Peroxisome proliferator‐activated receptor (PPAR) γ polymorphism, vitamin D, bone mineral density and periodontitis in postmenopausal women
Identifieur interne : 001573 ( Main/Exploration ); précédent : 001572; suivant : 001574Peroxisome proliferator‐activated receptor (PPAR) γ polymorphism, vitamin D, bone mineral density and periodontitis in postmenopausal women
Auteurs : Y. Wang [Japon] ; N. Sugita [Japon] ; A. Yoshihara [Japon] ; M. Iwasaki [Japon] ; H. Miyazaki [Japon] ; K. Nakamura [Japon] ; H. Yoshie [Japon]Source :
- Oral Diseases [ 1354-523X ] ; 2013-07.
English descriptors
- KwdEn :
- Alcohol consumption, Allele, Allele carriers, Body mass index, Bone metabolism, Bone mineral density, Calcium supplement, Clin periodontol, Clinical attachment loss, Dental sciences, Dietary intake, Genotype, Niigata, Niigata university graduate school, Oral diseases, Osteoporosis, Periodontal, Periodontal disease, Periodontal parameters, Periodontitis, Periodontol, Peroxisome, Peroxisome receptor, Polymorphism, Postmenopausal, Postmenopausal japanese women, Postmenopausal women, Pparc, Pparc polymorphism, Pregnant japanese women, Present study, Previous study, Receptor, Serum level, Serum levels.
- Teeft :
- Alcohol consumption, Allele, Allele carriers, Body mass index, Bone metabolism, Bone mineral density, Calcium supplement, Clin periodontol, Clinical attachment loss, Dental sciences, Dietary intake, Genotype, Niigata, Niigata university graduate school, Oral diseases, Osteoporosis, Periodontal, Periodontal disease, Periodontal parameters, Periodontitis, Periodontol, Peroxisome, Peroxisome receptor, Polymorphism, Postmenopausal, Postmenopausal japanese women, Postmenopausal women, Pparc, Pparc polymorphism, Pregnant japanese women, Present study, Previous study, Receptor, Serum level, Serum levels.
Abstract
PPARg regulates bone metabolism and inflammation. Our previous study suggested PPARg Pro12Ala polymorphism to represent a susceptibility factor for periodontitis in pregnant Japanese women. Several recent papers have drawn attention to a possible link between low bone mineral density (BMD) and periodontitis in postmenopausal women. Since the pathogenesis for both involve bone remodeling, they might share common risk factors such as gene polymorphisms and vitamin D level. The present study investigated possible associations between the PPARgPro12Ala polymorphism, periodontitis, BMD and serum 25(OH)D in postmenopausal Japanese women.
Url:
DOI: 10.1111/odi.12032
Affiliations:
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Le document en format XML
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<term>Bone mineral density</term>
<term>Calcium supplement</term>
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<term>Dietary intake</term>
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<term>Periodontal disease</term>
<term>Periodontal parameters</term>
<term>Periodontitis</term>
<term>Periodontol</term>
<term>Peroxisome</term>
<term>Peroxisome receptor</term>
<term>Polymorphism</term>
<term>Postmenopausal</term>
<term>Postmenopausal japanese women</term>
<term>Postmenopausal women</term>
<term>Pparc</term>
<term>Pparc polymorphism</term>
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<term>Calcium supplement</term>
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<front><div type="abstract">PPARg regulates bone metabolism and inflammation. Our previous study suggested PPARg Pro12Ala polymorphism to represent a susceptibility factor for periodontitis in pregnant Japanese women. Several recent papers have drawn attention to a possible link between low bone mineral density (BMD) and periodontitis in postmenopausal women. Since the pathogenesis for both involve bone remodeling, they might share common risk factors such as gene polymorphisms and vitamin D level. The present study investigated possible associations between the PPARgPro12Ala polymorphism, periodontitis, BMD and serum 25(OH)D in postmenopausal Japanese women.</div>
</front>
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