An Insight in to Paget's Disease of Bone
Identifieur interne : 000481 ( Pmc/Checkpoint ); précédent : 000480; suivant : 000482An Insight in to Paget's Disease of Bone
Auteurs : Robin Sabharwal ; Shivangi Gupta ; Shipra Sepolia ; Rajat Panigrahi ; Saumyakanta Mohanty ; Santosh Kumar Subudhi ; Manish KumarSource :
- Nigerian Journal of Surgery : Official Publication of the Nigerian Surgical Research Society [ 1117-6806 ] ; 2014.
Abstract
Paget's disease of bone (PDB) is a common disorder which may affect one or many bones. Although many patients are asymptomatic, a variety of symptoms and complications may occur. PDB is a focal disorder of bone turnover characterized by excessive bone resorption coupled with bone formation. PDB begins with a period of increased osteoclastic activity and bone resorption, followed by increased osteoblast production of woven bone that is poorly mineralized. In the final phase of the disease process, dense cortical and trabecular bone deposition predominates, but the bone is sclerotic and poorly organized and lacks the structural integrity and strength of normal bone. This article briefly reviews the etiopathogenesis, clinical radiographic and histological features of Paget's disease.
Url:
DOI: 10.4103/1117-6806.127098
PubMed: 24665195
PubMed Central: 3953635
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
PMC:3953635Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">An Insight in to Paget's Disease of Bone</title><author><name sortKey="Sabharwal, Robin" sort="Sabharwal, Robin" uniqKey="Sabharwal R" first="Robin" last="Sabharwal">Robin Sabharwal</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Gupta, Shivangi" sort="Gupta, Shivangi" uniqKey="Gupta S" first="Shivangi" last="Gupta">Shivangi Gupta</name><affiliation><nlm:aff id="aff2"><italic>Department of Periodontology, DJ College of Dental Sciences and Research, Modinagar, Uttar Pradesh, India</italic></nlm:aff></affiliation></author><author><name sortKey="Sepolia, Shipra" sort="Sepolia, Shipra" uniqKey="Sepolia S" first="Shipra" last="Sepolia">Shipra Sepolia</name><affiliation><nlm:aff id="aff3"><italic>Himachal Dental College and Hospital, Sundernagar, India</italic></nlm:aff></affiliation></author><author><name sortKey="Panigrahi, Rajat" sort="Panigrahi, Rajat" uniqKey="Panigrahi R" first="Rajat" last="Panigrahi">Rajat Panigrahi</name><affiliation><nlm:aff id="aff4"><italic>Department of Oral Medicine and Radiology, Institute of Dental Sciences, Bhubneshwar, India</italic></nlm:aff></affiliation></author><author><name sortKey="Mohanty, Saumyakanta" sort="Mohanty, Saumyakanta" uniqKey="Mohanty S" first="Saumyakanta" last="Mohanty">Saumyakanta Mohanty</name><affiliation><nlm:aff id="aff5"><italic>Department of Conservative Dentistry, Institute of Dental Sciences, Bhubneshwar, India</italic></nlm:aff></affiliation></author><author><name sortKey="Subudhi, Santosh Kumar" sort="Subudhi, Santosh Kumar" uniqKey="Subudhi S" first="Santosh Kumar" last="Subudhi">Santosh Kumar Subudhi</name><affiliation><nlm:aff id="aff6"><italic>Department of Oral and Maxillofacial Surgery, Institute of Dental Sciences, Bhubneshwar, India</italic></nlm:aff></affiliation></author><author><name sortKey="Kumar, Manish" sort="Kumar, Manish" uniqKey="Kumar M" first="Manish" last="Kumar">Manish Kumar</name><affiliation><nlm:aff id="aff7"><italic>Department of Oral Pathology and Microbiology, MMCDSR, Ambala, India</italic></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24665195</idno><idno type="pmc">3953635</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953635</idno><idno type="RBID">PMC:3953635</idno><idno type="doi">10.4103/1117-6806.127098</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">000849</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000849</idno><idno type="wicri:Area/Pmc/Curation">000849</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000849</idno><idno type="wicri:Area/Pmc/Checkpoint">000481</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000481</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">An Insight in to Paget's Disease of Bone</title><author><name sortKey="Sabharwal, Robin" sort="Sabharwal, Robin" uniqKey="Sabharwal R" first="Robin" last="Sabharwal">Robin Sabharwal</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Gupta, Shivangi" sort="Gupta, Shivangi" uniqKey="Gupta S" first="Shivangi" last="Gupta">Shivangi