EdenteV1, PascalFrancis, Corpus, bibRecord, 000277

Effect of platelet-rich plasma on sinus lifting: a randomized- controlled clinical trial

Identifieur interne : 000277 ( PascalFrancis/Corpus ); précédent : 000276; suivant : 000278

Effect of platelet-rich plasma on sinus lifting: a randomized- controlled clinical trial

Auteurs : Jesús Torres ; Faleh Tamimi ; Pedro-Pablo Martinez ; MOHAMMAD HAMDAN ALKHRAISAT ; Rafael Linares ; Gonzalo Hernandez ; Juan Torres-Macho ; Enrique Lopez-Cabarcos

Source :

Journal of clinical periodontology [ 0303-6979 ] ; 2009.

RBID : Pascal:09-0314268

Descripteurs français

Pascal (Inist)
- Thrombocyte, Plasma sanguin, Rhytidoplastie, Essai clinique, Bovin, Os, Régénération, Plancher, Dentisterie.

English descriptors

KwdEn :
- Blood plasma, Bone, Bovine, Clinical trial, Dentistry, Floor, Lifting, Platelet, Regeneration.

Abstract

Objective: The combination of anorganic bovine bone (ABB) with platelet-rich plasma (PRP) has been widely used in bone regeneration procedures although its benefits are still unclear. The purpose of this study was to evaluate whether or not PRP improves the efficacy of ABB in sinus floor augmentation. In addition, we have investigated the effect of residual bone height and tobacco on implant survival in sinus augmentation procedures. Patient and Methods: Eighty-seven patients recruited for this study underwent 144 sinus floor augmentation procedures using ABB alone or ABB plus PRP (ABB + PRP) in a randomized clinical trial. A total of 286 implants were placed in the augmented bone, and their evolution was followed up for a period of 24 months. In order to investigate on a histological level and any adjunctive effects, we performed an ancillary study in five edentulous patients with a symmetrical severely resorbed maxilla. In these patients, a bilateral sinus augmentation was randomly performed using ABB or ABB + PRP in a split-mouth design, and after 6 months, bone biopsies were taken from the implant sites for histological and histomorphometric analysis. Results: Overall, 96.2% of ABB and 98.6% of ABB+PRP implant success were obtained during the monitoring period and differences were not found between sites grafted with and without PRP in the 87 patients studied. Densitometry assessments and graft resorption were similar in both experimental groups. However, the histological and histomorphometrical analysis in the five edentulous patients revealed that bone augmentation was significantly higher in sites treated with ABB+PRP (p ≤ 0.05). Another outcome from our study is that the lack of initial bone support (p ≤ 0.05) and smoking (p = 0.05) appeared to have a negative effect on the treatment success, which was accentuated when both circumstances coincided. Conclusions: PRP is not a determining factor for implant survival in sinus lifting procedures. However, this study revealed that PRP can improve the osteoconductive properties of ABB by increasing the volume of new bone formed. Moreover, in sinus augmentation procedures the implant's survival rate appears to be more influenced by the residual bone height or by tobacco than by the type of bone graft.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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C01	`01`		`ENG`	@0 Objective: The combination of anorganic bovine bone (ABB) with platelet-rich plasma (PRP) has been widely used in bone regeneration procedures although its benefits are still unclear. The purpose of this study was to evaluate whether or not PRP improves the efficacy of ABB in sinus floor augmentation. In addition, we have investigated the effect of residual bone height and tobacco on implant survival in sinus augmentation procedures. Patient and Methods: Eighty-seven patients recruited for this study underwent 144 sinus floor augmentation procedures using ABB alone or ABB plus PRP (ABB + PRP) in a randomized clinical trial. A total of 286 implants were placed in the augmented bone, and their evolution was followed up for a period of 24 months. In order to investigate on a histological level and any adjunctive effects, we performed an ancillary study in five edentulous patients with a symmetrical severely resorbed maxilla. In these patients, a bilateral sinus augmentation was randomly performed using ABB or ABB + PRP in a split-mouth design, and after 6 months, bone biopsies were taken from the implant sites for histological and histomorphometric analysis. Results: Overall, 96.2% of ABB and 98.6% of ABB+PRP implant success were obtained during the monitoring period and differences were not found between sites grafted with and without PRP in the 87 patients studied. Densitometry assessments and graft resorption were similar in both experimental groups. However, the histological and histomorphometrical analysis in the five edentulous patients revealed that bone augmentation was significantly higher in sites treated with ABB+PRP (p ≤ 0.05). Another outcome from our study is that the lack of initial bone support (p ≤ 0.05) and smoking (p = 0.05) appeared to have a negative effect on the treatment success, which was accentuated when both circumstances coincided. Conclusions: PRP is not a determining factor for implant survival in sinus lifting procedures. However, this study revealed that PRP can improve the osteoconductive properties of ABB by increasing the volume of new bone formed. Moreover, in sinus augmentation procedures the implant's survival rate appears to be more influenced by the residual bone height or by tobacco than by the type of bone graft.
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Format Inist (serveur)

