Prevalence of oral mucosal lesions in adults undergoing highly active antiretroviral therapy in Hong Kong
Identifieur interne : 000955 ( Istex/Corpus ); précédent : 000954; suivant : 000956Prevalence of oral mucosal lesions in adults undergoing highly active antiretroviral therapy in Hong Kong
Auteurs : Mahendra Perera ; Peter Chiu Shun Tsang ; Lakshman Samaranayake ; Man Po Lee ; Patrick LiSource :
- Journal of Investigative and Clinical Dentistry [ 2041-1618 ] ; 2012-08.
English descriptors
- KwdEn :
- Active antiretroviral therapy, Antiretroviral, Baseline, Blackwell publishing asia, Buffering capacity, Candidiasis, Cohort, Control group, Disease control, Ethnic chinese, Gingival, Haart, Hong kong, Human virus, Lesion, Leukoplakia, Linear gingival erythema, Mucosal, Mucosal lesions, Newer haart, Oral candidiasis, Oral lesions, Oral manifestations, Oral mucosal lesions, Oral pathol, Oral surg, Parotid, Parotid enlargement, Pathol, Patient group, Prevalence, Queen elizabeth hospital, Radiol endod, Salivary, Sarcoma, Study group, Transcriptase inhibitors, Ulceration, Unstimulated, Viral load.
- Teeft :
- Active antiretroviral therapy, Antiretroviral, Baseline, Blackwell publishing asia, Buffering capacity, Candidiasis, Cohort, Control group, Disease control, Ethnic chinese, Gingival, Haart, Hong kong, Human virus, Lesion, Leukoplakia, Linear gingival erythema, Mucosal, Mucosal lesions, Newer haart, Oral candidiasis, Oral lesions, Oral manifestations, Oral mucosal lesions, Oral pathol, Oral surg, Parotid, Parotid enlargement, Pathol, Patient group, Prevalence, Queen elizabeth hospital, Radiol endod, Salivary, Sarcoma, Study group, Transcriptase inhibitors, Ulceration, Unstimulated, Viral load.
Abstract
Aim: Highly active antiretroviral therapy (HAART) has altered the prevalence and incidence of oral mucosal lesions of HIV infection. Recent reports show a variation in the prevalence of oral mucosal lesions in different population groups. Understanding the prevalence of these lesions is of paramount importance in the efficient delivery of dental care to such cohorts. The aim of the present study was to investigate the prevalence of oral mucosal lesions and salivary parameters during HAART in an ethnic Chinese cohort in Hong Kong.
Url:
DOI: 10.1111/j.2041-1626.2012.00124.x
Links to Exploration step
ISTEX:13256BD6AB95B1D4522B6088E9A9350480871299Le document en format XML
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erythema</term><term>Mucosal</term><term>Mucosal lesions</term><term>Newer haart</term><term>Oral candidiasis</term><term>Oral lesions</term><term>Oral manifestations</term><term>Oral mucosal lesions</term><term>Oral pathol</term><term>Oral surg</term><term>Parotid</term><term>Parotid enlargement</term><term>Pathol</term><term>Patient group</term><term>Prevalence</term><term>Queen elizabeth hospital</term><term>Radiol endod</term><term>Salivary</term><term>Sarcoma</term><term>Study group</term><term>Transcriptase inhibitors</term><term>Ulceration</term><term>Unstimulated</term><term>Viral load</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Active antiretroviral therapy</term><term>Antiretroviral</term><term>Baseline</term><term>Blackwell publishing asia</term><term>Buffering capacity</term><term>Candidiasis</term><term>Cohort</term><term>Control group</term><term>Disease control</term><term>Ethnic chinese</term><term>Gingival</term><term>Haart</term><term>Hong kong</term><term>Human virus</term><term>Lesion</term><term>Leukoplakia</term><term>Linear gingival erythema</term><term>Mucosal</term><term>Mucosal lesions</term><term>Newer haart</term><term>Oral candidiasis</term><term>Oral lesions</term><term>Oral manifestations</term><term>Oral mucosal lesions</term><term>Oral pathol</term><term>Oral surg</term><term>Parotid</term><term>Parotid enlargement</term><term>Pathol</term><term>Patient group</term><term>Prevalence</term><term>Queen elizabeth hospital</term><term>Radiol endod</term><term>Salivary</term><term>Sarcoma</term><term>Study group</term><term>Transcriptase inhibitors</term><term>Ulceration</term><term>Unstimulated</term><term>Viral load</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract">Aim: Highly active antiretroviral therapy (HAART) has altered the prevalence and incidence of oral mucosal lesions of HIV infection. Recent reports show a variation in the prevalence of oral mucosal lesions in different population groups. Understanding the prevalence of these lesions is of paramount importance in the efficient delivery of dental care to such cohorts. 