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New porcine epidemic diarrhoea virus variant with a large deletion in the spike gene identified in domestic pigs

Identifieur interne : 000542 ( Pmc/Checkpoint ); précédent : 000541; suivant : 000543

New porcine epidemic diarrhoea virus variant with a large deletion in the spike gene identified in domestic pigs

Auteurs : Tsuneyuki Masuda ; Satoshi Murakami [Japon] ; Osamu Takahashi [Japon] ; Ayako Miyazaki ; Seiichi Ohashi ; Hiroshi Yamasato ; Tohru Suzuki

Source :

RBID : PMC:7087250

Abstract

From October 2013 to date, approximately 1,000 outbreaks of porcine epidemic diarrhoea virus (PEDV) have occurred in Japan. Porcine epidemic diarrhoea with non-lethal effects in piglets was identified in Tottori prefecture in October 2014. Complete genome analysis revealed that the causative pathogen, Tottori2, is a new PEDV variant with a large (582 nt) deletion in the spike gene. Phylogenetic analysis indicated that the Tottori2 PEDV strain might have been derived from the current PEDV strains circulating in domestic pigs. Moreover, the Tottori2 PEDV strain was successfully isolated in Vero cells by serial passage.

Electronic supplementary material

The online version of this article (doi:10.1007/s00705-015-2522-z) contains supplementary material, which is available to authorized users.


Url:
DOI: 10.1007/s00705-015-2522-z
PubMed: 26162305
PubMed Central: 7087250


Affiliations:


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PMC:7087250

Le document en format XML

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<subj-group subj-group-type="heading">
<subject>Brief Report</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>New porcine epidemic diarrhoea virus variant with a large deletion in the spike gene identified in domestic pigs</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Masuda</surname>
<given-names>Tsuneyuki</given-names>
</name>
<xref ref-type="aff" rid="Aff1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Murakami</surname>
<given-names>Satoshi</given-names>
</name>
<xref ref-type="aff" rid="Aff2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Takahashi</surname>
<given-names>Osamu</given-names>
</name>
<xref ref-type="aff" rid="Aff2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Miyazaki</surname>
<given-names>Ayako</given-names>
</name>
<xref ref-type="aff" rid="Aff3">3</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Ohashi</surname>
<given-names>Seiichi</given-names>
</name>
<xref ref-type="aff" rid="Aff3">3</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Yamasato</surname>
<given-names>Hiroshi</given-names>
</name>
<xref ref-type="aff" rid="Aff1">1</xref>
</contrib>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Suzuki</surname>
<given-names>Tohru</given-names>
</name>
<address>
<phone>81-29-838-7841</phone>
<email>t_suzuki@affrc.go.jp</email>
</address>
<xref ref-type="aff" rid="Aff3">3</xref>
</contrib>
<aff id="Aff1">
<label>1</label>
Kurayoshi Livestock Hygiene Service Center, Kurayoshi, Tottori Japan</aff>
<aff id="Aff2">
<label>2</label>
Life Technologies Japan Ltd., Thermo Fisher Scientific, Tokyo, Japan</aff>
<aff id="Aff3">
<label>3</label>
<institution-wrap>
<institution-id institution-id-type="GRID">grid.416882.1</institution-id>
<institution-id institution-id-type="ISNI">0000000405309488</institution-id>
<institution>Viral Disease and Epidemiology Research Division,</institution>
<institution>National Institute of Animal Health, National Agriculture and Food Research Organization,</institution>
</institution-wrap>
3-1-5 Kannondai, Tsukuba, Ibaraki 305-0856 Japan</aff>
</contrib-group>
<pub-date pub-type="epub">
<day>11</day>
<month>7</month>
<year>2015</year>
</pub-date>
<pub-date pub-type="ppub">
<year>2015</year>
</pub-date>
<volume>160</volume>
<issue>10</issue>
<fpage>2565</fpage>
<lpage>2568</lpage>
<history>
<date date-type="received">
<day>1</day>
<month>4</month>
<year>2015</year>
</date>
<date date-type="accepted">
<day>1</day>
<month>7</month>
<year>2015</year>
</date>
</history>
<permissions>
<copyright-statement>© Springer-Verlag Wien 2015</copyright-statement>
<license>
<license-p>This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.</license-p>
</license>
</permissions>
<abstract id="Abs1">
<p id="Par1">From October 2013 to date, approximately 1,000 outbreaks of porcine epidemic diarrhoea virus (PEDV) have occurred in Japan. Porcine epidemic diarrhoea with non-lethal effects in piglets was identified in Tottori prefecture in October 2014. Complete genome analysis revealed that the causative pathogen, Tottori2, is a new PEDV variant with a large (582 nt) deletion in the spike gene. Phylogenetic analysis indicated that the Tottori2 PEDV strain might have been derived from the current PEDV strains circulating in domestic pigs. Moreover, the Tottori2 PEDV strain was successfully isolated in Vero cells by serial passage.</p>
<sec>
<title>Electronic supplementary material</title>
<p>The online version of this article (doi:10.1007/s00705-015-2522-z) contains supplementary material, which is available to authorized users.</p>
</sec>
</abstract>
<kwd-group xml:lang="en">
<title>Keywords</title>
<kwd>Vero Cell</kwd>
<kwd>Porcine Epidemic Diarrhoea Virus</kwd>
<kwd>Porcine Epidemic Diarrhoea Virus Strain</kwd>
<kwd>Tottori Prefecture</kwd>
<kwd>Porcine Epidemic Diarrhoea Virus Isolate</kwd>
</kwd-group>
<custom-meta-group>
<custom-meta>
<meta-name>issue-copyright-statement</meta-name>
<meta-value>© Springer-Verlag Wien 2015</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
</pmc>
<affiliations>
<list>
<country>
<li>Japon</li>
</country>
<region>
<li>Région de Kantō</li>
</region>
<settlement>
<li>Tokyo</li>
</settlement>
</list>
<tree>
<noCountry>
<name sortKey="Masuda, Tsuneyuki" sort="Masuda, Tsuneyuki" uniqKey="Masuda T" first="Tsuneyuki" last="Masuda">Tsuneyuki Masuda</name>
<name sortKey="Miyazaki, Ayako" sort="Miyazaki, Ayako" uniqKey="Miyazaki A" first="Ayako" last="Miyazaki">Ayako Miyazaki</name>
<name sortKey="Ohashi, Seiichi" sort="Ohashi, Seiichi" uniqKey="Ohashi S" first="Seiichi" last="Ohashi">Seiichi Ohashi</name>
<name sortKey="Suzuki, Tohru" sort="Suzuki, Tohru" uniqKey="Suzuki T" first="Tohru" last="Suzuki">Tohru Suzuki</name>
<name sortKey="Yamasato, Hiroshi" sort="Yamasato, Hiroshi" uniqKey="Yamasato H" first="Hiroshi" last="Yamasato">Hiroshi Yamasato</name>
</noCountry>
<country name="Japon">
<region name="Région de Kantō">
<name sortKey="Murakami, Satoshi" sort="Murakami, Satoshi" uniqKey="Murakami S" first="Satoshi" last="Murakami">Satoshi Murakami</name>
</region>
<name sortKey="Takahashi, Osamu" sort="Takahashi, Osamu" uniqKey="Takahashi O" first="Osamu" last="Takahashi">Osamu Takahashi</name>
</country>
</tree>
</affiliations>
</record>

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