Gupta</name><affiliation><nlm:aff id="aff2"><italic>Department of Periodontology, DJ College of Dental Sciences and Research, Modinagar, Uttar Pradesh, India</italic></nlm:aff></affiliation></author><author><name sortKey="Sepolia, Shipra" sort="Sepolia, Shipra" uniqKey="Sepolia S" first="Shipra" last="Sepolia">Shipra Sepolia</name><affiliation><nlm:aff id="aff3"><italic>Himachal Dental College and Hospital, Sundernagar, India</italic></nlm:aff></affiliation></author><author><name sortKey="Panigrahi, Rajat" sort="Panigrahi, Rajat" uniqKey="Panigrahi R" first="Rajat" last="Panigrahi">Rajat Panigrahi</name><affiliation><nlm:aff id="aff4"><italic>Department of Oral Medicine and Radiology, Institute of Dental Sciences, Bhubneshwar, India</italic></nlm:aff></affiliation></author><author><name sortKey="Mohanty, Saumyakanta" sort="Mohanty, Saumyakanta" uniqKey="Mohanty S" first="Saumyakanta" last="Mohanty">Saumyakanta Mohanty</name><affiliation><nlm:aff id="aff5"><italic>Department of Conservative Dentistry, Institute of Dental Sciences, Bhubneshwar, India</italic></nlm:aff></affiliation></author><author><name sortKey="Subudhi, Santosh Kumar" sort="Subudhi, Santosh Kumar" uniqKey="Subudhi S" first="Santosh Kumar" last="Subudhi">Santosh Kumar Subudhi</name><affiliation><nlm:aff id="aff6"><italic>Department of Oral and Maxillofacial Surgery, Institute of Dental Sciences, Bhubneshwar, India</italic></nlm:aff></affiliation></author><author><name sortKey="Kumar, Manish" sort="Kumar, Manish" uniqKey="Kumar M" first="Manish" last="Kumar">Manish Kumar</name><affiliation><nlm:aff id="aff7"><italic>Department of Oral Pathology and Microbiology, MMCDSR, Ambala, India</italic></nlm:aff></affiliation></author></analytic><series><title level="j">Nigerian Journal of Surgery : Official Publication of the Nigerian Surgical Research Society</title><idno type="ISSN">1117-6806</idno><idno type="eISSN">2278-7100</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Paget's disease of bone (PDB) is a common disorder which may affect one or many bones. Although many patients are asymptomatic, a variety of symptoms and complications may occur. PDB is a focal disorder of bone turnover characterized by excessive bone resorption coupled with bone formation. PDB begins with a period of increased osteoclastic activity and bone resorption, followed by increased osteoblast production of woven bone that is poorly mineralized. In the final phase of the disease process, dense cortical and trabecular bone deposition predominates, but the bone is sclerotic and poorly organized and lacks the structural integrity and strength of normal bone. This article briefly reviews the etiopathogenesis, clinical radiographic and histological features of Paget's disease.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Britton, C" uniqKey="Britton C">C Britton</name></author><author><name sortKey="Walsh, J" uniqKey="Walsh J">J Walsh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shaker, Jl" uniqKey="Shaker J">JL Shaker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rogers, J" uniqKey="Rogers J">J Rogers</name></author><author><name sortKey="Jeffrey, Dr" uniqKey="Jeffrey D">DR Jeffrey</name></author><author><name sortKey="Watt, I" uniqKey="Watt I">I Watt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cooper, C" uniqKey="Cooper C">C Cooper</name></author><author><name sortKey="Harvey, Nc" uniqKey="Harvey N">NC Harvey</name></author><author><name sortKey="Dennison, Em" uniqKey="Dennison E">EM Dennison</name></author><author><name sortKey="Van Staa, Tp" uniqKey="Van Staa T">TP van Staa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Altman, Rd" uniqKey="Altman R">RD Altman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Seton, M" uniqKey="Seton M">M Seton</name></author><author><name sortKey="Choi, Hk" uniqKey="Choi H">HK Choi</name></author><author><name sortKey="Hansen, Mf" uniqKey="Hansen M">MF Hansen</name></author><author><name sortKey="Sebaldt, Rj" uniqKey="Sebaldt R">RJ Sebaldt</name></author><author><name sortKey="Cooper, C" uniqKey="Cooper C">C Cooper</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jilka, Rl" uniqKey="Jilka R">RL Jilka</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Parfitt, Am" uniqKey="Parfitt A">AM Parfitt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Raisz, Lg" uniqKey="Raisz L">LG Raisz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hosking, Dj" uniqKey="Hosking