Comparative finite-element analysis: a single computational modelling method can estimate the mechanical properties of porcine and human vertebrae
Identifieur interne : 000B98 ( Ncbi/Merge ); précédent : 000B97; suivant : 000B99Comparative finite-element analysis: a single computational modelling method can estimate the mechanical properties of porcine and human vertebrae
Auteurs : K. Robson Brown [Royaume-Uni] ; S. Tarsuslugil [Royaume-Uni] ; V. N. Wijayathunga [Royaume-Uni] ; R. K. Wilcox [Royaume-Uni]Source :
- Journal of the Royal Society Interface [ 1742-5689 ] ; 2014.
Abstract
Significant advances in the functional analysis of musculoskeletal systems require the development of modelling techniques with improved focus, accuracy and validity. This need is particularly visible in the fields, such as palaeontology, where unobservable parameters may lie at the heart of the most interesting research questions, and where models and simulations may provide some of the most innovative solutions. Here, we report on the development of a computational modelling method to generate estimates of the mechanical properties of vertebral bone across two living species, using elderly human and juvenile porcine specimens as cases with very different levels of bone volume fraction and mineralization. This study is presented in two parts; part I presents the computational model development and validation, and part II the virtual loading regime and results. This work paves the way for the future estimation of mechanical properties in fossil mammalian bone.
Url:
DOI: 10.1098/rsif.2014.0186
PubMed: 24718451
PubMed Central: 4006260
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<front><div type="abstract" xml:lang="en"><p>Significant advances in the functional analysis of musculoskeletal systems require the development of modelling techniques with improved focus, accuracy and validity. This need is particularly visible in the fields, such as palaeontology, where unobservable parameters may lie at the heart of the most interesting research questions, and where models and simulations may provide some of the most innovative solutions. Here, we report on the development of a computational modelling method to generate estimates of the mechanical properties of vertebral bone across two living species, using elderly human and juvenile porcine specimens as cases with very different levels of bone volume fraction and mineralization. This study is presented in two parts; part I presents the computational model development and validation, and part II the virtual loading regime and results. This work paves the way for the future estimation of mechanical properties in fossil mammalian bone.</p>
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<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Van Rietbergen, B" uniqKey="Van Rietbergen B">B van Rietbergen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Dumont, Er" uniqKey="Dumont E">ER Dumont</name>
</author>
<author><name sortKey="Grosse, Ir" uniqKey="Grosse I">IR Grosse</name>
</author>
<author><name sortKey="Slater, Gj" uniqKey="Slater G">GJ Slater</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Dechow, Pc" uniqKey="Dechow P">PC Dechow</name>
</author>
<author><name sortKey="Wang, Q" uniqKey="Wang Q">Q Wang</name>
</author>
<author><name sortKey="Peterson, J" uniqKey="Peterson J">J Peterson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rayfield, Ej" uniqKey="Rayfield E">EJ Rayfield</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hutchinson, Jr" uniqKey="Hutchinson J">JR Hutchinson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tseng, Zj" uniqKey="Tseng Z">ZJ Tseng</name>
</author>
<author><name sortKey="Mcnitt Gray, Jl" uniqKey="Mcnitt Gray J">JL McNitt-Gray</name>
</author>
<author><name sortKey="Flaschner, H" uniqKey="Flaschner H">H Flaschner</name>
</author>
