Revisiting peri-implant soft tissue – histopathological study of the peri-implant soft tissue
Identifieur interne : 000972 ( Ncbi/Checkpoint ); précédent : 000971; suivant : 000973Revisiting peri-implant soft tissue – histopathological study of the peri-implant soft tissue
Auteurs : Eduarda Silva [Portugal] ; Sérgio Félix [Portugal] ; Alberto Rodriguez-Archilla [Espagne] ; Pedro Oliveira [Portugal] ; José Martins Dos Santos [Portugal]Source :
- International Journal of Clinical and Experimental Pathology [ 1936-2625 ] ; 2014.
Abstract
Peri-implant soft tissues are essential for osseointegration. The peri-implant mucosa may lack vascular supply, and histological observation, even without plaque, shows the presence of inflammatory cells. The objectives of this study were to assess the histopathological changes of the epithelium and connective tissue around the implant. Twenty patients of both genders were studied. Twelve weeks after implant placement, fragments of peri-implant gingival sulcus were harvested and processed for light microscopy. Group I (10): without clinical inflammatory signs (control); Group II (10): with clinical inflammatory signs. Histopathological parameters were analyzed and classified in 3 grades: mild, moderate or severe (grade 1, 2 or 3). Control group showed only slight changes, grade 1. In group II we found edema with moderate to severe cellular and nuclear changes. There are more women than men with all grades of inflammation. All patients with moderate edema are male and all patients with severe edema are female. A significant association (p=0.007) exists between these two variables. Significant differences were found when comparing the degree of inflammation with nuclear alterations (p=0.001) and the same results when comparing the degree of edema and nuclear changes (p<0.001). This study demonstrates that clinical examination can be used, with a small margin of error, to monitor and control the state of the peri-implant mucosa. In clinics the predisposition of female patients to greater degree of edema and inflammation should be accounted for.
Url:
PubMed: 24551281
PubMed Central: 3925905
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000323
- to stream Pmc, to step Curation: 000323
- to stream Pmc, to step Checkpoint: 000116
- to stream Ncbi, to step Merge: 000972
- to stream Ncbi, to step Curation: 000972
Links to Exploration step
PMC:3925905Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Revisiting peri-implant soft tissue – histopathological study of the peri-implant soft tissue</title>
<author><name sortKey="Silva, Eduarda" sort="Silva, Eduarda" uniqKey="Silva E" first="Eduarda" last="Silva">Eduarda Silva</name>
<affiliation wicri:level="1"><nlm:aff id="au1"><institution>Center for Interdisciplinary Research Egas Moniz, Health Sciences Institute</institution>
<addr-line>Monte de Caparica, Portugal</addr-line>
</nlm:aff>
<country xml:lang="fr">Portugal</country>
<wicri:regionArea>Monte de Caparica</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Felix, Sergio" sort="Felix, Sergio" uniqKey="Felix S" first="Sérgio" last="Félix">Sérgio Félix</name>
<affiliation wicri:level="1"><nlm:aff id="au1"><institution>Center for Interdisciplinary Research Egas Moniz, Health Sciences Institute</institution>
<addr-line>Monte de Caparica, Portugal</addr-line>
</nlm:aff>
<country xml:lang="fr">Portugal</country>
<wicri:regionArea>Monte de Caparica</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rodriguez Archilla, Alberto" sort="Rodriguez Archilla, Alberto" uniqKey="Rodriguez Archilla A" first="Alberto" last="Rodriguez-Archilla">Alberto Rodriguez-Archilla</name>
<affiliation wicri:level="1"><nlm:aff id="au2"><institution>School of Dentistry, University of Granada</institution>
<addr-line>Granada, Spain</addr-line>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Granada</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Oliveira, Pedro" sort="Oliveira, Pedro" uniqKey="Oliveira P" first="Pedro" last="Oliveira">Pedro Oliveira</name>
<affiliation wicri:level="1"><nlm:aff id="au1"><institution>Center for Interdisciplinary Research Egas Moniz, Health Sciences Institute</institution>
<addr-line>Monte de Caparica, Portugal</addr-line>
</nlm:aff>
<country xml:lang="fr">Portugal</country>
<wicri:regionArea>Monte de Caparica</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Martins Dos Santos, Jose" sort="Martins Dos Santos, Jose" uniqKey="Martins Dos Santos J" first="José" last="Martins Dos Santos">José Martins Dos Santos</name>
<affiliation wicri:level="1"><nlm:aff id="au1"><institution>Center for Interdisciplinary Research Egas Moniz, Health Sciences Institute</institution>
<addr-line>Monte de Caparica, Portugal</addr-line>
</nlm:aff>
<country xml:lang="fr">Portugal</country>
<wicri:regionArea>Monte de Caparica</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">24551281</idno>
<idno type="pmc">3925905</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925905</idno>
<idno type="RBID">PMC:3925905</idno>
<date when="2014">2014</date>
<idno type="wicri:Area/Pmc/Corpus">000323</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000323</idno>
<idno type="wicri:Area/Pmc/Curation">000323</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000323</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000116</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000116</idno>
<idno type="wicri:Area/Ncbi/Merge">000972</idno>
<idno type="wicri:Area/Ncbi/Curation">000972</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000972</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Revisiting peri-implant soft tissue – histopathological study of the peri-implant soft tissue</title>
