Serveur d'exploration sur le patient édenté

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Is implanto-prosthodontic treatment available for haemodialysis patients?

Identifieur interne : 000977 ( Istex/Corpus ); précédent : 000976; suivant : 000978

Is implanto-prosthodontic treatment available for haemodialysis patients?

Auteurs : Maciej Dijakiewicz ; Andrzej Wojtowicz ; Joanna Dijakiewicz ; Violetta Szycik ; Przemysław Rutkowski ; Bolesław Rutkowski

Source :

RBID : ISTEX:13B3718909E63811E1D3CEFB48D89F1BE186EF43
Url:
DOI: 10.1093/ndt/gfm317

Links to Exploration step

ISTEX:13B3718909E63811E1D3CEFB48D89F1BE186EF43

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<name>
<surname>Szycik</surname>
<given-names>Violetta</given-names>
</name>
<xref ref-type="aff" rid="AFF1">
<sup>1</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Rutkowski</surname>
<given-names>Przemysław</given-names>
</name>
<xref ref-type="aff" rid="AFF1">
<sup>4</sup>
</xref>
</contrib>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Rutkowski</surname>
<given-names>Bolesław</given-names>
</name>
<xref ref-type="aff" rid="AFF1">
<sup>4</sup>
</xref>
</contrib>
</contrib-group>
<aff id="AFF1">
<sup>1</sup>
Department of Oral Surgery
<break></break>
Gdansk Medical University
<break></break>
<sup>2</sup>
Department of Oral Surgery
<break></break>
Warsaw Department of
<break></break>
Oral Surgery
<break></break>
<sup>3</sup>
Department of Pediatric
<break></break>
Dentistry, Gdansk
<break></break>
Medical University,
<break></break>
<sup>4</sup>
Department of Nephrology, Transplantology
<break></break>
and Internal Medicine Gdansk Medical University
<break></break>
Poland</aff>
<author-notes>
<corresp>Email:
<email>bolo@amg.gda.pl</email>
</corresp>
<fn>
<p>See
<ext-link ext-link-type="uri" xlink:href="http://www.oxfordjournals.org/our_journals/ndtplus/">http://www.oxfordjournals.org/our_journals/ndtplus/</ext-link>
</p>
</fn>
</author-notes>
<pub-date pub-type="ppub">
<month>9</month>
<year>2007</year>
</pub-date>
<pub-date pub-type="epub">
<day>25</day>
<month>5</month>
<year>2007</year>
</pub-date>
<volume>22</volume>
<issue>9</issue>
<fpage>2722</fpage>
<lpage>2724</lpage>
<copyright-statement>© The Author [2007]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org</copyright-statement>
<copyright-year>2007</copyright-year>
</article-meta>
</front>
<body>
<p>Sir,</p>
<p>Dental problems and complications in renal patients are infrequently discussed in nephrological journals. In this context, the appearance of two publications (Original Article and Editorial Comment) dedicated to this underestimated, but very important problem in NDT seems a very positive exception [
<xref ref-type="bibr" rid="B1">1</xref>
,
<xref ref-type="bibr" rid="B2">2</xref>
]. Underdiagnosed and untreated periodontitis and other gingival changes may in consequence lead to odontogenic bacteriemic episodes and the development of potentially serious infections, e.g. infective endocarditis. One must remember that ESRD patients are immunodeficient, a condition caused by disturbances of the cellular and humoral immunological response [
<xref ref-type="bibr" rid="B3">3</xref>
]. On the other hand, patients after renal transplantation may develop a very specific type of gingival hyperplasia and subsequent periodontitis caused by cyclosporine. We recently published our experience with this subject, taking into account treatment performed on patients after successful renal transplantation [
<xref ref-type="bibr" rid="B4">4</xref>
,
<xref ref-type="bibr" rid="B5">5</xref>
]. In the second paper, we proposed a diagnostic and therapeutic algorithm based on our experience and literature search. We wish to draw attention to another important issue related to the availability of modern dental implantology in ESRD patients. In their comments, Craig
<italic>et al</italic>
. [
<xref ref-type="bibr" rid="B1">1</xref>
