Chest computed tomography in children with COVID-19 respiratory infection
Identifieur interne : 000315 ( Pmc/Curation ); précédent : 000314; suivant : 000316Chest computed tomography in children with COVID-19 respiratory infection
Auteurs : Wei Li ; Huaqian Cui ; Kunwei Li ; Yijie Fang ; Shaolin LiSource :
- Pediatric Radiology [ 0301-0449 ] ; 2020.
Abstract
Infection with COVID-19 is currently rare in children.
To describe chest CT findings in children with COVID-19.
We studied children at a large tertiary-care hospital in China, during the period from 28 January 2019 to 8 February 2020, who had positive reverse transcriptase polymerase chain reaction (RT-PCR) for COVID-19. We recorded findings at any chest CT performed in the included children, along with core clinical observations.
We included five children from 10 months to 6 years of age (mean 3.4 years). All had had at least one CT scan after admission. Three of these five had CT abnormality on the first CT scan (at 2 days, 4 days and 9 days, respectively, after onset of symptoms) in the form of patchy ground-glass opacities; all normalised during treatment.
Compared to reports in adults, we found similar but more modest lung abnormalities at CT in our small paediatric cohort.
Url:
DOI: 10.1007/s00247-020-04656-7
PubMed: 31901986
PubMed Central: 7080075
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Wei Li<affiliation><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.12981.33</institution-id><institution-id institution-id-type="ISNI">0000 0001 2360 039X</institution-id><institution>Guangdong Provincial Key Laboratory of Biomedical Imaging, Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University,</institution></institution-wrap>52 East Meihua Road, New Xiangzhou, Zhuhai, Guangdong Province China</nlm:aff><wicri:noCountry code="subfield">Guangdong Province China</wicri:noCountry></affiliation><affiliation><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="GRID">grid.12981.33</institution-id><institution-id institution-id-type="ISNI">0000 0001 2360 039X</institution-id><institution>Department of Medical Affairs, The Fifth Affiliated Hospital,</institution><institution>Sun Yat-sen University,</institution></institution-wrap>52 East Meihua Road, New Xiangzhou, Zhuhai, Guangdong Province China</nlm:aff><wicri:noCountry code="subfield">Guangdong Province China</wicri:noCountry></affiliation><affiliation><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.12981.33</institution-id><institution-id institution-id-type="ISNI">0000 0001 2360 039X</institution-id><institution>Guangdong Provincial Key Laboratory of Biomedical Imaging, Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University,</institution></institution-wrap>52 East Meihua Road, New Xiangzhou, Zhuhai, Guangdong Province China</nlm:aff><wicri:noCountry code="subfield">Guangdong Province China</wicri:noCountry></affiliation><affiliation><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.12981.33</institution-id><institution-id institution-id-type="ISNI">0000 0001 2360 039X</institution-id><institution>Guangdong Provincial Key Laboratory of Biomedical Imaging, Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University,</institution></institution-wrap>52 East Meihua Road, New Xiangzhou, Zhuhai, Guangdong Province China</nlm:aff><wicri:noCountry code="subfield">Guangdong Province China</wicri:noCountry></affiliation><affiliation><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.12981.33</institution-id><institution-id institution-id-type="ISNI">0000 0001 2360 039X</institution-id><institution>Guangdong Provincial Key Laboratory of Biomedical Imaging, Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University,</institution></institution-wrap>52 East Meihua Road, New Xiangzhou, Zhuhai, Guangdong Province China</nlm:aff><wicri:noCountry code="subfield">Guangdong Province China</wicri:noCountry></affiliation>Le document en format XML
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xml:lang="en"><sec><title>Background</title><p id="Par1">Infection with COVID-19 is currently rare in children.</p></sec><sec><title>Objective</title><p id="Par2">To describe chest CT findings in children with COVID-19.</p></sec><sec><title>Materials and methods</title><p id="Par3">We studied children at a large tertiary-care hospital in China, during the period from 28 January 2019 to 8 February 2020, who had positive reverse transcriptase polymerase chain reaction (RT-PCR) for COVID-19. We recorded findings at any chest CT performed in the included children, along with core clinical observations.</p></sec><sec><title>Results</title><p id="Par4">We included five children from 10 months to 6 years of age (mean 3.4 years). All had had at least one CT scan after admission. Three of these five had CT abnormality on the first CT scan (at 2 days, 4 days and 9 days, respectively, after onset of symptoms) in the form of patchy ground-glass opacities; all normalised during treatment.