triglycerides, Sibling, Skeletal survey, Syndrome, Triglyceride.
Abstract
Four siblings with Papillon‐Lefèvre syndrome (3 boys and 1 girl), aged 8 to 12 at time of first diagnosis in 1978 are reported. These four patients represent the second largest sibship reported in the literature, and the only familial cases treated with etretinate for 6 years with an additional 3 1/2 year follow‐up evaluation. No long‐term side effects of etretinate were found in the children. All four patients are the product of a second cousin marriage; all demonstrate the B5 locus on HLA typing.
Url:
DOI: 10.1111/j.1365-4362.1989.tb02539.x
Links to Exploration step
ISTEX:3A990110DBFD646FA0D40990A5A357EE70CF8EC0Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Papillon‐Lefèvre Syndrome in Four Siblings Treated with Etretinate A Nine‐Year Evaluation</title><author><name sortKey="Kellum, Robert E" sort="Kellum, Robert E" uniqKey="Kellum R" first="Robert E." last="Kellum">Robert E. Kellum</name><affiliation><mods:affiliation>From the Department of Medicine, King Faisal Specialist Hospital and Research Centre Riyadh, Saudi Arabia</mods:affiliation></affiliation><affiliation><mods:affiliation>Correspondence address: Address for correspondence: Robert E. Kellum, M.D., Department of Medicine, King Faisal Specialist Hospital and Research Centre, P. O. Box 3354, Riyadh 11211, Saudi Arabia.</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:3A990110DBFD646FA0D40990A5A357EE70CF8EC0</idno><date when="1989" year="1989">1989</date><idno type="doi">10.1111/j.1365-4362.1989.tb02539.x</idno><idno type="url">https://api.istex.fr/document/3A990110DBFD646FA0D40990A5A357EE70CF8EC0/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001C68</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001C68</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Papillon‐Lefèvre Syndrome in Four Siblings Treated with Etretinate A Nine‐Year Evaluation</title><author><name sortKey="Kellum, Robert E" sort="Kellum, Robert E" uniqKey="Kellum R" first="Robert E." last="Kellum">Robert E. Kellum</name><affiliation><mods:affiliation>From the Department of Medicine, King Faisal Specialist Hospital and Research Centre Riyadh, Saudi Arabia</mods:affiliation></affiliation><affiliation><mods:affiliation>Correspondence address: Address for correspondence: Robert E. Kellum, M.D., Department of Medicine, King Faisal Specialist Hospital and Research Centre, P. O. Box 3354, Riyadh 11211, Saudi Arabia.</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">International Journal of Dermatology</title><title level="j" type="alt">INTERNATIONAL JOURNAL OF DERMATOLOGY</title><idno type="ISSN">0011-9059</idno><idno type="eISSN">1365-4632</idno><imprint><biblScope unit="vol">28</biblScope><biblScope unit="issue">9</biblScope><biblScope unit="page" from="605">605</biblScope><biblScope unit="page" to="608">608</biblScope><biblScope unit="page-count">4</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="1989-11">1989-11</date></imprint><idno type="ISSN">0011-9059</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0011-9059</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>American nchs charts</term><term>August</term><term>Average dose</term><term>Baseline laboratory evaluation</term><term>Bright erythema</term><term>Dorsal feet</term><term>Dorsal surfaces</term><term>Epiphyseal lines</term><term>Etretinate</term><term>Etretinate therapy</term><term>Familial cases</term><term>Fasting triglycerides</term><term>First diagnosis</term><term>First time</term><term>Hair loss</term><term>Hyperkeratosis</term><term>Hyperkeratosis palmoplantaris</term><term>Hyperkeratotic</term><term>Inflammatory gingivai disease</term><term>Keratosis palmoplantaris</term><term>Keratotic plaques</term><term>King faisal specialist hospital</term><term>Last visit</term><term>Ligamentous calcification</term><term>Month intervals</term><term>Normal limits</term><term>November</term><term>Periodontosis syndrome</term><term>Permanent teeth</term><term>Plantar</term><term>Plantar feet</term><term>Plantar hyperkeratosis</term><term>Pretibial areas</term><term>Research centre</term><term>Saudi arabia</term><term>Serum immunoglobulins</term><term>Serum protein electrophoresis</term><term>Serum triglycerides</term><term>Sibling</term><term>Skeletal survey</term><term>Syndrome</term><term>Triglyceride</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>American nchs charts</term><term>August</term><term>Average dose</term><term>Baseline laboratory