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Bone-healing pattern at the surface of titanium implants: an experimental study in the dog.

Identifieur interne : 000292 ( PubMed/Corpus ); précédent : 000291; suivant : 000293

Bone-healing pattern at the surface of titanium implants: an experimental study in the dog.

Auteurs : Fabio Rossi ; Niklaus P. Lang ; Enzo De Santis ; Fabrizio Morelli ; Giovanni Favero ; Daniele Botticelli

Source :

RBID : pubmed:23289845

English descriptors

Abstract

To study the early sequential stages of osseointegration at implants installed in alveolar bony.

DOI: 10.1111/clr.12097
PubMed: 23289845

Links to Exploration step

pubmed:23289845

Le document en format XML

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<title xml:lang="en">Bone-healing pattern at the surface of titanium implants: an experimental study in the dog.</title>
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<name sortKey="Rossi, Fabio" sort="Rossi, Fabio" uniqKey="Rossi F" first="Fabio" last="Rossi">Fabio Rossi</name>
<affiliation>
<nlm:affiliation>Department of Biomedical and Neuromotor Sciences University of Bologna, Bologna, Italy.</nlm:affiliation>
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<author>
<name sortKey="Lang, Niklaus P" sort="Lang, Niklaus P" uniqKey="Lang N" first="Niklaus P" last="Lang">Niklaus P. Lang</name>
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<author>
<name sortKey="De Santis, Enzo" sort="De Santis, Enzo" uniqKey="De Santis E" first="Enzo" last="De Santis">Enzo De Santis</name>
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<author>
<name sortKey="Morelli, Fabrizio" sort="Morelli, Fabrizio" uniqKey="Morelli F" first="Fabrizio" last="Morelli">Fabrizio Morelli</name>
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<author>
<name sortKey="Favero, Giovanni" sort="Favero, Giovanni" uniqKey="Favero G" first="Giovanni" last="Favero">Giovanni Favero</name>
</author>
<author>
<name sortKey="Botticelli, Daniele" sort="Botticelli, Daniele" uniqKey="Botticelli D" first="Daniele" last="Botticelli">Daniele Botticelli</name>
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<title xml:lang="en">Bone-healing pattern at the surface of titanium implants: an experimental study in the dog.</title>
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<name sortKey="Rossi, Fabio" sort="Rossi, Fabio" uniqKey="Rossi F" first="Fabio" last="Rossi">Fabio Rossi</name>
<affiliation>
<nlm:affiliation>Department of Biomedical and Neuromotor Sciences University of Bologna, Bologna, Italy.</nlm:affiliation>
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<author>
<name sortKey="Lang, Niklaus P" sort="Lang, Niklaus P" uniqKey="Lang N" first="Niklaus P" last="Lang">Niklaus P. Lang</name>
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<author>
<name sortKey="De Santis, Enzo" sort="De Santis, Enzo" uniqKey="De Santis E" first="Enzo" last="De Santis">Enzo De Santis</name>
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<author>
<name sortKey="Morelli, Fabrizio" sort="Morelli, Fabrizio" uniqKey="Morelli F" first="Fabrizio" last="Morelli">Fabrizio Morelli</name>
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<author>
<name sortKey="Favero, Giovanni" sort="Favero, Giovanni" uniqKey="Favero G" first="Giovanni" last="Favero">Giovanni Favero</name>
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<author>
<name sortKey="Botticelli, Daniele" sort="Botticelli, Daniele" uniqKey="Botticelli D" first="Daniele" last="Botticelli">Daniele Botticelli</name>
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<series>
<title level="j">Clinical oral implants research</title>
<idno type="eISSN">1600-0501</idno>
<imprint>
<date when="2014" type="published">2014</date>
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<term>Animals</term>
<term>Dental Implantation, Endosseous (methods)</term>
<term>Dental Implants</term>
<term>Dogs</term>
<term>Implants, Experimental</term>
<term>Mandible (surgery)</term>
<term>Osseointegration</term>
<term>Surface Properties</term>
<term>Surgical Flaps</term>
<term>Titanium</term>
<term>Wound Healing</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en">
<term>Dental Implants</term>
<term>Titanium</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en">
<term>Dental Implantation, Endosseous</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en">
<term>Mandible</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Animals</term>
<term>Dogs</term>
<term>Implants, Experimental</term>
<term>Osseointegration</term>
<term>Surface Properties</term>