<author><name sortKey="Wang, X" uniqKey="Wang X">X Wang</name>
</author>
<author><name sortKey="Enciso, R" uniqKey="Enciso R">R Enciso</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Richmond, Bg" uniqKey="Richmond B">BG Richmond</name>
</author>
<author><name sortKey="Wright, Bw" uniqKey="Wright B">BW Wright</name>
</author>
<author><name sortKey="Grosse, I" uniqKey="Grosse I">I Grosse</name>
</author>
<author><name sortKey="Dechow, Pc" uniqKey="Dechow P">PC Dechow</name>
</author>
<author><name sortKey="Ross, Cf" uniqKey="Ross C">CF Ross</name>
</author>
<author><name sortKey="Spencer, Ma" uniqKey="Spencer M">MA Spencer</name>
</author>
<author><name sortKey="Strait, Ds" uniqKey="Strait D">DS Strait</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rayfield, Ej" uniqKey="Rayfield E">EJ Rayfield</name>
</author>
<author><name sortKey="Bright, J" uniqKey="Bright J">J Bright</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Soons, J" uniqKey="Soons J">J Soons</name>
</author>
<author><name sortKey="Herrel, A" uniqKey="Herrel A">A Herrel</name>
</author>
<author><name sortKey="Genbrugge, A" uniqKey="Genbrugge A">A Genbrugge</name>
</author>
<author><name sortKey="Aerts, P" uniqKey="Aerts P">P Aerts</name>
</author>
<author><name sortKey="Podos, J" uniqKey="Podos J">J Podos</name>
</author>
<author><name sortKey="Adriaens, D" uniqKey="Adriaens D">D Adriaens</name>
</author>
<author><name sortKey="De Witte, Y" uniqKey="De Witte Y">Y de Witte</name>
</author>
<author><name sortKey="Jacobs, P" uniqKey="Jacobs P">P Jacobs</name>
</author>
<author><name sortKey="Dirckx, J" uniqKey="Dirckx J">J Dirckx</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Anderson, Psl" uniqKey="Anderson P">PSL Anderson</name>
</author>
<author><name sortKey="Rayfield, Ej" uniqKey="Rayfield E">EJ Rayfield</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Pangiotopoulou, O" uniqKey="Pangiotopoulou O">O Pangiotopoulou</name>
</author>
<author><name sortKey="Wilshin, Sd" uniqKey="Wilshin S">SD Wilshin</name>
</author>
<author><name sortKey="Rayfield, Ej" uniqKey="Rayfield E">EJ Rayfield</name>
</author>
<author><name sortKey="Shefelbine, Sj" uniqKey="Shefelbine S">SJ Shefelbine</name>
</author>
<author><name sortKey="Hutchinson, Jr" uniqKey="Hutchinson J">JR Hutchinson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Soons, J" uniqKey="Soons J">J Soons</name>
</author>
<author><name sortKey="Herrel, A" uniqKey="Herrel A">A Herrel</name>
</author>
<author><name sortKey="Genbrugge, A" uniqKey="Genbrugge A">A Genbrugge</name>
</author>
<author><name sortKey="Adriaens, D" uniqKey="Adriaens D">D Adriaens</name>
</author>
<author><name sortKey="Aerts, P" uniqKey="Aerts P">P Aerts</name>
</author>
<author><name sortKey="Dirckx, J" uniqKey="Dirckx J">J Dirckx</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wijayathunga, Vn" uniqKey="Wijayathunga V">VN Wijayathunga</name>
</author>
<author><name sortKey="Jones, Ac" uniqKey="Jones A">AC Jones</name>
</author>
<author><name sortKey="Oakland, Rj" uniqKey="Oakland R">RJ Oakland</name>
</author>
<author><name sortKey="Furtado, Nr" uniqKey="Furtado N">NR Furtado</name>
</author>
<author><name sortKey="Hall, Rm" uniqKey="Hall R">RM Hall</name>
</author>
<author><name sortKey="Wilcox, Rk" uniqKey="Wilcox R">RK Wilcox</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Anderson, Psl" uniqKey="Anderson P">PSL Anderson</name>
</author>
<author><name sortKey="Bright, Ja" uniqKey="Bright J">JA Bright</name>
</author>
<author><name sortKey="Gill, Pg" uniqKey="Gill P">PG Gill</name>
</author>
<author><name sortKey="Palmer, C" uniqKey="Palmer C">C Palmer</name>
</author>
<author><name sortKey="Rayfield, Ej" uniqKey="Rayfield E">EJ Rayfield</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Dath, R" uniqKey="Dath R">R Dath</name>
</author>
<author><name sortKey="Ebinesan, Ad" uniqKey="Ebinesan A">AD Ebinesan</name>
</author>
