Clinical Features of 69 Cases with Coronavirus Disease 2019 in Wuhan, China.
Identifieur interne : 000963 ( PubMed/Checkpoint ); précédent : 000962; suivant : 000964Clinical Features of 69 Cases with Coronavirus Disease 2019 in Wuhan, China.
Auteurs : Zhongliang Wang [République populaire de Chine] ; Bohan Yang [République populaire de Chine] ; Qianwen Li [République populaire de Chine] ; Lu Wen [République populaire de Chine] ; Ruiguang Zhang [République populaire de Chine]Source :
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [ 1537-6591 ] ; 2020.
Abstract
From December 2019 to February 2020, 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a serious outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China. Related clinical features are needed.
DOI: 10.1093/cid/ciaa272
PubMed: 32176772
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Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan</wicri:regionArea><placeName><settlement type="city">Wuhan</settlement><region type="région">Hubei</region></placeName></affiliation></author><author><name sortKey="Li, Qianwen" sort="Li, Qianwen" uniqKey="Li Q" first="Qianwen" last="Li">Qianwen Li</name><affiliation wicri:level="3"><nlm:affiliation>Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 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University of Science and Technology, Wuhan, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan</wicri:regionArea><placeName><settlement type="city">Wuhan</settlement><region type="région">Hubei</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32176772</idno><idno type="pmid">32176772</idno><idno type="doi">10.1093/cid/ciaa272</idno><idno type="wicri:Area/PubMed/Corpus">000448</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000448</idno><idno type="wicri:Area/PubMed/Curation">000448</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000448</idno><idno type="wicri:Area/PubMed/Checkpoint">000963</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000963</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Clinical Features of 69 Cases with Coronavirus Disease 2019 in Wuhan, China.</title><author><name sortKey="Wang, Zhongliang" sort="Wang, Zhongliang" uniqKey="Wang Z" first="Zhongliang" last="Wang">Zhongliang Wang</name><affiliation wicri:level="3"><nlm:affiliation>Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan</wicri:regionArea><placeName><settlement type="city">Wuhan</settlement><region type="région">Hubei</region></placeName></affiliation></author><author><name sortKey="Yang, Bohan" sort="Yang, Bohan" uniqKey="Yang B" first="Bohan" last="Yang">Bohan Yang</name><affiliation wicri:level="3"><nlm:affiliation>Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan</wicri:regionArea><placeName><settlement type="city">Wuhan</settlement><region type="région">Hubei</region></placeName></affiliation></author><author><name sortKey="Li, Qianwen" sort="Li, Qianwen" uniqKey="Li Q" first="Qianwen" last="Li">Qianwen Li</name><affiliation wicri:level="3"><nlm:affiliation>Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan</wicri:regionArea><placeName><settlement type="city">Wuhan</settlement><region type="région">Hubei</region></placeName></affiliation></author><author><name sortKey="Wen, Lu" sort="Wen, Lu" uniqKey="Wen L" first="Lu" last="Wen">Lu Wen</name><affiliation wicri:level="3"><nlm:affiliation>Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan</wicri:regionArea><placeName><settlement type="city">Wuhan</settlement><region type="région">Hubei</region></placeName></affiliation></author><author><name sortKey="Zhang, Ruiguang" sort="Zhang, Ruiguang" uniqKey="Zhang R" first="Ruiguang" last="Zhang">Ruiguang Zhang</name><affiliation wicri:level="3"><nlm:affiliation>Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan</wicri:regionArea><placeName><settlement type="city">Wuhan</settlement><region type="région">Hubei</region></placeName></affiliation></author></analytic><series><title level="j">Clinical infectious diseases : an official publication of the Infectious Diseases Society of America</title><idno type="eISSN">1537-6591</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">From December 2019 to February 2020, 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a serious outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China. Related clinical features are needed.</div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">32176772</PMID><DateRevised><Year>2020</Year><Month>03</Month><Day>16</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1537-6591</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2020</Year><Month>Mar</Month><Day>16</Day></PubDate></JournalIssue><Title>Clinical infectious diseases : an official publication of the Infectious Diseases Society of America</Title><ISOAbbreviation>Clin. Infect. Dis.</ISOAbbreviation></Journal><ArticleTitle>Clinical Features of 69 Cases with Coronavirus Disease 2019 in Wuhan, China.</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">ciaa272</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1093/cid/ciaa272</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">From December 2019 to February 2020, 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a serious outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China. Related clinical features are needed.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">We reviewed 69 patients who were hospitalized in Union hospital in Wuhan between January 16 to January 29, 2020. All patients were confirmed to be infected with SARS-CoV-2 and the final date of follow-up was February 4, 2020.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">The median age of 69 enrolled patients was 42.0 years (IQR 35.0-62.0), and 32 patients (46%) were men. The most common symptoms were fever (60[87%]), cough (38[55%]), and fatigue (29[42%]). Most patients received antiviral therapy (66 [98.5%] of 67 patients) and antibiotic therapy (66 [98.5%] of 67 patients). As of February 4, 2020, 18 (26.9%) of 67 patients had been discharged, and five patients had died, with a mortality rate of 7.5%. According to the lowest SpO2 during admission, cases were divided into the SpO2≥90% group (n=55) and the SpO2<90% group (n=14). All 5 deaths occurred in the SpO2<90% group. Compared with SpO2≥90% group, patients of the SpO2<90% group were older, and showed more comorbidities and higher plasma levels of IL6, IL10, lactate dehydrogenase, and c reactive protein. Arbidol treatment showed tendency to improve the discharging rate and decrease the mortality rate.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">COVID-19 appears to show frequent fever, dry cough, and increase of inflammatory cytokines, and induced a mortality rate of 7.5%. Older patients or those with underlying comorbidities are at higher risk of death.</AbstractText><CopyrightInformation>© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Zhongliang</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yang</LastName><ForeName>Bohan</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Qianwen</ForeName><Initials>Q</Initials><AffiliationInfo><Affiliation>Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wen</LastName><ForeName>Lu</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Ruiguang</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>03</Month><Day>16</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Clin Infect Dis</MedlineTA><NlmUniqueID>9203213</NlmUniqueID><ISSNLinking>1058-4838</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Wuhan</Keyword><Keyword MajorTopicYN="N">coronavirus</Keyword><Keyword MajorTopicYN="N">pneumonia</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>02</Month><Day>17</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>3</Month><Day>17</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>3</Month><Day>17</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>3</Month><Day>17</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32176772</ArticleId><ArticleId IdType="pii">5807944</ArticleId><ArticleId IdType="doi">10.1093/cid/ciaa272</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>République populaire de Chine</li></country><region><li>Hubei</li></region><settlement><li>Wuhan</li></settlement></list><tree><country name="République populaire de Chine"><region name="Hubei"><name sortKey="Wang, Zhongliang" sort="Wang, Zhongliang" uniqKey="Wang Z" first="Zhongliang" last="Wang">Zhongliang Wang</name></region><name sortKey="Li, Qianwen" sort="Li, Qianwen" uniqKey="Li Q" first="Qianwen" last="Li">Qianwen Li</name><name sortKey="Wen, Lu" sort="Wen, Lu" uniqKey="Wen L" first="Lu" last="Wen">Lu Wen</name><name sortKey="Yang, Bohan" sort="Yang, Bohan" uniqKey="Yang B" first="Bohan" last="Yang">Bohan Yang</name><name sortKey="Zhang, Ruiguang" sort="Zhang, Ruiguang" uniqKey="Zhang R" first="Ruiguang" last="Zhang">Ruiguang Zhang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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