Tissue reactions to subperiosteal onlays of demineralized xenogenous dentin blocks in rats
Identifieur interne : 000363 ( Istex/Corpus ); précédent : 000362; suivant : 000364Tissue reactions to subperiosteal onlays of demineralized xenogenous dentin blocks in rats
Auteurs : Arne Mordenfeld ; Mats Hallman ; Sven LindskogSource :
- Dental Traumatology [ 1600-4469 ] ; 2011-12.
English descriptors
- KwdEn :
- Bone formation, Bone induction, Demineralization, Demineralized, Demineralized bone, Demineralized dentin, Dentin, Dentin block, Dentin block demineralized, Dentin blocks, Dentin onlays, Edta, Encapsulation, Graft, Healing period, Implant, Implant surface, Important role, Infection control, Intense sites, John wiley sons, John wiley sons demineralized dentin implants, Matrix, Maxillofac, Onlay, Onlay demineralized, Onlays, Oral maxillofac implants, Oral maxillofac surg, Osseous integration, Osteoconductive, Osteoconductive environment, Osteogenic properties, Osteoinductive, Pairwise, Pairwise comparisons, Partial demineralization, Possible mass, Present study, Resorption, Right side, Subperiosteal, Subperiosteal dissection, Surg, Urist, Wilcoxon rank, Xenogenous, Xenogenous dentin onlays.
- Teeft :
- Bone formation, Bone induction, Demineralization, Demineralized, Demineralized bone, Demineralized dentin, Dentin, Dentin block, Dentin block demineralized, Dentin blocks, Dentin onlays, Edta, Encapsulation, Graft, Healing period, Implant, Implant surface, Important role, Infection control, Intense sites, John wiley sons, John wiley sons demineralized dentin implants, Matrix, Maxillofac, Onlay, Onlay demineralized, Onlays, Oral maxillofac implants, Oral maxillofac surg, Osseous integration, Osteoconductive, Osteoconductive environment, Osteogenic properties, Osteoinductive, Pairwise, Pairwise comparisons, Partial demineralization, Possible mass, Present study, Resorption, Right side, Subperiosteal, Subperiosteal dissection, Surg, Urist, Wilcoxon rank, Xenogenous, Xenogenous dentin onlays.
Abstract
Abstract – Objectives:
Url:
DOI: 10.1111/j.1600-9657.2011.01026.x
Links to Exploration step
ISTEX:076FC4C759F3D63D779BEF65DD4578C23A857EE9Le document en format XML
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Oral & Maxillofacial Surgery, Public Health Service, Gävle</mods:affiliation></affiliation><affiliation><mods:affiliation>Center for Research and Development, Uppsala University/Gävleborg County Council, Gävleborg</mods:affiliation></affiliation></author><author><name sortKey="Lindskog, Sven" sort="Lindskog, Sven" uniqKey="Lindskog S" first="Sven" last="Lindskog">Sven Lindskog</name><affiliation><mods:affiliation>Department of Pathology and Cytology, Karolinska University Hospital, Stockholm, Sweden</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Dental Traumatology</title><title level="j" type="alt">DENTAL TRAUMATOLOGY</title><idno type="ISSN">1600-4469</idno><idno type="eISSN">1600-9657</idno><imprint><biblScope unit="vol">27</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="446">446</biblScope><biblScope unit="page" to="451">451</biblScope><biblScope 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implants</term><term>Matrix</term><term>Maxillofac</term><term>Onlay</term><term>Onlay demineralized</term><term>Onlays</term><term>Oral maxillofac implants</term><term>Oral maxillofac surg</term><term>Osseous integration</term><term>Osteoconductive</term><term>Osteoconductive environment</term><term>Osteogenic properties</term><term>Osteoinductive</term><term>Pairwise</term><term>Pairwise comparisons</term><term>Partial demineralization</term><term>Possible mass</term><term>Present study</term><term>Resorption</term><term>Right side</term><term>Subperiosteal</term><term>Subperiosteal dissection</term><term>Surg</term><term>Urist</term><term>Wilcoxon rank</term><term>Xenogenous</term><term>Xenogenous dentin onlays</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Bone formation</term><term>Bone induction</term><term>Demineralization</term><term>Demineralized</term><term>Demineralized bone</term><term>Demineralized dentin</term><term>Dentin</term><term>Dentin block</term><term>Dentin block demineralized</term><term>Dentin blocks</term><term>Dentin onlays</term><term>Edta</term><term>Encapsulation</term><term>Graft</term><term>Healing period</term><term>Implant</term><term>Implant surface</term><term>Important role</term><term>Infection control</term><term>Intense sites</term><term>John wiley sons</term><term>John wiley sons demineralized dentin implants</term><term>Matrix</term><term>Maxillofac</term><term>Onlay</term><term>Onlay demineralized</term><term>Onlays</term><term>Oral maxillofac implants</term><term>Oral maxillofac surg</term><term>Osseous integration</term><term>Osteoconductive</term><term>Osteoconductive environment</term><term>Osteogenic properties</term><term>Osteoinductive</term><term>Pairwise</term><term>Pairwise