<author><name sortKey="Silva, Eduarda" sort="Silva, Eduarda" uniqKey="Silva E" first="Eduarda" last="Silva">Eduarda Silva</name>
<affiliation wicri:level="1"><nlm:aff id="au1"><institution>Center for Interdisciplinary Research Egas Moniz, Health Sciences Institute</institution>
<addr-line>Monte de Caparica, Portugal</addr-line>
</nlm:aff>
<country xml:lang="fr">Portugal</country>
<wicri:regionArea>Monte de Caparica</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Felix, Sergio" sort="Felix, Sergio" uniqKey="Felix S" first="Sérgio" last="Félix">Sérgio Félix</name>
<affiliation wicri:level="1"><nlm:aff id="au1"><institution>Center for Interdisciplinary Research Egas Moniz, Health Sciences Institute</institution>
<addr-line>Monte de Caparica, Portugal</addr-line>
</nlm:aff>
<country xml:lang="fr">Portugal</country>
<wicri:regionArea>Monte de Caparica</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rodriguez Archilla, Alberto" sort="Rodriguez Archilla, Alberto" uniqKey="Rodriguez Archilla A" first="Alberto" last="Rodriguez-Archilla">Alberto Rodriguez-Archilla</name>
<affiliation wicri:level="1"><nlm:aff id="au2"><institution>School of Dentistry, University of Granada</institution>
<addr-line>Granada, Spain</addr-line>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Granada</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Oliveira, Pedro" sort="Oliveira, Pedro" uniqKey="Oliveira P" first="Pedro" last="Oliveira">Pedro Oliveira</name>
<affiliation wicri:level="1"><nlm:aff id="au1"><institution>Center for Interdisciplinary Research Egas Moniz, Health Sciences Institute</institution>
<addr-line>Monte de Caparica, Portugal</addr-line>
</nlm:aff>
<country xml:lang="fr">Portugal</country>
<wicri:regionArea>Monte de Caparica</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Martins Dos Santos, Jose" sort="Martins Dos Santos, Jose" uniqKey="Martins Dos Santos J" first="José" last="Martins Dos Santos">José Martins Dos Santos</name>
<affiliation wicri:level="1"><nlm:aff id="au1"><institution>Center for Interdisciplinary Research Egas Moniz, Health Sciences Institute</institution>
<addr-line>Monte de Caparica, Portugal</addr-line>
</nlm:aff>
<country xml:lang="fr">Portugal</country>
<wicri:regionArea>Monte de Caparica</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">International Journal of Clinical and Experimental Pathology</title>
<idno type="eISSN">1936-2625</idno>
<imprint><date when="2014">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Peri-implant soft tissues are essential for osseointegration. The peri-implant mucosa may lack vascular supply, and histological observation, even without plaque, shows the presence of inflammatory cells. The objectives of this study were to assess the histopathological changes of the epithelium and connective tissue around the implant. Twenty patients of both genders were studied. Twelve weeks after implant placement, fragments of peri-implant gingival sulcus were harvested and processed for light microscopy. Group I (10): without clinical inflammatory signs (control); Group II (10): with clinical inflammatory signs. Histopathological parameters were analyzed and classified in 3 grades: mild, moderate or severe (grade 1, 2 or 3). Control group showed only slight changes, grade 1. In group II we found edema with moderate to severe cellular and nuclear changes. There are more women than men with all grades of inflammation. All patients with moderate edema are male and all patients with severe edema are female. A significant association (p=0.007) exists between these two variables. Significant differences were found when comparing the degree of inflammation with nuclear alterations (p=0.001) and the same results when comparing the degree of edema and nuclear changes (p<0.001). This study demonstrates that clinical examination can be used, with a small margin of error, to monitor and control the state of the peri-implant mucosa. In clinics the predisposition of female patients to greater degree of edema and inflammation should be accounted for.</p>
</div>
</front>
</TEI>
<affiliations><list><country><li>Espagne</li>
<li>Portugal</li>
</country>
</list>
<tree><country name="Portugal"><noRegion><name sortKey="Silva, Eduarda" sort="Silva, Eduarda" uniqKey="Silva E" first="Eduarda" last="Silva">Eduarda Silva</name>
</noRegion>
<name sortKey="Felix, Sergio" sort="Felix, Sergio" uniqKey="Felix S" first="Sérgio" last="Félix">Sérgio Félix</name>
<name sortKey="Martins Dos Santos, Jose" sort="Martins Dos Santos, Jose" uniqKey="Martins Dos Santos J" first="José" last="Martins Dos Santos">José Martins Dos Santos</name>
<name sortKey="Oliveira, Pedro" sort="Oliveira, Pedro" uniqKey="Oliveira P" first="Pedro" last="Oliveira">Pedro Oliveira</name>
</country>
<country name="Espagne"><noRegion><name sortKey="Rodriguez Archilla, Alberto" sort="Rodriguez Archilla, Alberto" uniqKey="Rodriguez Archilla A" first="Alberto" last="Rodriguez-Archilla">Alberto Rodriguez-Archilla</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV1/Data/Ncbi/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000972 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd -nk 000972 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= EdenteV1 |flux= Ncbi |étape= Checkpoint |type= RBID |clé= PMC:3925905 |texte= Revisiting peri-implant soft tissue – histopathological study of the peri-implant soft tissue }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/RBID.i -Sk "pubmed:24551281" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd \ | NlmPubMed2Wicri -a EdenteV1
This area was generated with Dilib version V0.6.33. |