D">DJ Hosking</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rebel, A" uniqKey="Rebel A">A Rebel</name></author><author><name sortKey="Basle, M" uniqKey="Basle M">M Basle</name></author><author><name sortKey="Pouplard, A" uniqKey="Pouplard A">A Pouplard</name></author><author><name sortKey="Malkani, K" uniqKey="Malkani K">K Malkani</name></author><author><name sortKey="Filmon, R" uniqKey="Filmon R">R Filmon</name></author><author><name sortKey="Lepatezour, A" uniqKey="Lepatezour A">A Lepatezour</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Menaa, C" uniqKey="Menaa C">C Menaa</name></author><author><name sortKey="Barsony, J" uniqKey="Barsony J">J Barsony</name></author><author><name sortKey="Reddy, Sv" uniqKey="Reddy S">SV Reddy</name></author><author><name sortKey="Cornish, J" uniqKey="Cornish J">J Cornish</name></author><author><name sortKey="Cundy, T" uniqKey="Cundy T">T Cundy</name></author><author><name sortKey="Roodman, Gd" uniqKey="Roodman G">GD Roodman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Neale, Sd" uniqKey="Neale S">SD Neale</name></author><author><name sortKey="Smith, R" uniqKey="Smith R">R Smith</name></author><author><name sortKey="Wass, Ja" uniqKey="Wass J">JA Wass</name></author><author><name sortKey="Athanasou, Na" uniqKey="Athanasou N">NA Athanasou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Singer, Fr" uniqKey="Singer F">FR Singer</name></author><author><name sortKey="Mills, Bg" uniqKey="Mills B">BG Mills</name></author><author><name sortKey="Gruber, He" uniqKey="Gruber H">HE Gruber</name></author><author><name sortKey="Windle, Jj" uniqKey="Windle J">JJ Windle</name></author><author><name sortKey="Roodman, Gd" uniqKey="Roodman G">GD Roodman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Siris, E" uniqKey="Siris E">E Siris</name></author><author><name sortKey="Roodman, Gd" uniqKey="Roodman G">GD Roodman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Daroszewska, A" uniqKey="Daroszewska A">A Daroszewska</name></author><author><name sortKey="Ralston, Sh" uniqKey="Ralston S">SH Ralston</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mills, Bg" uniqKey="Mills B">BG Mills</name></author><author><name sortKey="Singer, Fr" uniqKey="Singer F">FR Singer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Singer, Fr" uniqKey="Singer F">FR Singer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kurihara, N" uniqKey="Kurihara N">N Kurihara</name></author><author><name sortKey="Reddy, Sv" uniqKey="Reddy S">SV Reddy</name></author><author><name sortKey="Menaa, C" uniqKey="Menaa C">C Menaa</name></author><author><name sortKey="Anderson, D" uniqKey="Anderson D">D Anderson</name></author><author><name sortKey="Roodman, Gd" uniqKey="Roodman G">GD Roodman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Roodman, Gd" uniqKey="Roodman G">GD Roodman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Roodman, Gd" uniqKey="Roodman G">GD Roodman</name></author><author><name sortKey="Windle, Jj" uniqKey="Windle J">JJ Windle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Siris, E" uniqKey="Siris E">E Siris</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thomas, Dw" uniqKey="Thomas D">DW Thomas</name></author><author><name sortKey="Shepherd, Jp" uniqKey="Shepherd J">JP Shepherd</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Navell, Bw" uniqKey="Navell B">BW Navell</name></author><author><name sortKey="Damm, Dd" uniqKey="Damm D">DD Damm</name></author><author><name sortKey="Allen, Cm" uniqKey="Allen C">CM Allen</name></author><author><name sortKey="Bouquot, Je" uniqKey="Bouquot J">JE Bouquot</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Smith, Bj" uniqKey="Smith B">BJ Smith</name></author><author><name sortKey="Eveson, Jw" uniqKey="Eveson J">JW Eveson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ooi, Cg" uniqKey="Ooi C">CG Ooi</name></author><author><name sortKey="Fraser, Wd" uniqKey="Fraser W">WD Fraser</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Russell, Rg" uniqKey="Russell R">RG Russell</name></author><author><name sortKey="Beard, Dj" uniqKey="Beard D">DJ Beard</name></author><author><name sortKey="Cameron, Ec" uniqKey="Cameron E">EC Cameron</name></author><author><name sortKey="Douglas, Dl" uniqKey="Douglas D">DL Douglas</name></author><author><name sortKey="Forrest, Ar" uniqKey="Forrest A">AR Forrest</name></author><author><name