comparisons</term><term>Partial demineralization</term><term>Possible mass</term><term>Present study</term><term>Resorption</term><term>Right side</term><term>Subperiosteal</term><term>Subperiosteal dissection</term><term>Surg</term><term>Urist</term><term>Wilcoxon rank</term><term>Xenogenous</term><term>Xenogenous dentin onlays</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract">Abstract – Objectives: </div></front></TEI><istex><corpusName>wiley</corpusName><keywords><teeft><json:string>dentin</json:string><json:string>demineralized</json:string><json:string>bone formation</json:string><json:string>resorption</json:string><json:string>edta</json:string><json:string>onlays</json:string><json:string>xenogenous</json:string><json:string>demineralization</json:string><json:string>osteoconductive</json:string><json:string>dentin blocks</json:string><json:string>osteoconductive environment</json:string><json:string>surg</json:string><json:string>onlay</json:string><json:string>implant</json:string><json:string>graft</json:string><json:string>right 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integration</json:string><json:string>john wiley sons</json:string><json:string>implant surface</json:string><json:string>healing period</json:string><json:string>present study</json:string><json:string>possible mass</json:string><json:string>bone induction</json:string><json:string>infection control</json:string><json:string>oral maxillofac implants</json:string><json:string>demineralized bone</json:string><json:string>osteogenic properties</json:string></teeft></keywords><author><json:item><name>Arne Mordenfeld</name><affiliations><json:string>Department of Oral & Maxillofacial Surgery, Public Health Service, Gävle</json:string><json:string>Center for Research and Development, Uppsala University/Gävleborg County Council, Gävleborg</json:string><json:string>Department of Biomaterials/Handicap Research, Institute for Surgical Sciences, Göteborg University, Göteborg</json:string></affiliations></json:item><json:item><name>Mats Hallman</name><affiliations><json:string>Department of Oral & Maxillofacial Surgery, Public Health Service, Gävle</json:string><json:string>Center for Research and Development, Uppsala University/Gävleborg County Council, Gävleborg</json:string></affiliations></json:item><json:item><name>Sven Lindskog</name><affiliations><json:string>Department of Pathology and Cytology, Karolinska University Hospital, Stockholm, Sweden</json:string></affiliations></json:item></author><articleId><json:string>EDT1026</json:string></articleId><arkIstex>ark:/67375/WNG-KT6X6WW5-Q</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>Abstract – Objectives:</abstract><qualityIndicators><refBibsNative>true</refBibsNative><abstractWordCount>2</abstractWordCount><abstractCharCount>24</abstractCharCount><keywordCount>0</keywordCount><score>5.762</score><pdfWordCount>3738</pdfWordCount><pdfCharCount>24731</pdfCharCount><pdfVersion>1.3</pdfVersion><pdfPageCount>6</pdfPageCount><pdfPageSize>595.276 x 802.205 pts</pdfPageSize></qualityIndicators><title>Tissue reactions to subperiosteal onlays of demineralized xenogenous dentin blocks in rats</title><pmid><json:string>21707920</json:string></pmid><genre><json:string>article</json:string></genre><host><title>Dental 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Oral</json:string></orgName><orgName_funder></orgName_funder><orgName_provider></orgName_provider><persName><json:string>John Wiley</json:string><json:string>Sven Lindskog</json:string><json:string>Arne Mordenfeld</json:string><json:string>Janssen Pharmaceutica</json:string></persName><placeName><json:string>Belgium</json:string></placeName><ref_url></ref_url><ref_bibl><json:string>Mordenfeld et al.</json:string><json:string>Machado et al.</json:string></ref_bibl><bibl></bibl></unitex></namedEntities><ark><json:string>ark:/67375/WNG-KT6X6WW5-Q</json:string></ark><categories><wos><json:string>1 - science</json:string><json:string>2 - dentistry, oral surgery & medicine</json:string></wos><scienceMetrix><json:string>1 - health sciences</json:string><json:string>2 - clinical medicine</json:string><json:string>3 - dentistry</json:string></scienceMetrix><scopus><json:string>1 - Health Sciences</json:string><json:string>2 - Dentistry</json:string><json:string>3 - Oral Surgery</json:string></scopus></categories><publicationDate>2011</publicationDate><copyrightDate>2011</copyrightDate><doi><json:string>10.1111/j.1600-9657.2011.01026.x</json:string></doi><id>076FC4C759F3D63D779BEF65DD4578C23A857EE9</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/076FC4C759F3D63D779BEF65DD4578C23A857EE9/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/076FC4C759F3D63D779BEF65DD4578C23A857EE9/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/076FC4C759F3D63D779BEF65DD4578C23A857EE9/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main">Tissue