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Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series.

Identifieur interne : 000935 ( PubMed/Checkpoint ); précédent : 000934; suivant : 000936

Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series.

Auteurs : Xiao-Wei Xu [République populaire de Chine] ; Xiao-Xin Wu [République populaire de Chine] ; Xian-Gao Jiang [République populaire de Chine] ; Kai-Jin Xu [République populaire de Chine] ; Ling-Jun Ying [République populaire de Chine] ; Chun-Lian Ma [République populaire de Chine] ; Shi-Bo Li [République populaire de Chine] ; Hua-Ying Wang [République populaire de Chine] ; Sheng Zhang [République populaire de Chine] ; Hai-Nv Gao [République populaire de Chine] ; Ji-Fang Sheng [République populaire de Chine] ; Hong-Liu Cai [République populaire de Chine] ; Yun-Qing Qiu [République populaire de Chine] ; Lan-Juan Li [République populaire de Chine]

Source :

RBID : pubmed:32075786

Descripteurs français

English descriptors

Abstract

To study the clinical characteristics of patients in Zhejiang province, China, infected with the 2019 severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) responsible for coronavirus disease 2019 (covid-2019).

DOI: 10.1136/bmj.m606
PubMed: 32075786


Affiliations:


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pubmed:32075786

Le document en format XML

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<div type="abstract" xml:lang="en">To study the clinical characteristics of patients in Zhejiang province, China, infected with the 2019 severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) responsible for coronavirus disease 2019 (covid-2019).</div>
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<Day>28</Day>
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<Day>28</Day>
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<Volume>368</Volume>
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<Year>2020</Year>
<Month>Feb</Month>
<Day>19</Day>
</PubDate>
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<ArticleTitle>Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series.</ArticleTitle>
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<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To study the clinical characteristics of patients in Zhejiang province, China, infected with the 2019 severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) responsible for coronavirus disease 2019 (covid-2019).</AbstractText>
<AbstractText Label="DESIGN" NlmCategory="METHODS">Retrospective case series.</AbstractText>
<AbstractText Label="SETTING" NlmCategory="METHODS">Seven hospitals in Zhejiang province, China.</AbstractText>
<AbstractText Label="PARTICIPANTS" NlmCategory="METHODS">62 patients admitted to hospital with laboratory confirmed SARS-Cov-2 infection. Data were collected from 10 January 2020 to 26 January 2020.</AbstractText>
<AbstractText Label="MAIN OUTCOME MEASURES" NlmCategory="METHODS">Clinical data, collected using a standardised case report form, such as temperature, history of exposure, incubation period. If information was not clear, the working group in Hangzhou contacted the doctor responsible for treating the patient for clarification.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Of the 62 patients studied (median age 41 years), only one was admitted to an intensive care unit, and no patients died during the study. According to research, none of the infected patients in Zhejiang province were ever exposed to the Huanan seafood market, the original source of the virus; all studied cases were infected by human to human transmission. The most common symptoms at onset of illness were fever in 48 (77%) patients, cough in 50 (81%), expectoration in 35 (56%), headache in 21 (34%), myalgia or fatigue in 32 (52%), diarrhoea in 3 (8%), and haemoptysis in 2 (3%). Only two patients (3%) developed shortness of breath on admission. The median time from exposure to onset of illness was 4 days (interquartile range 3-5 days), and from onset of symptoms to first hospital admission was 2 (1-4) days.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">As of early February 2020, compared with patients initially infected with SARS-Cov-2 in Wuhan, the symptoms of patients in Zhejiang province are relatively mild.</AbstractText>
<CopyrightInformation>Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.</CopyrightInformation>
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<LastName>Xu</LastName>
<ForeName>Xiao-Wei</ForeName>
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<Affiliation>Department of Infectious Disease, Wenzhou Central Hospital, Wenzhou, Zhejiang Province, China.</Affiliation>
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<LastName>Ying</LastName>
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<Affiliation>Department of Infectious Disease, Taizhou Enze Medical Centre (Group), Enze Hospital, Taizhou, Zhejiang Province, China.</Affiliation>
</AffiliationInfo>
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<ForeName>Chun-Lian</ForeName>
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<Affiliation>Department of Infectious Disease, First People's Hospital of Wenling, Wenling, Zhejiang Province, China.</Affiliation>
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<Affiliation>Department of Respiratory and Critical Care Medicine, Yinzhou People's Hospital, Affiliated Yinzhou Hospital, College of Medicine, Ningbo University, Ningbo City, Zhejiang Province, China.</Affiliation>
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<Affiliation>State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Centre for Infectious Diseases, Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, 310003, China ljli@zju.edu.cn.</Affiliation>
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<RefSource>BMJ. 2020 Feb 27;368:m792</RefSource>
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<RefSource>BMJ. 2020 Mar 20;368:m1113</RefSource>
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<CoiStatement>Competing interests: All authors have completed the ICMJE uniform disclosure form at www.icmje.org/coi_disclosure.pdf and declare: no support from any organisation for the submitted work; no financial relationships with any organisations that might have an interest in the submitted work in the previous three years; no other relationships or activities that could appear to have influenced the submitted work.</CoiStatement>
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<name sortKey="Qiu, Yun Qing" sort="Qiu, Yun Qing" uniqKey="Qiu Y" first="Yun-Qing" last="Qiu">Yun-Qing Qiu</name>
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