</p></sec><sec><title>Conclusion</title><p id="Par5">Compared to reports in adults, we found similar but more modest lung abnormalities at CT in our small paediatric cohort.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Pediatr Radiol</journal-id><journal-id journal-id-type="iso-abbrev">Pediatr Radiol</journal-id><journal-title-group><journal-title>Pediatric Radiology</journal-title></journal-title-group><issn pub-type="ppub">0301-0449</issn><issn pub-type="epub">1432-1998</issn><publisher><publisher-name>Springer Berlin Heidelberg</publisher-name><publisher-loc>Berlin/Heidelberg</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">31901986</article-id><article-id pub-id-type="pmc">7080075</article-id><article-id pub-id-type="publisher-id">4656</article-id><article-id pub-id-type="doi">10.1007/s00247-020-04656-7</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject></subj-group></article-categories><title-group><article-title>Chest computed tomography in children with COVID-19 respiratory infection</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Li</surname><given-names>Wei</given-names></name><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Cui</surname><given-names>Huaqian</given-names></name><xref ref-type="aff" rid="Aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Li</surname><given-names>Kunwei</given-names></name><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Fang</surname><given-names>Yijie</given-names></name><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Li</surname><given-names>Shaolin</given-names></name><address><email>lishlin5@mail.sysu.edu.cn</email></address><xref ref-type="aff" rid="Aff1">1</xref></contrib><aff id="Aff1"><label>1</label><institution-wrap><institution-id institution-id-type="GRID">grid.12981.33</institution-id><institution-id institution-id-type="ISNI">0000 0001 2360 039X</institution-id><institution>Guangdong Provincial Key Laboratory of Biomedical Imaging, Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University,</institution></institution-wrap>52 East Meihua Road, New Xiangzhou, Zhuhai, Guangdong Province China</aff><aff id="Aff2"><label>2</label><institution-wrap><institution-id institution-id-type="GRID">grid.12981.33</institution-id><institution-id institution-id-type="ISNI">0000 0001 2360 039X</institution-id><institution>Department of Medical Affairs, The Fifth Affiliated Hospital,</institution><institution>Sun Yat-sen University,</institution></institution-wrap>52 East Meihua Road, New Xiangzhou, Zhuhai, Guangdong Province China</aff></contrib-group><pub-date pub-type="epub"><day>11</day><month>3</month><year>2020</year></pub-date><fpage>1</fpage><lpage>4</lpage><history><date date-type="received"><day>18</day><month>2</month><year>2020</year></date><date date-type="rev-recd"><day>18</day><month>2</month><year>2020</year></date><date date-type="accepted"><day>2</day><month>3</month><year>2020</year></date></history><permissions><copyright-statement>© Springer-Verlag GmbH Germany, part of Springer Nature 2020</copyright-statement><license><license-p>This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.</license-p></license></permissions><abstract id="Abs1"><sec><title>Background</title><p id="Par1">Infection with COVID-19 is currently rare in children.</p></sec><sec><title>Objective</title><p id="Par2">To describe chest CT findings in children with COVID-19.</p></sec><sec><title>Materials and methods</title><p id="Par3">We studied children at a large tertiary-care hospital in China, during the period from 28 January 2019 to 8 February 2020, who had positive reverse transcriptase polymerase chain reaction (RT-PCR) for COVID-19. We recorded findings at any chest CT performed in the included children, along with core clinical observations.</p></sec><sec><title>Results</title><p id="Par4">We included five children from 10 months to 6 years of age (mean 3.4 years). All had had at least one CT scan after admission. Three of these five had CT abnormality on the first CT scan (at 2 days, 4 days and 9 days, respectively, after onset of symptoms) in the form of patchy ground-glass opacities; all normalised during treatment.</p></sec><sec><title>Conclusion</title><p id="Par5">Compared to reports in adults, we found similar but more modest lung abnormalities at CT in our small paediatric cohort.</p></sec></abstract><kwd-group xml:lang="en"><title>Keywords</title><kwd>Child</kwd><kwd>Computed tomography</kwd><kwd>Coronavirus</kwd><kwd>COVID-19</kwd><kwd>Pneumonia</kwd><kwd>Viral</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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