Artificial Intelligence Distinguishes COVID-19 from Community Acquired Pneumonia on Chest CT.
Identifieur interne : 000297 ( PubMed/Curation ); précédent : 000296; suivant : 000298Artificial Intelligence Distinguishes COVID-19 from Community Acquired Pneumonia on Chest CT.
Auteurs : Lin Li ; Lixin Qin ; Zeguo Xu ; Youbing Yin ; Xin Wang ; Bin Kong ; Junjie Bai ; Yi Lu ; Zhenghan Fang ; Qi Song ; Kunlin Cao ; Daliang Liu ; Guisheng Wang ; Qizhong Xu ; Xisheng Fang ; Shiqin Zhang ; Juan Xia ; Jun XiaSource :
- Radiology [ 1527-1315 ] ; 2020.
Abstract
Background Coronavirus disease has widely spread all over the world since the beginning of 2020. It is desirable to develop automatic and accurate detection of COVID-19 using chest CT. Purpose To develop a fully automatic framework to detect COVID-19 using chest CT and evaluate its performances. Materials and Methods In this retrospective and multi-center study, a deep learning model, COVID-19 detection neural network (COVNet), was developed to extract visual features from volumetric chest CT exams for the detection of COVID-19. Community acquired pneumonia (CAP) and other non-pneumonia CT exams were included to test the robustness of the model. The datasets were collected from 6 hospitals between August 2016 and February 2020. Diagnostic performance was assessed by the area under the receiver operating characteristic curve (AUC), sensitivity and specificity. Results The collected dataset consisted of 4356 chest CT exams from 3,322 patients. The average age is 49±15 years and there were slightly more male patients than female (1838 vs 1484; p-value=0.29). The per-exam sensitivity and specificity for detecting COVID-19 in the independent test set was 114 of 127 (90% [95% CI: 83%, 94%]) and 294 of 307 (96% [95% CI: 93%, 98%]), respectively, with an AUC of 0.96 (p-value<0.001). The per-exam sensitivity and specificity for detecting CAP in the independent test set was 87% (152 of 175) and 92% (239 of 259), respectively, with an AUC of 0.95 (95% CI: 0.93, 0.97). Conclusions A deep learning model can accurately detect COVID-19 and differentiate it from community acquired pneumonia and other lung diseases.
DOI: 10.1148/radiol.2020200905
PubMed: 32191588
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Lin Li<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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Le document en format XML
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<author><name sortKey="Li, Lin" sort="Li, Lin" uniqKey="Li L" first="Lin" last="Li">Lin Li</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<author><name sortKey="Qin, Lixin" sort="Qin, Lixin" uniqKey="Qin L" first="Lixin" last="Qin">Lixin Qin</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<author><name sortKey="Xu, Zeguo" sort="Xu, Zeguo" uniqKey="Xu Z" first="Zeguo" last="Xu">Zeguo Xu</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<author><name sortKey="Yin, Youbing" sort="Yin, Youbing" uniqKey="Yin Y" first="Youbing" last="Yin">Youbing Yin</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<author><name sortKey="Wang, Xin" sort="Wang, Xin" uniqKey="Wang X" first="Xin" last="Wang">Xin Wang</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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<author><name sortKey="Kong, Bin" sort="Kong, Bin" uniqKey="Kong B" first="Bin" last="Kong">Bin Kong</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
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</author>
<author><name sortKey="Bai, Junjie" sort="Bai, Junjie" uniqKey="Bai J" first="Junjie" last="Bai">Junjie Bai</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Lu, Yi" sort="Lu, Yi" uniqKey="Lu Y" first="Yi" last="Lu">Yi Lu</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Fang, Zhenghan" sort="Fang, Zhenghan" uniqKey="Fang Z" first="Zhenghan" last="Fang">Zhenghan Fang</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Song, Qi" sort="Song, Qi" uniqKey="Song Q" first="Qi" last="Song">Qi Song</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Cao, Kunlin" sort="Cao, Kunlin" uniqKey="Cao K" first="Kunlin" last="Cao">Kunlin Cao</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Liu, Daliang" sort="Liu, Daliang" uniqKey="Liu D" first="Daliang" last="Liu">Daliang Liu</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Wang, Guisheng" sort="Wang, Guisheng" uniqKey="Wang G" first="Guisheng" last="Wang">Guisheng Wang</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Xu, Qizhong" sort="Xu, Qizhong" uniqKey="Xu