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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The Canadian systemic sclerosis oral health study: orofacial manifestations and oral health-related quality of life in systemic sclerosis compared with the general population</title><author><name sortKey="Baron, Murray" sort="Baron, Murray" uniqKey="Baron M" first="Murray" last="Baron">Murray Baron</name><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, Department of Internal Medicine, SMBD Jewish General Hospital,</nlm:aff></affiliation><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, Faculty of Medicine, McGill University,</nlm:aff></affiliation></author><author><name sortKey="Hudson, Marie" sort="Hudson, Marie" uniqKey="Hudson M" first="Marie" last="Hudson">Marie Hudson</name><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, Department of Internal Medicine, SMBD Jewish General Hospital,</nlm:aff></affiliation><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, Faculty of Medicine, McGill University,</nlm:aff></affiliation></author><author><name sortKey="Tatibouet, Solene" sort="Tatibouet, Solene" uniqKey="Tatibouet S" first="Solène" last="Tatibouet">Solène Tatibouet</name><affiliation><nlm:aff id="ket441-AFF1">Epidemiology, Lady Davis Institute, SMBD Jewish General Hospital,</nlm:aff></affiliation></author><author><name sortKey="Steele, Russell" sort="Steele, Russell" uniqKey="Steele R" first="Russell" last="Steele">Russell Steele</name><affiliation><nlm:aff id="ket441-AFF1">Epidemiology, Lady Davis Institute, SMBD Jewish General Hospital,</nlm:aff></affiliation><affiliation><nlm:aff id="ket441-AFF1">Department of Mathematics and Statistics, McGill University, Montreal, Quebec,</nlm:aff></affiliation></author><author><name sortKey="Lo, Ernest" sort="Lo, Ernest" uniqKey="Lo E" first="Ernest" last="Lo">Ernest Lo</name><affiliation><nlm:aff id="ket441-AFF1">Epidemiology, Lady Davis Institute, SMBD Jewish General Hospital,</nlm:aff></affiliation></author><author><name sortKey="Gravel, Sabrina" sort="Gravel, Sabrina" uniqKey="Gravel S" first="Sabrina" last="Gravel">Sabrina Gravel</name><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, Department of Internal Medicine, SMBD Jewish General Hospital,</nlm:aff></affiliation></author><author><name sortKey="Gyger, Genevieve" sort="Gyger, Genevieve" uniqKey="Gyger G" first="Geneviève" last="Gyger">Geneviève Gyger</name><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, Department of Internal Medicine, SMBD Jewish General Hospital,</nlm:aff></affiliation><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, Faculty of Medicine, McGill University,</nlm:aff></affiliation></author><author><name sortKey="Sayegh, Tarek El" sort="Sayegh, Tarek El" uniqKey="Sayegh T" first="Tarek El" last="Sayegh">Tarek El Sayegh</name><affiliation><nlm:aff id="ket441-AFF1">School of Dentistry, University of Western Ontario,</nlm:aff></affiliation></author><author><name sortKey="Pope, Janet" sort="Pope, Janet" uniqKey="Pope J" first="Janet" last="Pope">Janet Pope</name><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, Department of Medicine, University of Western Ontario, London, Ontario,</nlm:aff></affiliation></author><author><name sortKey="Fontaine, Audrey" sort="Fontaine, Audrey" uniqKey="Fontaine A" first="Audrey" last="Fontaine">Audrey Fontaine</name><affiliation><nlm:aff id="ket441-AFF1">Department of Rheumatology, Université de Sherbrooke, Sherbrooke, Quebec,</nlm:aff></affiliation></author><author><name sortKey="Masseto, Ariel" sort="Masseto, Ariel" uniqKey="Masseto A" first="Ariel" last="Masseto">Ariel Masseto</name><affiliation><nlm:aff id="ket441-AFF1">Department of Rheumatology, Université de Sherbrooke, Sherbrooke, Quebec,</nlm:aff></affiliation></author><author><name sortKey="Matthews, Debora" sort="Matthews, Debora" uniqKey="Matthews D" first="Debora" last="Matthews">Debora Matthews</name><affiliation><nlm:aff id="ket441-AFF1">Department of Periodontology, Faculty of Dentistry,</nlm:aff></affiliation></author><author><name sortKey="Sutton, Evelyn" sort="Sutton, Evelyn" uniqKey="Sutton