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Recent reports show a variation in the prevalence of oral mucosal lesions in different population groups. Understanding the prevalence of these lesions is of paramount importance in the efficient delivery of dental care to such cohorts. The aim of the present study was to investigate the prevalence of oral mucosal lesions and salivary parameters during HAART in an ethnic Chinese cohort in Hong Kong.</abstract><qualityIndicators><score>7.108</score><pdfWordCount>4112</pdfWordCount><pdfCharCount>26652</pdfCharCount><pdfVersion>1.3</pdfVersion><pdfPageCount>7</pdfPageCount><pdfPageSize>595.276 x 779.528 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractWordCount>83</abstractWordCount><abstractCharCount>536</abstractCharCount><keywordCount>5</keywordCount></qualityIndicators><title>Prevalence of oral mucosal lesions in adults undergoing highly active antiretroviral therapy in Hong Kong</title><pmid><json:string>22573355</json:string></pmid><genre><json:string>article</json:string></genre><host><title>Journal of Investigative and Clinical Dentistry</title><language><json:string>unknown</json:string></language><doi><json:string>10.1111/(ISSN)2041-1626</json:string></doi><issn><json:string>2041-1618</json:string></issn><eissn><json:string>2041-1626</json:string></eissn><publisherId><json:string>JICD</json:string></publisherId><volume>3</volume><issue>3</issue><pages><first>208</first><last>214</last><total>7</total></pages><genre><json:string>journal</json:string></genre><subject><json:item><value>ORIGINAL ARTICLE</value></json:item></subject></host><namedEntities><unitex><date><json:string>2012</json:string><json:string>from June 2007 to June 2009</json:string></date><geogName></geogName><orgName><json:string>Blackwell Publishing Asia Pty Ltd</json:string><json:string>Queen Elizabeth Hospital, Hong Kong</json:string><json:string>University of Hong Kong</json:string><json:string>Cluster</json:string><json:string>Hospital Road, Hong Kong, China</json:string><json:string>US and UK</json:string><json:string>Classification and diagnostic criteria for oral lesions in HIV infection</json:string><json:string>Bayer Diagnostics</json:string><json:string>Blackwell Publishing Asia Pty</json:string><json:string>Queen Elizabeth Hospital, Hong Kong, China Keywords</json:string><json:string>Hospital, The University of Hong Kong</json:string></orgName><orgName_funder></orgName_funder><orgName_provider></orgName_provider><persName><json:string>Elizabeth Hospital</json:string><json:string>Hong Kong</json:string><json:string>Shun Tsang</json:string><json:string>Peter Chiu</json:string><json:string>Clinic</json:string><json:string>Lakshman Samaranayake</json:string><json:string>Phillip Dental</json:string><json:string>Recent</json:string><json:string>Patrick Li</json:string></persName><placeName><json:string>IL</json:string><json:string>Emeryville</json:string><json:string>Hong Kong</json:string><json:string>Lichtenstein</json:string><json:string>Helsinki</json:string><json:string>China</json:string><json:string>Europe</json:string><json:string>USA</json:string><json:string>Chicago</json:string><json:string>CA</json:string><json:string>Tanzania</json:string><json:string>Schaan</json:string></placeName><ref_url></ref_url><ref_bibl><json:string>Ceballos-Salobrena et al.</json:string><json:string>Schmidt-Westhausen et al.</json:string><json:string>Amador et al.</json:string><json:string>Navazesh et al.</json:string><json:string>M. Perera et al.