Molecular events associated with ciclosporin A‐induced gingival overgrowth are attenuated by Smad7 overexpression in fibroblasts
Identifieur interne : 000E24 ( Istex/Checkpoint ); précédent : 000E23; suivant : 000E25Molecular events associated with ciclosporin A‐induced gingival overgrowth are attenuated by Smad7 overexpression in fibroblasts
Auteurs : L. M. Sobral [Brésil] ; F. Aseredo [Brésil] ; M. Agostini [Brésil] ; A. Bufalino [Brésil] ; M. C. C. Pereira [Brésil] ; E. Graner [Brésil] ; R. D. Coletta [Brésil]Source :
- Journal of Periodontal Research [ 0022-3484 ] ; 2012-04.
English descriptors
- KwdEn :
- Apoptosis, Assay, Autocrine, Broblast, Broblast proliferation, Broblasts, Cancer progression, Cell cycle, Cell cycle analysis, Cell line, Ciclosporin, Ciclosporin gingival overgrowth, Coletta, Collagen, Collagen production, Collagen synthesis, Control cells, Culture supernatants, Cyclosporin, Cyclosporine, Densitometric analysis, Extracellular, Extracellular matrix, Fibroblast, Gingiva, Gingival, Gingival enlargement, Gingival fibroblasts, Gingival overgrowth, Graner, Hereditary gingival fibromatosis, High levels, Human gingival fibroblasts, Matrix, Molecular events, Normal gingiva, Overexpression, Overgrowth, Periodontal, Periodontol, Phosphorylation, Proliferation, Psmad2, Renal injury, Smad2, Smad2 phosphorylation, Smad7, Smad7 overexpression, Sobral, Untreated cells.
- Teeft :
- Apoptosis, Assay, Autocrine, Broblast, Broblast proliferation, Broblasts, Cancer progression, Cell cycle, Cell cycle analysis, Cell line, Ciclosporin, Ciclosporin gingival overgrowth, Coletta, Collagen, Collagen production, Collagen synthesis, Control cells, Culture supernatants, Cyclosporin, Cyclosporine, Densitometric analysis, Extracellular, Extracellular matrix, Fibroblast, Gingiva, Gingival, Gingival enlargement, Gingival fibroblasts, Gingival overgrowth, Graner, Hereditary gingival fibromatosis, High levels, Human gingival fibroblasts, Matrix, Molecular events, Normal gingiva, Overexpression, Overgrowth, Periodontal, Periodontol, Phosphorylation, Proliferation, Psmad2, Renal injury, Smad2, Smad2 phosphorylation, Smad7, Smad7 overexpression, Sobral, Untreated cells.
Abstract
Sobral LM, Aseredo F, Agostini M, Bufalino A, Pereira MCC, Graner E, Coletta RD. Molecular events associated with ciclosporin A‐induced gingival overgrowth are attenuated by Smad7 overexpression in fibroblasts. J Periodont Res 2012; 47: 149–158. © 2011 John Wiley & Sons A/S
Url:
DOI: 10.1111/j.1600-0765.2011.01412.x
Affiliations:
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ISTEX:12AF945297E6D4AA11F8C68C8BCEF2F8907678C1Le document en format XML
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Apoptosis</term>
<term>Assay</term>
<term>Autocrine</term>
<term>Broblast</term>
<term>Broblast proliferation</term>
<term>Broblasts</term>
<term>Cancer progression</term>
<term>Cell cycle</term>
<term>Cell cycle analysis</term>
<term>Cell line</term>
<term>Ciclosporin</term>
<term>Ciclosporin gingival overgrowth</term>
<term>Coletta</term>
<term>Collagen</term>
<term>Collagen production</term>
<term>Collagen synthesis</term>
<term>Control cells</term>
<term>Culture supernatants</term>
<term>Cyclosporin</term>
<term>Cyclosporine</term>
<term>Densitometric analysis</term>
<term>Extracellular</term>
<term>Extracellular matrix</term>
<term>Fibroblast</term>
<term>Gingiva</term>
<term>Gingival</term>
<term>Gingival enlargement</term>
<term>Gingival fibroblasts</term>
<term>Gingival overgrowth</term>
<term>Graner</term>
<term>Hereditary gingival fibromatosis</term>
<term>High levels</term>
<term>Human gingival fibroblasts</term>
<term>Matrix</term>
<term>Molecular events</term>
<term>Normal gingiva</term>
<term>Overexpression</term>
<term>Overgrowth</term>
<term>Periodontal</term>
<term>Periodontol</term>
<term>Phosphorylation</term>
<term>Proliferation</term>
<term>Psmad2</term>
<term>Renal injury</term>
<term>Smad2</term>
<term>Smad2 phosphorylation</term>
<term>Smad7</term>
<term>Smad7 overexpression</term>
<term>Sobral</term>
<term>Untreated cells</term>
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<keywords scheme="Teeft" xml:lang="en"><term>Apoptosis</term>
<term>Assay</term>
<term>Autocrine</term>
<term>Broblast</term>
<term>Broblast proliferation</term>
<term>Broblasts</term>
<term>Cancer progression</term>
<term>Cell cycle</term>
<term>Cell cycle analysis</term>
<term>Cell line</term>
<term>Ciclosporin</term>
<term>Ciclosporin gingival overgrowth</term>
<term>Coletta</term>
<term>Collagen</term>
<term>Collagen production</term>
<term>Collagen synthesis</term>
<term>Control cells</term>
<term>Culture supernatants</term>
<term>Cyclosporin</term>
<term>Cyclosporine</term>
<term>Densitometric analysis</term>
<term>Extracellular</term>
<term>Extracellular matrix</term>
<term>Fibroblast</term>
<term>Gingiva</term>
<term>Gingival</term>
<term>Gingival enlargement</term>
<term>Gingival fibroblasts</term>
<term>Gingival overgrowth</term>
<term>Graner</term>
<term>Hereditary gingival fibromatosis</term>
<term>High levels</term>
<term>Human gingival fibroblasts</term>
<term>Matrix</term>
<term>Molecular events</term>
<term>Normal gingiva</term>
<term>Overexpression</term>
<term>Overgrowth</term>
<term>Periodontal</term>
<term>Periodontol</term>
<term>Phosphorylation</term>
<term>Proliferation</term>
<term>Psmad2</term>
<term>Renal injury</term>
<term>Smad2</term>
<term>Smad2 phosphorylation</term>
<term>Smad7</term>
<term>Smad7 overexpression</term>
<term>Sobral</term>
<term>Untreated cells</term>
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<front><div type="abstract">Sobral LM, Aseredo F, Agostini M, Bufalino A, Pereira MCC, Graner E, Coletta RD. Molecular events associated with ciclosporin A‐induced gingival overgrowth are attenuated by Smad7 overexpression in fibroblasts. J Periodont Res 2012; 47: 149–158. © 2011 John Wiley & Sons A/S</div>
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<name sortKey="Aseredo, F" sort="Aseredo, F" uniqKey="Aseredo F" first="F." last="Aseredo">F. Aseredo</name>
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<name sortKey="Graner, E" sort="Graner, E" uniqKey="Graner E" first="E." last="Graner">E. Graner</name>
<name sortKey="Pereira, M C C" sort="Pereira, M C C" uniqKey="Pereira M" first="M. C. C." last="Pereira">M. C. C. Pereira</name>
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