Clinical characteristics and imaging manifestations of the 2019 novel coronavirus disease (COVID-19):A multi-center study in Wenzhou city, Zhejiang, China.
Identifieur interne : 000956 ( PubMed/Checkpoint ); précédent : 000955; suivant : 000957Clinical characteristics and imaging manifestations of the 2019 novel coronavirus disease (COVID-19):A multi-center study in Wenzhou city, Zhejiang, China.
Auteurs : Wenjie Yang [République populaire de Chine] ; Qiqi Cao [République populaire de Chine] ; Le Qin [République populaire de Chine] ; Xiaoyang Wang [République populaire de Chine] ; Zenghui Cheng [République populaire de Chine] ; Ashan Pan [République populaire de Chine] ; Jianyi Dai [République populaire de Chine] ; Qingfeng Sun [République populaire de Chine] ; Fengquan Zhao [République populaire de Chine] ; Jieming Qu [République populaire de Chine] ; Fuhua Yan [République populaire de Chine]Source :
- The Journal of infection [ 1532-2742 ] ; 2020.
Abstract
Little is known about COVID-19 outside Hubei. The aim of this paper was to describe the clinical characteristics and imaging manifestations of hospitalized patients with confirmed COVID-19 infection in Wenzhou, Zhejiang, China.
DOI: 10.1016/j.jinf.2020.02.016
PubMed: 32112884
Affiliations:
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Infectious Diseases, Wenzhou Central Hospital, Wenzhou 325000, Zhejiang province, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Wenzhou Central Hospital, Wenzhou 325000, Zhejiang province</wicri:regionArea><wicri:noRegion>Zhejiang province</wicri:noRegion></affiliation></author><author><name sortKey="Sun, Qingfeng" sort="Sun, Qingfeng" uniqKey="Sun Q" first="Qingfeng" last="Sun">Qingfeng Sun</name><affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Diseases, Ruian People's Hospital, Ruian 325200, Zhejiang province, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Ruian People's Hospital, Ruian 325200, Zhejiang province</wicri:regionArea><wicri:noRegion>Zhejiang province</wicri:noRegion></affiliation></author><author><name sortKey="Zhao, Fengquan" sort="Zhao, Fengquan" uniqKey="Zhao F" first="Fengquan" last="Zhao">Fengquan Zhao</name><affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Diseases, Wenzhou Central Hospital, Wenzhou 325000, Zhejiang province, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Wenzhou Central Hospital, Wenzhou 325000, Zhejiang province</wicri:regionArea><wicri:noRegion>Zhejiang province</wicri:noRegion></affiliation></author><author><name sortKey="Qu, Jieming" sort="Qu, Jieming" uniqKey="Qu J" first="Jieming" last="Qu">Jieming Qu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Respiratory and Critical Care Medicine, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, No.197 Ruijin Er Road, Shanghai 200025, China. Electronic address: jmqu0906@163.com.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Respiratory and Critical Care Medicine, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, No.197 Ruijin Er Road, Shanghai 200025</wicri:regionArea><wicri:noRegion>Shanghai 200025</wicri:noRegion></affiliation></author><author><name sortKey="Yan, Fuhua" sort="Yan, Fuhua" uniqKey="Yan F" first="Fuhua" last="Yan">Fuhua Yan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiology, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, No.197 Ruijin Er Road, Shanghai 200025, China. 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wicri:step="PubMed">000956</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Clinical characteristics and imaging manifestations of the 2019 novel coronavirus disease (COVID-19):A multi-center study in Wenzhou city, Zhejiang, China.</title><author><name sortKey="Yang, Wenjie" sort="Yang, Wenjie" uniqKey="Yang W" first="Wenjie" last="Yang">Wenjie Yang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiology, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, No.197 Ruijin Er Road, Shanghai 200025, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Radiology, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, No.197 Ruijin Er Road, Shanghai 200025</wicri:regionArea><wicri:noRegion>Shanghai 200025</wicri:noRegion></affiliation></author><author><name sortKey="Cao, Qiqi" sort="Cao, Qiqi" uniqKey="Cao Q" first="Qiqi" last="Cao">Qiqi Cao</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiology, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, No.197 