</json:string></ref_bibl><bibl></bibl></unitex></namedEntities><ark><json:string>ark:/67375/WNG-78S8KKC7-T</json:string></ark><categories><wos></wos><scienceMetrix></scienceMetrix><scopus><json:string>1 - Health Sciences</json:string><json:string>2 - Medicine</json:string><json:string>3 - General Medicine</json:string></scopus></categories><publicationDate>2012</publicationDate><copyrightDate>2012</copyrightDate><doi><json:string>10.1111/j.2041-1626.2012.00124.x</json:string></doi><id>13256BD6AB95B1D4522B6088E9A9350480871299</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/13256BD6AB95B1D4522B6088E9A9350480871299/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/13256BD6AB95B1D4522B6088E9A9350480871299/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/13256BD6AB95B1D4522B6088E9A9350480871299/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main">Prevalence of oral mucosal lesions in adults undergoing highly active antiretroviral therapy in Hong Kong</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><availability><licence>© 2012 Blackwell Publishing Asia Pty Ltd</licence></availability><date type="published" when="2012-08"></date></publicationStmt><notesStmt><note type="content-type" subtype="article" source="article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="article"><analytic><title level="a" type="main">Prevalence of oral mucosal lesions in adults undergoing highly active antiretroviral therapy in Hong Kong</title><title level="a" type="short">Highly active antiretroviral therapy</title><author xml:id="author-0000"><persName><forename type="first">Mahendra</forename><surname>Perera</surname></persName><affiliation> Faculty of Dentistry, University of Hong Kong, Hong Kong, China</affiliation></author><author xml:id="author-0001"><persName><forename type="first">Peter Chiu Shun</forename><surname>Tsang</surname></persName><affiliation> Faculty of Dentistry, University of Hong Kong, Hong Kong, China</affiliation></author><author xml:id="author-0002"><persName><forename type="first">Lakshman</forename><surname>Samaranayake</surname></persName><affiliation> Faculty of Dentistry, University of Hong Kong, Hong Kong, China</affiliation></author><author xml:id="author-0003"><persName><forename type="first">Man Po</forename><surname>Lee</surname></persName><affiliation> AIDS Clinical Service, Queen Elizabeth Hospital, Hong Kong, China</affiliation></author><author xml:id="author-0004"><persName><forename type="first">Patrick</forename><surname>Li</surname></persName><affiliation> AIDS Clinical Service, Queen Elizabeth Hospital, Hong Kong, China</affiliation></author><idno type="istex">13256BD6AB95B1D4522B6088E9A9350480871299</idno><idno type="ark">ark:/67375/WNG-78S8KKC7-T</idno><idno type="DOI">10.1111/j.2041-1626.2012.00124.x</idno><idno type="unit">JICD124</idno><idno type="toTypesetVersion">file:JICD.JICD124.pdf</idno></analytic><monogr><title level="j" type="main">Journal of Investigative and Clinical Dentistry</title><title level="j" type="alt">JOURNAL OF INVESTIGATIVE AND CLINICAL DENTISTRY</title><idno type="pISSN">2041-1618</idno><idno type="eISSN">2041-1626</idno><idno type="book-DOI">10.1111/(ISSN)2041-1626</idno><idno type="book-part-DOI">10.1111/jicd.2012.3.issue-3</idno><idno type="product">JICD</idno><idno type="publisherDivision">ST</idno><imprint><biblScope unit="vol">3</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="208">208</biblScope><biblScope unit="page" to="214">214</biblScope><biblScope unit="page-count">7</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2012-08"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><abstract xml:lang="en" style="main"><head>Abstract</head><p><hi rend="bold">Aim: </hi> Highly active antiretroviral therapy (HAART) has altered the prevalence and incidence of oral mucosal lesions of HIV infection. Recent reports show a variation in the prevalence of oral mucosal lesions in different population groups. Understanding the prevalence of these lesions is of paramount importance in the efficient delivery of dental care to such cohorts. The aim of the present study was to investigate the prevalence of oral mucosal lesions and salivary parameters during HAART in an ethnic Chinese cohort in Hong Kong.