<author><name sortKey="Porter, Km" uniqKey="Porter K">KM Porter</name>
</author>
<author><name sortKey="Miles, Aw" uniqKey="Miles A">AW Miles</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wilke, H J" uniqKey="Wilke H">H-J Wilke</name>
</author>
<author><name sortKey="Geppert, J" uniqKey="Geppert J">J Geppert</name>
</author>
<author><name sortKey="Kienle, A" uniqKey="Kienle A">A Kienle</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tarsuslugil, Sm" uniqKey="Tarsuslugil S">SM Tarsuslugil</name>
</author>
<author><name sortKey="O Hara, Rm" uniqKey="O Hara R">RM O'Hara</name>
</author>
<author><name sortKey="Dunne, Nj" uniqKey="Dunne N">NJ Dunne</name>
</author>
<author><name sortKey="Buchanan, Fj" uniqKey="Buchanan F">FJ Buchanan</name>
</author>
<author><name sortKey="Orr, Jf" uniqKey="Orr J">JF Orr</name>
</author>
<author><name sortKey="Barton, Dc" uniqKey="Barton D">DC Barton</name>
</author>
<author><name sortKey="Wilcox, Rk" uniqKey="Wilcox R">RK Wilcox</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wilcox, Rk" uniqKey="Wilcox R">RK Wilcox</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jones, Ac" uniqKey="Jones A">AC Jones</name>
</author>
<author><name sortKey="Wilcox, Rk" uniqKey="Wilcox R">RK Wilcox</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Liu, Xs" uniqKey="Liu X">XS Liu</name>
</author>
<author><name sortKey="Sajda, P" uniqKey="Sajda P">P Sajda</name>
</author>
<author><name sortKey="Saha, Pk" uniqKey="Saha P">PK Saha</name>
</author>
<author><name sortKey="Wehrli, Fw" uniqKey="Wehrli F">FW Wehrli</name>
</author>
<author><name sortKey="Guo, Xe" uniqKey="Guo X">XE Guo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kim, D G" uniqKey="Kim D">D-G Kim</name>
</author>
<author><name sortKey="Christpherson, Gt" uniqKey="Christpherson G">GT Christpherson</name>
</author>
<author><name sortKey="Dong, Xn" uniqKey="Dong X">XN Dong</name>
</author>
<author><name sortKey="Fyrie, Dp" uniqKey="Fyrie D">DP Fyrie</name>
</author>
<author><name sortKey="Yeni, Yn" uniqKey="Yeni Y">YN Yeni</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Inui, A" uniqKey="Inui A">A Inui</name>
</author>
<author><name sortKey="Itamoto, K" uniqKey="Itamoto K">K Itamoto</name>
</author>
<author><name sortKey="Takuma, T" uniqKey="Takuma T">T Takuma</name>
</author>
<author><name sortKey="Tsutsumi, H" uniqKey="Tsutsumi H">H Tsutsumi</name>
</author>
<author><name sortKey="Tanigawa, M" uniqKey="Tanigawa M">M Tanigawa</name>
</author>
<author><name sortKey="Hayasaki, M" uniqKey="Hayasaki M">M Hayasaki</name>
</author>
<author><name sortKey="Taura, Y" uniqKey="Taura Y">Y Taura</name>
</author>
<author><name sortKey="Mamba, K" uniqKey="Mamba K">K Mamba</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Eberle, S" uniqKey="Eberle S">S Eberle</name>
</author>
<author><name sortKey="Gottlinger, M" uniqKey="Gottlinger M">M Göttlinger</name>
</author>
<author><name sortKey="Augat, P" uniqKey="Augat P">P Augat</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Cong, A" uniqKey="Cong A">A Cong</name>
</author>
<author><name sortKey="Buijs, Jod" uniqKey="Buijs J">JOD Buijs</name>
</author>
<author><name sortKey="Dragomir Daescu, D" uniqKey="Dragomir Daescu D">D Dragomir-Daescu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Adams, Ma" uniqKey="Adams M">MA Adams</name>
</author>
<author><name sortKey="Hutton, Wc" uniqKey="Hutton W">WC Hutton</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Robson Brown, K" uniqKey="Robson Brown K">K Robson Brown</name>
</author>
<author><name sortKey="Pollintine, P" uniqKey="Pollintine P">P Pollintine</name>
</author>
<author><name sortKey="Adams, Ma" uniqKey="Adams M">MA Adams</name>
</author>
</analytic>
</biblStruct>
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<title-group><article-title>Comparative finite-element analysis: a single computational modelling method can estimate the mechanical properties of porcine and human vertebrae</article-title>