E" first="Evelyn" last="Sutton">Evelyn Sutton</name><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia,</nlm:aff></affiliation></author><author><name sortKey="Thie, Norman" sort="Thie, Norman" uniqKey="Thie N" first="Norman" last="Thie">Norman Thie</name><affiliation><nlm:aff id="ket441-AFF1">Division of Oro-facial Pain, School of Dentistry,</nlm:aff></affiliation></author><author><name sortKey="Jones, Niall" sort="Jones, Niall" uniqKey="Jones N" first="Niall" last="Jones">Niall Jones</name><affiliation><nlm:aff id="ket441-AFF1">Department of Medicine, University of Alberta, Edmonton, Alberta,</nlm:aff></affiliation></author><author><name sortKey="Copete, Maria" sort="Copete, Maria" uniqKey="Copete M" first="Maria" last="Copete">Maria Copete</name><affiliation><nlm:aff id="ket441-AFF1">Department of Pathology, College of Dentistry, University of Saskatchewan,</nlm:aff></affiliation></author><author><name sortKey="Kolbinson, Dean" sort="Kolbinson, Dean" uniqKey="Kolbinson D" first="Dean" last="Kolbinson">Dean Kolbinson</name><affiliation><nlm:aff id="ket441-AFF1">Department of Pathology, College of Dentistry, University of Saskatchewan,</nlm:aff></affiliation></author><author><name sortKey="Markland, Janet" sort="Markland, Janet" uniqKey="Markland J" first="Janet" last="Markland">Janet Markland</name><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan,</nlm:aff></affiliation></author><author><name sortKey="Nogueira Filho, Getulio" sort="Nogueira Filho, Getulio" uniqKey="Nogueira Filho G" first="Getulio" last="Nogueira-Filho">Getulio Nogueira-Filho</name><affiliation><nlm:aff id="ket441-AFF1">Department of Periodontology,</nlm:aff></affiliation></author><author><name sortKey="Robinson, David" sort="Robinson, David" uniqKey="Robinson D" first="David" last="Robinson">David Robinson</name><affiliation><nlm:aff wicri:cut=" and" id="ket441-AFF1">Rheumatology, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba</nlm:aff></affiliation></author><author><name sortKey="Gornitsky, Mervyn" sort="Gornitsky, Mervyn" uniqKey="Gornitsky M" first="Mervyn" last="Gornitsky">Mervyn Gornitsky</name><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, Faculty of Medicine, McGill University,</nlm:aff></affiliation><affiliation><nlm:aff id="ket441-AFF1">Department of Dentistry, SMBD Jewish General Hospital, Montreal, Quebec, Canada.</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24464709</idno><idno type="pmc">4103515</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103515</idno><idno type="RBID">PMC:4103515</idno><idno type="doi">10.1093/rheumatology/ket441</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">000371</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000371</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The Canadian systemic sclerosis oral health study: orofacial manifestations and oral health-related quality of life in systemic sclerosis compared with the general population</title><author><name sortKey="Baron, Murray" sort="Baron, Murray" uniqKey="Baron M" first="Murray" last="Baron">Murray Baron</name><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, Department of Internal Medicine, SMBD Jewish General Hospital,</nlm:aff></affiliation><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, Faculty of Medicine, McGill University,</nlm:aff></affiliation></author><author><name sortKey="Hudson, Marie" sort="Hudson, Marie" uniqKey="Hudson M" first="Marie" last="Hudson">Marie Hudson</name><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, Department of Internal Medicine, SMBD Jewish General Hospital,</nlm:aff></affiliation><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, Faculty of Medicine, McGill University,</nlm:aff></affiliation></author><author><name sortKey="Tatibouet, Solene" sort="Tatibouet, Solene" uniqKey="Tatibouet S" first="Solène" last="Tatibouet">Solène Tatibouet</name><affiliation><nlm:aff id="ket441-AFF1">Epidemiology, Lady Davis Institute, SMBD Jewish General Hospital,</nlm:aff></affiliation></author><author><name sortKey="Steele, Russell" sort="Steele, Russell" uniqKey="Steele