Q" first="Qizhong" last="Xu">Qizhong Xu</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Fang, Xisheng" sort="Fang, Xisheng" uniqKey="Fang X" first="Xisheng" last="Fang">Xisheng Fang</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Zhang, Shiqin" sort="Zhang, Shiqin" uniqKey="Zhang S" first="Shiqin" last="Zhang">Shiqin Zhang</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Xia, Juan" sort="Xia, Juan" uniqKey="Xia J" first="Juan" last="Xia">Juan Xia</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Xia, Jun" sort="Xia, Jun" uniqKey="Xia J" first="Jun" last="Xia">Jun Xia</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2020">2020</date>
<idno type="RBID">pubmed:32191588</idno>
<idno type="pmid">32191588</idno>
<idno type="doi">10.1148/radiol.2020200905</idno>
<idno type="wicri:Area/PubMed/Corpus">000297</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000297</idno>
<idno type="wicri:Area/PubMed/Curation">000297</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000297</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Artificial Intelligence Distinguishes COVID-19 from Community Acquired Pneumonia on Chest CT.</title>
<author><name sortKey="Li, Lin" sort="Li, Lin" uniqKey="Li L" first="Lin" last="Li">Lin Li</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Qin, Lixin" sort="Qin, Lixin" uniqKey="Qin L" first="Lixin" last="Qin">Lixin Qin</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Xu, Zeguo" sort="Xu, Zeguo" uniqKey="Xu Z" first="Zeguo" last="Xu">Zeguo Xu</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Yin, Youbing" sort="Yin, Youbing" uniqKey="Yin Y" first="Youbing" last="Yin">Youbing Yin</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Wang, Xin" sort="Wang, Xin" uniqKey="Wang X" first="Xin" last="Wang">Xin Wang</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Kong, Bin" sort="Kong, Bin" uniqKey="Kong B" first="Bin" last="Kong">Bin Kong</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Bai, Junjie" sort="Bai, Junjie" uniqKey="Bai J" first="Junjie" last="Bai">Junjie Bai</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Lu, Yi" sort="Lu, Yi" uniqKey="Lu Y" first="Yi" last="Lu">Yi Lu</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Fang, Zhenghan" sort="Fang, Zhenghan" uniqKey="Fang Z" first="Zhenghan" last="Fang">Zhenghan Fang</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Song, Qi" sort="Song, Qi" uniqKey="Song Q" first="Qi" last="Song">Qi Song</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Cao, Kunlin" sort="Cao, Kunlin" uniqKey="Cao K" first="Kunlin" last="Cao">Kunlin Cao</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Liu, Daliang" sort="Liu, Daliang" uniqKey="Liu D" first="Daliang" last="Liu">Daliang Liu</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Wang, Guisheng" sort="Wang, Guisheng" uniqKey="Wang G" first="Guisheng" last="Wang">Guisheng Wang</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Xu, Qizhong" sort="Xu, Qizhong" uniqKey="Xu Q" first="Qizhong" last="Xu">Qizhong Xu</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Fang, Xisheng" sort="Fang, Xisheng" uniqKey="Fang X" first="Xisheng" last="Fang">Xisheng Fang</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Zhang, Shiqin" sort="Zhang, Shiqin" uniqKey="Zhang S" first="Shiqin" last="Zhang">Shiqin Zhang</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Xia, Juan" sort="Xia, Juan" uniqKey="Xia J" first="Juan" last="Xia">Juan Xia</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Xia, Jun" sort="Xia, Jun" uniqKey="Xia J" first="Jun" last="Xia">Jun Xia</name>
<affiliation><nlm:affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</nlm:affiliation>
<wicri:noCountry code="subField">J</wicri:noCountry>
</affiliation>
</author>
</analytic>
<series><title level="j">Radiology</title>
<idno type="eISSN">1527-1315</idno>
<imprint><date when="2020" type="published">2020</date>
</imprint>
