Post‐transplant lymphoproliferative disorders presenting as gingival overgrowth in patients immunosuppressed with ciclosporin. A report of two cases
Identifieur interne : 001C40 ( Istex/Corpus ); précédent : 001C39; suivant : 001C41Post‐transplant lymphoproliferative disorders presenting as gingival overgrowth in patients immunosuppressed with ciclosporin. A report of two cases
Auteurs : S. L. Rolland ; R. A. Seymour ; B. S. Wilkins ; G. Parry ; J. M. ThomasonSource :
- Journal of Clinical Periodontology [ 0303-6979 ] ; 2004-07.
English descriptors
- KwdEn :
- Cancer research, Cardiac transplantation, Ciclosporin, Ciclosporin dose, Clinical periodontology, Gingival, Gingival lymphoid, Gingival overgrowth, Gingival tissues, Heart transplantation, Immunosuppression, Large lymphoid cells, Lesion, Lymphoid, Lymphoma, Lymphoproliferative, Lymphoproliferative disorders, Oertel, Oertel riess, Oral cavity, Overgrowth, Ptld, Recent results, Riess, Risk factors, Seymour, Thomason, Transplant, Transplantation.
- Teeft :
- Cancer research, Cardiac transplantation, Ciclosporin, Ciclosporin dose, Clinical periodontology, Gingival, Gingival lymphoid, Gingival overgrowth, Gingival tissues, Heart transplantation, Immunosuppression, Large lymphoid cells, Lesion, Lymphoid, Lymphoma, Lymphoproliferative, Lymphoproliferative disorders, Oertel, Oertel riess, Oral cavity, Overgrowth, Ptld, Recent results, Riess, Risk factors, Seymour, Thomason, Transplant, Transplantation.
Abstract
Background: Post‐transplant lymphoproliferative disorder (PTLD) can occur in patients maintained on immunosuppressive therapy following transplantation. This paper describes two cases of PTLD occurring in gingival tissues, in patients receiving ciclosporin following cardiac transplantation.
Url:
DOI: 10.1111/j.1600-051X.2004.00537.x
Links to Exploration step
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<front><div type="abstract">Background: Post‐transplant lymphoproliferative disorder (PTLD) can occur in patients maintained on immunosuppressive therapy following transplantation. This paper describes two cases of PTLD occurring in gingival tissues, in patients receiving ciclosporin following cardiac transplantation.</div>
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<profileDesc><abstract xml:lang="en" style="main"><head>Abstract</head>
<p><hi rend="bold">Background: </hi>
Post‐transplant lymphoproliferative disorder (PTLD) can occur in patients maintained on immunosuppressive therapy following transplantation. This paper describes two cases of PTLD occurring in gingival tissues, in patients receiving ciclosporin following cardiac transplantation.</p>
<p><hi rend="bold">Treatment: </hi>
The lesions were localised to gingival tissues, mimicking ciclosporin‐induced gingival overgrowth. They were removed surgically and the ciclosporin dose reduced to help prevent recurrence.</p>
<p><hi rend="bold">Conclusion: </hi>
The importance of histopathological examination of all tissue removed during routine gingivectomy procedures for ciclosporin‐induced gingival overgrowth is highlighted.</p>
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<correspondenceTo>Address:
<i>Sarah L. Rolland</i>
<i>School of Dental Sciences</i>
<i>University of Newcastle</i>
<i>Framlington Place</i>
<i>Newcastle upon Tyne NE2 4BW</i>
<i>UK</i>
E‐mail: <email normalForm="s.l.rolland@ncl.ac.uk">s.l.rolland@ncl.ac.uk</email>
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<titleGroup><title type="main">Post‐transplant lymphoproliferative disorders presenting as gingival overgrowth in patients immunosuppressed with ciclosporin. A report of two cases</title>
<title type="shortAuthors">Rolland et al.</title>
<title type="short">PTLD affecting gingival tissues</title>
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<creator creatorRole="author" xml:id="cr3" affiliationRef="#a2"><personName><givenNames>B.S.</givenNames>
<familyName>Wilkins</familyName>
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<creator creatorRole="author" xml:id="cr4" affiliationRef="#a3"><personName><givenNames>G.</givenNames>
<familyName>Parry</familyName>
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<creator creatorRole="author" xml:id="cr5" affiliationRef="#a1"><personName><givenNames>J.M.</givenNames>
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<affiliationGroup><affiliation xml:id="a1"><unparsedAffiliation>School of Dental Sciences, University of Newcastle, Framlington Place, Newcastle upon Tyne, UK</unparsedAffiliation>
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<affiliation xml:id="a2"><unparsedAffiliation>Department of Pathology, Royal Victoria Infirmary, Newcastle upon Tyne, UK</unparsedAffiliation>
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<affiliation xml:id="a3" countryCode="GB"><unparsedAffiliation>Consultant Cardiac Physician, Transplant Centre, Freeman Hospital, Newcastle upon Tyne, UK</unparsedAffiliation>
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<keywordGroup xml:lang="en"><keyword xml:id="k1">ciclosporin</keyword>
<keyword xml:id="k2">gingival overgrowth</keyword>
<keyword xml:id="k3">non‐Hodgkin's lymphoma</keyword>
<keyword xml:id="k4">post‐transplant lymphoproliferative disorder</keyword>
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<abstractGroup><abstract type="main" xml:lang="en"><!--
Rolland SL, Seymour RA, Wilkins BS, Parry G, Thomason JM: Post-transplant lymphoproliferative disorders presenting as gingival overgrowth in patients immunosuppressed with ciclosporin. J Clin Periodontol 2004 doi: 10.1111/j.1600-051X.2004.00537.x. © Blackwell Munksgaard, 2004.
--><title type="main">Abstract</title>
<p><b>Background: </b>
Post‐transplant lymphoproliferative disorder (PTLD) can occur in patients maintained on immunosuppressive therapy following transplantation. This paper describes two cases of PTLD occurring in gingival tissues, in patients receiving ciclosporin following cardiac transplantation.</p>
<p><b>Treatment: </b>
The lesions were localised to gingival tissues, mimicking ciclosporin‐induced gingival overgrowth. They were removed surgically and the ciclosporin dose reduced to help prevent recurrence.</p>
<p><b>Conclusion: </b>
The importance of histopathological examination of all tissue removed during routine gingivectomy procedures for ciclosporin‐induced gingival overgrowth is highlighted.</p>
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<titleInfo type="abbreviated" lang="en"><title>PTLD affecting gingival tissues</title>
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<titleInfo type="alternative" contentType="CDATA" lang="en"><title>Post‐transplant lymphoproliferative disorders presenting as gingival overgrowth in patients immunosuppressed with ciclosporin. A report of two cases</title>
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<abstract>Background: Post‐transplant lymphoproliferative disorder (PTLD) can occur in patients maintained on immunosuppressive therapy following transplantation. This paper describes two cases of PTLD occurring in gingival tissues, in patients receiving ciclosporin following cardiac transplantation.</abstract>
<abstract>Treatment: The lesions were localised to gingival tissues, mimicking ciclosporin‐induced gingival overgrowth. They were removed surgically and the ciclosporin dose reduced to help prevent recurrence.</abstract>
<abstract>Conclusion: The importance of histopathological examination of all tissue removed during routine gingivectomy procedures for ciclosporin‐induced gingival overgrowth is highlighted.</abstract>
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