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Epidemiological, clinical characteristics of cases of SARS-CoV-2 infection with abnormal imaging findings.

Identifieur interne : 000051 ( PubMed/Corpus ); précédent : 000050; suivant : 000052

Epidemiological, clinical characteristics of cases of SARS-CoV-2 infection with abnormal imaging findings.

Auteurs : Xiaoli Zhang ; Huan Cai ; Jianhua Hu ; Jiangshan Lian ; Jueqing Gu ; Shanyan Zhang ; Chanyuan Ye ; Yingfeng Lu ; Ciliang Jin ; Guodong Yu ; Hongyu Jia ; Yimin Zhang ; Jifang Sheng ; Lanjuan Li ; Yida Yang

Source :

RBID : pubmed:32205284

Abstract

To investigate the epidemiological, clinical characteristics of COVID-19 patients with abnormal imaging findings.

DOI: 10.1016/j.ijid.2020.03.040
PubMed: 32205284

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pubmed:32205284

Le document en format XML

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<nlm:affiliation>State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, No.79 QingChun Road, Hangzhou, Zhejiang, 310003, China.</nlm:affiliation>
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<name sortKey="Yang, Yida" sort="Yang, Yida" uniqKey="Yang Y" first="Yida" last="Yang">Yida Yang</name>
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<nlm:affiliation>State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, No.79 QingChun Road, Hangzhou, Zhejiang, 310003, China. Electronic address: yidayang65@zju.edu.cn.</nlm:affiliation>
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<title level="j">International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases</title>
<idno type="eISSN">1878-3511</idno>
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<date when="2020" type="published">2020</date>
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<div type="abstract" xml:lang="en">To investigate the epidemiological, clinical characteristics of COVID-19 patients with abnormal imaging findings.</div>
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<PMID Version="1">32205284</PMID>
<DateRevised>
<Year>2020</Year>
<Month>03</Month>
<Day>24</Day>
</DateRevised>
<Article PubModel="Print-Electronic">
<Journal>
<ISSN IssnType="Electronic">1878-3511</ISSN>
<JournalIssue CitedMedium="Internet">
<PubDate>
<Year>2020</Year>
<Month>Mar</Month>
<Day>20</Day>
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<Title>International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases</Title>
<ISOAbbreviation>Int. J. Infect. Dis.</ISOAbbreviation>
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<ArticleTitle>Epidemiological, clinical characteristics of cases of SARS-CoV-2 infection with abnormal imaging findings.</ArticleTitle>
<ELocationID EIdType="pii" ValidYN="Y">S1201-9712(20)30172-7</ELocationID>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.ijid.2020.03.040</ELocationID>
<Abstract>
<AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">To investigate the epidemiological, clinical characteristics of COVID-19 patients with abnormal imaging findings.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Patients confirmed with SARS-CoV-2 infection of Zhejiang province from Jan 17 to Feb 8 underwent CT or x-ray were enrolled. Epidemiological, clinical data were analyzed between those with abnormal or normal imaging findings.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Excluding 72 patients with normal images, 230 of 573 patients affected more than two lobes. The median radiograph score was 2.0 and there's negative correlation between the score and oxygenation index (ρ=-0.657,P < 0.001). Patients with abnormal images were older (46.65 ± 13.82), with higher rate of coexisting condition(28.8%), lower rate of exposure history and longer time between onset and confirmation(5d) than non-pneumonia patients(all P < 0.05). Higher rate of fever, cough, expectoration, and headache, lower lymphocytes, albumin, serum sodium levels and higher total bilirubin, creatine kinase, lactate dehydrogenase and C-reactive protein levels and lower oxygenation index were observed in pneumonia patients (all P < 0.05). Muscle ache, shortness of breath, nausea and vomiting, lower lymphocytes levels and higher serum creatinine and radiograph score at admission were predictive factors for severe/critical subtype.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Patients with abnormal images have more obvious clinical manifestations and laboratory changes. Combing clinical features and radiograph score can effectively predict severe/critical type.</AbstractText>
<CopyrightInformation>Copyright © 2020. Published by Elsevier Ltd.</CopyrightInformation>
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