evaluation</term><term>Bright erythema</term><term>Dorsal feet</term><term>Dorsal surfaces</term><term>Epiphyseal lines</term><term>Etretinate</term><term>Etretinate therapy</term><term>Familial cases</term><term>Fasting triglycerides</term><term>First diagnosis</term><term>First time</term><term>Hair loss</term><term>Hyperkeratosis</term><term>Hyperkeratosis palmoplantaris</term><term>Hyperkeratotic</term><term>Inflammatory gingivai disease</term><term>Keratosis palmoplantaris</term><term>Keratotic plaques</term><term>King faisal specialist hospital</term><term>Last visit</term><term>Ligamentous calcification</term><term>Month intervals</term><term>Normal limits</term><term>November</term><term>Periodontosis syndrome</term><term>Permanent teeth</term><term>Plantar</term><term>Plantar feet</term><term>Plantar hyperkeratosis</term><term>Pretibial areas</term><term>Research centre</term><term>Saudi arabia</term><term>Serum immunoglobulins</term><term>Serum protein electrophoresis</term><term>Serum triglycerides</term><term>Sibling</term><term>Skeletal survey</term><term>Syndrome</term><term>Triglyceride</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Four siblings with Papillon‐Lefèvre syndrome (3 boys and 1 girl), aged 8 to 12 at time of first diagnosis in 1978 are reported. These four patients represent the second largest sibship reported in the literature, and the only familial cases treated with etretinate for 6 years with an additional 3 1/2 year follow‐up evaluation. No long‐term side effects of etretinate were found in the children. All four patients are the product of a second cousin marriage; all demonstrate the B5 locus on HLA typing.</div></front></TEI><istex><corpusName>wiley</corpusName><keywords><teeft><json:string>etretinate</json:string><json:string>november</json:string><json:string>plantar</json:string><json:string>hyperkeratosis</json:string><json:string>triglyceride</json:string><json:string>august</json:string><json:string>hyperkeratotic</json:string><json:string>serum triglycerides</json:string><json:string>sibling</json:string><json:string>skeletal survey</json:string><json:string>syndrome</json:string><json:string>familial cases</json:string><json:string>american nchs charts</json:string><json:string>plantar feet</json:string><json:string>average dose</json:string><json:string>king faisal specialist hospital</json:string><json:string>dorsal surfaces</json:string><json:string>permanent teeth</json:string><json:string>epiphyseal lines</json:string><json:string>month intervals</json:string><json:string>pretibial areas</json:string><json:string>first diagnosis</json:string><json:string>periodontosis syndrome</json:string><json:string>fasting triglycerides</json:string><json:string>dorsal feet</json:string><json:string>research centre</json:string><json:string>last visit</json:string><json:string>saudi arabia</json:string><json:string>baseline laboratory evaluation</json:string><json:string>hair loss</json:string><json:string>keratotic plaques</json:string><json:string>serum protein electrophoresis</json:string><json:string>serum immunoglobulins</json:string><json:string>normal limits</json:string><json:string>plantar hyperkeratosis</json:string><json:string>inflammatory gingivai disease</json:string><json:string>first time</json:string><json:string>ligamentous calcification</json:string><json:string>etretinate therapy</json:string><json:string>keratosis palmoplantaris</json:string><json:string>hyperkeratosis palmoplantaris</json:string><json:string>bright erythema</json:string></teeft></keywords><author><json:item><name>Robert E. Kellum M.D.</name><affiliations><json:string>From the Department of Medicine, King Faisal Specialist Hospital and Research Centre Riyadh, Saudi Arabia</json:string><json:string>Correspondence address: Address for correspondence: Robert E. Kellum, M.D., Department of Medicine, King Faisal Specialist Hospital and Research Centre, P. O. Box 3354, Riyadh 11211, Saudi Arabia.</json:string></affiliations></json:item></author><articleId><json:string>IJD605</json:string></articleId><arkIstex>ark:/67375/WNG-MWXD9DRM-F</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>Four siblings with Papillon‐Lefèvre syndrome (3 boys and 1 girl), aged 8 to 12 at time of first diagnosis in 1978 are reported. These four patients represent the second largest sibship reported in the literature, and the only familial cases treated with etretinate for 6 years with an additional 3 1/2 year follow‐up evaluation. No long‐term side effects of etretinate were found in the children. All four patients are the product of a second cousin marriage; all demonstrate the B5 locus on HLA typing.