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Candida colonisation and the efficacy of chlorhexidine gluconate on soft silicone‐lined dentures of diabetic and non‐diabetic patients

Identifieur interne : 000002 ( Istex/Corpus ); précédent : 000001; suivant : 000003

Candida colonisation and the efficacy of chlorhexidine gluconate on soft silicone‐lined dentures of diabetic and non‐diabetic patients

Auteurs : Sneha S. Mantri ; Rambhau D. Parkhedkar ; Shivkumar P. Mantri

Source :

RBID : ISTEX:0108C2CFCE5D013EF459065661C8E3D6A17DC156

English descriptors

Abstract

The aim of this study was to evaluate Candida colonisation in the dentures with silicone soft liner in diabetic and non‐diabetic patients and to assess the antifungal efficacy of chlorhexidine gluconate on Candida colonies.

Url:
DOI: 10.1111/ger.12012

Links to Exploration step

ISTEX:0108C2CFCE5D013EF459065661C8E3D6A17DC156

Le document en format XML

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<hi rend="fc">C</hi>
andida colonisation in the dentures with silicone soft liner in diabetic and non‐diabetic patients and to assess the antifungal efficacy of chlorhexidine gluconate on
<hi rend="fc">C</hi>
andida colonies.</p>
Materials and methods
<p>Thirty patients with resorbed ridges, fifteen each in the diabetic and non‐diabetic group, were selected. The mandibular denture of each patient was lined with heat‐polymerised silicone resilient liner. Patients were instructed to clean the dentures with soap water and brush. Samples from the fitting surface of mandibular dentures were collected at 15, 21 and 30 days. Subsequently, samples were collected at 15, 21 and 30 days, after cleaning the dentures with a detergent solution of 4% chlorhexidine gluconate, and incubated for the evaluation of
<hi rend="fc">C</hi>
andida growth. These data were subjected to statistical analysis by
<hi rend="fc">M</hi>
ann–
<hi rend="fc">W</hi>
hitney
<hi rend="italic">
<hi rend="fc">U</hi>
</hi>
‐test.</p>
Results
<p>Normal oral flora in diabetics and non‐diabetics showed no difference (
<hi rend="italic">p</hi>
 > 0.05). The density of colonies increased after 21 and 30 days in diabetic patients (
<hi rend="italic">p</hi>
 < 0.05). Number of
<hi rend="fc">C</hi>
andida colonies significantly reduced in both the groups after 21 and 30 days of cleaning the dentures with 4% chlorhexidine gluconate (
<hi rend="italic">p</hi>
 < 0.05).</p>
Conclusion
<p>Dentures with silicone resilient liner exhibit increased
<hi rend="fc">C</hi>
andida growth in diabetic patients. Four per cent chlorhexidine gluconate solution effectively disinfects these dentures.</p>
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<line>Tel.: 0761 2601109</line>
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<email>snehamantri24@gmail.com</email>
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<fc>C</fc>
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<fc>C</fc>
andida colonies.</p>
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<p>Thirty patients with resorbed ridges, fifteen each in the diabetic and non‐diabetic group, were selected. The mandibular denture of each patient was lined with heat‐polymerised silicone resilient liner. Patients were instructed to clean the dentures with soap water and brush. Samples from the fitting surface of mandibular dentures were collected at 15, 21 and 30 days. Subsequently, samples were collected at 15, 21 and 30 days, after cleaning the dentures with a detergent solution of 4% chlorhexidine gluconate, and incubated for the evaluation of
<fc>C</fc>
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<p>Normal oral flora in diabetics and non‐diabetics showed no difference (
<i>p</i>
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<i>p</i>
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<fc>C</fc>
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<p>Dentures with silicone resilient liner exhibit increased
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<abstract>The aim of this study was to evaluate Candida colonisation in the dentures with silicone soft liner in diabetic and non‐diabetic patients and to assess the antifungal efficacy of chlorhexidine gluconate on Candida colonies.</abstract>
<abstract>Thirty patients with resorbed ridges, fifteen each in the diabetic and non‐diabetic group, were selected. The mandibular denture of each patient was lined with heat‐polymerised silicone resilient liner. Patients were instructed to clean the dentures with soap water and brush. Samples from the fitting surface of mandibular dentures were collected at 15, 21 and 30 days. Subsequently, samples were collected at 15, 21 and 30 days, after cleaning the dentures with a detergent solution of 4% chlorhexidine gluconate, and incubated for the evaluation of Candida growth. These data were subjected to statistical analysis by Mann–Whitney U‐test.</abstract>
<abstract>Normal oral flora in diabetics and non‐diabetics showed no difference (p > 0.05). The density of colonies increased after 21 and 30 days in diabetic patients (p < 0.05). Number of Candida colonies significantly reduced in both the groups after 21 and 30 days of cleaning the dentures with 4% chlorhexidine gluconate (p < 0.05).</abstract>
<abstract>Dentures with silicone resilient liner exhibit increased Candida growth in diabetic patients. Four per cent chlorhexidine gluconate solution effectively disinfects these dentures.</abstract>
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