] suggested that ‘osseous periodontal surgical procedures such as bone grafting or dental implants may be contraindicated in patients with significant renal osteodystrophy’. This suggestion was based on the results of studies performed several years ago. Unfortunately, this type of opinion is quite common both in dental and nephrological literature [
<xref ref-type="bibr" rid="B6">6</xref>
]. In the last 5 years, we have performed several studies in patients treated with maintenance haemodialysis and afte successful renal transplantation leading to opposite conclusions, showing that this type of treatment is applicable to ESRD patients [
<xref ref-type="bibr" rid="B7 B8 B9">7–9</xref>
]. In
<xref ref-type="table" rid="T1">Table 1</xref>
, the availability of implants in 100 haemodialysis patients is shown. Results were compared with a control group of 50 healthy persons, with similar age and gender. Studies included radiometric analysis in digital dental panoramic tomography (DPT) using implantological template by Nobel Biocare. Multivariance analysis consists of:
<list list-type="bullet">
<list-item>
<p>radiometric, mathematical Fourier's and densitometric analysis of the jaw bones;</p>
</list-item>
<list-item>
<p>Nobel Direct implants simulation, using implantological template and digital pantomography system Planmeca, Vix Win 2000;</p>
</list-item>
<list-item>
<p>histological and histomorphometrical analysis of jaws bone tissue samples</p>
</list-item>
<list-item>
<p>jaws mineral bone qualitative analysis using EPR (electron paramagnetic resonance methodology)</p>
</list-item>
<list-item>
<p>evaluation of biochemical markers of bone metabolism (calcium, phosphate, PTH, alkaline phosphatase). Analysis of the obtained results performed using multiple regression and correlation tests (Statistica 7,0, StatSoft, Tulsa, USA) Evaluation of the degree of jaw bones decline in place of dental implants installation in reference to the status of renal osteodystrophy: frequency and duration of the haemodialysis period was also performed.</p>
</list-item>
</list>
<table-wrap id="T1">
<label>
<bold>Table 1.</bold>
</label>
<caption>
<p>Comparison of the availability of implant installation at maxilla or mandible between control group and HD patients</p>
</caption>
<table frame="hsides">
<thead align="left">
<tr>
<th colspan="3">Availability of implant installation Place/Group ◂ (%)</th>
<th>No possibility</th>
<th>10 mm length implant (%)</th>
<th>13 mm length implant (%)</th>
<th>16 mm length implant (%)</th>
</tr>
</thead>
<tbody align="left">
<tr>
<td>Maxilla</td>
<td>Control group
<italic>n</italic>
= 50</td>
<td></td>
<td></td>
<td>28</td>
<td>24</td>
<td>48</td>
</tr>
<tr>
<td></td>
<td>HD Patients
<italic>n</italic>
= 100</td>
<td>Dialysed ≤2 years</td>
<td></td>
<td>40</td>
<td>40</td>
<td>20</td>
</tr>
<tr>
<td></td>
<td></td>
<td>Dialysed ≤4 years</td>
<td></td>
<td>30</td>
<td>53</td>
<td>17</td>
</tr>
<tr>
<td></td>
<td></td>
<td>Dialysed ≤6 years</td>
<td></td>
<td>28</td>
<td>55</td>
<td>28</td>
</tr>
<tr>
<td>Mandible</td>
<td>Control group
<italic>n</italic>
= 50</td>
<td></td>
<td></td>
<td>20</td>
<td>52</td>
<td>28</td>
</tr>
<tr>
<td></td>
<td>HD Patients
<italic>n</italic>
= 100</td>
<td>Dialysed ≤2 years</td>
<td>4</td>
<td>44</td>
<td>44</td>
<td>8</td>
</tr>
<tr>
<td></td>
<td></td>
<td>Dialysed ≤4 years</td>
<td>11</td>
<td>51</td>
<td>33</td>
<td>5</td>
</tr>
<tr>
<td></td>
<td></td>
<td>Dialysed ≤6 years</td>
<td>13</td>
<td>37</td>
<td>42</td>
<td>8</td>
</tr>
</tbody>
</table>
</table-wrap>
</p>
<p>Detailed data showing the results of consecutive steps of examination performed in ESRD patients were published elsewhere [
<xref ref-type="bibr" rid="B7 B8 B9">7–9</xref>
].</p>