</p><p><hi rend="bold">Methods: </hi> A cross‐sectional estimation of the prevalence of oral mucosal lesions was carried out in 101 HIV‐infected ethnic Chinese in Hong Kong using the European Community–Clearinghouse classification.</p><p><hi rend="bold">Results: </hi> The prevalence of oral mucosal lesions was more common in patients who were classified at baseline as Centers for Disease Control (CDC) C3 category than CDC A2, A3, B2, and B3 (<hi rend="italic">P</hi> < 0.05). An overall prevalence of 1.98% was observed for oral Kaposi’s sarcoma. Additionally, the HIV group on HAART (0.37 ± 0.23 mL/min) had significantly lower salivary flow rates (<hi rend="italic">P</hi> < 0.01) compared with the healthy group (0.49 ± 0.15 mL/min).</p><p><hi rend="bold">Conclusions: </hi> Although HAART appears to markedly reduce the prevalence of oral mucosal lesions during the course of HIV disease, regular systematic oral screening is still warranted for such populations for the early diagnosis and management of pathologies, such as Kaposi’s sarcoma.</p></abstract><textClass><keywords xml:lang="en"><term xml:id="k1">highly active antiretroviral therapy</term><term xml:id="k2">Hong Kong</term><term xml:id="k3">human immunodeficiency virus</term><term xml:id="k4">infection</term><term xml:id="k5">oral mucosal lesion</term></keywords><keywords rend="tocHeading1"><term>ORIGINAL ARTICLES</term></keywords><keywords rend="tocHeading2"><term>Oral Medicine</term></keywords><keywords rend="articleCategory"><term>ORIGINAL ARTICLE</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/13256BD6AB95B1D4522B6088E9A9350480871299/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Publishing Ltd</publisherName><publisherLoc>Oxford, UK</publisherLoc></publisherInfo><doi origin="wiley" registered="yes">10.1111/(ISSN)2041-1626</doi><issn type="print">2041-1618</issn><issn type="electronic">2041-1626</issn><idGroup><id type="product" value="JICD"></id><id type="publisherDivision" value="ST"></id></idGroup><titleGroup><title type="main" sort="JOURNAL OF INVESTIGATIVE AND CLINICAL DENTISTRY">Journal of Investigative and Clinical Dentistry</title></titleGroup></publicationMeta><publicationMeta level="part" position="08103"><doi origin="wiley">10.1111/jicd.2012.3.issue-3</doi><numberingGroup><numbering type="journalVolume" number="3">3</numbering><numbering type="journalIssue" number="3">3</numbering></numberingGroup><coverDate startDate="2012-08">August 2012</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="9" status="forIssue"><doi origin="wiley">10.1111/j.2041-1626.2012.00124.x</doi><idGroup><id type="unit" value="JICD124"></id></idGroup><countGroup><count type="pageTotal" number="7"></count></countGroup><titleGroup><title type="tocHeading1">ORIGINAL ARTICLES</title><title type="tocHeading2">Oral Medicine</title><title type="articleCategory">ORIGINAL ARTICLE<link href="#artCateg-note"></link></title></titleGroup><copyright>© 2012 Blackwell Publishing Asia Pty Ltd</copyright><eventGroup><event type="xmlConverted" agent="Converter:BPG_TO_WML3G version:3.1.6 mode:FullText" date="2012-07-26"></event><event agent="SPS" date="2012-07-26" type="xmlCorrected"></event><event type="publishedOnlineEarlyUnpaginated" date="2012-05-10"></event><event type="firstOnline" date="2012-05-10"></event><event type="publishedOnlineFinalForm" date="2012-08-06"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:4.0.1" date="2014-03-20"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.3.4 mode:FullText" date="2015-02-25"></event></eventGroup><numberingGroup><numbering type="pageFirst" number="208">208</numbering><numbering type="pageLast" number="214">214</numbering></numberingGroup><correspondenceTo>Dr Peter Chiu Shun Tsang, Prince Phillip Dental Hospital, The University of Hong Kong, 34 Hospital Road, Hong Kong, China.