<term>Surgical Flaps</term>
<term>Wound Healing</term>
</keywords>
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<front>
<div type="abstract" xml:lang="en">To study the early sequential stages of osseointegration at implants installed in alveolar bony.</div>
</front>
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<PMID Version="1">23289845</PMID>
<DateCompleted>
<Year>2015</Year>
<Month>04</Month>
<Day>08</Day>
</DateCompleted>
<DateRevised>
<Year>2013</Year>
<Month>12</Month>
<Day>18</Day>
</DateRevised>
<Article PubModel="Print-Electronic">
<Journal>
<ISSN IssnType="Electronic">1600-0501</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>25</Volume>
<Issue>1</Issue>
<PubDate>
<Year>2014</Year>
<Month>Jan</Month>
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</JournalIssue>
<Title>Clinical oral implants research</Title>
<ISOAbbreviation>Clin Oral Implants Res</ISOAbbreviation>
</Journal>
<ArticleTitle>Bone-healing pattern at the surface of titanium implants: an experimental study in the dog.</ArticleTitle>
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<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To study the early sequential stages of osseointegration at implants installed in alveolar bony.</AbstractText>
<AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">In 12 Labrador dogs, all mandibular premolars and first molars were extracted bilaterally. After 3 months of healing, full-thickness flaps were elevated in the edentulous region of the right side of the mandible. Implants were installed, and the flaps were sutured to allow a fully submerged healing. The timing of the installations in the left side of the mandible and of sacrifices were performed with a schedule that various observation periods to sacrifice from 5, 10, 20, and 30 days were available so that n = 6 was obtained per each healing period. Ground sections were prepared and analyzed.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Newly formed bone in contact with the implant surface was found after 10 days of healing and the percentage increased up to 50% after 1 month of healing. A higher percentage was found in the trabecular compared with the cortical bony compartment. Old bone decreased by about 50% during healing, being still present after 1 month (16%). The proportions of bone debris and bone particles were at 27% after 5 days and decreased during healing to 6% after 1 month.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Osseointegration (new bone-to-implant contact) developed at various rates for cortical and trabecular compartments, respectively. In the trabecular region, mesenchymal cells were identified, subsequently developing into new bone in contact with the implant surface. In the cortical compartment, however, resorptive processes were observed throughout all periods of healing. The proportion of newly formed bone percentage was lower compared with that of the trabecular area. Old bone was still present after 1 month of healing in both compartments. Bone debris and small bone particles appeared to be involved in initial bone formation.</AbstractText>
<CopyrightInformation>© 2013 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd.</CopyrightInformation>
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<ForeName>Fabio</ForeName>
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<Affiliation>Department of Biomedical and Neuromotor Sciences University of Bologna, Bologna, Italy.</Affiliation>
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<Language>eng</Language>
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<DescriptorName UI="D008334" MajorTopicYN="N">Mandible</DescriptorName>
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<DescriptorName UI="D016348" MajorTopicYN="Y">Osseointegration</DescriptorName>
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<DescriptorName UI="D013499" MajorTopicYN="N">Surface Properties</DescriptorName>
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<DescriptorName UI="D013524" MajorTopicYN="N">Surgical Flaps</DescriptorName>
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<Keyword MajorTopicYN="N">animal study</Keyword>
<Keyword MajorTopicYN="N">bone</Keyword>
<Keyword MajorTopicYN="N">bone healing</Keyword>
<Keyword MajorTopicYN="N">early healing</Keyword>
<Keyword MajorTopicYN="N">histology</Keyword>
<Keyword MajorTopicYN="N">histometry</Keyword>
<Keyword MajorTopicYN="N">implant dentistry</Keyword>
<Keyword MajorTopicYN="N">osseointegration</Keyword>
<Keyword MajorTopicYN="N">submerged healing</Keyword>
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