[Clinical characteristics of 30 medical workers infected with new coronavirus pneumonia].
Identifieur interne : 000590 ( PubMed/Corpus ); précédent : 000589; suivant : 000591[Clinical characteristics of 30 medical workers infected with new coronavirus pneumonia].
Auteurs : M. Liu ; P. He ; H G Liu ; X J Wang ; F J Li ; S. Chen ; J. Lin ; P. Chen ; J H Liu ; C H LiSource :
- Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases [ 1001-0939 ] ; 2020.
English descriptors
- KwdEn :
- Adult, Betacoronavirus (pathogenicity), Body Mass Index, Coronavirus Infections (complications), Coronavirus Infections (diagnosis), Coronavirus Infections (transmission), Cough (etiology), Dyspnea (etiology), Female, Fever (classification), Fever (etiology), Fibrin Fibrinogen Degradation Products (analysis), Health Personnel, Humans, Infectious Disease Transmission, Patient-to-Professional, Leukocyte Count, Liver (pathology), Lymphocyte Count, Male, Middle Aged, Myocardium (pathology), Pneumonia, Viral (complications), Pneumonia, Viral (diagnosis), Pneumonia, Viral (transmission), Retrospective Studies, Risk Factors, Serum Albumin, Time Factors, Young Adult.
- MESH :
- chemical , analysis : Fibrin Fibrinogen Degradation Products.
- classification : Fever.
- complications : Coronavirus Infections, Pneumonia, Viral.
- diagnosis : Coronavirus Infections, Pneumonia, Viral.
- etiology : Cough, Dyspnea, Fever.
- pathogenicity : Betacoronavirus.
- pathology : Liver, Myocardium.
- transmission : Coronavirus Infections, Pneumonia, Viral.
- Adult, Body Mass Index, Female, Health Personnel, Humans, Infectious Disease Transmission, Patient-to-Professional, Leukocyte Count, Lymphocyte Count, Male, Middle Aged, Retrospective Studies, Risk Factors, Serum Albumin, Time Factors, Young Adult.
Abstract
Objective: To investigate the clinical characteristics of medical staff with novel coronavirus pneumonia(NCP). Methods: 30 patients infected with novel coronavirus referred to jianghan university hospital between January 11, 2020 and January 3, 2020 were studied. The data reviewed included those of clinical manifestations, laboratory investigation and Radiographic features. Results: The patients consisted of 10 men and 20 women, including 22 doctors and 8 nurses,aged 21~59 years(mean 35±8 years).They were divided to 26 common type and 4 severe cases, all of whom had close(within 1m) contact with patients infected of novel coronavirus pneumonia. The average contact times were 12 (7,16) and the average cumulative contact time was 2 (1.5,2.7) h.Clinical symptoms of these patients were fever in 23 patients (76.67%) , headache in 16 petients (53.33%) , fatigue or myalgia in 21patients (70%) , nausea, vomiting or diarrhea in 9 petients (30%) , cough in 25 petients (83.33%) , and dyspnea in 14 petients (46.67%) .Routine blood test revealed WBC<4.0×10(9)/L in 8 petients (26.67%) , (4-10) ×10(9)/L in 22 petients (73.33%) , and WBC>4.0×10(9)/L in 4 petients (13.33%) during the disease.Lymphocyte count<1.0×10(9)/L occurred in 12 petients (40%),abnormal liver function in 7 petients (23.33%) ,myocardial damage in 5 petients(16.67%), elevated D-dimer (>0.5mg/l) in 5 patients (16.67%). Compared with normal patients, the average exposure times, cumulative exposure time, BMI, Fever time, white blood cell count, liver enzyme, LDH, myoenzyme and D-dimer were significantly increased in severe patients, while the lymphocyte count and albumin levels in peripheral blood were significantly decreased.Chest CT mainly showed patchy shadows and interstitial changes.According to imaging examination, 11 patients (36.67%) showed Unilateral pneumonia and 19 patients (63.33%) showed bilateral pneumonia,4 patients (13.33%) showed bilateral multiple mottling and ground-glass opacity.Compared with the patients infected in the protected period, the proportion of severe infection and bilateral pneumonia were both increased in the patients infected in unprotected period. Conclusion: Medical staffs are at higher risk of infection.Infection rates are associated with contact time, the amount of suction virus. Severe patients had BMI increased, heating time prolonged, white blood cell count, lymphocyte count, D-dimer and albumin level significantly changed and were prone to be complicated with liver damage and myocardial damage.Strict protection measures is important to prevent infection for medical workers.