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<front><div type="abstract" xml:lang="en">Background Coronavirus disease has widely spread all over the world since the beginning of 2020. It is desirable to develop automatic and accurate detection of COVID-19 using chest CT. Purpose To develop a fully automatic framework to detect COVID-19 using chest CT and evaluate its performances. Materials and Methods In this retrospective and multi-center study, a deep learning model, COVID-19 detection neural network (COVNet), was developed to extract visual features from volumetric chest CT exams for the detection of COVID-19. Community acquired pneumonia (CAP) and other non-pneumonia CT exams were included to test the robustness of the model. The datasets were collected from 6 hospitals between August 2016 and February 2020. Diagnostic performance was assessed by the area under the receiver operating characteristic curve (AUC), sensitivity and specificity. Results The collected dataset consisted of 4356 chest CT exams from 3,322 patients. The average age is 49±15 years and there were slightly more male patients than female (1838 vs 1484; p-value=0.29). The per-exam sensitivity and specificity for detecting COVID-19 in the independent test set was 114 of 127 (90% [95% CI: 83%, 94%]) and 294 of 307 (96% [95% CI: 93%, 98%]), respectively, with an AUC of 0.96 (p-value<0.001). The per-exam sensitivity and specificity for detecting CAP in the independent test set was 87% (152 of 175) and 92% (239 of 259), respectively, with an AUC of 0.95 (95% CI: 0.93, 0.97). Conclusions A deep learning model can accurately detect COVID-19 and differentiate it from community acquired pneumonia and other lung diseases.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">32191588</PMID>
<DateRevised><Year>2020</Year>
<Month>03</Month>
<Day>19</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1527-1315</ISSN>
<JournalIssue CitedMedium="Internet"><PubDate><Year>2020</Year>
<Month>Mar</Month>
<Day>19</Day>
</PubDate>
</JournalIssue>
<Title>Radiology</Title>
<ISOAbbreviation>Radiology</ISOAbbreviation>
</Journal>
<ArticleTitle>Artificial Intelligence Distinguishes COVID-19 from Community Acquired Pneumonia on Chest CT.</ArticleTitle>
<Pagination><MedlinePgn>200905</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1148/radiol.2020200905</ELocationID>
<Abstract><AbstractText>Background Coronavirus disease has widely spread all over the world since the beginning of 2020. It is desirable to develop automatic and accurate detection of COVID-19 using chest CT. Purpose To develop a fully automatic framework to detect COVID-19 using chest CT and evaluate its performances. Materials and Methods In this retrospective and multi-center study, a deep learning model, COVID-19 detection neural network (COVNet), was developed to extract visual features from volumetric chest CT exams for the detection of COVID-19. Community acquired pneumonia (CAP) and other non-pneumonia CT exams were included to test the robustness of the model. The datasets were collected from 6 hospitals between August 2016 and February 2020. Diagnostic performance was assessed by the area under the receiver operating characteristic curve (AUC), sensitivity and specificity. Results The collected dataset consisted of 4356 chest CT exams from 3,322 patients. The average age is 49±15 years and there were slightly more male patients than female (1838 vs 1484; p-value=0.29). The per-exam sensitivity and specificity for detecting COVID-19 in the independent test set was 114 of 127 (90% [95% CI: 83%, 94%]) and 294 of 307 (96% [95% CI: 93%, 98%]), respectively, with an AUC of 0.96 (p-value<0.001). The per-exam sensitivity and specificity for detecting CAP in the independent test set was 87% (152 of 175) and 92% (239 of 259), respectively, with an AUC of 0.95 (95% CI: 0.93, 0.97). Conclusions A deep learning model can accurately detect COVID-19 and differentiate it from community acquired pneumonia and other lung diseases.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Li</LastName>
<ForeName>Lin</ForeName>
<Initials>L</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0001-9903-8049</Identifier>
<AffiliationInfo><Affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Qin</LastName>
<ForeName>Lixin</ForeName>
<Initials>L</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0003-0966-3006</Identifier>
<AffiliationInfo><Affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Xu</LastName>
<ForeName>Zeguo</ForeName>
<Initials>Z</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0003-3610-0436</Identifier>
<AffiliationInfo><Affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Yin</LastName>
<ForeName>Youbing</ForeName>
<Initials>Y</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0001-9913-134X</Identifier>
<AffiliationInfo><Affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wang</LastName>
<ForeName>Xin</ForeName>
<Initials>X</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0002-7528-2407</Identifier>
<AffiliationInfo><Affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kong</LastName>