</abstract><qualityIndicators><refBibsNative>true</refBibsNative><abstractWordCount>84</abstractWordCount><abstractCharCount>503</abstractCharCount><keywordCount>0</keywordCount><score>6.021</score><pdfWordCount>3013</pdfWordCount><pdfCharCount>18324</pdfCharCount><pdfVersion>1.6</pdfVersion><pdfPageCount>5</pdfPageCount><pdfPageSize>563 x 750 pts</pdfPageSize></qualityIndicators><title>Papillon‐Lefèvre Syndrome in Four Siblings Treated with Etretinate A Nine‐Year Evaluation</title><pmid><json:string>2531126</json:string></pmid><genre><json:string>article</json:string></genre><host><title>International Journal of Dermatology</title><language><json:string>unknown</json:string></language><doi><json:string>10.1111/(ISSN)1365-4632</json:string></doi><issn><json:string>0011-9059</json:string></issn><eissn><json:string>1365-4632</json:string></eissn><publisherId><json:string>IJD</json:string></publisherId><volume>28</volume><issue>9</issue><pages><first>605</first><last>608</last><total>4</total></pages><genre><json:string>journal</json:string></genre></host><namedEntities><unitex><date><json:string>1979</json:string><json:string>1981</json:string><json:string>1968</json:string><json:string>1970</json:string><json:string>1986</json:string><json:string>from November 1978 to July 1986</json:string><json:string>1982</json:string><json:string>1969</json:string><json:string>1983</json:string><json:string>1970s</json:string><json:string>1988</json:string><json:string>1966</json:string><json:string>1984</json:string><json:string>1989</json:string><json:string>1978</json:string></date><geogName></geogName><orgName><json:string>American NCHS</json:string><json:string>Department of Medicine, King Faisal Specialist Hospital</json:string><json:string>King Faisal Specialist Hospital and Research Centre</json:string><json:string>Research Centre Riyadh, Saudi Arabia</json:string></orgName><orgName_funder></orgName_funder><orgName_provider></orgName_provider><persName><json:string>Bernard Bendl</json:string><json:string>Daniel Mackey</json:string><json:string>Marie Roy-Boulos</json:string><json:string>Patrick Butler</json:string><json:string>P. O. Box</json:string><json:string>Despite</json:string></persName><placeName></placeName><ref_url></ref_url><ref_bibl><json:string>April 1982</json:string><json:string>Prabhu et al.</json:string><json:string>Crupper et al.</json:string><json:string>June 1982</json:string><json:string>March 1981</json:string><json:string>November 1981</json:string><json:string>March, 1988</json:string><json:string>Verma et al.</json:string><json:string>September 1988</json:string><json:string>August 1981</json:string><json:string>January 1987</json:string><json:string>November 1984</json:string><json:string>November 1978</json:string><json:string>Fayed et al.</json:string><json:string>April 1983</json:string><json:string>Hacham-Zadeh et al.</json:string><json:string>August 1979</json:string><json:string>March 1988</json:string></ref_bibl><bibl></bibl></unitex></namedEntities><ark><json:string>ark:/67375/WNG-MWXD9DRM-F</json:string></ark><categories><wos><json:string>1 - science</json:string><json:string>2 - dermatology</json:string></wos><scienceMetrix><json:string>1 - health sciences</json:string><json:string>2 - clinical medicine</json:string><json:string>3 - dermatology & venereal diseases</json:string></scienceMetrix><scopus><json:string>1 - Health Sciences</json:string><json:string>2 - Medicine</json:string><json:string>3 - Dermatology</json:string></scopus><inist><json:string>1 - sciences appliquees, technologies et medecines</json:string><json:string>2 - sciences biologiques et medicales</json:string><json:string>3 - sciences medicales</json:string></inist></categories><publicationDate>1989</publicationDate><copyrightDate>1989</copyrightDate><doi><json:string>10.1111/j.1365-4362.1989.tb02539.x</json:string></doi><id>3A990110DBFD646FA0D40990A5A357EE70CF8EC0</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/3A990110DBFD646FA0D40990A5A357EE70CF8EC0/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/3A990110DBFD646FA0D40990A5A357EE70CF8EC0/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/3A990110DBFD646FA0D40990A5A357EE70CF8EC0/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main">Papillon‐Lefèvre Syndrome in Four Siblings Treated with Etretinate A Nine‐Year Evaluation</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="1989-11"></date></publicationStmt><notesStmt><note type="content-type" subtype="article" source="article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="article"><analytic><title level="a" type="main">Papillon‐Lefèvre Syndrome in Four Siblings Treated with Etretinate A Nine‐Year Evaluation</title><author xml:id="author-0000" role="corresp"><persName><forename type="first">Robert E.