<alt-title alt-title-type="short">Comparative finite-element analysis: a single computational modelling method can estimate the mechanical properties of porcine and human vertebrae</alt-title>
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<contrib-group><contrib contrib-type="author"><name><surname>Robson Brown</surname>
<given-names>K.</given-names>
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<addr-line>Institute of Medical and Biological Engineering, School of Mechanical Engineering</addr-line>
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,<addr-line>Leeds LS2 9JT</addr-line>
,<country>UK</country>
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<author-notes><corresp id="cor1">e-mail: <email>kate.robson-brown@bristol.ac.uk</email>
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<pub-date pub-type="ppub"><day>6</day>
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</pub-date>
<pmc-comment> PMC Release delay is 0 months and 0 days and was based on the
. </pmc-comment>
<volume>11</volume>
<issue>95</issue>
<elocation-id>20140186</elocation-id>
<history><date date-type="received"><day>21</day>
<month>2</month>
<year>2014</year>
</date>
<date date-type="accepted"><day>14</day>
<month>3</month>
<year>2014</year>
</date>
</history>
<permissions><copyright-statement></copyright-statement>
<copyright-year>2014</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/3.0/"><license-p>© 2014 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/3.0/">http://creativecommons.org/licenses/by/3.0/</ext-link>
, which permits unrestricted use, provided the original author and source are credited.</license-p>
</license>
</permissions>
<self-uri content-type="pdf" xlink:type="simple" xlink:href="rsif20140186.pdf"></self-uri>
<abstract><p>Significant advances in the functional analysis of musculoskeletal systems require the development of modelling techniques with improved focus, accuracy and validity. This need is particularly visible in the fields, such as palaeontology, where unobservable parameters may lie at the heart of the most interesting research questions, and where models and simulations may provide some of the most innovative solutions. Here, we report on the development of a computational modelling method to generate estimates of the mechanical properties of vertebral bone across two living species, using elderly human and juvenile porcine specimens as cases with very different levels of bone volume fraction and mineralization. This study is presented in two parts; part I presents the computational model development and validation, and part II the virtual loading regime and results. This work paves the way for the future estimation of mechanical properties in fossil mammalian bone.</p>
</abstract>
<kwd-group><kwd>finite-element analysis</kwd>
<kwd>vertebra</kwd>
<kwd>bone mechanics</kwd>
<kwd>porcine</kwd>
<kwd>human</kwd>
<kwd>comparative</kwd>
</kwd-group>
<custom-meta-group><custom-meta><meta-name>cover-date</meta-name>
<meta-value>June 6, 2014</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
</pmc>
<affiliations><list><country><li>Royaume-Uni</li>
</country>
</list>
<tree><country name="Royaume-Uni"><noRegion><name sortKey="Robson Brown, K" sort="Robson Brown, K" uniqKey="Robson Brown K" first="K." last="Robson Brown">K. Robson Brown</name>
</noRegion>
<name sortKey="Tarsuslugil, S" sort="Tarsuslugil, S" uniqKey="Tarsuslugil S" first="S." last="Tarsuslugil">S. Tarsuslugil</name>
<name sortKey="Wijayathunga, V N" sort="Wijayathunga, V N" uniqKey="Wijayathunga V" first="V. N." last="Wijayathunga">V. N. Wijayathunga</name>
<name sortKey="Wilcox, R K" sort="Wilcox, R K" uniqKey="Wilcox R" first="R. K." last="Wilcox">R. K. Wilcox</name>
</country>
</tree>
</affiliations>
</record>
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