NO :	PASCAL 09-0314268 INIST
ET :	Effect of platelet-rich plasma on sinus lifting: a randomized- controlled clinical trial
AU :	TORRES (Jesús); TAMIMI (Faleh); MARTINEZ (Pedro-Pablo); MOHAMMAD HAMDAN ALKHRAISAT; LINARES (Rafael); HERNANDEZ (Gonzalo); TORRES-MACHO (Juan); LOPEZ-CABARCOS (Enrique)
AF :	Ciencias de la Salud III, Universidad Rey Juan Carlos/Alcorcón/Espagne (1 aut., 5 aut.); Private practice, Clinica Dental Alcalá/Madrid/Espagne (1 aut., 2 aut., 3 aut.); Faculty of Dentistry, McGill University/Montreal, QC/Canada (2 aut.); Faculty of Pharmacy, Universidad Complutense/Madrid/Espagne (4 aut., 8 aut.); Faculty of Dentistry, Universidad Complutense/Madrid/Espagne (6 aut.); Hospital Infanta Cristina, Parla/Madrid/Espagne (7 aut.)
DT :	Publication en série; Niveau analytique
SO :	Journal of clinical periodontology; ISSN 0303-6979; Royaume-Uni; Da. 2009; Vol. 36; No. 8; Pp. 677-687; Bibl. 2 p.1/4
LA :	Anglais
EA :	Objective: The combination of anorganic bovine bone (ABB) with platelet-rich plasma (PRP) has been widely used in bone regeneration procedures although its benefits are still unclear. The purpose of this study was to evaluate whether or not PRP improves the efficacy of ABB in sinus floor augmentation. In addition, we have investigated the effect of residual bone height and tobacco on implant survival in sinus augmentation procedures. Patient and Methods: Eighty-seven patients recruited for this study underwent 144 sinus floor augmentation procedures using ABB alone or ABB plus PRP (ABB + PRP) in a randomized clinical trial. A total of 286 implants were placed in the augmented bone, and their evolution was followed up for a period of 24 months. In order to investigate on a histological level and any adjunctive effects, we performed an ancillary study in five edentulous patients with a symmetrical severely resorbed maxilla. In these patients, a bilateral sinus augmentation was randomly performed using ABB or ABB + PRP in a split-mouth design, and after 6 months, bone biopsies were taken from the implant sites for histological and histomorphometric analysis. Results: Overall, 96.2% of ABB and 98.6% of ABB+PRP implant success were obtained during the monitoring period and differences were not found between sites grafted with and without PRP in the 87 patients studied. Densitometry assessments and graft resorption were similar in both experimental groups. However, the histological and histomorphometrical analysis in the five edentulous patients revealed that bone augmentation was significantly higher in sites treated with ABB+PRP (p ≤ 0.05). Another outcome from our study is that the lack of initial bone support (p ≤ 0.05) and smoking (p = 0.05) appeared to have a negative effect on the treatment success, which was accentuated when both circumstances coincided. Conclusions: PRP is not a determining factor for implant survival in sinus lifting procedures. However, this study revealed that PRP can improve the osteoconductive properties of ABB by increasing the volume of new bone formed. Moreover, in sinus augmentation procedures the implant's survival rate appears to be more influenced by the residual bone height or by tobacco than by the type of bone graft.
CC :	002B10C02
FD :	Thrombocyte; Plasma sanguin; Rhytidoplastie; Essai clinique; Bovin; Os; Régénération; Plancher; Dentisterie
FG :	Artiodactyla; Ungulata; Mammalia; Vertebrata
ED :	Platelet; Blood plasma; Lifting; Clinical trial; Bovine; Bone; Regeneration; Floor; Dentistry
EG :	Artiodactyla; Ungulata; Mammalia; Vertebrata
SD :	Trombocito; Plasma sanguíneo; Ritidoplastia; Ensayo clínico; Bovino; Hueso; Regeneración; Piso; Odontología
LO :	INIST-16273.354000187226790090
ID :	09-0314268