DOI: 10.3760/cma.j.issn.1001-0939.2020.03.014
PubMed: 32164090
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">[Clinical characteristics of 30 medical workers infected with new coronavirus pneumonia].</title><author><name sortKey="Liu, M" sort="Liu, M" uniqKey="Liu M" first="M" last="Liu">M. Liu</name><affiliation><nlm:affiliation>Department of Respiratory and Critical Care Medicine, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</nlm:affiliation></affiliation></author><author><name sortKey="He, P" sort="He, P" uniqKey="He P" first="P" last="He">P. He</name><affiliation><nlm:affiliation>Department of geriatrics, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</nlm:affiliation></affiliation></author><author><name sortKey="Liu, H G" sort="Liu, H G" uniqKey="Liu H" first="H G" last="Liu">H G Liu</name><affiliation><nlm:affiliation>Department of Respiratory and Critical Care Medicine, Tongji Hospital Affiliated to Tongji Medical College of HUST, Wuhan430030, China.</nlm:affiliation></affiliation></author><author><name sortKey="Wang, X J" sort="Wang, X J" uniqKey="Wang X" first="X J" last="Wang">X J Wang</name><affiliation><nlm:affiliation>Department of Respiratory and Critical Care Medicine, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</nlm:affiliation></affiliation></author><author><name sortKey="Li, F J" sort="Li, F J" uniqKey="Li F" first="F J" last="Li">F J Li</name><affiliation><nlm:affiliation>Department of Respiratory and Critical Care Medicine, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</nlm:affiliation></affiliation></author><author><name sortKey="Chen, S" sort="Chen, S" uniqKey="Chen S" first="S" last="Chen">S. Chen</name><affiliation><nlm:affiliation>Department of Respiratory and Critical Care Medicine, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</nlm:affiliation></affiliation></author><author><name sortKey="Lin, J" sort="Lin, J" uniqKey="Lin J" first="J" last="Lin">J. Lin</name><affiliation><nlm:affiliation>Department of generalization, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</nlm:affiliation></affiliation></author><author><name sortKey="Chen, P" sort="Chen, P" uniqKey="Chen P" first="P" last="Chen">P. Chen</name><affiliation><nlm:affiliation>Department of generalization, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</nlm:affiliation></affiliation></author><author><name sortKey="Liu, J H" sort="Liu, J H" uniqKey="Liu J" first="J H" last="Liu">J H Liu</name><affiliation><nlm:affiliation>Department of generalization, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</nlm:affiliation></affiliation></author><author><name sortKey="Li, C H" sort="Li, C H" uniqKey="Li C" first="C H" last="Li">C H Li</name><affiliation><nlm:affiliation>Department of Respiratory and Critical Care Medicine, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32164090</idno><idno type="pmid">32164090</idno><idno type="doi">10.3760/cma.j.issn.1001-0939.2020.03.014</idno><idno type="wicri:Area/PubMed/Corpus">000590</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000590</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">[Clinical characteristics of 30 medical workers infected with new coronavirus pneumonia].</title><author><name sortKey="Liu, M" sort="Liu, M" uniqKey="Liu M" first="M" last="Liu">M. Liu</name><affiliation><nlm:affiliation>Department of Respiratory and Critical Care Medicine, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</nlm:affiliation></affiliation></author><author><name sortKey="He, P" sort="He, P" uniqKey="He P" first="P" last="He">P. He</name><affiliation><nlm:affiliation>Department of geriatrics, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</nlm:affiliation></affiliation></author><author><name sortKey="Liu, H G" sort="Liu, H G" uniqKey="Liu H" first="H G" last="Liu">H G Liu</name><affiliation><nlm:affiliation>Department of Respiratory and Critical Care Medicine, Tongji Hospital Affiliated to Tongji Medical College of HUST, Wuhan430030, China.