Ruijin Er Road, Shanghai 200025, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Radiology, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, No.197 Ruijin Er Road, Shanghai 200025</wicri:regionArea><wicri:noRegion>Shanghai 200025</wicri:noRegion></affiliation></author><author><name sortKey="Qin, Le" sort="Qin, Le" uniqKey="Qin L" first="Le" last="Qin">Le Qin</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiology, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, No.197 Ruijin Er Road, Shanghai 200025, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Radiology, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, No.197 Ruijin Er Road, Shanghai 200025</wicri:regionArea><wicri:noRegion>Shanghai 200025</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Xiaoyang" sort="Wang, Xiaoyang" uniqKey="Wang X" first="Xiaoyang" last="Wang">Xiaoyang Wang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiology, Ruian People's Hospital, Ruian 325200, Zhejiang province, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Radiology, Ruian People's Hospital, Ruian 325200, Zhejiang province</wicri:regionArea><wicri:noRegion>Zhejiang province</wicri:noRegion></affiliation></author><author><name sortKey="Cheng, Zenghui" sort="Cheng, Zenghui" uniqKey="Cheng Z" first="Zenghui" last="Cheng">Zenghui Cheng</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiology, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, No.197 Ruijin Er Road, Shanghai 200025, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Radiology, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, No.197 Ruijin Er Road, Shanghai 200025</wicri:regionArea><wicri:noRegion>Shanghai 200025</wicri:noRegion></affiliation></author><author><name sortKey="Pan, Ashan" sort="Pan, Ashan" uniqKey="Pan A" first="Ashan" last="Pan">Ashan Pan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiology, Yueqing People's Hospital, Yueqing 325600, Zhejiang province, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Radiology, Yueqing People's Hospital, Yueqing 325600, Zhejiang province</wicri:regionArea><wicri:noRegion>Zhejiang province</wicri:noRegion></affiliation></author><author><name sortKey="Dai, Jianyi" sort="Dai, Jianyi" uniqKey="Dai J" first="Jianyi" last="Dai">Jianyi Dai</name><affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Diseases, Wenzhou Central Hospital, Wenzhou 325000, Zhejiang province, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Wenzhou Central Hospital, Wenzhou 325000, Zhejiang province</wicri:regionArea><wicri:noRegion>Zhejiang province</wicri:noRegion></affiliation></author><author><name sortKey="Sun, Qingfeng" sort="Sun, Qingfeng" uniqKey="Sun Q" first="Qingfeng" last="Sun">Qingfeng Sun</name><affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Diseases, Ruian People's Hospital, Ruian 325200, Zhejiang province, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Ruian People's Hospital, Ruian 325200, Zhejiang province</wicri:regionArea><wicri:noRegion>Zhejiang province</wicri:noRegion></affiliation></author><author><name sortKey="Zhao, Fengquan" sort="Zhao, Fengquan" uniqKey="Zhao F" first="Fengquan" last="Zhao">Fengquan Zhao</name><affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Diseases, Wenzhou Central Hospital, Wenzhou 325000, Zhejiang province, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Wenzhou Central Hospital, Wenzhou 325000, Zhejiang province</wicri:regionArea><wicri:noRegion>Zhejiang province</wicri:noRegion></affiliation></author><author><name sortKey="Qu, Jieming" sort="Qu, Jieming" uniqKey="Qu J" first="Jieming" last="Qu">Jieming Qu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Respiratory and Critical Care Medicine, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, No.197 Ruijin Er Road, Shanghai 200025, China. Electronic address: jmqu0906@163.com.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Respiratory and Critical Care Medicine, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, No.197 Ruijin Er Road, Shanghai 200025</wicri:regionArea><wicri:noRegion>Shanghai 200025</wicri:noRegion></affiliation></author><author><name sortKey="Yan, Fuhua" sort="Yan, Fuhua" uniqKey="Yan F" first="Fuhua" last="Yan">Fuhua Yan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiology, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, No.197 Ruijin Er Road, Shanghai 200025, China. Electronic address: yanfuhua@yahoo.com.