R" first="Russell" last="Steele">Russell Steele</name><affiliation><nlm:aff id="ket441-AFF1">Epidemiology, Lady Davis Institute, SMBD Jewish General Hospital,</nlm:aff></affiliation><affiliation><nlm:aff id="ket441-AFF1">Department of Mathematics and Statistics, McGill University, Montreal, Quebec,</nlm:aff></affiliation></author><author><name sortKey="Lo, Ernest" sort="Lo, Ernest" uniqKey="Lo E" first="Ernest" last="Lo">Ernest Lo</name><affiliation><nlm:aff id="ket441-AFF1">Epidemiology, Lady Davis Institute, SMBD Jewish General Hospital,</nlm:aff></affiliation></author><author><name sortKey="Gravel, Sabrina" sort="Gravel, Sabrina" uniqKey="Gravel S" first="Sabrina" last="Gravel">Sabrina Gravel</name><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, Department of Internal Medicine, SMBD Jewish General Hospital,</nlm:aff></affiliation></author><author><name sortKey="Gyger, Genevieve" sort="Gyger, Genevieve" uniqKey="Gyger G" first="Geneviève" last="Gyger">Geneviève Gyger</name><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, Department of Internal Medicine, SMBD Jewish General Hospital,</nlm:aff></affiliation><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, Faculty of Medicine, McGill University,</nlm:aff></affiliation></author><author><name sortKey="Sayegh, Tarek El" sort="Sayegh, Tarek El" uniqKey="Sayegh T" first="Tarek El" last="Sayegh">Tarek El Sayegh</name><affiliation><nlm:aff id="ket441-AFF1">School of Dentistry, University of Western Ontario,</nlm:aff></affiliation></author><author><name sortKey="Pope, Janet" sort="Pope, Janet" uniqKey="Pope J" first="Janet" last="Pope">Janet Pope</name><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, Department of Medicine, University of Western Ontario, London, Ontario,</nlm:aff></affiliation></author><author><name sortKey="Fontaine, Audrey" sort="Fontaine, Audrey" uniqKey="Fontaine A" first="Audrey" last="Fontaine">Audrey Fontaine</name><affiliation><nlm:aff id="ket441-AFF1">Department of Rheumatology, Université de Sherbrooke, Sherbrooke, Quebec,</nlm:aff></affiliation></author><author><name sortKey="Masseto, Ariel" sort="Masseto, Ariel" uniqKey="Masseto A" first="Ariel" last="Masseto">Ariel Masseto</name><affiliation><nlm:aff id="ket441-AFF1">Department of Rheumatology, Université de Sherbrooke, Sherbrooke, Quebec,</nlm:aff></affiliation></author><author><name sortKey="Matthews, Debora" sort="Matthews, Debora" uniqKey="Matthews D" first="Debora" last="Matthews">Debora Matthews</name><affiliation><nlm:aff id="ket441-AFF1">Department of Periodontology, Faculty of Dentistry,</nlm:aff></affiliation></author><author><name sortKey="Sutton, Evelyn" sort="Sutton, Evelyn" uniqKey="Sutton E" first="Evelyn" last="Sutton">Evelyn Sutton</name><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia,</nlm:aff></affiliation></author><author><name sortKey="Thie, Norman" sort="Thie, Norman" uniqKey="Thie N" first="Norman" last="Thie">Norman Thie</name><affiliation><nlm:aff id="ket441-AFF1">Division of Oro-facial Pain, School of Dentistry,</nlm:aff></affiliation></author><author><name sortKey="Jones, Niall" sort="Jones, Niall" uniqKey="Jones N" first="Niall" last="Jones">Niall Jones</name><affiliation><nlm:aff id="ket441-AFF1">Department of Medicine, University of Alberta, Edmonton, Alberta,</nlm:aff></affiliation></author><author><name sortKey="Copete, Maria" sort="Copete, Maria" uniqKey="Copete M" first="Maria" last="Copete">Maria Copete</name><affiliation><nlm:aff id="ket441-AFF1">Department of Pathology, College of Dentistry, University of Saskatchewan,</nlm:aff></affiliation></author><author><name sortKey="Kolbinson, Dean" sort="Kolbinson, Dean" uniqKey="Kolbinson D" first="Dean" last="Kolbinson">Dean Kolbinson</name><affiliation><nlm:aff id="ket441-AFF1">Department of Pathology, College of Dentistry, University of Saskatchewan,</nlm:aff></affiliation></author><author><name sortKey="Markland, Janet" sort="Markland, Janet" uniqKey="Markland J" first="Janet" last="Markland">Janet Markland</name><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan,</nlm:aff></affiliation></author><author><name sortKey="Nogueira