<ForeName>Bin</ForeName>
<Initials>B</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0003-2108-5341</Identifier>
<AffiliationInfo><Affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bai</LastName>
<ForeName>Junjie</ForeName>
<Initials>J</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0002-9134-1024</Identifier>
<AffiliationInfo><Affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lu</LastName>
<ForeName>Yi</ForeName>
<Initials>Y</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0002-6793-6212</Identifier>
<AffiliationInfo><Affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fang</LastName>
<ForeName>Zhenghan</ForeName>
<Initials>Z</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0002-2874-6619</Identifier>
<AffiliationInfo><Affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Song</LastName>
<ForeName>Qi</ForeName>
<Initials>Q</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0001-9805-1946</Identifier>
<AffiliationInfo><Affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Cao</LastName>
<ForeName>Kunlin</ForeName>
<Initials>K</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0003-2361-151X</Identifier>
<AffiliationInfo><Affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Liu</LastName>
<ForeName>Daliang</ForeName>
<Initials>D</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0002-3496-2174</Identifier>
<AffiliationInfo><Affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wang</LastName>
<ForeName>Guisheng</ForeName>
<Initials>G</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0002-5342-3870</Identifier>
<AffiliationInfo><Affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Xu</LastName>
<ForeName>Qizhong</ForeName>
<Initials>Q</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0001-7748-9586</Identifier>
<AffiliationInfo><Affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fang</LastName>
<ForeName>Xisheng</ForeName>
<Initials>X</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0003-3174-4267</Identifier>
<AffiliationInfo><Affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zhang</LastName>
<ForeName>Shiqin</ForeName>
<Initials>S</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0001-6677-1519</Identifier>
<AffiliationInfo><Affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Xia</LastName>
<ForeName>Juan</ForeName>
<Initials>J</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0002-9663-6577</Identifier>
<AffiliationInfo><Affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Xia</LastName>
<ForeName>Jun</ForeName>
<Initials>J</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0002-5689-0343</Identifier>
<AffiliationInfo><Affiliation>From the Department of Radiology, Wuhan Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L., Z. X., X. F., S. Z., J.X.), Jianghan University Affiliated Huangpi People's Hospital, Wuhan, Hubei, China 430301 (L. L.), Department of Radiology, Wuhan Pulmonary Hospital, Wuhan, Hubei, China 430030 (L. Q.), Keya Medical Technology Co., Ltd, Shenzhen, Guangdong, China 518116 (Y. Y., X. W., B. K., J. B., Y. L., Z. F, Q. S., K. C.), Department of Radiology, Liaocheng People's Hospital, Shandong, China, 252000 (D. L.), Department of CT, The Third Medical Center of Chinese PLA General Hospital, Beijing, China 100039 (G. W.), and Department of Radiology, Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China 518035 (Q. X., J. X.).</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2020</Year>
<Month>03</Month>
<Day>19</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Radiology</MedlineTA>
<NlmUniqueID>0401260</NlmUniqueID>
<ISSNLinking>0033-8419</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>AIM</CitationSubset>
<CitationSubset>IM</CitationSubset>
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<PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2020</Year>
<Month>3</Month>
<Day>20</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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<PubMedPubDate PubStatus="pubmed"><Year>2020</Year>
<Month>3</Month>
<Day>20</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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<PubMedPubDate PubStatus="medline"><Year>2020</Year>
<Month>3</Month>
<Day>20</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>aheadofprint</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">32191588</ArticleId>
<ArticleId IdType="doi">10.1148/radiol.2020200905</ArticleId>
</ArticleIdList>
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