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Combined therapy in a patient with Papillon-Lefèvre syndrome : A 13-year follow-up

Identifieur interne : 000291 ( PascalFrancis/Curation ); précédent : 000290; suivant : 000292

Combined therapy in a patient with Papillon-Lefèvre syndrome : A 13-year follow-up

Auteurs : Hilal Islu Toygar [Turquie] ; Cem Kircelli [Turquie] ; Ezgi Firat ; Esra Guzeldemir [Turquie]

Source :

RBID : Pascal:07-0448721

Descripteurs français

English descriptors

Abstract

Background: Papillon-Lefèvre syndrome (PLS) is an autosomal recessive disease characterized by hyperkeratosis of the palms and soles combined with premature loss of the primary and permanent dentition. Several treatment regimens have been recommended in the literature; however, a definitive treatment protocol has not been established. This case report evaluates the success of combined therapy in managing a patient with PLS. Methods: A 6-year-old girl diagnosed with PLS presented with aggressive periodontal destruction of her primary and permanent dentitions. After extraction of periodontally affected teeth, the edentate region was rehabilitated with different temporary dentures until her skeletal growth was complete. At the same time, her orthodontic treatment was performed. The early loss of her incisors resulted in inadequate alveolar bone height and width for esthetic-advanced prosthetic rehabilitation. Alveolar bone augmentation was performed, and 6 months later, two intraosseous dental implants were placed into the central incisor zone. Results: After 13 years of treatment and follow-up, the patient had periodontally healthy permanent dentition. She had practiced meticulous oral hygiene, and the orthodontic treatment was successful and without incident. Alveolar ridge augmentation and placement of an intraosseous implant with guided bone regeneration were performed successfully. Conclusions: This case report demonstrates that individually developed treatment protocols can provide long-term dental/periodontal success in patients with PLS. A multidisciplinary approach with advanced periodontal surgery, orthodontic and prosthetic treatment, and implant therapy may be an appropriate treatment modality for dental rehabilitation in patients with PLS.
pA  
A01 01  1    @0 0022-3492
A03   1    @0 J. periodontol.
A05       @2 78
A06       @2 9
A08 01  1  ENG  @1 Combined therapy in a patient with Papillon-Lefèvre syndrome : A 13-year follow-up
A11 01  1    @1 TOYGAR (Hilal Islu)
A11 02  1    @1 KIRCELLI (Cem)
A11 03  1    @1 FIRAT (Ezgi)
A11 04  1    @1 GUZELDEMIR (Esra)
A14 01      @1 Department of Periodontology, Faculty of Dentistry, Baskent University @2 Ankara @3 TUR @Z 1 aut. @Z 4 aut.
A14 02      @1 Department of Prosthodontics, Faculty of Dentistry, Baskent University @3 TUR @Z 2 aut.
A20       @1 1819-1824
A21       @1 2007
A23 01      @0 ENG
A43 01      @1 INIST @2 874 @5 354000162506650230
A44       @0 0000 @1 © 2007 INIST-CNRS. All rights reserved.
A45       @0 28 ref.
A47 01  1    @0 07-0448721
A60       @1 P @3 EC
A61       @0 A
A64 01  1    @0 Journal of periodontology
A66 01      @0 USA
C01 01    ENG  @0 Background: Papillon-Lefèvre syndrome (PLS) is an autosomal recessive disease characterized by hyperkeratosis of the palms and soles combined with premature loss of the primary and permanent dentition. Several treatment regimens have been recommended in the literature; however, a definitive treatment protocol has not been established. This case report evaluates the success of combined therapy in managing a patient with PLS. Methods: A 6-year-old girl diagnosed with PLS presented with aggressive periodontal destruction of her primary and permanent dentitions. After extraction of periodontally affected teeth, the edentate region was rehabilitated with different temporary dentures until her skeletal growth was complete. At the same time, her orthodontic treatment was performed. The early loss of her incisors resulted in inadequate alveolar bone height and width for esthetic-advanced prosthetic rehabilitation. Alveolar bone augmentation was performed, and 6 months later, two intraosseous dental implants were placed into the central incisor zone. Results: After 13 years of treatment and follow-up, the patient had periodontally healthy permanent dentition. She had practiced meticulous oral hygiene, and the orthodontic treatment was successful and without incident. Alveolar ridge augmentation and placement of an intraosseous implant with guided bone regeneration were performed successfully. Conclusions: This case report demonstrates that individually developed treatment protocols can provide long-term dental/periodontal success in patients with PLS. A multidisciplinary approach with advanced periodontal surgery, orthodontic and prosthetic treatment, and implant therapy may be an appropriate treatment modality for dental rehabilitation in patients with PLS.
C02 01  X    @0 002B08I
C03 01  X  FRE  @0 Kératodermie palmoplantaire Papillon Lefèvre @5 01
C03 01  X  ENG  @0 Keratoderma palmoplantaris Papillon Lefevre @5 01
C03 01  X  SPA  @0 Queratodermia palmoplantar Papillón Lefevre @5 01
C03 02  X  FRE  @0 Orthodontie @5 04
C03 02  X  ENG  @0 Orthodontic procedures @5 04
C03 02  X  SPA  @0 Ortodoncia @5 04
C03 03  X  FRE  @0 Traitement associé @5 07
C03 03  X  ENG  @0 Combined treatment @5 07
C03 03  X  SPA  @0 Tratamiento asociado @5 07
C03 04  X  FRE  @0 Homme @5 08
C03 04  X  ENG  @0 Human @5 08
C03 04  X  SPA  @0 Hombre @5 08
C03 05  X  FRE  @0 Etude longitudinale @5 09
C03 05  X  ENG  @0 Follow up study @5 09
C03 05  X  SPA  @0 Estudio longitudinal @5 09
C03 06  X  FRE  @0 Dent @5 13
C03 06  X  ENG  @0 Tooth @5 13
C03 06  X  SPA  @0 Diente @5 13
C03 07  X  FRE  @0 Implant @5 14
C03 07  X  ENG  @0 Implant @5 14
C03 07  X  SPA  @0 Implante @5 14
C03 08  X  FRE  @0 Régénération @5 15
C03 08  X  ENG  @0 Regeneration @5 15
C03 08  X  SPA  @0 Regeneración @5 15
C03 09  X  FRE  @0 Dentisterie @5 16
C03 09  X  ENG  @0 Dentistry @5 16
C03 09  X  SPA  @0 Odontología @5 16
C07 01  X  FRE  @0 Dyskératose @5 37
C07 01  X  ENG  @0 Dyskeratosis @5 37
C07 01  X  SPA  @0 Disqueratosis @5 37
C07 02  X  FRE  @0 Hyperkératose @5 38
C07 02  X  ENG  @0 Hyperkeratosis @5 38
C07 02  X  SPA  @0 Hiperqueratosis @5 38
C07 03  X  FRE  @0 Maladie héréditaire @5 39
C07 03  X  ENG  @0 Genetic disease @5 39
C07 03  X  SPA  @0 Enfermedad hereditaria @5 39
C07 04  X  FRE  @0 Peau pathologie @5 40
C07 04  X  ENG  @0 Skin disease @5 40
C07 04  X  SPA  @0 Piel patología @5 40
N21       @1 295
N44 01      @1 OTO
N82       @1 OTO