Filho, Getulio" sort="Nogueira Filho, Getulio" uniqKey="Nogueira Filho G" first="Getulio" last="Nogueira-Filho">Getulio Nogueira-Filho</name><affiliation><nlm:aff id="ket441-AFF1">Department of Periodontology,</nlm:aff></affiliation></author><author><name sortKey="Robinson, David" sort="Robinson, David" uniqKey="Robinson D" first="David" last="Robinson">David Robinson</name><affiliation><nlm:aff wicri:cut=" and" id="ket441-AFF1">Rheumatology, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba</nlm:aff></affiliation></author><author><name sortKey="Gornitsky, Mervyn" sort="Gornitsky, Mervyn" uniqKey="Gornitsky M" first="Mervyn" last="Gornitsky">Mervyn Gornitsky</name><affiliation><nlm:aff id="ket441-AFF1">Division of Rheumatology, Faculty of Medicine, McGill University,</nlm:aff></affiliation><affiliation><nlm:aff id="ket441-AFF1">Department of Dentistry, SMBD Jewish General Hospital, Montreal, Quebec, Canada.</nlm:aff></affiliation></author></analytic><series><title level="j">Rheumatology (Oxford, England)</title><idno type="ISSN">1462-0324</idno><idno type="eISSN">1462-0332</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><bold>Objective.</bold> The aim of this study was to compare oral abnormalities and oral health-related quality of life (HRQoL) of patients with SSc with the general population.</p><p><bold>Methods.</bold> SSc patients and healthy controls were enrolled in a multisite cross-sectional study. A standardized oral examination was performed. Oral HRQoL was measured with the Oral Health Impact Profile (OHIP). Multivariate regression analyses were performed to identify associations between SSc, oral abnormalities and oral HRQoL.</p><p><bold>Results.</bold> We assessed 163 SSc patients and 231 controls. SSc patients had more decayed teeth (SSc 0.88, controls 0.59, <italic>P = </italic>0.0465) and periodontal disease [number of teeth with pocket depth (PD) >3 mm or clinical attachment level (CAL) ≥5.5 mm; SSc 5.23, controls 2.94, <italic>P < </italic>0.0001]. SSc patients produced less saliva (SSc 147.52 mg/min, controls 163.19 mg/min, <italic>P = </italic>0.0259) and their interincisal distance was smaller (SSc 37.68 mm, controls 44.30 mm, <italic>P < </italic>0.0001). SSc patients had significantly reduced oral HRQoL compared with controls (mean OHIP score: SSc 41.58, controls 26.67, <italic>P < </italic>0.0001). Multivariate regression analyses confirmed that SSc was a significant independent predictor of missing teeth, periodontal disease, interincisal distance, saliva production and OHIP scores.</p><p><bold>Conclusion.</bold> Subjects with SSc have impaired oral health and oral HRQoL compared with the general population. These data can be used to develop targeted interventions to improve oral health and HRQoL in SSc.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Rheumatology (Oxford)</journal-id><journal-id journal-id-type="iso-abbrev">Rheumatology (Oxford)</journal-id><journal-id journal-id-type="publisher-id">brheum</journal-id><journal-id journal-id-type="hwp">rheumatology</journal-id><journal-title-group><journal-title>Rheumatology (Oxford, England)</journal-title></journal-title-group><issn pub-type="ppub">1462-0324</issn><issn pub-type="epub">1462-0332</issn><publisher><publisher-name>Oxford University Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">24464709</article-id><article-id pub-id-type="pmc">4103515</article-id><article-id pub-id-type="doi">10.1093/rheumatology/ket441</article-id><article-id pub-id-type="publisher-id">ket441</article-id><article-categories><subj-group subj-group-type="heading"><subject>Clinical Science</subject></subj-group></article-categories><title-group><article-title>The Canadian systemic sclerosis oral health study: orofacial manifestations and oral health-related quality of life in systemic sclerosis compared with the general population</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Baron</surname><given-names>Murray</given-names></name><xref ref-type="aff" rid="ket441-AFF1"><sup>1</sup></xref><xref ref-type="aff" rid="ket441-AFF1"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Hudson</surname><given-names>Marie</given-names></name><xref