<p>The analysis shows a decreased quantity and quality of bone tissue of the maxilla and mandible in renal osteodystrophy. Nevertheless, according to internationally recognized standards, these changes were not a contraindication to implantological treatment. This thesis was confirmed in clinical practice because we observed normal function of the implants in patients suffering from renal osteodystrophy, who had received implants many years previously. In general, these patients need more frequent professional advice on oral hygiene and microbiological control using RT-PCR (unpublished data).</p>
<p>Only four patients were potentially excluded from this procedure dependent on the time of haemodialysis therapy, due to the inappropriate state of their mandible (low bone density and considerable bone decrease). No exclusions were noted on potential implant installation in the maxilla.</p>
<p>In conclusion, the results of our studies clearly show that in the large majority of patients on renal replacement therapy, implantological treatment is possible. Nevertheless, taking into account all specific circumstances (potential use of immunosuppression, higher risk of infection, etc.) it is necessary to establish a special diagnostic and therapeutical algorithm regulating implantological procedures in these patients [
<xref ref-type="bibr" rid="B10">10</xref>
].</p>
<p>
<italic>Conflict of interest statement</italic>
. None declared.</p>
</body>
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<title>Is implanto-prosthodontic treatment available for haemodialysis patients?</title>
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<title>Is implanto-prosthodontic treatment available for haemodialysis patients?</title>
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<name type="personal">
<namePart type="given">Maciej</namePart>
<namePart type="family">Dijakiewicz</namePart>
<affiliation>Department of Oral SurgeryGdansk Medical UniversityDepartment of Oral SurgeryWarsaw Department ofOral SurgeryDepartment of PediatricDentistry, GdanskMedical University,Department of Nephrology, Transplantologyand Internal Medicine Gdansk Medical UniversityPoland</affiliation>
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<name type="personal">
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<affiliation>Department of Oral SurgeryGdansk Medical UniversityDepartment of Oral SurgeryWarsaw Department ofOral SurgeryDepartment of PediatricDentistry, GdanskMedical University,Department of Nephrology, Transplantologyand Internal Medicine Gdansk Medical UniversityPoland</affiliation>
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</role>
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<name type="personal">
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<affiliation>Department of Oral SurgeryGdansk Medical UniversityDepartment of Oral SurgeryWarsaw Department ofOral SurgeryDepartment of PediatricDentistry, GdanskMedical University,Department of Nephrology, Transplantologyand Internal Medicine Gdansk Medical UniversityPoland</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
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<name type="personal">
<namePart type="given">Violetta</namePart>
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<affiliation>Department of Oral SurgeryGdansk Medical UniversityDepartment of Oral SurgeryWarsaw Department ofOral SurgeryDepartment of PediatricDentistry, GdanskMedical University,Department of Nephrology, Transplantologyand Internal Medicine Gdansk Medical UniversityPoland</affiliation>
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<affiliation>Department of Oral SurgeryGdansk Medical UniversityDepartment of Oral SurgeryWarsaw Department ofOral SurgeryDepartment of PediatricDentistry, GdanskMedical University,Department of Nephrology, Transplantologyand Internal Medicine Gdansk Medical UniversityPoland</affiliation>
<affiliation>E-mail: bolo@amg.gda.pl</affiliation>
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<start>2722</start>
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   |texte=   Is implanto-prosthodontic treatment available for haemodialysis patients?
}}

Wicri

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