Tel: +852‐2859‐0310
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Email: <email>csptsang@hkucc.hku.hk</email></correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:JICD.JICD124.pdf"></link></linkGroup></publicationMeta><contentMeta><unparsedEditorialHistory>Received 21 December 2011; accepted 7 January 2012.</unparsedEditorialHistory><countGroup><count type="figureTotal" number="1"></count><count type="tableTotal" number="4"></count></countGroup><titleGroup><title type="main">Prevalence of oral mucosal lesions in adults undergoing highly active antiretroviral therapy in Hong Kong</title><title type="shortAuthors">M. Perera <i>et al.</i></title><title type="short">Highly active antiretroviral therapy</title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#a1"><personName><givenNames>Mahendra</givenNames><familyName>Perera</familyName></personName></creator><creator creatorRole="author" xml:id="cr2" affiliationRef="#a1"><personName><givenNames>Peter Chiu Shun</givenNames><familyName>Tsang</familyName></personName></creator><creator creatorRole="author" xml:id="cr3" affiliationRef="#a1"><personName><givenNames>Lakshman</givenNames><familyName>Samaranayake</familyName></personName></creator><creator creatorRole="author" xml:id="cr4" affiliationRef="#a2"><personName><givenNames>Man Po</givenNames><familyName>Lee</familyName></personName></creator><creator creatorRole="author" xml:id="cr5" affiliationRef="#a2"><personName><givenNames>Patrick</givenNames><familyName>Li</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="a1"><unparsedAffiliation> Faculty of Dentistry, University of Hong Kong, Hong Kong, China</unparsedAffiliation></affiliation><affiliation xml:id="a2"><unparsedAffiliation> AIDS Clinical Service, Queen Elizabeth Hospital, Hong Kong, China</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en"><keyword xml:id="k1">highly active antiretroviral therapy</keyword><keyword xml:id="k2">Hong Kong</keyword><keyword xml:id="k3">human immunodeficiency virus</keyword><keyword xml:id="k4">infection</keyword><keyword xml:id="k5">oral mucosal lesion</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p><b>Aim: </b> Highly active antiretroviral therapy (HAART) has altered the prevalence and incidence of oral mucosal lesions of HIV infection. Recent reports show a variation in the prevalence of oral mucosal lesions in different population groups. Understanding the prevalence of these lesions is of paramount importance in the efficient delivery of dental care to such cohorts. The aim of the present study was to investigate the prevalence of oral mucosal lesions and salivary parameters during HAART in an ethnic Chinese cohort in Hong Kong.</p><p><b>Methods: </b> A cross‐sectional estimation of the prevalence of oral mucosal lesions was carried out in 101 HIV‐infected ethnic Chinese in Hong Kong using the European Community–Clearinghouse classification.</p><p><b>Results: </b> The prevalence of oral mucosal lesions was more common in patients who were classified at baseline as Centers for Disease Control (CDC) C3 category than CDC A2, A3, B2, and B3 (<i>P</i> < 0.05). An overall prevalence of 1.98% was observed for oral Kaposi’s sarcoma. Additionally, the HIV group on HAART (0.37 ± 0.23 mL/min) had significantly lower salivary flow rates (<i>P</i> < 0.01) compared with the healthy group (0.49 ± 0.15 mL/min).</p><p><b>Conclusions: </b> Although HAART appears to markedly reduce the prevalence of oral mucosal lesions during the course of HIV disease, regular systematic oral screening is still warranted for such populations for the early diagnosis and management of pathologies, such as Kaposi’s sarcoma.