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Simultaneous versus two‐stage implant placement and guided bone regeneration in the canine: histomorphometry at 8 and 16 months

Identifieur interne : 001693 ( Istex/Corpus ); précédent : 001692; suivant : 001694

Simultaneous versus two‐stage implant placement and guided bone regeneration in the canine: histomorphometry at 8 and 16 months

Auteurs : Zvi Artzi ; Carlos E. Nemcovsky ; Haim Tal ; Evgeny Weinberg ; Miron Weinreb ; Hari Prasad ; Michael D. Rohrer ; Avital Kozlovsky

Source :

RBID : ISTEX:2ED634531437F4390A7A3CC750D936FFDCC09EAC

English descriptors

Abstract

Artz Z, Nemcovsky CE, Tal H Weinberg E, Weinreb M, Prasad H, Rohrer MD, Kozlovsky A. Simultaneous versus two‐stage implant placement and guided bone regeneration in the canine: histomorphometry at 8 and 16 months. J Clin Periodontol 2010; 37: 1029–1038. doi: 10.1111/j.1600‐051X.2010.01621.x.

Url:
DOI: 10.1111/j.1600-051X.2010.01621.x

Links to Exploration step

ISTEX:2ED634531437F4390A7A3CC750D936FFDCC09EAC

Le document en format XML

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<div type="abstract">Artz Z, Nemcovsky CE, Tal H Weinberg E, Weinreb M, Prasad H, Rohrer MD, Kozlovsky A. Simultaneous versus two‐stage implant placement and guided bone regeneration in the canine: histomorphometry at 8 and 16 months. J Clin Periodontol 2010; 37: 1029–1038. doi: 10.1111/j.1600‐051X.2010.01621.x.</div>
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<p>Artz Z, Nemcovsky CE, Tal H Weinberg E, Weinreb M, Prasad H, Rohrer MD, Kozlovsky A. Simultaneous
<hi rend="italic">versus</hi>
two‐stage implant placement and guided bone regeneration in the canine: histomorphometry at 8 and 16 months. J Clin Periodontol 2010; 37: 1029–1038. doi: 10.1111/j.1600‐051X.2010.01621.x.</p>
Abstract
<p>
<hi rend="bold">Aim: </hi>
To compare the effect of timing of implant placement and guided bone regeneration (GBR) procedure on osseointegration and newly formed bone at 8 and 16 months.</p>
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<hi rend="bold">Material and Methods: </hi>
In seven dogs, four different sites were bilaterally established: (1) an implant placed in a 6‐month healed (6m‐GBR) bovine bone mineral (BBM) grafted site; (2) a simultaneously placed implant with the grafted BBM (Si‐GBR) followed by a membrane coverage; (3) an implant placed in a membrane‐protected non‐grafted defect; and (4) an implant placement in a naturally healed site (Cont). Histomorphometry was obtained at 8 and 16 months post‐implant placement. Bone–implant contact (BIC), crestal bone resorption (CBR), vertical intra‐bony (VIB) defect, bone (BAF) and particle (PAF) area fractions, and osteoconductivity (CON) levels were measured.</p>
<p>
<hi rend="bold">Results: </hi>
In all sites, BIC ranged between 62% and 79% with no significant differences. PAF ranged from 17% to 27%, with no effect of time. At 8 and 16 months, BAF was significantly smaller at the Si‐GBR site when compared with all other sites, CON was significantly greater at the 6m‐GBR site, and CBR and VIB were significantly smaller at the 6m‐GBR when compared with the Si‐GBR sites.</p>
<p>
<hi rend="bold">Conclusions: </hi>
The simultaneous and delayed techniques both showed a similar osseointegration level over time. However, the staged approach showed enhanced newly formed bone, higher osteoconduction around the grafted mineral, less CBR, and smaller vertical bone defect over time compared with the combined approach.</p>
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<i>Zvi Artzi</i>
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E‐mail:
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<p>Artz Z, Nemcovsky CE, Tal H Weinberg E, Weinreb M, Prasad H, Rohrer MD, Kozlovsky A. Simultaneous
<i>versus</i>
two‐stage implant placement and guided bone regeneration in the canine: histomorphometry at 8 and 16 months. J Clin Periodontol 2010; 37: 1029–1038. doi: 10.1111/j.1600‐051X.2010.01621.x.</p>
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<title type="main">Abstract</title>
<p>
<b>Aim: </b>
To compare the effect of timing of implant placement and guided bone regeneration (GBR) procedure on osseointegration and newly formed bone at 8 and 16 months.</p>
<p>
<b>Material and Methods: </b>
In seven dogs, four different sites were bilaterally established: (1) an implant placed in a 6‐month healed (6m‐GBR) bovine bone mineral (BBM) grafted site; (2) a simultaneously placed implant with the grafted BBM (Si‐GBR) followed by a membrane coverage; (3) an implant placed in a membrane‐protected non‐grafted defect; and (4) an implant placement in a naturally healed site (Cont). Histomorphometry was obtained at 8 and 16 months post‐implant placement. Bone–implant contact (BIC), crestal bone resorption (CBR), vertical intra‐bony (VIB) defect, bone (BAF) and particle (PAF) area fractions, and osteoconductivity (CON) levels were measured.</p>
<p>
<b>Results: </b>
In all sites, BIC ranged between 62% and 79% with no significant differences. PAF ranged from 17% to 27%, with no effect of time. At 8 and 16 months, BAF was significantly smaller at the Si‐GBR site when compared with all other sites, CON was significantly greater at the 6m‐GBR site, and CBR and VIB were significantly smaller at the 6m‐GBR when compared with the Si‐GBR sites.</p>
<p>
<b>Conclusions: </b>
The simultaneous and delayed techniques both showed a similar osseointegration level over time. However, the staged approach showed enhanced newly formed bone, higher osteoconduction around the grafted mineral, less CBR, and smaller vertical bone defect over time compared with the combined approach.</p>
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<b>Conflict of interest and sources of funding statement</b>