Links to Exploration step

Pascal:09-0314268

Le document en format XML

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<front><div type="abstract" xml:lang="en">Objective: The combination of anorganic bovine bone (ABB) with platelet-rich plasma (PRP) has been widely used in bone regeneration procedures although its benefits are still unclear. The purpose of this study was to evaluate whether or not PRP improves the efficacy of ABB in sinus floor augmentation. In addition, we have investigated the effect of residual bone height and tobacco on implant survival in sinus augmentation procedures. Patient and Methods: Eighty-seven patients recruited for this study underwent 144 sinus floor augmentation procedures using ABB alone or ABB plus PRP (ABB + PRP) in a randomized clinical trial. A total of 286 implants were placed in the augmented bone, and their evolution was followed up for a period of 24 months. In order to investigate on a histological level and any adjunctive effects, we performed an ancillary study in five edentulous patients with a symmetrical severely resorbed maxilla. In these patients, a bilateral sinus augmentation was randomly performed using ABB or ABB + PRP in a split-mouth design, and after 6 months, bone biopsies were taken from the implant sites for histological and histomorphometric analysis. Results: Overall, 96.2% of ABB and 98.6% of ABB+PRP implant success were obtained during the monitoring period and differences were not found between sites grafted with and without PRP in the 87 patients studied. Densitometry assessments and graft resorption were similar in both experimental groups. However, the histological and histomorphometrical analysis in the five edentulous patients revealed that bone augmentation was significantly higher in sites treated with ABB+PRP (p ≤ 0.05). Another outcome from our study is that the lack of initial bone support (p ≤ 0.05) and smoking (p = 0.05) appeared to have a negative effect on the treatment success, which was accentuated when both circumstances coincided. Conclusions: PRP is not a determining factor for implant survival in sinus lifting procedures. However, this study revealed that PRP can improve the osteoconductive properties of ABB by increasing the volume of new bone formed. Moreover, in sinus augmentation procedures the implant's survival rate appears to be more influenced by the residual bone height or by tobacco than by the type of bone graft.</div>
</front>
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<inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0303-6979</s0>
</fA01>
<fA03 i2="1"><s0>J. clin. periodontol.</s0>
</fA03>
<fA05><s2>36</s2>
</fA05>
<fA06><s2>8</s2>
</fA06>
<fA08 i1="01" i2="1" l="ENG"><s1>Effect of platelet-rich plasma on sinus lifting: a randomized- controlled clinical trial</s1>
</fA08>
<fA11 i1="01" i2="1"><s1>TORRES (Jesús)</s1>
</fA11>
<fA11 i1="02" i2="1"><s1>TAMIMI (Faleh)</s1>
</fA11>
<fA11 i1="03" i2="1"><s1>MARTINEZ (Pedro-Pablo)</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>MOHAMMAD HAMDAN ALKHRAISAT</s1>
</fA11>
<fA11 i1="05" i2="1"><s1>LINARES (Rafael)</s1>
</fA11>
<fA11 i1="06" i2="1"><s1>HERNANDEZ (Gonzalo)</s1>
</fA11>
<fA11 i1="07" i2="1"><s1>TORRES-MACHO (Juan)</s1>
</fA11>
<fA11 i1="08" i2="1"><s1>LOPEZ-CABARCOS (Enrique)</s1>
</fA11>
<fA14 i1="01"><s1>Ciencias de la Salud III, Universidad Rey Juan Carlos</s1>
<s2>Alcorcón</s2>
<s3>ESP</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>Private practice, Clinica Dental Alcalá</s1>
<s2>Madrid</s2>
<s3>ESP</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>Faculty of Dentistry, McGill University</s1>
<s2>Montreal, QC</s2>
<s3>CAN</s3>
<sZ>2 aut.</sZ>
</fA14>
<fA14 i1="04"><s1>Faculty of Pharmacy, Universidad Complutense</s1>
<s2>Madrid</s2>
<s3>ESP</s3>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
</fA14>
<fA14 i1="05"><s1>Faculty of Dentistry, Universidad Complutense</s1>
<s2>Madrid</s2>
<s3>ESP</s3>
<sZ>6 aut.</sZ>
</fA14>
<fA14 i1="06"><s1>Hospital Infanta Cristina, Parla</s1>
<s2>Madrid</s2>
<s3>ESP</s3>
<sZ>7 aut.</sZ>
</fA14>
<fA20><s1>677-687</s1>
</fA20>
<fA21><s1>2009</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