</nlm:affiliation></affiliation></author><author><name sortKey="Wang, X J" sort="Wang, X J" uniqKey="Wang X" first="X J" last="Wang">X J Wang</name><affiliation><nlm:affiliation>Department of Respiratory and Critical Care Medicine, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</nlm:affiliation></affiliation></author><author><name sortKey="Li, F J" sort="Li, F J" uniqKey="Li F" first="F J" last="Li">F J Li</name><affiliation><nlm:affiliation>Department of Respiratory and Critical Care Medicine, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</nlm:affiliation></affiliation></author><author><name sortKey="Chen, S" sort="Chen, S" uniqKey="Chen S" first="S" last="Chen">S. Chen</name><affiliation><nlm:affiliation>Department of Respiratory and Critical Care Medicine, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</nlm:affiliation></affiliation></author><author><name sortKey="Lin, J" sort="Lin, J" uniqKey="Lin J" first="J" last="Lin">J. Lin</name><affiliation><nlm:affiliation>Department of generalization, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</nlm:affiliation></affiliation></author><author><name sortKey="Chen, P" sort="Chen, P" uniqKey="Chen P" first="P" last="Chen">P. Chen</name><affiliation><nlm:affiliation>Department of generalization, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</nlm:affiliation></affiliation></author><author><name sortKey="Liu, J H" sort="Liu, J H" uniqKey="Liu J" first="J H" last="Liu">J H Liu</name><affiliation><nlm:affiliation>Department of generalization, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</nlm:affiliation></affiliation></author><author><name sortKey="Li, C H" sort="Li, C H" uniqKey="Li C" first="C H" last="Li">C H Li</name><affiliation><nlm:affiliation>Department of Respiratory and Critical Care Medicine, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases</title><idno type="ISSN">1001-0939</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Betacoronavirus (pathogenicity)</term><term>Body Mass Index</term><term>Coronavirus Infections (complications)</term><term>Coronavirus Infections (diagnosis)</term><term>Coronavirus Infections (transmission)</term><term>Cough (etiology)</term><term>Dyspnea (etiology)</term><term>Female</term><term>Fever (classification)</term><term>Fever (etiology)</term><term>Fibrin Fibrinogen Degradation Products (analysis)</term><term>Health Personnel</term><term>Humans</term><term>Infectious Disease Transmission, Patient-to-Professional</term><term>Leukocyte Count</term><term>Liver (pathology)</term><term>Lymphocyte Count</term><term>Male</term><term>Middle Aged</term><term>Myocardium (pathology)</term><term>Pneumonia, Viral (complications)</term><term>Pneumonia, Viral (diagnosis)</term><term>Pneumonia, Viral (transmission)</term><term>Retrospective Studies</term><term>Risk Factors</term><term>Serum Albumin</term><term>Time Factors</term><term>Young Adult</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Fibrin Fibrinogen Degradation Products</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Fever</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Cough</term><term>Dyspnea</term><term>Fever</term></keywords><keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Betacoronavirus</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Liver</term><term>Myocardium</term></keywords><keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Body Mass Index</term><term>Female</term><term>Health Personnel</term><term>Humans</term><term>Infectious Disease Transmission, Patient-to-Professional</term><term>Leukocyte Count</term><term>Lymphocyte Count</term><term>Male</term><term>Middle Aged</term><term>Retrospective Studies</term><term>Risk Factors</term><term>Serum Albumin</term><term>Time Factors</term><term>Young Adult</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><b>Objective:</b> To investigate the clinical characteristics of medical staff