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Radiology, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, No.197 Ruijin Er Road, Shanghai 200025</wicri:regionArea><wicri:noRegion>Shanghai 200025</wicri:noRegion></affiliation></author></analytic><series><title level="j">The Journal of infection</title><idno type="eISSN">1532-2742</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Little is known about COVID-19 outside Hubei. The aim of this paper was to describe the clinical characteristics and imaging manifestations of hospitalized patients with confirmed COVID-19 infection in Wenzhou, Zhejiang, China.</div></front></TEI><pubmed><MedlineCitation Status="In-Data-Review" Owner="NLM"><PMID Version="1">32112884</PMID><DateRevised><Year>2020</Year><Month>03</Month><Day>24</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1532-2742</ISSN><JournalIssue CitedMedium="Internet"><Volume>80</Volume><Issue>4</Issue><PubDate><Year>2020</Year><Month>Apr</Month></PubDate></JournalIssue><Title>The Journal of infection</Title><ISOAbbreviation>J. Infect.</ISOAbbreviation></Journal><ArticleTitle>Clinical characteristics and imaging manifestations of the 2019 novel coronavirus disease (COVID-19):A multi-center study in Wenzhou city, Zhejiang, China.</ArticleTitle><Pagination><MedlinePgn>388-393</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0163-4453(20)30099-2</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jinf.2020.02.016</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Little is known about COVID-19 outside Hubei. The aim of this paper was to describe the clinical characteristics and imaging manifestations of hospitalized patients with confirmed COVID-19 infection in Wenzhou, Zhejiang, China.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">In this retrospective cohort study, 149 RT-PCR confirmed positive patients were consecutively enrolled from January 17th to February 10th, 2020 in three tertiary hospitals of Wenzhou. Outcomes were followed up until Feb 15th, 2020.</AbstractText><AbstractText Label="FINDINGS" NlmCategory="RESULTS">A total of 85 patients had Hubei travel/residence history, while another 49 had contact with people from Hubei and 15 had no traceable exposure history to Hubei. Fever, cough and expectoration were the most common symptoms, 14 patients had decreased oxygen saturation, 33 had leukopenia, 53 had lymphopenia, and 82 had elevated C-reactive protein. On chest computed tomography (CT), lung segments 6 and 10 were mostly involved. A total of 287 segments presented ground glass opacity, 637 presented mixed opacity and 170 presented consolidation. Lesions were more localized in the peripheral lung with a patchy form. No significant difference was found between patients with or without Hubei exposure history. Seventeen patients had normal CT on admission of these, 12 had negative findings even10 days later.</AbstractText><AbstractText Label="INTERPRETATION" NlmCategory="CONCLUSIONS">Most patients presented with a mild infection in our study. The imaging pattern of multifocal peripheral ground glass or mixed opacity with predominance in the lower lung is highly suspicious of COVID-19 in the first week of disease onset. Nevetheless, some patients can present with a normal chest finding despite testing positive for COVID-19.</AbstractText><AbstractText Label="FUNDING" NlmCategory="BACKGROUND">We did not receive any fundings.</AbstractText><CopyrightInformation>Copyright © 2020. Published by Elsevier Ltd.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Yang</LastName><ForeName>Wenjie</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Department of Radiology, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, No.197 Ruijin Er Road, Shanghai 200025, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cao</LastName><ForeName>Qiqi</ForeName><Initials>Q</Initials><AffiliationInfo><Affiliation>Department of Radiology, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, No.197 Ruijin Er Road, Shanghai 200025, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Qin</LastName><ForeName>Le</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Radiology, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, No.197 Ruijin Er Road, Shanghai 