</p></abstract></abstractGroup></contentMeta><noteGroup><note xml:id="artCateg-note" numbered="no"><p>Oral Medicine</p></note></noteGroup></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Prevalence of oral mucosal lesions in adults undergoing highly active antiretroviral therapy in Hong Kong</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Highly active antiretroviral therapy</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Prevalence of oral mucosal lesions in adults undergoing highly active antiretroviral therapy in Hong Kong</title></titleInfo><name type="personal"><namePart type="given">Mahendra</namePart><namePart type="family">Perera</namePart><affiliation> Faculty of Dentistry, University of Hong Kong, Hong Kong, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Peter Chiu Shun</namePart><namePart type="family">Tsang</namePart><affiliation> Faculty of Dentistry, University of Hong Kong, Hong Kong, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Lakshman</namePart><namePart type="family">Samaranayake</namePart><affiliation> Faculty of Dentistry, University of Hong Kong, Hong Kong, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Man Po</namePart><namePart type="family">Lee</namePart><affiliation> AIDS Clinical Service, Queen Elizabeth Hospital, Hong Kong, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Patrick</namePart><namePart type="family">Li</namePart><affiliation> AIDS Clinical Service, Queen Elizabeth Hospital, Hong Kong, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">2012-08</dateIssued><edition>Received 21 December 2011; accepted 7 January 2012.</edition><copyrightDate encoding="w3cdtf">2012</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="figures">1</extent><extent unit="tables">4</extent></physicalDescription><abstract>Aim: Highly active antiretroviral therapy (HAART) has altered the prevalence and incidence of oral mucosal lesions of HIV infection. Recent reports show a variation in the prevalence of oral mucosal lesions in different population groups. Understanding the prevalence of these lesions is of paramount importance in the efficient delivery of dental care to such cohorts. The aim of the present study was to investigate the prevalence of oral mucosal lesions and salivary parameters during HAART in an ethnic Chinese cohort in Hong Kong.</abstract><abstract>Methods: A cross‐sectional estimation of the prevalence of oral mucosal lesions was carried out in 101 HIV‐infected ethnic Chinese in Hong Kong using the European Community–Clearinghouse classification.</abstract><abstract>Results: The prevalence of oral mucosal lesions was more common in patients who were classified at baseline as Centers for Disease Control (CDC) C3 category than CDC A2, A3, B2, and B3 (P < 0.05). An overall prevalence of 1.98% was observed for oral Kaposi’s sarcoma. Additionally, the HIV group on HAART (0.37 ± 0.23 mL/min) had significantly lower salivary flow rates (P < 0.01) compared with the healthy group (0.49 ± 0.15 mL/min).</abstract><abstract>Conclusions: Although HAART appears to markedly reduce the prevalence of oral mucosal lesions during the course of HIV disease, regular systematic oral screening is still warranted for such populations for the early diagnosis and management of pathologies, such as Kaposi’s sarcoma.</abstract><subject lang="en"><genre>keywords</genre><topic>highly active antiretroviral therapy</topic><topic>Hong Kong</topic><topic>human immunodeficiency virus</topic><topic>infection</topic><topic>oral mucosal lesion</topic></subject><relatedItem type="host"><titleInfo><title>Journal of Investigative and Clinical Dentistry</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><subject><genre>article-category</genre><topic>ORIGINAL ARTICLE</topic></subject><identifier type="ISSN">2041-1618</identifier><identifier type="eISSN">2041-1626</identifier><identifier type="DOI">10.1111/(ISSN)2041-1626</identifier><identifier type="PublisherID">JICD</identifier><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>3</number></detail><detail type="issue"><caption>no.</caption><number>3</number></detail><extent unit="pages"><start>208</start><end>214</end><total>7</total></extent></part></relatedItem><identifier type="istex">13256BD6AB95B1D4522B6088E9A9350480871299</identifier><identifier type="ark">ark:/67375/WNG-78S8KKC7-T</identifier><identifier type="DOI">10.1111/j.2041-1626.2012.00124.x</identifier><identifier type="ArticleID">JICD124</identifier><accessCondition type="use and reproduction" contentType="copyright">© 2012 Blackwell Publishing Asia Pty Ltd</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-L0C46X92-X">wiley</recordContentSource><recordOrigin>Blackwell Publishing Ltd</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/document/13256BD6AB95B1D4522B6088E9A9350480871299/metadata/json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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