with novel coronavirus pneumonia(NCP). <b>Methods:</b> 30 patients infected with novel coronavirus referred to jianghan university hospital between January 11, 2020 and January 3, 2020 were studied. The data reviewed included those of clinical manifestations, laboratory investigation and Radiographic features. <b>Results:</b> The patients consisted of 10 men and 20 women, including 22 doctors and 8 nurses,aged 21~59 years(mean 35±8 years).They were divided to 26 common type and 4 severe cases, all of whom had close(within 1m) contact with patients infected of novel coronavirus pneumonia. The average contact times were 12 (7,16) and the average cumulative contact time was 2 (1.5,2.7) h.Clinical symptoms of these patients were fever in 23 patients (76.67%) , headache in 16 petients (53.33%) , fatigue or myalgia in 21patients (70%) , nausea, vomiting or diarrhea in 9 petients (30%) , cough in 25 petients (83.33%) , and dyspnea in 14 petients (46.67%) .Routine blood test revealed WBC<4.0×10(9)/L in 8 petients (26.67%) , (4-10) ×10(9)/L in 22 petients (73.33%) , and WBC>4.0×10(9)/L in 4 petients (13.33%) during the disease.Lymphocyte coun<i>t<</i>1.0×10(9)/L occurred in 12 petients (40%),abnormal liver function in 7 petients (23.33%) ,myocardial damage in 5 petients(16.67%), elevated D-dimer (>0.5mg/l) in 5 patients (16.67%). Compared with normal patients, the average exposure times, cumulative exposure time, BMI, Fever time, white blood cell count, liver enzyme, LDH, myoenzyme and D-dimer were significantly increased in severe patients, while the lymphocyte count and albumin levels in peripheral blood were significantly decreased.Chest CT mainly showed patchy shadows and interstitial changes.According to imaging examination, 11 patients (36.67%) showed Unilateral pneumonia and 19 patients (63.33%) showed bilateral pneumonia,4 patients (13.33%) showed bilateral multiple mottling and ground-glass opacity.Compared with the patients infected in the protected period, the proportion of severe infection and bilateral pneumonia were both increased in the patients infected in unprotected period. <b>Conclusion:</b> Medical staffs are at higher risk of infection.Infection rates are associated with contact time, the amount of suction virus. Severe patients had BMI increased, heating time prolonged, white blood cell count, lymphocyte count, D-dimer and albumin level significantly changed and were prone to be complicated with liver damage and myocardial damage.Strict protection measures is important to prevent infection for medical workers.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Curated" Owner="NLM"><PMID Version="1">32164090</PMID><DateCompleted><Year>2020</Year><Month>03</Month><Day>20</Day></DateCompleted><DateRevised><Year>2020</Year><Month>03</Month><Day>25</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">1001-0939</ISSN><JournalIssue CitedMedium="Print"><Volume>43</Volume><Issue>3</Issue><PubDate><Year>2020</Year><Month>Mar</Month><Day>12</Day></PubDate></JournalIssue><Title>Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases</Title><ISOAbbreviation>Zhonghua Jie He He Hu Xi Za Zhi</ISOAbbreviation></Journal><ArticleTitle>[Clinical characteristics of 30 medical workers infected with new coronavirus pneumonia].</ArticleTitle><Pagination><MedlinePgn>209-214</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.3760/cma.j.issn.1001-0939.2020.03.014</ELocationID><Abstract><AbstractText><b>Objective:</b> To investigate the clinical characteristics of medical staff with novel coronavirus pneumonia(NCP). <b>Methods:</b> 30 patients infected with novel coronavirus referred to jianghan university hospital between January 11, 2020 and January 3, 2020 were studied. The data reviewed included those of clinical manifestations, laboratory investigation and Radiographic features. <b>Results:</b> The patients consisted of 10 men and 20 women, including 22 doctors and 8 nurses,aged 21~59 years(mean 