reactions to subperiosteal onlays of demineralized xenogenous dentin blocks in rats</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><availability><licence>© 2011 John Wiley & Sons A/S</licence></availability><date type="published" when="2011-12"></date></publicationStmt><notesStmt><note type="content-type" subtype="article" source="article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="article"><analytic><title level="a" type="main">Tissue reactions to subperiosteal onlays of demineralized xenogenous dentin blocks in rats</title><title level="a" type="short">Demineralized dentin implants</title><author xml:id="author-0000"><persName><forename type="first">Arne</forename><surname>Mordenfeld</surname></persName><affiliation>Department of Oral & Maxillofacial Surgery, Public Health Service, Gävle</affiliation><affiliation>Center for Research and Development, Uppsala University/Gävleborg County Council, Gävleborg</affiliation><affiliation>Department of Biomaterials/Handicap Research, Institute for Surgical Sciences, Göteborg University, Göteborg</affiliation></author><author xml:id="author-0001"><persName><forename type="first">Mats</forename><surname>Hallman</surname></persName><affiliation>Department of Oral & Maxillofacial Surgery, Public Health Service, Gävle</affiliation><affiliation>Center for Research and Development, Uppsala University/Gävleborg County Council, Gävleborg</affiliation></author><author xml:id="author-0002"><persName><forename type="first">Sven</forename><surname>Lindskog</surname></persName><affiliation>Department of Pathology and Cytology, Karolinska University Hospital, Stockholm, Sweden<address><country key="SE"></country></address></affiliation></author><idno type="istex">076FC4C759F3D63D779BEF65DD4578C23A857EE9</idno><idno type="ark">ark:/67375/WNG-KT6X6WW5-Q</idno><idno type="DOI">10.1111/j.1600-9657.2011.01026.x</idno><idno type="unit">EDT1026</idno><idno type="toTypesetVersion">file:EDT.EDT1026.pdf</idno></analytic><monogr><title level="j" type="main">Dental Traumatology</title><title level="j" type="alt">DENTAL TRAUMATOLOGY</title><idno type="pISSN">1600-4469</idno><idno type="eISSN">1600-9657</idno><idno type="book-DOI">10.1111/(ISSN)1600-9657</idno><idno type="book-part-DOI">10.1111/edt.2011.27.issue-6</idno><idno type="product">EDT</idno><idno type="publisherDivision">ST</idno><imprint><biblScope unit="vol">27</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="446">446</biblScope><biblScope unit="page" to="451">451</biblScope><biblScope unit="page-count">6</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2011-12"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><abstract xml:lang="en" style="main"><p><hi rend="bold">Abstract – </hi>
<hi rend="italic">Objectives: </hi></p><p>This study was undertaken to examine the influence of partial demineralization of xenogenous dentin on bone formation in an osteoconductive environment.</p><p><hi rend="italic">Materials and methods: </hi></p><p>Sixty dentin blocks, 2–3 mm thick and 4 mm in diameter, were prepared from developing teeth of young pigs. Forty blocks were demineralized in 24% ethylenediaminetetraacetic acid (pH 7.0) for 1, 2, 6 or 12 h. Forty adult rats divided into eight groups with five rats in each group were used. A sagittal midcranial incision was made from the occipital to the frontal region. Through a subperiostal dissection, a pocket was created on each side of the skull. One demineralized block was placed on one side, and a non‐demineralized block was placed on the contralateral side, or the pocket was left empty as controls. Thus, eight experimental groups with five rats in each were formed.</p><p><hi rend="italic">Results: </hi></p><p>Resorption increased significantly with increasing degree of demineralization while bone formation increased significantly with increasing degree of demineralization, provided inflammation was compensated for. This suggests an important role for inflammation or infection control during the healing period of osteogenic implants to optimize osseous integration in an osteoconductive environment.</p><p><hi rend="italic">Conclusion: </hi></p><p>Partial demineralization of xenogenous dentin blocks may provide a method for optimizing the integration of dentin onlays in an osteoconductive environment, thus stabilizing the implant and slowing down replacement resorption.