ref-type="aff" rid="ket441-AFF1"><sup>1</sup></xref><xref ref-type="aff" rid="ket441-AFF1"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Tatibouet</surname><given-names>Solène</given-names></name><xref ref-type="aff" rid="ket441-AFF1"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>Steele</surname><given-names>Russell</given-names></name><xref ref-type="aff" rid="ket441-AFF1"><sup>3</sup></xref><xref ref-type="aff" rid="ket441-AFF1"><sup>4</sup></xref></contrib><contrib contrib-type="author"><name><surname>Lo</surname><given-names>Ernest</given-names></name><xref ref-type="aff" rid="ket441-AFF1"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>Gravel</surname><given-names>Sabrina</given-names></name><xref ref-type="aff" rid="ket441-AFF1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Gyger</surname><given-names>Geneviève</given-names></name><xref ref-type="aff" rid="ket441-AFF1"><sup>1</sup></xref><xref ref-type="aff" rid="ket441-AFF1"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Sayegh</surname><given-names>Tarek El</given-names></name><xref ref-type="aff" rid="ket441-AFF1"><sup>5</sup></xref></contrib><contrib contrib-type="author"><name><surname>Pope</surname><given-names>Janet</given-names></name><xref ref-type="aff" rid="ket441-AFF1"><sup>6</sup></xref></contrib><contrib contrib-type="author"><name><surname>Fontaine</surname><given-names>Audrey</given-names></name><xref ref-type="aff" rid="ket441-AFF1"><sup>7</sup></xref></contrib><contrib contrib-type="author"><name><surname>Masseto</surname><given-names>Ariel</given-names></name><xref ref-type="aff" rid="ket441-AFF1"><sup>7</sup></xref></contrib><contrib contrib-type="author"><name><surname>Matthews</surname><given-names>Debora</given-names></name><xref ref-type="aff" rid="ket441-AFF1"><sup>8</sup></xref></contrib><contrib contrib-type="author"><name><surname>Sutton</surname><given-names>Evelyn</given-names></name><xref ref-type="aff" rid="ket441-AFF1"><sup>9</sup></xref></contrib><contrib contrib-type="author"><name><surname>Thie</surname><given-names>Norman</given-names></name><xref ref-type="aff" rid="ket441-AFF1"><sup>10</sup></xref></contrib><contrib contrib-type="author"><name><surname>Jones</surname><given-names>Niall</given-names></name><xref ref-type="aff" rid="ket441-AFF1"><sup>11</sup></xref></contrib><contrib contrib-type="author"><name><surname>Copete</surname><given-names>Maria</given-names></name><xref ref-type="aff" rid="ket441-AFF1"><sup>12</sup></xref></contrib><contrib contrib-type="author"><name><surname>Kolbinson</surname><given-names>Dean</given-names></name><xref ref-type="aff" rid="ket441-AFF1"><sup>12</sup></xref></contrib><contrib contrib-type="author"><name><surname>Markland</surname><given-names>Janet</given-names></name><xref ref-type="aff" rid="ket441-AFF1"><sup>13</sup></xref><xref ref-type="author-notes" rid="ket441-FN1">†</xref></contrib><contrib contrib-type="author"><name><surname>Nogueira-Filho</surname><given-names>Getulio</given-names></name><xref ref-type="aff" rid="ket441-AFF1"><sup>14</sup></xref><xref ref-type="author-notes" rid="ket441-FN2">*</xref></contrib><contrib contrib-type="author"><name><surname>Robinson</surname><given-names>David</given-names></name><xref ref-type="aff" rid="ket441-AFF1"><sup>15</sup></xref></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Gornitsky</surname><given-names>Mervyn</given-names></name><xref ref-type="aff" rid="ket441-AFF1"><sup>2</sup></xref><xref ref-type="aff" rid="ket441-AFF1"><sup>16</sup></xref></contrib><aff id="ket441-AFF1"><sup>1</sup>Division of Rheumatology, Department of Internal Medicine, SMBD Jewish General Hospital,<sup>2</sup>Division of Rheumatology, Faculty of Medicine, McGill University,<sup>3</sup>Epidemiology, Lady Davis Institute, SMBD Jewish General Hospital,<sup>4</sup>Department of Mathematics and Statistics, McGill University, Montreal, Quebec,<sup>5</sup>School of Dentistry, University of Western Ontario,<sup>6</sup>Division of Rheumatology, Department of Medicine, University of Western Ontario, London, Ontario,<sup>7</sup>Department