35±8 years).They were divided to 26 common type and 4 severe cases, all of whom had close(within 1m) contact with patients infected of novel coronavirus pneumonia. The average contact times were 12 (7,16) and the average cumulative contact time was 2 (1.5,2.7) h.Clinical symptoms of these patients were fever in 23 patients (76.67%) , headache in 16 petients (53.33%) , fatigue or myalgia in 21patients (70%) , nausea, vomiting or diarrhea in 9 petients (30%) , cough in 25 petients (83.33%) , and dyspnea in 14 petients (46.67%) .Routine blood test revealed WBC<4.0×10(9)/L in 8 petients (26.67%) , (4-10) ×10(9)/L in 22 petients (73.33%) , and WBC>4.0×10(9)/L in 4 petients (13.33%) during the disease.Lymphocyte coun<i>t<</i>1.0×10(9)/L occurred in 12 petients (40%),abnormal liver function in 7 petients (23.33%) ,myocardial damage in 5 petients(16.67%), elevated D-dimer (>0.5mg/l) in 5 patients (16.67%). Compared with normal patients, the average exposure times, cumulative exposure time, BMI, Fever time, white blood cell count, liver enzyme, LDH, myoenzyme and D-dimer were significantly increased in severe patients, while the lymphocyte count and albumin levels in peripheral blood were significantly decreased.Chest CT mainly showed patchy shadows and interstitial changes.According to imaging examination, 11 patients (36.67%) showed Unilateral pneumonia and 19 patients (63.33%) showed bilateral pneumonia,4 patients (13.33%) showed bilateral multiple mottling and ground-glass opacity.Compared with the patients infected in the protected period, the proportion of severe infection and bilateral pneumonia were both increased in the patients infected in unprotected period. <b>Conclusion:</b> Medical staffs are at higher risk of infection.Infection rates are associated with contact time, the amount of suction virus. Severe patients had BMI increased, heating time prolonged, white blood cell count, lymphocyte count, D-dimer and albumin level significantly changed and were prone to be complicated with liver damage and myocardial damage.Strict protection measures is important to prevent infection for medical workers.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Respiratory and Critical Care Medicine, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>He</LastName><ForeName>P</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of geriatrics, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>H G</ForeName><Initials>HG</Initials><AffiliationInfo><Affiliation>Department of Respiratory and Critical Care Medicine, Tongji Hospital Affiliated to Tongji Medical College of HUST, Wuhan430030, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>X J</ForeName><Initials>XJ</Initials><AffiliationInfo><Affiliation>Department of Respiratory and Critical Care Medicine, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>F J</ForeName><Initials>FJ</Initials><AffiliationInfo><Affiliation>Department of Respiratory and Critical Care Medicine, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>S</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Respiratory and Critical Care Medicine, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lin</LastName><ForeName>J</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of generalization, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>P</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of generalization, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>J H</ForeName><Initials>JH</Initials><AffiliationInfo><Affiliation>Department of generalization, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>C H</ForeName><Initials>CH</Initials><AffiliationInfo><Affiliation>Department of Respiratory and Critical Care Medicine, the Affiliated Hospital of Jianghan University, Wuhan430015, China.