</p></abstract><textClass><keywords rend="tocHeading1"><term>ORIGINAL ARTICLES</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/076FC4C759F3D63D779BEF65DD4578C23A857EE9/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Publishing Ltd</publisherName><publisherLoc>Oxford, UK</publisherLoc></publisherInfo><doi origin="wiley" registered="yes">10.1111/(ISSN)1600-9657</doi><issn type="print">1600-4469</issn><issn type="electronic">1600-9657</issn><idGroup><id type="product" value="EDT"></id><id type="publisherDivision" value="ST"></id></idGroup><titleGroup><title type="main" sort="DENTAL TRAUMATOLOGY">Dental Traumatology</title></titleGroup></publicationMeta><publicationMeta level="part" position="12106"><doi origin="wiley">10.1111/edt.2011.27.issue-6</doi><numberingGroup><numbering type="journalVolume" number="27">27</numbering><numbering type="journalIssue" number="6">6</numbering></numberingGroup><coverDate startDate="2011-12">December 2011</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="7" status="forIssue"><doi origin="wiley">10.1111/j.1600-9657.2011.01026.x</doi><idGroup><id type="unit" value="EDT1026"></id></idGroup><countGroup><count type="pageTotal" number="6"></count></countGroup><titleGroup><title type="tocHeading1">ORIGINAL ARTICLES</title></titleGroup><copyright>© 2011 John Wiley & Sons A/S</copyright><eventGroup><event type="xmlConverted" agent="Converter:BPG_TO_WML3G version:2.10 mode:FullText" date="2011-11-11"></event><event type="publishedOnlineEarlyUnpaginated" date="2011-06-26"></event><event type="firstOnline" date="2011-06-26"></event><event type="publishedOnlineFinalForm" date="2011-11-11"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-20"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-16"></event></eventGroup><numberingGroup><numbering type="pageFirst" number="446">446</numbering><numbering type="pageLast" number="451">451</numbering></numberingGroup><correspondenceTo>Dr Arne Mordenfeld, Department of Oral & Maxillofacial Surgery, Public Health Service, Gävle Hospital, S‐801 87 Gävle, Sweden
Tel.: +46 26 155646
Fax: +46 26 155347
e‐mails: <email>arne.mordenfeld@lg.se</email>; <email>christine_berthold@yahoo.de</email></correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:EDT.EDT1026.pdf"></link></linkGroup></publicationMeta><contentMeta><unparsedEditorialHistory>Accepted 29 April, 2011</unparsedEditorialHistory><countGroup><count type="figureTotal" number="4"></count><count type="tableTotal" number="3"></count></countGroup><titleGroup><title type="main">Tissue reactions to subperiosteal onlays of demineralized xenogenous dentin blocks in rats</title><title type="shortAuthors"><i>Mordenfeld et al.</i></title><title type="short"><i>Demineralized dentin implants</i></title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#a1 #a2 #a3"><personName><givenNames>Arne</givenNames><familyName>Mordenfeld</familyName></personName></creator><creator creatorRole="author" xml:id="cr2" affiliationRef="#a1 #a2"><personName><givenNames>Mats</givenNames><familyName>Hallman</familyName></personName></creator><creator creatorRole="author" xml:id="cr3" affiliationRef="#a4"><personName><givenNames>Sven</givenNames><familyName>Lindskog</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="a1"><unparsedAffiliation>Department of Oral & Maxillofacial Surgery, Public Health Service, Gävle</unparsedAffiliation></affiliation><affiliation xml:id="a2"><unparsedAffiliation>Center for Research and Development, Uppsala University/Gävleborg County Council, Gävleborg</unparsedAffiliation></affiliation><affiliation xml:id="a3"><unparsedAffiliation>Department of Biomaterials/Handicap Research, Institute for Surgical Sciences, Göteborg University, Göteborg</unparsedAffiliation></affiliation><affiliation xml:id="a4" countryCode="SE"><unparsedAffiliation>Department of Pathology and Cytology, Karolinska University Hospital, Stockholm, Sweden</unparsedAffiliation></affiliation></affiliationGroup><abstractGroup><abstract type="main" xml:lang="en"><p><b>Abstract – </b> <i>Objectives: </i></p><p>This study was undertaken to examine the influence of partial demineralization of xenogenous dentin on bone formation in an osteoconductive environment.</p><p><i>Materials and methods: </i></p><p>Sixty dentin blocks, 2–3 mm thick and 4 mm in diameter, were prepared from developing teeth of young pigs. Forty blocks were demineralized in 24% ethylenediaminetetraacetic acid (pH 7.0) for 1, 2, 6 or 12 h. Forty adult rats divided into eight groups with five rats in each group were used. A sagittal midcranial incision was made from the occipital to the frontal region. Through a subperiostal dissection, a pocket was created on each side of the skull. One demineralized block was placed on one side, and a non‐demineralized block was placed on the contralateral side, or the pocket was left empty as controls. Thus, eight experimental groups with five rats in each were formed.</p><p><i>Results: </i></p><p>Resorption increased significantly with increasing degree of demineralization while bone formation increased significantly with increasing degree of demineralization, provided inflammation was compensated for. This suggests an important role for inflammation or infection control during the healing period of osteogenic implants to optimize osseous integration in an osteoconductive environment.