of Rheumatology, Université de Sherbrooke, Sherbrooke, Quebec,<sup>8</sup>Department of Periodontology, Faculty of Dentistry,<sup>9</sup>Division of Rheumatology, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia,<sup>10</sup>Division of Oro-facial Pain, School of Dentistry,<sup>11</sup>Department of Medicine, University of Alberta, Edmonton, Alberta,<sup>12</sup>Department of Pathology, College of Dentistry, University of Saskatchewan,<sup>13</sup>Division of Rheumatology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan,<sup>14</sup>Department of Periodontology,<sup>15</sup>Rheumatology, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba and<sup>16</sup>Department of Dentistry, SMBD Jewish General Hospital, Montreal, Quebec, Canada.</aff></contrib-group><author-notes><corresp>Correspondence to: Mervyn Gornitsky, SMBD Jewish General Hospital, 3755 Cote-Ste-Catherine, A-019, Montreal, QC H3T1E2, Canada. E-mail: <email>mgornits@jgh.mcgill.ca</email></corresp><fn id="ket441-FN1"><p>†Deceased.</p></fn><fn id="ket441-FN2"><p>*Present address: Preventive Dentistry Program, Faculty of Dentistry, University of Toronto, Toronto, ON, Canada.</p></fn></author-notes><pub-date pub-type="ppub"><month>8</month><year>2014</year></pub-date><pub-date pub-type="epub"><day>24</day><month>1</month><year>2014</year></pub-date><pub-date pub-type="pmc-release"><day>1</day><month>8</month><year>2015</year></pub-date><pmc-comment> PMC Release delay is 12 months and 0 days and was based on the
<volume>53</volume><issue>8</issue><fpage>1386</fpage><lpage>1394</lpage><history><date date-type="received"><day>19</day><month>6</month><year>2013</year></date><date date-type="rev-recd"><day>12</day><month>11</month><year>2013</year></date></history><permissions><copyright-statement>© The Author 2014. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com</copyright-statement><copyright-year>2014</copyright-year></permissions><related-article id="d35e342" related-article-type="companion" ext-link-type="doi" xlink:href="10.1093/rheumatology/keu179"></related-article><abstract><p><bold>Objective.</bold> The aim of this study was to compare oral abnormalities and oral health-related quality of life (HRQoL) of patients with SSc with the general population.</p><p><bold>Methods.</bold> SSc patients and healthy controls were enrolled in a multisite cross-sectional study. A standardized oral examination was performed. Oral HRQoL was measured with the Oral Health Impact Profile (OHIP). Multivariate regression analyses were performed to identify associations between SSc, oral abnormalities and oral HRQoL.</p><p><bold>Results.</bold> We assessed 163 SSc patients and 231 controls. SSc patients had more decayed teeth (SSc 0.88, controls 0.59, <italic>P = </italic>0.0465) and periodontal disease [number of teeth with pocket depth (PD) >3 mm or clinical attachment level (CAL) ≥5.5 mm; SSc 5.23, controls 2.94, <italic>P < </italic>0.0001]. SSc patients produced less saliva (SSc 147.52 mg/min, controls 163.19 mg/min, <italic>P = </italic>0.0259) and their interincisal distance was smaller (SSc 37.68 mm, controls 44.30 mm, <italic>P < </italic>0.0001). SSc patients had significantly reduced oral HRQoL compared with controls (mean OHIP score: SSc 41.58, controls 26.67, <italic>P < </italic>0.0001). Multivariate regression analyses confirmed that SSc was a significant independent predictor of missing teeth, periodontal disease, interincisal distance, saliva production and OHIP scores.</p><p><bold>Conclusion.</bold> Subjects with SSc have impaired oral health and oral HRQoL compared with the general population. These data can be used to develop targeted interventions to improve oral health and HRQoL in SSc.</p></abstract><kwd-group><kwd>systemic sclerosis</kwd><kwd>quality of life</kwd><kwd>oral health</kwd><kwd>dental caries</kwd><kwd>periodontal disease</kwd><kwd>Sjögren’s syndrome</kwd><kwd>tooth loss</kwd></kwd-group><counts><page-count count="9"></page-count></counts></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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