The authors declare no conflict of interest at any part of the study.
This study was funded by the Osteology Foundation and by the Gerald A. Niznick Chair of Implant Dentistry and the Alpha Omega Research Fund, Tel Aviv University. The authors are indebted to Biomet 3i for providing the implants; to Geistlich Biomaterials for providing the biomaterials to Dr. Naam Kariv, Mr. Haim Barki, and Mr. Neria Davidov for the animal care; to Mrs. Ilana Gelernter for the statistical analysis; and to Rita Lazar (EASE) for editorial assistance.</p>
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<abstract>Artz Z, Nemcovsky CE, Tal H Weinberg E, Weinreb M, Prasad H, Rohrer MD, Kozlovsky A. Simultaneous versus two‐stage implant placement and guided bone regeneration in the canine: histomorphometry at 8 and 16 months. J Clin Periodontol 2010; 37: 1029–1038. doi: 10.1111/j.1600‐051X.2010.01621.x.</abstract>
<abstract>Aim: To compare the effect of timing of implant placement and guided bone regeneration (GBR) procedure on osseointegration and newly formed bone at 8 and 16 months. Material and Methods: In seven dogs, four different sites were bilaterally established: (1) an implant placed in a 6‐month healed (6m‐GBR) bovine bone mineral (BBM) grafted site; (2) a simultaneously placed implant with the grafted BBM (Si‐GBR) followed by a membrane coverage; (3) an implant placed in a membrane‐protected non‐grafted defect; and (4) an implant placement in a naturally healed site (Cont). Histomorphometry was obtained at 8 and 16 months post‐implant placement. Bone–implant contact (BIC), crestal bone resorption (CBR), vertical intra‐bony (VIB) defect, bone (BAF) and particle (PAF) area fractions, and osteoconductivity (CON) levels were measured. Results: In all sites, BIC ranged between 62% and 79% with no significant differences. PAF ranged from 17% to 27%, with no effect of time. At 8 and 16 months, BAF was significantly smaller at the Si‐GBR site when compared with all other sites, CON was significantly greater at the 6m‐GBR site, and CBR and VIB were significantly smaller at the 6m‐GBR when compared with the Si‐GBR sites. Conclusions: The simultaneous and delayed techniques both showed a similar osseointegration level over time. However, the staged approach showed enhanced newly formed bone, higher osteoconduction around the grafted mineral, less CBR, and smaller vertical bone defect over time compared with the combined approach.</abstract>
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