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<s5>354000187226790090</s5>
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<fA61><s0>A</s0>
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<fA64 i1="01" i2="1"><s0>Journal of clinical periodontology</s0>
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<fA66 i1="01"><s0>GBR</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>Objective: The combination of anorganic bovine bone (ABB) with platelet-rich plasma (PRP) has been widely used in bone regeneration procedures although its benefits are still unclear. The purpose of this study was to evaluate whether or not PRP improves the efficacy of ABB in sinus floor augmentation. In addition, we have investigated the effect of residual bone height and tobacco on implant survival in sinus augmentation procedures. Patient and Methods: Eighty-seven patients recruited for this study underwent 144 sinus floor augmentation procedures using ABB alone or ABB plus PRP (ABB + PRP) in a randomized clinical trial. A total of 286 implants were placed in the augmented bone, and their evolution was followed up for a period of 24 months. In order to investigate on a histological level and any adjunctive effects, we performed an ancillary study in five edentulous patients with a symmetrical severely resorbed maxilla. In these patients, a bilateral sinus augmentation was randomly performed using ABB or ABB + PRP in a split-mouth design, and after 6 months, bone biopsies were taken from the implant sites for histological and histomorphometric analysis. Results: Overall, 96.2% of ABB and 98.6% of ABB+PRP implant success were obtained during the monitoring period and differences were not found between sites grafted with and without PRP in the 87 patients studied. Densitometry assessments and graft resorption were similar in both experimental groups. However, the histological and histomorphometrical analysis in the five edentulous patients revealed that bone augmentation was significantly higher in sites treated with ABB+PRP (p ≤ 0.05). Another outcome from our study is that the lack of initial bone support (p ≤ 0.05) and smoking (p = 0.05) appeared to have a negative effect on the treatment success, which was accentuated when both circumstances coincided. Conclusions: PRP is not a determining factor for implant survival in sinus lifting procedures. However, this study revealed that PRP can improve the osteoconductive properties of ABB by increasing the volume of new bone formed. Moreover, in sinus augmentation procedures the implant's survival rate appears to be more influenced by the residual bone height or by tobacco than by the type of bone graft.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B10C02</s0>
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<s5>07</s5>
</fC03>
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<s5>07</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Trombocito</s0>
<s5>07</s5>
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<s5>08</s5>
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<s5>08</s5>
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<s5>08</s5>
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<fC03 i1="03" i2="X" l="FRE"><s0>Rhytidoplastie</s0>
<s5>09</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Lifting</s0>
<s5>09</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Ritidoplastia</s0>
<s5>09</s5>
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<s5>13</s5>
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<s5>14</s5>
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<s5>15</s5>
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<s5>15</s5>
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<s5>16</s5>
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<s5>17</s5>
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<s5>30</s5>
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<s5>30</s5>
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<s5>30</s5>
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<s2>NS</s2>
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<s2>NS</s2>
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<fC07 i1="01" i2="X" l="SPA"><s0>Artiodactyla</s0>
<s2>NS</s2>
