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Intraosseous malignant peripheral nerve sheath tumor of maxilla: A case report with review of the literature

Identifieur interne : 000154 ( Pmc/Curation ); précédent : 000153; suivant : 000155

Intraosseous malignant peripheral nerve sheath tumor of maxilla: A case report with review of the literature

Auteurs : Sandhya Tamgadge [Inde] ; Neha Modak [Inde] ; Avinash P. Tamgadge [Inde] ; Sudhir Bhalerao [Inde]

Source :

RBID : PMC:4119377

Abstract

Malignant peripheral nerve sheath tumor (MPNST), the principle malignancy of peripheral nerve origin, though rare in the general population, occurs with excessive frequency among patients with neurofibromatosis. This tumor always arises in soft-tissues, usually found in the lower extremities and only 10-12% of all lesions occur in the head and neck region, which makes it a rare entity. The primary intraosseous MPNST is rare and has been reported most frequently in the mandible. This article discusses a case report of MPNST of the left maxilla without a history of benign nerve tissue tumor and the diagnostic difficulties associated with MPNST.


Url:
PubMed: 25097654
PubMed Central: 4119377

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PMC:4119377

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<journal-meta>
<journal-id journal-id-type="nlm-ta">Dent Res J (Isfahan)</journal-id>
<journal-id journal-id-type="iso-abbrev">Dent Res J (Isfahan)</journal-id>
<journal-id journal-id-type="publisher-id">DRJ</journal-id>
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<journal-title>Dental Research Journal</journal-title>
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<article-id pub-id-type="pmc">4119377</article-id>
<article-id pub-id-type="publisher-id">DRJ-11-405</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Case Report</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Intraosseous malignant peripheral nerve sheath tumor of maxilla: A case report with review of the literature</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Tamgadge</surname>
<given-names>Sandhya</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Modak</surname>
<given-names>Neha</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
<xref ref-type="corresp" rid="cor1"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Tamgadge</surname>
<given-names>Avinash P.</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Bhalerao</surname>
<given-names>Sudhir</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
</contrib-group>
<aff id="aff1">
<label>1</label>
Department of Oral and Maxillofacial Pathology and Microbiology, Padmashree Dr. D. Y. Patil Dental College and Hospital, Nerul, Navi Mumbai, Maharashtra, India</aff>
<author-notes>
<corresp id="cor1">
<bold>Address for correspondence:</bold>
Dr. Neha Modak, Department of Oral and Maxillofacial Pathology and Microbiology, Padmashree, Dr. D. Y. Patil Dental College and Hospital, Sector 7, Nerul, Navi Mumbai - 400 706, Maharashtra, India. E-mail:
<email xlink:href="nehamodak32@yahoo.com">nehamodak32@yahoo.com</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub">
<season>May-Jun</season>
<year>2014</year>
</pub-date>
<volume>11</volume>
<issue>3</issue>
<fpage>405</fpage>
<lpage>410</lpage>
<history>
<date date-type="received">
<month>11</month>
<year>2012</year>
</date>
<date date-type="accepted">
<month>6</month>
<year>2013</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright: © Dental Research Journal</copyright-statement>
<copyright-year>2014</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-sa/3.0">
<license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<abstract>
<p>Malignant peripheral nerve sheath tumor (MPNST), the principle malignancy of peripheral nerve origin, though rare in the general population, occurs with excessive frequency among patients with neurofibromatosis. This tumor always arises in soft-tissues, usually found in the lower extremities and only 10-12% of all lesions occur in the head and neck region, which makes it a rare entity. The primary intraosseous MPNST is rare and has been reported most frequently in the mandible. This article discusses a case report of MPNST of the left maxilla without a history of benign nerve tissue tumor and the diagnostic difficulties associated with MPNST.</p>
</abstract>
<kwd-group>
<kwd>
<italic>De novo</italic>
</kwd>
<kwd>intraosseous</kwd>
<kwd>malignant peripheral nerve sheath tumor</kwd>
<kwd>S-100</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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