Antigenic relationships amongst coronaviruses
Identifieur interne : 000173 ( Pmc/Corpus ); précédent : 000172; suivant : 000174Antigenic relationships amongst coronaviruses
Auteurs : A. F. BradburneSource :
- Archiv Fur Die Gesamte Virusforschung [ 0003-9012 ] ; 1970.
Abstract
Several serological interrelationships between various members of the corona-virus group have been revealed in neutralization, complement fixation, and gel-diffusion tests, using human and hyperimmune animal sera. Several members of this group of human and animal pathogens are shown to cross-react in one or more type of test, but one member, avian infectious bronchitis virus, was shown to be unrelated. Mouse hepatitis virus (MHV3) was found to be antigenically related to a number of human types of coronavirus. Difficulties were encountered in the investigation of paired human sera in demonstrating the specificity of antibody rises, placing doubt on the values of some serological studies. The significance of these interrelationships is discussed in the light of other investigations.
Url:
DOI: 10.1007/BF01253769
PubMed: 4321451
PubMed Central: 7086994
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Antigenic relationships amongst coronaviruses</title><author><name sortKey="Bradburne, A F" sort="Bradburne, A F" uniqKey="Bradburne A" first="A. F." last="Bradburne">A. F. Bradburne</name><affiliation><nlm:aff id="Aff1">Present Address: Common Cold Unit, Harvard Hospital, Coombe Road, Salisbury, Wiltshire England</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">4321451</idno><idno type="pmc">7086994</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086994</idno><idno type="RBID">PMC:7086994</idno><idno type="doi">10.1007/BF01253769</idno><date when="1970">1970</date><idno type="wicri:Area/Pmc/Corpus">000173</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000173</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Antigenic relationships amongst coronaviruses</title><author><name sortKey="Bradburne, A F" sort="Bradburne, A F" uniqKey="Bradburne A" first="A. F." last="Bradburne">A. F. Bradburne</name><affiliation><nlm:aff id="Aff1">Present Address: Common Cold Unit, Harvard Hospital, Coombe Road, Salisbury, Wiltshire England</nlm:aff></affiliation></author></analytic><series><title level="j">Archiv Fur Die Gesamte Virusforschung</title><idno type="ISSN">0003-9012</idno><idno type="eISSN">1432-8798</idno><imprint><date when="1970">1970</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Summary</title><p>Several serological interrelationships between various members of the corona-virus group have been revealed in neutralization, complement fixation, and gel-diffusion tests, using human and hyperimmune animal sera. Several members of this group of human and animal pathogens are shown to cross-react in one or more type of test, but one member, avian infectious bronchitis virus, was shown to be unrelated. Mouse hepatitis virus (MHV<sub>3</sub>) was found to be antigenically related to a number of human types of coronavirus. Difficulties were encountered in the investigation of paired human sera in demonstrating the specificity of antibody rises, placing doubt on the values of some serological studies. The significance of these interrelationships is discussed in the light of other investigations.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Becker, W B" uniqKey="Becker W">W. B. Becker</name></author><author><name sortKey="Mcintosh, K" uniqKey="Mcintosh K">K. McIntosh</name></author><author><name sortKey="Dees, J H" uniqKey="Dees J">J. H. Dees</name></author><author><name sortKey="Chanock, R M" uniqKey="Chanock R">R. M. Chanock</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Berry, D M" uniqKey="Berry D">D. M. Berry</name></author><author><name sortKey="Almeida, June D" uniqKey="Almeida J">June D. Almeida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Berrt, D M" uniqKey="Berrt D">D. M. Berrt</name></author><author><name sortKey="Cruickshank, J G" uniqKey="Cruickshank J">J. G. Cruickshank</name></author><author><name sortKey="Chu, H P" uniqKey="Chu H">H. P. Chu</name></author><author><name sortKey="Wells, R J H" uniqKey="Wells R">R. J. H. Wells</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bradburne, A F" uniqKey="Bradburne A">A. F. Bradburne</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bradburne, A F" uniqKey="Bradburne A">A. F. Bradburne</name></author><author><name sortKey="Tyrrell, D A J" uniqKey="Tyrrell D">D. A. J. Tyrrell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Davis, E V" uniqKey="Davis E">E. V. 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Arch Gesamte Virusforsch</journal-id><journal-id journal-id-type="iso-abbrev">Arch Gesamte Virusforsch</journal-id><journal-title-group><journal-title>Archiv Fur Die Gesamte Virusforschung</journal-title></journal-title-group><issn pub-type="ppub">0003-9012</issn><issn pub-type="epub">1432-8798</issn><publisher><publisher-name>Springer-Verlag</publisher-name><publisher-loc>Vienna</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">4321451</article-id><article-id pub-id-type="pmc">7086994</article-id><article-id pub-id-type="publisher-id">BF01253769</article-id><article-id pub-id-type="doi">10.1007/BF01253769</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Antigenic relationships amongst coronaviruses</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Bradburne</surname><given-names>A. F.</given-names></name><xref ref-type="aff" rid="Aff1"></xref></contrib><aff id="Aff1">Present Address: Common Cold Unit, Harvard Hospital, Coombe Road, Salisbury, Wiltshire England</aff></contrib-group><pub-date pub-type="ppub"><year>1970</year></pub-date><volume>31</volume><issue>3</issue><fpage>352</fpage><lpage>364</lpage><history><date date-type="received"><day>6</day><month>2</month><year>1970</year></date></history><permissions><copyright-statement>© Springer-Verlag 1970</copyright-statement><license><license-p>This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.</license-p></license></permissions><abstract id="Abs1"><title>Summary</title><p>Several serological interrelationships between various members of the corona-virus group have been revealed in neutralization, complement fixation, and gel-diffusion tests, using human and hyperimmune animal sera. Several members of this group of human and animal pathogens are shown to cross-react in one or more type of test, but one member, avian infectious bronchitis virus, was shown to be unrelated. Mouse hepatitis virus (MHV<sub>3</sub>) was found to be antigenically related to a number of human types of coronavirus. Difficulties were encountered in the investigation of paired human sera in demonstrating the specificity of antibody rises, placing doubt on the values of some serological studies. 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