</Affiliation></AffiliationInfo></Author></AuthorList><Language>chi</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>China</Country><MedlineTA>Zhonghua Jie He He Hu Xi Za Zhi</MedlineTA><NlmUniqueID>8712226</NlmUniqueID><ISSNLinking>1001-0939</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D005338">Fibrin Fibrinogen Degradation Products</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D012709">Serum Albumin</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C036309">fibrin fragment D</NameOfSubstance></Chemical></ChemicalList><SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName><SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName></SupplMeshList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="N">Betacoronavirus</DescriptorName><QualifierName UI="Q000472" MajorTopicYN="Y">pathogenicity</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015992" MajorTopicYN="N">Body Mass Index</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="Y">Coronavirus Infections</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000635" MajorTopicYN="N">transmission</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003371" MajorTopicYN="N">Cough</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004417" MajorTopicYN="N">Dyspnea</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005334" MajorTopicYN="Y">Fever</DescriptorName><QualifierName UI="Q000145" MajorTopicYN="N">classification</QualifierName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005338" MajorTopicYN="N">Fibrin Fibrinogen Degradation Products</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006282" MajorTopicYN="Y">Health Personnel</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017758" MajorTopicYN="Y">Infectious Disease Transmission, Patient-to-Professional</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007958" MajorTopicYN="N">Leukocyte Count</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008099" MajorTopicYN="N">Liver</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018655" MajorTopicYN="N">Lymphocyte Count</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009206" MajorTopicYN="N">Myocardium</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011024" MajorTopicYN="Y">Pneumonia, Viral</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000635" MajorTopicYN="N">transmission</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012307" MajorTopicYN="N">Risk Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012709" MajorTopicYN="N">Serum Albumin</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList><OtherAbstract Type="Publisher" Language="chi"><AbstractText><b>目的：</b> 探讨医务人员新型冠状病毒肺炎（简称新冠肺炎）的临床特征。 <b>方法：</b> 对江汉大学附属医院2020年1月10—3l日收治的感染新冠肺炎的30例该院医务人员的临床表现、实验室、影像学资料进行分析。 <b>结果：</b> 30例医务人员感染者分别是医生22例, 护士8例；男10例，女20例，年龄21~59岁，平均（35±8）岁；普通型26例，重症4例，均有近距离（1m内）接触新冠肺炎患者的直接接触史，平均接触次数12（7，16）次，平均累计接触时间2（1.5，2.7）h。30例患者临床症状包括发热23例（76.67%），头痛16例（53.33%），乏力或全身酸痛21例（70%），恶心、呕吐或腹泻9例（30%），咳嗽25例（83.33%），呼吸困难14例（46.67%）。血白细胞（WBC）<4.0×10(9)/L者8例（26.67%），（4~10）×10(9)/L者22例（73.33%），病程中出现WBC>4.0×10(9)/L的患者4例（13.33%）；淋巴细胞计数<1.0×10(9)/L者12例（40%）；肝功能异常者7例（23.33%）；心肌受损者5例（16.67%），D-二聚体>0.5 mg/L者5例（16.67%）。与普通型患者相比，重症患者平均接触次数、累计接触时间、BMI值、平均热程、白细胞计数、肝酶、LDH、肌酶及D-二聚体显著升高，外周血淋巴细胞计数及白蛋白水平显著降低。胸部CT主要表现为多发小斑片影及间质改变，累及单肺者11例（36.67%），累及双肺者19例（63.33%），其中4例（13.33%）表现为典型的双肺弥漫性磨玻璃样改变。与防护期感染者相比，未防护期感染者重症比例增加，病灶累及双肺者增多。 <b>结论：</b> 医务人员具有感染新冠肺炎的高风险，感染几率与接触患者时间、吸入病毒量相关，重症患者的BMI增高、平均热程长、白细胞计数、淋巴细胞计数、D-二聚体、白蛋白水平明显改变，更易并发肝功能异常、心肌受损，加强防护是预防医务人员感染的重要措施。.</AbstractText></OtherAbstract><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Medical workers</Keyword><Keyword MajorTopicYN="N">Novel coronavirus</Keyword><Keyword MajorTopicYN="N">Pneumonia</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>3</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>3</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>3</Month><Day>21</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32164090</ArticleId><ArticleId IdType="doi">10.3760/cma.j.issn.1001-0939.2020.03.014</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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