sortKey="Guilland Cumming, D" uniqKey="Guilland Cumming D">D Guilland-Cumming</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Licata, Aa" uniqKey="Licata A">AA Licata</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dunford, Je" uniqKey="Dunford J">JE Dunford</name></author><author><name sortKey="Thompson, K" uniqKey="Thompson K">K Thompson</name></author><author><name sortKey="Coxon, Fp" uniqKey="Coxon F">FP Coxon</name></author><author><name sortKey="Luckman, Sp" uniqKey="Luckman S">SP Luckman</name></author><author><name sortKey="Hahn, Fm" uniqKey="Hahn F">FM Hahn</name></author><author><name sortKey="Poulter, Cd" uniqKey="Poulter C">CD Poulter</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ralston, Sh" uniqKey="Ralston S">SH Ralston</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Seton, M" uniqKey="Seton M">M Seton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Langston, Al" uniqKey="Langston A">AL Langston</name></author><author><name sortKey="Campbell, Mk" uniqKey="Campbell M">MK Campbell</name></author><author><name sortKey="Fraser, Wd" uniqKey="Fraser W">WD Fraser</name></author><author><name sortKey="Maclennan, Gs" uniqKey="Maclennan G">GS MacLennan</name></author><author><name sortKey="Selby, Pl" uniqKey="Selby P">PL Selby</name></author><author><name sortKey="Ralston, Sh" uniqKey="Ralston S">SH Ralston</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Reid, Ir" uniqKey="Reid I">IR Reid</name></author><author><name sortKey="Lyles, K" uniqKey="Lyles K">K Lyles</name></author><author><name sortKey="Su, G" uniqKey="Su G">G Su</name></author><author><name sortKey="Brown, Jp" uniqKey="Brown J">JP Brown</name></author><author><name sortKey="Walsh, Jp" uniqKey="Walsh J">JP Walsh</name></author><author><name sortKey="Del Pino Montes, J" uniqKey="Del Pino Montes J">J del Pino-Montes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hirao, M" uniqKey="Hirao M">M Hirao</name></author><author><name sortKey="Hashimoto, J" uniqKey="Hashimoto J">J Hashimoto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Parvizi, J" uniqKey="Parvizi J">J Parvizi</name></author><author><name sortKey="Klein, Gr" uniqKey="Klein G">GR Klein</name></author><author><name sortKey="Sim, Fh" uniqKey="Sim F">FH Sim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rongstad, Km" uniqKey="Rongstad K">KM Rongstad</name></author><author><name sortKey="Wheeler, Dl" uniqKey="Wheeler D">DL Wheeler</name></author><author><name sortKey="Enneking, Wf" uniqKey="Enneking W">WF Enneking</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="review-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Niger J Surg</journal-id><journal-id journal-id-type="iso-abbrev">Niger J Surg</journal-id><journal-id journal-id-type="publisher-id">NJS</journal-id><journal-title-group><journal-title>Nigerian Journal of Surgery : Official Publication of the Nigerian Surgical Research Society</journal-title></journal-title-group><issn pub-type="ppub">1117-6806</issn><issn pub-type="epub">2278-7100</issn><publisher><publisher-name>Medknow Publications & Media Pvt Ltd</publisher-name><publisher-loc>India</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">24665195</article-id><article-id pub-id-type="pmc">3953635</article-id><article-id pub-id-type="publisher-id">NJS-20-9</article-id><article-id pub-id-type="doi">10.4103/1117-6806.127098</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title>An Insight in to Paget's Disease of Bone</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Sabharwal</surname><given-names>Robin</given-names></name><xref ref-type="aff" rid="aff1"></xref><xref ref-type="corresp" rid="cor1"></xref></contrib><contrib contrib-type="author"><name><surname>Gupta</surname><given-names>Shivangi</given-names></name><xref ref-type="aff" rid="aff2">1</xref></contrib><contrib contrib-type="author"><name><surname>Sepolia</surname><given-names>Shipra</given-names></name><xref ref-type="aff" rid="aff3">2</xref></contrib><contrib contrib-type="author"><name><surname>Panigrahi</surname><given-names>Rajat</given-names></name><xref ref-type="aff" rid="aff4">3</xref></contrib><contrib contrib-type="author"><name><surname>Mohanty</surname><given-names>Saumyakanta</given-names></name><xref ref-type="aff" rid="aff5">4</xref></contrib><contrib contrib-type="author"><name><surname>Subudhi</surname><given-names>Santosh Kumar</given-names></name><xref