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<s2>NS</s2>
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<s2>NS</s2>
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<s2>NS</s2>
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<server><NO>PASCAL 09-0314268 INIST</NO>
<ET>Effect of platelet-rich plasma on sinus lifting: a randomized- controlled clinical trial</ET>
<AU>TORRES (Jesús); TAMIMI (Faleh); MARTINEZ (Pedro-Pablo); MOHAMMAD HAMDAN ALKHRAISAT; LINARES (Rafael); HERNANDEZ (Gonzalo); TORRES-MACHO (Juan); LOPEZ-CABARCOS (Enrique)</AU>
<AF>Ciencias de la Salud III, Universidad Rey Juan Carlos/Alcorcón/Espagne (1 aut., 5 aut.); Private practice, Clinica Dental Alcalá/Madrid/Espagne (1 aut., 2 aut., 3 aut.); Faculty of Dentistry, McGill University/Montreal, QC/Canada (2 aut.); Faculty of Pharmacy, Universidad Complutense/Madrid/Espagne (4 aut., 8 aut.); Faculty of Dentistry, Universidad Complutense/Madrid/Espagne (6 aut.); Hospital Infanta Cristina, Parla/Madrid/Espagne (7 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Journal of clinical periodontology; ISSN 0303-6979; Royaume-Uni; Da. 2009; Vol. 36; No. 8; Pp. 677-687; Bibl. 2 p.1/4</SO>
<LA>Anglais</LA>
<EA>Objective: The combination of anorganic bovine bone (ABB) with platelet-rich plasma (PRP) has been widely used in bone regeneration procedures although its benefits are still unclear. The purpose of this study was to evaluate whether or not PRP improves the efficacy of ABB in sinus floor augmentation. In addition, we have investigated the effect of residual bone height and tobacco on implant survival in sinus augmentation procedures. Patient and Methods: Eighty-seven patients recruited for this study underwent 144 sinus floor augmentation procedures using ABB alone or ABB plus PRP (ABB + PRP) in a randomized clinical trial. A total of 286 implants were placed in the augmented bone, and their evolution was followed up for a period of 24 months. In order to investigate on a histological level and any adjunctive effects, we performed an ancillary study in five edentulous patients with a symmetrical severely resorbed maxilla. In these patients, a bilateral sinus augmentation was randomly performed using ABB or ABB + PRP in a split-mouth design, and after 6 months, bone biopsies were taken from the implant sites for histological and histomorphometric analysis. Results: Overall, 96.2% of ABB and 98.6% of ABB+PRP implant success were obtained during the monitoring period and differences were not found between sites grafted with and without PRP in the 87 patients studied. Densitometry assessments and graft resorption were similar in both experimental groups. However, the histological and histomorphometrical analysis in the five edentulous patients revealed that bone augmentation was significantly higher in sites treated with ABB+PRP (p ≤ 0.05). Another outcome from our study is that the lack of initial bone support (p ≤ 0.05) and smoking (p = 0.05) appeared to have a negative effect on the treatment success, which was accentuated when both circumstances coincided. Conclusions: PRP is not a determining factor for implant survival in sinus lifting procedures. However, this study revealed that PRP can improve the osteoconductive properties of ABB by increasing the volume of new bone formed. Moreover, in sinus augmentation procedures the implant's survival rate appears to be more influenced by the residual bone height or by tobacco than by the type of bone graft.</EA>
<CC>002B10C02</CC>
<FD>Thrombocyte; Plasma sanguin; Rhytidoplastie; Essai clinique; Bovin; Os; Régénération; Plancher; Dentisterie</FD>
<FG>Artiodactyla; Ungulata; Mammalia; Vertebrata</FG>
<ED>Platelet; Blood plasma; Lifting; Clinical trial; Bovine; Bone; Regeneration; Floor; Dentistry</ED>
<EG>Artiodactyla; Ungulata; Mammalia; Vertebrata</EG>
<SD>Trombocito; Plasma sanguíneo; Ritidoplastia; Ensayo clínico; Bovino; Hueso; Regeneración; Piso; Odontología</SD>
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Effect of platelet-rich plasma on sinus lifting: a randomized- controlled clinical trial

Effect of platelet-rich plasma on sinus lifting: a randomized- controlled clinical trial

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