Links to Exploration step
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Mice with human immune system components as in vivo models for infections with human pathogens</title><author><name sortKey="R Mer, Patrick C" sort="R Mer, Patrick C" uniqKey="R Mer P" first="Patrick C." last="R Mer">Patrick C. R Mer</name></author><author><name sortKey="Chijioke, Obinna" sort="Chijioke, Obinna" uniqKey="Chijioke O" first="Obinna" last="Chijioke">Obinna Chijioke</name></author><author><name sortKey="Meixlsperger, Sonja" sort="Meixlsperger, Sonja" uniqKey="Meixlsperger S" first="Sonja" last="Meixlsperger">Sonja Meixlsperger</name></author><author><name sortKey="Leung, Carol S" sort="Leung, Carol S" uniqKey="Leung C" first="Carol S." last="Leung">Carol S. Leung</name></author><author><name sortKey="Munz, Christian" sort="Munz, Christian" uniqKey="Munz C" first="Christian" last="Münz">Christian Münz</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">21301484</idno><idno type="pmc">3087174</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087174</idno><idno type="RBID">PMC:3087174</idno><idno type="doi">10.1038/icb.2010.151</idno><date when="2011">2011</date><idno type="wicri:Area/Pmc/Corpus">000653</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000653</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Mice with human immune system components as in vivo models for infections with human pathogens</title><author><name sortKey="R Mer, Patrick C" sort="R Mer, Patrick C" uniqKey="R Mer P" first="Patrick C." last="R Mer">Patrick C. R Mer</name></author><author><name sortKey="Chijioke, Obinna" sort="Chijioke, Obinna" uniqKey="Chijioke O" first="Obinna" last="Chijioke">Obinna Chijioke</name></author><author><name sortKey="Meixlsperger, Sonja" sort="Meixlsperger, Sonja" uniqKey="Meixlsperger S" first="Sonja" last="Meixlsperger">Sonja Meixlsperger</name></author><author><name sortKey="Leung, Carol S" sort="Leung, Carol S" uniqKey="Leung C" first="Carol S." last="Leung">Carol S. Leung</name></author><author><name sortKey="Munz, Christian" sort="Munz, Christian" uniqKey="Munz C" first="Christian" last="Münz">Christian Münz</name></author></analytic><series><title level="j">Immunology and cell biology</title><idno type="ISSN">0818-9641</idno><idno type="eISSN">1440-1711</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Many pathogens relevant to human disease do not infect other animal species. Therefore, animal models that reconstitute or harbour human tissues are explored as hosts for these. In this review, we will summarize recent advances to utilize mice with human immune system components, reconstituted from hematopoietic progenitor cells in vivo. Such mice can be used to study human pathogens that replicate in leucocytes. In addition to studying the replication of these pathogens, the reconstituted human immune system components can also be analyzed for initiating immune responses and control against these infections. Moreover, these new animal models of human infectious disease should replicate the reactivity of the human immune system to vaccine candidates and, especially, the adjuvants contained in them, more faithfully.</p></div></front></TEI><pmc article-type="research-article" xml:lang="en"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">8706300</journal-id><journal-id journal-id-type="pubmed-jr-id">4179</journal-id><journal-id journal-id-type="nlm-ta">Immunol Cell Biol</journal-id><journal-title-group><journal-title>Immunology and cell biology</journal-title></journal-title-group><issn pub-type="ppub">0818-9641</issn><issn pub-type="epub">1440-1711</issn></journal-meta><article-meta><article-id pub-id-type="pmid">21301484</article-id><article-id pub-id-type="pmc">3087174</article-id><article-id pub-id-type="doi">10.1038/icb.2010.151</article-id><article-id pub-id-type="manuscript">NIHMS292058</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Mice with human immune system components as in vivo models for infections with human pathogens</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Rämer</surname><given-names>Patrick C.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Chijioke</surname><given-names>Obinna</given-names></name></contrib><contrib contrib-type="author"><name><surname>Meixlsperger</surname><given-names>Sonja</given-names></name></contrib><contrib contrib-type="author"><name><surname>Leung</surname><given-names>Carol S.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Münz</surname><given-names>Christian</given-names></name></contrib><aff id="A1">Viral Immunobiology, Institute of Experimental Immunology, University of Zürich, CH-8057 Zürich, Switzerland</aff></contrib-group><author-notes><corresp id="CR1"><label>*</label>Address correspondence to: Christian Münz, Viral Immunobiology, Institute of Experimental Immunology, University Hospital Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland, Tel.: +41-44-635-3716, Fax: +41-44-635-6883, <email>christian.muenz@usz.ch</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>27</day><month>4</month><year>2011</year></pub-date><pub-date pub-type="epub"><day>8</day><month>2</month><year>2011</year></pub-date><pub-date pub-type="ppub"><month>3</month><year>2011</year></pub-date><pub-date pub-type="pmc-release"><day>1</day><month>3</month><year>2012</year></pub-date><volume>89</volume><issue>3</issue><fpage>408</fpage><lpage>416</lpage><abstract><p id="P1">Many pathogens relevant to human disease do not infect other animal species. Therefore, animal models that reconstitute or harbour human tissues are explored as hosts for these. In this review, we will summarize recent advances to utilize mice with human immune system components, reconstituted from hematopoietic progenitor cells in vivo. Such mice can be used to study human pathogens that replicate in leucocytes. In addition to studying the replication of these pathogens, the reconstituted human immune system components can also be analyzed for initiating immune responses and control against these infections. Moreover, these new animal models of human infectious disease should replicate the reactivity of the human immune system to vaccine candidates and, especially, the adjuvants contained in them, more faithfully.</p></abstract><kwd-group><kwd>Epstein Barr virus</kwd><kwd>HIV</kwd><kwd>Dengue virus</kwd><kwd>natural killer cells</kwd><kwd>T cells</kwd><kwd>myeloid cells</kwd><kwd>human vaccination</kwd></kwd-group><funding-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>R01 CA108609-08 || CA</award-id></award-group></funding-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV2/Data/Pmc/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000653 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 000653 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= CovidV2
|flux= Pmc
|étape= Corpus
|type= RBID
|clé=
|texte=
}}
| This area was generated with Dilib version V0.6.33. |  |