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<div type="abstract" xml:lang="en">Background: Papillon-Lefèvre syndrome (PLS) is an autosomal recessive disease characterized by hyperkeratosis of the palms and soles combined with premature loss of the primary and permanent dentition. Several treatment regimens have been recommended in the literature; however, a definitive treatment protocol has not been established. This case report evaluates the success of combined therapy in managing a patient with PLS. Methods: A 6-year-old girl diagnosed with PLS presented with aggressive periodontal destruction of her primary and permanent dentitions. After extraction of periodontally affected teeth, the edentate region was rehabilitated with different temporary dentures until her skeletal growth was complete. At the same time, her orthodontic treatment was performed. The early loss of her incisors resulted in inadequate alveolar bone height and width for esthetic-advanced prosthetic rehabilitation. Alveolar bone augmentation was performed, and 6 months later, two intraosseous dental implants were placed into the central incisor zone. Results: After 13 years of treatment and follow-up, the patient had periodontally healthy permanent dentition. She had practiced meticulous oral hygiene, and the orthodontic treatment was successful and without incident. Alveolar ridge augmentation and placement of an intraosseous implant with guided bone regeneration were performed successfully. Conclusions: This case report demonstrates that individually developed treatment protocols can provide long-term dental/periodontal success in patients with PLS. A multidisciplinary approach with advanced periodontal surgery, orthodontic and prosthetic treatment, and implant therapy may be an appropriate treatment modality for dental rehabilitation in patients with PLS.</div>
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