</p><p><i>Conclusion: </i></p><p>Partial demineralization of xenogenous dentin blocks may provide a method for optimizing the integration of dentin onlays in an osteoconductive environment, thus stabilizing the implant and slowing down replacement resorption.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Tissue reactions to subperiosteal onlays of demineralized xenogenous dentin blocks in rats</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Demineralized dentin implants</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Tissue reactions to subperiosteal onlays of demineralized xenogenous dentin blocks in rats</title></titleInfo><name type="personal"><namePart type="given">Arne</namePart><namePart type="family">Mordenfeld</namePart><affiliation>Department of Oral & Maxillofacial Surgery, Public Health Service, Gävle</affiliation><affiliation>Center for Research and Development, Uppsala University/Gävleborg County Council, Gävleborg</affiliation><affiliation>Department of Biomaterials/Handicap Research, Institute for Surgical Sciences, Göteborg University, Göteborg</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Mats</namePart><namePart type="family">Hallman</namePart><affiliation>Department of Oral & Maxillofacial Surgery, Public Health Service, Gävle</affiliation><affiliation>Center for Research and Development, Uppsala University/Gävleborg County Council, Gävleborg</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Sven</namePart><namePart type="family">Lindskog</namePart><affiliation>Department of Pathology and Cytology, Karolinska University Hospital, Stockholm, Sweden</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">2011-12</dateIssued><edition>Accepted 29 April, 2011</edition><copyrightDate encoding="w3cdtf">2011</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="figures">4</extent><extent unit="tables">3</extent></physicalDescription><abstract>Abstract – Objectives: </abstract><abstract>This study was undertaken to examine the influence of partial demineralization of xenogenous dentin on bone formation in an osteoconductive environment.</abstract><abstract>Materials and methods: </abstract><abstract>Sixty dentin blocks, 2–3 mm thick and 4 mm in diameter, were prepared from developing teeth of young pigs. Forty blocks were demineralized in 24% ethylenediaminetetraacetic acid (pH 7.0) for 1, 2, 6 or 12 h. Forty adult rats divided into eight groups with five rats in each group were used. A sagittal midcranial incision was made from the occipital to the frontal region. Through a subperiostal dissection, a pocket was created on each side of the skull. One demineralized block was placed on one side, and a non‐demineralized block was placed on the contralateral side, or the pocket was left empty as controls. Thus, eight experimental groups with five rats in each were formed.</abstract><abstract>Results: </abstract><abstract>Resorption increased significantly with increasing degree of demineralization while bone formation increased significantly with increasing degree of demineralization, provided inflammation was compensated for. This suggests an important role for inflammation or infection control during the healing period of osteogenic implants to optimize osseous integration in an osteoconductive environment.</abstract><abstract>Conclusion: </abstract><abstract>Partial demineralization of xenogenous dentin blocks may provide a method for optimizing the integration of dentin onlays in an osteoconductive environment, thus stabilizing the implant and slowing down replacement resorption.</abstract><relatedItem type="host"><titleInfo><title>Dental Traumatology</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><identifier type="ISSN">1600-4469</identifier><identifier type="eISSN">1600-9657</identifier><identifier type="DOI">10.1111/(ISSN)1600-9657</identifier><identifier type="PublisherID">EDT</identifier><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>27</number></detail><detail type="issue"><caption>no.</caption><number>6</number></detail><extent unit="pages"><start>446</start><end>451</end><total>6</total></extent></part></relatedItem><identifier type="istex">076FC4C759F3D63D779BEF65DD4578C23A857EE9</identifier><identifier type="ark">ark:/67375/WNG-KT6X6WW5-Q</identifier><identifier type="DOI">10.1111/j.1600-9657.2011.01026.x</identifier><identifier type="ArticleID">EDT1026</identifier><accessCondition type="use and reproduction" contentType="copyright">© 2011 John Wiley & Sons A/S</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-L0C46X92-X">wiley</recordContentSource><recordOrigin>Blackwell Publishing Ltd</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/document/076FC4C759F3D63D779BEF65DD4578C23A857EE9/metadata/json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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