</forename><surname>Kellum</surname><roleName type="degree">M.D.</roleName></persName><affiliation>From the Department of Medicine, King Faisal Specialist Hospital and Research Centre Riyadh, Saudi Arabia<address><country key="SA"></country></address></affiliation><affiliation>Address for correspondence: Robert E. Kellum, M.D., Department of Medicine, King Faisal Specialist Hospital and Research Centre, P. O. Box 3354, Riyadh 11211, Saudi Arabia.</affiliation></author><idno type="istex">3A990110DBFD646FA0D40990A5A357EE70CF8EC0</idno><idno type="ark">ark:/67375/WNG-MWXD9DRM-F</idno><idno type="DOI">10.1111/j.1365-4362.1989.tb02539.x</idno><idno type="unit">IJD605</idno><idno type="toTypesetVersion">file:IJD.IJD605.pdf</idno></analytic><monogr><title level="j" type="main">International Journal of Dermatology</title><title level="j" type="alt">INTERNATIONAL JOURNAL OF DERMATOLOGY</title><idno type="pISSN">0011-9059</idno><idno type="eISSN">1365-4632</idno><idno type="book-DOI">10.1111/(ISSN)1365-4632</idno><idno type="book-part-DOI">10.1111/ijd.1989.28.issue-9</idno><idno type="product">IJD</idno><idno type="publisherDivision">ST</idno><imprint><biblScope unit="vol">28</biblScope><biblScope unit="issue">9</biblScope><biblScope unit="page" from="605">605</biblScope><biblScope unit="page" to="608">608</biblScope><biblScope unit="page-count">4</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="1989-11"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><abstract xml:lang="en" style="main"><head>ABSTRACT:</head><p>Four siblings with Papillon‐Lefèvre syndrome (3 boys and 1 girl), aged 8 to 12 at time of first diagnosis in 1978 are reported. These four patients represent the second largest sibship reported in the literature, and the only familial cases treated with etretinate for 6 years with an additional 3 1/2 year follow‐up evaluation. No long‐term side effects of etretinate were found in the children. All four patients are the product of a second cousin marriage; all demonstrate the B5 locus on HLA typing.</p></abstract><textClass><keywords rend="tocHeading1"><term>Pharmacology and Therapeutics</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/3A990110DBFD646FA0D40990A5A357EE70CF8EC0/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Publishing Ltd</publisherName><publisherLoc>Oxford, UK</publisherLoc></publisherInfo><doi origin="wiley" registered="yes">10.1111/(ISSN)1365-4632</doi><issn type="print">0011-9059</issn><issn type="electronic">1365-4632</issn><idGroup><id type="product" value="IJD"></id><id type="publisherDivision" value="ST"></id></idGroup><titleGroup><title type="main" sort="INTERNATIONAL JOURNAL OF DERMATOLOGY">International Journal of Dermatology</title></titleGroup></publicationMeta><publicationMeta level="part" position="11009"><doi origin="wiley">10.1111/ijd.1989.28.issue-9</doi><numberingGroup><numbering type="journalVolume" number="28">28</numbering><numbering type="journalIssue" number="9">9</numbering></numberingGroup><coverDate startDate="1989-11">November 1989</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="0060500" status="forIssue"><doi origin="wiley">10.1111/j.1365-4362.1989.tb02539.x</doi><idGroup><id type="unit" value="IJD605"></id></idGroup><countGroup><count type="pageTotal" number="4"></count></countGroup><titleGroup><title type="tocHeading1">Pharmacology and Therapeutics</title></titleGroup><eventGroup><event type="firstOnline" date="2007-05-31"></event><event type="publishedOnlineFinalForm" date="2007-05-31"></event><event type="xmlConverted" agent="Converter:BPG_TO_WML3G version:2.3.2 mode:FullText source:HeaderRef result:HeaderRef" date="2010-03-04"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:4.0.1" date="2014-03-13"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-24"></event></eventGroup><numberingGroup><numbering type="pageFirst" number="605">605</numbering><numbering type="pageLast" number="608">608</numbering></numberingGroup><correspondenceTo>Address for correspondence: Robert E. Kellum, M.D., Department of Medicine, King Faisal Specialist Hospital and Research Centre, P. O. Box 3354, Riyadh 11211, Saudi Arabia.