SARS-CoV-2 and COVID-19: The most important research questions
Identifieur interne : 000231 ( Pmc/Curation ); précédent : 000230; suivant : 000232SARS-CoV-2 and COVID-19: The most important research questions
Auteurs : Kit-San Yuen [Hong Kong] ; Zi Wei Ye [Hong Kong] ; Sin-Yee Fung [Hong Kong] ; Chi-Ping Chan [Hong Kong] ; Dong-Yan Jin [Hong Kong]Source :
- Cell & Bioscience [ 2045-3701 ] ; 2020.
Abstract
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing global health emergency. Here we highlight nine most important research questions concerning virus transmission, asymptomatic and presymptomatic virus shedding, diagnosis, treatment, vaccine development, origin of virus and viral pathogenesis.
Url:
DOI: 10.1186/s13578-020-00404-4
PubMed: 32190290
PubMed Central: 7074995
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PMC:7074995Le document en format XML
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sortKey="Ye, Zi Wei" sort="Ye, Zi Wei" uniqKey="Ye Z" first="Zi Wei" last="Ye">Zi Wei Ye</name><affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="GRID">grid.194645.b</institution-id><institution-id institution-id-type="ISNI">0000000121742757</institution-id><institution>Department of Microbiology,</institution><institution>The University of Hong Kong,</institution></institution-wrap>Pokfulam, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Pokfulam</wicri:regionArea></affiliation></author><author><name sortKey="Fung, Sin Yee" sort="Fung, Sin Yee" uniqKey="Fung S" first="Sin-Yee" last="Fung">Sin-Yee Fung</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.194645.b</institution-id><institution-id institution-id-type="ISNI">0000000121742757</institution-id><institution>School of Biomedical Sciences,</institution><institution>The University 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sort="Jin, Dong Yan" uniqKey="Jin D" first="Dong-Yan" last="Jin">Dong-Yan Jin</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.194645.b</institution-id><institution-id institution-id-type="ISNI">0000000121742757</institution-id><institution>School of Biomedical Sciences,</institution><institution>The University of Hong Kong,</institution></institution-wrap>3/F Laboratory Block, 21 Sassoon Road, Pokfulam, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>3/F Laboratory Block, 21 Sassoon Road, Pokfulam</wicri:regionArea></affiliation></author></analytic><series><title level="j">Cell & Bioscience</title><idno type="eISSN">2045-3701</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="Par1">Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing global health emergency. 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Cell Biosci</journal-id><journal-id journal-id-type="iso-abbrev">Cell Biosci</journal-id><journal-title-group><journal-title>Cell & Bioscience</journal-title></journal-title-group><issn pub-type="epub">2045-3701</issn><publisher><publisher-name>BioMed Central</publisher-name><publisher-loc>London</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">32190290</article-id><article-id pub-id-type="pmc">7074995</article-id><article-id pub-id-type="publisher-id">404</article-id><article-id pub-id-type="doi">10.1186/s13578-020-00404-4</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Highlight</subject></subj-group></article-categories><title-group><article-title>SARS-CoV-2 and COVID-19: The most important research questions</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Yuen</surname><given-names>Kit-San</given-names></name><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Ye</surname><given-names>Zi -Wei</given-names></name><xref ref-type="aff" rid="Aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Fung</surname><given-names>Sin-Yee</given-names></name><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Chan</surname><given-names>Chi-Ping</given-names></name><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2778-3530</contrib-id><name><surname>Jin</surname><given-names>Dong-Yan</given-names></name><address><email>dyjin@hku.hk</email></address><xref ref-type="aff" rid="Aff1">1</xref></contrib><aff id="Aff1"><label>1</label><institution-wrap><institution-id institution-id-type="GRID">grid.194645.b</institution-id><institution-id institution-id-type="ISNI">0000000121742757</institution-id><institution>School of Biomedical Sciences,</institution><institution>The University of Hong Kong,</institution></institution-wrap>3/F Laboratory Block, 21 Sassoon Road, Pokfulam, Hong Kong</aff><aff id="Aff2"><label>2</label><institution-wrap><institution-id institution-id-type="GRID">grid.194645.b</institution-id><institution-id institution-id-type="ISNI">0000000121742757</institution-id><institution>Department of Microbiology,</institution><institution>The University of Hong Kong,</institution></institution-wrap>Pokfulam, Hong Kong</aff></contrib-group><pub-date pub-type="epub"><day>16</day><month>3</month><year>2020</year></pub-date><pub-date pub-type="pmc-release"><day>16</day><month>3</month><year>2020</year></pub-date><pub-date pub-type="collection"><year>2020</year></pub-date><volume>10</volume><elocation-id>40</elocation-id><history><date date-type="received"><day>26</day><month>2</month><year>2020</year></date><date date-type="accepted"><day>7</day><month>3</month><year>2020</year></date></history><permissions><copyright-statement>© The Author(s) 2020</copyright-statement><license license-type="OpenAccess"><license-p><bold>Open Access</bold>This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">http://creativecommons.org/licenses/by/4.0/</ext-link>. The Creative Commons Public Domain Dedication waiver (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/publicdomain/zero/1.0/">http://creativecommons.org/publicdomain/zero/1.0/</ext-link>) applies to the data made available in this article, unless otherwise stated in a credit line to the data.</license-p></license></permissions><abstract id="Abs1"><p id="Par1">Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing global health emergency. Here we highlight nine most important research questions concerning virus transmission, asymptomatic and presymptomatic virus shedding, diagnosis, treatment, vaccine development, origin of virus and viral pathogenesis.</p></abstract><kwd-group xml:lang="en"><title>Keywords</title><kwd>SARS-CoV-2</kwd><kwd>COVID-19</kwd><kwd>2019 novel coronavirus (2019-nCoV)</kwd><kwd>Novel coronavirus pneumonia (NCP)</kwd></kwd-group><funding-group><award-group><funding-source><institution>Health and Medical Resaerch Fund</institution></funding-source><award-id>HKM-15-M01</award-id><principal-award-recipient><name><surname>Jin</surname><given-names>Dong-Yan</given-names></name></principal-award-recipient></award-group></funding-group><funding-group><award-group><funding-source><institution-wrap><institution-id institution-id-type="FundRef">http://dx.doi.org/10.13039/501100002920</institution-id><institution>Research Grants Council, University Grants Committee</institution></institution-wrap></funding-source><award-id>T11-707/15-R</award-id><principal-award-recipient><name><surname>Jin</surname><given-names>Dong-Yan</given-names></name></principal-award-recipient></award-group></funding-group><custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name><meta-value>© The Author(s) 2020</meta-value></custom-meta></custom-meta-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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