ref-type="aff" rid="aff6">5</xref></contrib><contrib contrib-type="author"><name><surname>Kumar</surname><given-names>Manish</given-names></name><xref ref-type="aff" rid="aff7">6</xref></contrib></contrib-group><aff id="aff1"><italic>Department of Oral Pathology and Microbiology, Bhojia Dental College and Hospital, Baddi, India</italic></aff><aff id="aff2"><label>1</label><italic>Department of Periodontology, DJ College of Dental Sciences and Research, Modinagar, Uttar Pradesh, India</italic></aff><aff id="aff3"><label>2</label><italic>Himachal Dental College and Hospital, Sundernagar, India</italic></aff><aff id="aff4"><label>3</label><italic>Department of Oral Medicine and Radiology, Institute of Dental Sciences, Bhubneshwar, India</italic></aff><aff id="aff5"><label>4</label><italic>Department of Conservative Dentistry, Institute of Dental Sciences, Bhubneshwar, India</italic></aff><aff id="aff6"><label>5</label><italic>Department of Oral and Maxillofacial Surgery, Institute of Dental Sciences, Bhubneshwar, India</italic></aff><aff id="aff7"><label>6</label><italic>Department of Oral Pathology and Microbiology, MMCDSR, Ambala, India</italic></aff><author-notes><corresp id="cor1"><bold>Address for correspondence:</bold> Dr. Robin Sabharwal, Department of Oral Pathology and Microbiology, Bhojia Dental College and Hospital, Baddi, India. E-mail: <email xlink:href="robin.sabharwal@yahoo.co.in">robin.sabharwal@yahoo.co.in</email></corresp></author-notes><pub-date pub-type="ppub"><season>Jan-Jun</season><year>2014</year></pub-date><volume>20</volume><issue>1</issue><fpage>9</fpage><lpage>15</lpage><permissions><copyright-statement>Copyright: © Nigerian Journal of Surgery</copyright-statement><copyright-year>2014</copyright-year><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-sa/3.0"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><abstract><p>Paget's disease of bone (PDB) is a common disorder which may affect one or many bones. Although many patients are asymptomatic, a variety of symptoms and complications may occur. PDB is a focal disorder of bone turnover characterized by excessive bone resorption coupled with bone formation. PDB begins with a period of increased osteoclastic activity and bone resorption, followed by increased osteoblast production of woven bone that is poorly mineralized. In the final phase of the disease process, dense cortical and trabecular bone deposition predominates, but the bone is sclerotic and poorly organized and lacks the structural integrity and strength of normal bone. This article briefly reviews the etiopathogenesis, clinical radiographic and histological features of Paget's disease.</p></abstract><kwd-group><title>K<sc>EYWORDS</sc></title><kwd>Osteoclast</kwd><kwd>osteoprotegerin</kwd><kwd>receptor activator of NF-κB</kwd><kwd>receptor activator of NF-κB ligand</kwd></kwd-group></article-meta></front></pmc><affiliations><list></list><tree><noCountry><name sortKey="Gupta, Shivangi" sort="Gupta, Shivangi" uniqKey="Gupta S" first="Shivangi" last="Gupta">Shivangi Gupta</name><name sortKey="Kumar, Manish" sort="Kumar, Manish" uniqKey="Kumar M" first="Manish" last="Kumar">Manish Kumar</name><name sortKey="Mohanty, Saumyakanta" sort="Mohanty, Saumyakanta" uniqKey="Mohanty S" first="Saumyakanta" last="Mohanty">Saumyakanta Mohanty</name><name sortKey="Panigrahi, Rajat" sort="Panigrahi, Rajat" uniqKey="Panigrahi R" first="Rajat" last="Panigrahi">Rajat Panigrahi</name><name sortKey="Sabharwal, Robin" sort="Sabharwal, Robin" uniqKey="Sabharwal R" first="Robin" last="Sabharwal">Robin Sabharwal</name><name sortKey="Sepolia, Shipra" sort="Sepolia, Shipra" uniqKey="Sepolia S" first="Shipra" last="Sepolia">Shipra Sepolia</name><name sortKey="Subudhi, Santosh Kumar" sort="Subudhi, Santosh Kumar" uniqKey="Subudhi S" first="Santosh Kumar" last="Subudhi">Santosh Kumar Subudhi</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV1/Data/Pmc/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000481 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd -nk 000481 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= EdenteV1
|flux= Pmc
|étape= Checkpoint
|type= RBID
|clé= PMC:3953635
|texte= An Insight in to Paget's Disease of Bone
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/RBID.i -Sk "pubmed:24665195" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a EdenteV1
| This area was generated with Dilib version V0.6.33. |  |