</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:IJD.IJD605.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="referenceTotal" number="16"></count><count type="linksCrossRef" number="2"></count></countGroup><titleGroup><title type="main">Papillon‐Lefèvre Syndrome in Four Siblings Treated with Etretinate A Nine‐Year Evaluation</title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#a1" corresponding="yes"><personName><givenNames>Robert E.</givenNames><familyName>Kellum</familyName><degrees>M.D.</degrees></personName></creator></creators><affiliationGroup><affiliation xml:id="a1" countryCode="SA"><unparsedAffiliation>From the Department of Medicine, King Faisal Specialist Hospital and Research Centre Riyadh, Saudi Arabia</unparsedAffiliation></affiliation></affiliationGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">ABSTRACT:</title><p>Four siblings with Papillon‐Lefèvre syndrome (3 boys and 1 girl), aged 8 to 12 at time of first diagnosis in 1978 are reported. These four patients represent the second largest sibship reported in the literature, and the only familial cases treated with etretinate for 6 years with an additional 3 1/2 year follow‐up evaluation. No long‐term side effects of etretinate were found in the children. All four patients are the product of a second cousin marriage; all demonstrate the B5 locus on HLA typing.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Papillon‐Lefèvre Syndrome in Four Siblings Treated with Etretinate A Nine‐Year Evaluation</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Papillon‐Lefèvre Syndrome in Four Siblings Treated with Etretinate A Nine‐Year Evaluation</title></titleInfo><name type="personal"><namePart type="given">Robert E.</namePart><namePart type="family">Kellum</namePart><namePart type="termsOfAddress">M.D.</namePart><affiliation>From the Department of Medicine, King Faisal Specialist Hospital and Research Centre Riyadh, Saudi Arabia</affiliation><affiliation>Correspondence address: Address for correspondence: Robert E. Kellum, M.D., Department of Medicine, King Faisal Specialist Hospital and Research Centre, P. O. Box 3354, Riyadh 11211, Saudi Arabia.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">1989-11</dateIssued><copyrightDate encoding="w3cdtf">1989</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="references">16</extent><extent unit="linksCrossRef">2</extent></physicalDescription><abstract lang="en">Four siblings with Papillon‐Lefèvre syndrome (3 boys and 1 girl), aged 8 to 12 at time of first diagnosis in 1978 are reported. These four patients represent the second largest sibship reported in the literature, and the only familial cases treated with etretinate for 6 years with an additional 3 1/2 year follow‐up evaluation. No long‐term side effects of etretinate were found in the children. All four patients are the product of a second cousin marriage; all demonstrate the B5 locus on HLA typing.</abstract><relatedItem type="host"><titleInfo><title>International Journal of Dermatology</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><identifier type="ISSN">0011-9059</identifier><identifier type="eISSN">1365-4632</identifier><identifier type="DOI">10.1111/(ISSN)1365-4632</identifier><identifier type="PublisherID">IJD</identifier><part><date>1989</date><detail type="volume"><caption>vol.</caption><number>28</number></detail><detail type="issue"><caption>no.</caption><number>9</number></detail><extent unit="pages"><start>605</start><end>608</end><total>4</total></extent></part></relatedItem><identifier type="istex">3A990110DBFD646FA0D40990A5A357EE70CF8EC0</identifier><identifier type="ark">ark:/67375/WNG-MWXD9DRM-F</identifier><identifier type="DOI">10.1111/j.1365-4362.1989.tb02539.x</identifier><identifier type="ArticleID">IJD605</identifier><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-L0C46X92-X">wiley</recordContentSource><recordOrigin>Blackwell Publishing Ltd</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/document/3A990110DBFD646FA0D40990A5A357EE70CF8EC0/metadata/json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001C68 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 001C68 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= EdenteV2
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:3A990110DBFD646FA0D40990A5A357EE70CF8EC0
|texte= Papillon‐Lefèvre Syndrome in Four Siblings Treated with Etretinate A Nine‐Year Evaluation
}}
| This area was generated with Dilib version V0.6.32. |  |