200025, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Xiaoyang</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>Department of Radiology, Ruian People's Hospital, Ruian 325200, Zhejiang province, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cheng</LastName><ForeName>Zenghui</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>Department of Radiology, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, No.197 Ruijin Er Road, Shanghai 200025, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pan</LastName><ForeName>Ashan</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Radiology, Yueqing People's Hospital, Yueqing 325600, Zhejiang province, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dai</LastName><ForeName>Jianyi</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Infectious Diseases, Wenzhou Central Hospital, Wenzhou 325000, Zhejiang province, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sun</LastName><ForeName>Qingfeng</ForeName><Initials>Q</Initials><AffiliationInfo><Affiliation>Department of Infectious Diseases, Ruian People's Hospital, Ruian 325200, Zhejiang province, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhao</LastName><ForeName>Fengquan</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Department of Infectious Diseases, Wenzhou Central Hospital, Wenzhou 325000, Zhejiang province, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Qu</LastName><ForeName>Jieming</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Respiratory and Critical Care Medicine, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, No.197 Ruijin Er Road, Shanghai 200025, China. Electronic address: jmqu0906@163.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yan</LastName><ForeName>Fuhua</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Department of Radiology, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, No.197 Ruijin Er Road, Shanghai 200025, China. Electronic address: yanfuhua@yahoo.com.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>02</Month><Day>26</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J Infect</MedlineTA><NlmUniqueID>7908424</NlmUniqueID><ISSNLinking>0163-4453</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">COVID-19</Keyword><Keyword MajorTopicYN="N">CT</Keyword><Keyword MajorTopicYN="N">Infection</Keyword><Keyword MajorTopicYN="N">Lung</Keyword><Keyword MajorTopicYN="N">Outside Hubei</Keyword></KeywordList><CoiStatement>Declaration of Competing Interest The authors of this study declare that they each have no conflict of interest.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>02</Month><Day>20</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>02</Month><Day>21</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>3</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>3</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>3</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32112884</ArticleId><ArticleId IdType="pii">S0163-4453(20)30099-2</ArticleId><ArticleId IdType="doi">10.1016/j.jinf.2020.02.016</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Yang, Wenjie" sort="Yang, Wenjie" uniqKey="Yang W" first="Wenjie" last="Yang">Wenjie Yang</name></noRegion><name sortKey="Cao, Qiqi" sort="Cao, Qiqi" uniqKey="Cao Q" first="Qiqi" last="Cao">Qiqi Cao</name><name sortKey="Cheng, Zenghui" sort="Cheng, Zenghui" uniqKey="Cheng Z" first="Zenghui" last="Cheng">Zenghui Cheng</name><name sortKey="Dai, Jianyi" sort="Dai, Jianyi" uniqKey="Dai J" first="Jianyi" last="Dai">Jianyi Dai</name><name sortKey="Pan, Ashan" sort="Pan, Ashan" uniqKey="Pan A" first="Ashan" last="Pan">Ashan Pan</name><name sortKey="Qin, Le" sort="Qin, Le" uniqKey="Qin L" first="Le" last="Qin">Le Qin</name><name sortKey="Qu, Jieming" sort="Qu, Jieming" uniqKey="Qu J" first="Jieming" last="Qu">Jieming Qu</name><name sortKey="Sun, Qingfeng" sort="Sun, Qingfeng" uniqKey="Sun Q" first="Qingfeng" last="Sun">Qingfeng Sun</name><name sortKey="Wang, Xiaoyang" sort="Wang, Xiaoyang" uniqKey="Wang X" first="Xiaoyang" last="Wang">Xiaoyang Wang</name><name sortKey="Yan, Fuhua" sort="Yan, Fuhua" uniqKey="Yan F" first="Fuhua" last="Yan">Fuhua Yan</name><name sortKey="Zhao, Fengquan" sort="Zhao, Fengquan" uniqKey="Zhao F" first="Fengquan" last="Zhao">Fengquan Zhao</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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