Synthesis and Antiviral Activity of Several N-Containing 5α-STEROIDS
Identifieur interne : 000446 ( Pmc/Checkpoint ); précédent : 000445; suivant : 000447Synthesis and Antiviral Activity of Several N-Containing 5α-STEROIDS
Auteurs : N. Sh. Nadaraia [Géorgie (pays)] ; E. O. Onashvili [Géorgie (pays)] ; M. L. Kakhabrishvili [Géorgie (pays)] ; N. N. Barbakadze [Géorgie (pays)] ; B. Sylla ; A. PichetteSource :
- Chemistry of Natural Compounds [ 0009-3130 ] ; 2016.
Abstract
A study of the antiviral activity of several new hydrazones and amines and amides of 5α-steroids that were synthesized by us earlier found highly and moderately active compounds. The structures of the synthesized compounds were proven using IR, PMR, 13C NMR, and mass spectral data.
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DOI: 10.1007/s10600-016-1795-0
PubMed: NONE
PubMed Central: 7088190
Affiliations:
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Sh." last="Nadaraia">N. Sh. Nadaraia</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.412274.6</institution-id><institution-id institution-id-type="ISNI">0000000404288304</institution-id><institution>I. Kutateladze Institute of Pharmaceutical Chemistry,</institution><institution>Tbilisi State Medical University,</institution></institution-wrap>Tbilisi, 0159 Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Tbilisi</wicri:regionArea></affiliation></author><author><name sortKey="Onashvili, E O" sort="Onashvili, E O" uniqKey="Onashvili E" first="E. O." last="Onashvili">E. O. Onashvili</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.412274.6</institution-id><institution-id institution-id-type="ISNI">0000000404288304</institution-id><institution>I. 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Pichette</name><affiliation><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="GRID">grid.265695.b</institution-id><institution>LASEVE, Universite Quebec a Chicoutim,</institution></institution-wrap>Chicoutimi, QC Canada G7H 2BI</nlm:aff><wicri:noCountry code="subfield">QC Canada G7H 2BI</wicri:noCountry></affiliation></author></analytic><series><title level="j">Chemistry of Natural Compounds</title><idno type="ISSN">0009-3130</idno><idno type="eISSN">1573-8388</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="Par1">A study of the antiviral activity of several new hydrazones and amines and amides of 5α-steroids that were synthesized by us earlier found highly and moderately active compounds. The structures of the synthesized compounds were proven using IR, PMR, <sup>13</sup>C NMR, and mass spectral data.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Banday, Ah" uniqKey="Banday A">AH Banday</name></author><author><name sortKey="Shameem, Sa" uniqKey="Shameem S">SA Shameem</name></author><author><name sortKey="Jeelani, S" uniqKey="Jeelani S">S Jeelani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Deive, N" uniqKey="Deive N">N Deive</name></author><author><name sortKey="Rodriguez, J" uniqKey="Rodriguez J">J Rodriguez</name></author><author><name sortKey="Jimenez, C" uniqKey="Jimenez C">C Jimenez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Choudhary, Mi" uniqKey="Choudhary M">MI Choudhary</name></author><author><name sortKey="Alam, Ms" uniqKey="Alam M">MS Alam</name></author><author><name sortKey="Rahman, A" uniqKey="Rahman A">A 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uniqKey="Kakhabrishvili M">ML Kakhabrishvili</name></author><author><name sortKey="Barbakadze, Nn" uniqKey="Barbakadze N">NN Barbakadze</name></author><author><name sortKey="Mulkidzhanyan, Kg" uniqKey="Mulkidzhanyan K">KG Mulkidzhanyan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sikharulidze, Mi" uniqKey="Sikharulidze M">MI Sikharulidze</name></author><author><name sortKey="Nadaraia, Ns" uniqKey="Nadaraia N">NS Nadaraia</name></author><author><name sortKey="Kakhabrishvili, Ml" uniqKey="Kakhabrishvili M">ML Kakhabrishvili</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Merlani, Mi" uniqKey="Merlani M">MI Merlani</name></author><author><name sortKey="Davitishvili, Mg" uniqKey="Davitishvili M">MG Davitishvili</name></author><author><name sortKey="Nadaraia, Ns" uniqKey="Nadaraia N">NS Nadaraia</name></author><author><name sortKey="Sikharulidze, Mi" uniqKey="Sikharulidze M">MI 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Sikharulidze</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Men Hova, Ni" uniqKey="Men Hova N">NI Men′shova</name></author><author><name sortKey="Korzinkina, Na" uniqKey="Korzinkina N">NA Korzinkina</name></author><author><name sortKey="Kemertelidze, Ep" uniqKey="Kemertelidze E">EP Kemertelidze</name></author><author><name sortKey="Nadaraia, Ns" uniqKey="Nadaraia N">NS Nadaraia</name></author><author><name sortKey="Davitishvili, Mg" uniqKey="Davitishvili M">MG Davitishvili</name></author><author><name sortKey="Lishcheta, Li" uniqKey="Lishcheta L">LI Lishcheta</name></author><author><name sortKey="Grosheva, Vs" uniqKey="Grosheva V">VS Grosheva</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Chem Nat Compd</journal-id><journal-id journal-id-type="iso-abbrev">Chem Nat Compd</journal-id><journal-title-group><journal-title>Chemistry of Natural Compounds</journal-title></journal-title-group><issn pub-type="ppub">0009-3130</issn><issn pub-type="epub">1573-8388</issn><publisher><publisher-name>Springer US</publisher-name><publisher-loc>New York</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmc">7088190</article-id><article-id pub-id-type="publisher-id">1795</article-id><article-id pub-id-type="doi">10.1007/s10600-016-1795-0</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Synthesis and Antiviral Activity of Several <italic>N</italic>-Containing 5<italic>α</italic>-STEROIDS</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Nadaraia</surname><given-names>N. Sh.</given-names></name><address><fax>(99532) 52 00 23</fax><email>nnadaraia@ymail.com</email></address><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Onashvili</surname><given-names>E. O.</given-names></name><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Kakhabrishvili</surname><given-names>M. L.</given-names></name><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Barbakadze</surname><given-names>N. N.</given-names></name><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Sylla</surname><given-names>B.</given-names></name><xref ref-type="aff" rid="Aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Pichette</surname><given-names>A.</given-names></name><address><fax>(1) 418 545 50 12</fax><email>andre_pichette@uqac.ca</email></address><xref ref-type="aff" rid="Aff2">2</xref></contrib><aff id="Aff1"><label>1</label><institution-wrap><institution-id institution-id-type="GRID">grid.412274.6</institution-id><institution-id institution-id-type="ISNI">0000000404288304</institution-id><institution>I. Kutateladze Institute of Pharmaceutical Chemistry,</institution><institution>Tbilisi State Medical University,</institution></institution-wrap>Tbilisi, 0159 Georgia</aff><aff id="Aff2"><label>2</label><institution-wrap><institution-id institution-id-type="GRID">grid.265695.b</institution-id><institution>LASEVE, Universite Quebec a Chicoutim,</institution></institution-wrap>Chicoutimi, QC Canada G7H 2BI</aff></contrib-group><pub-date pub-type="epub"><day>11</day><month>8</month><year>2016</year></pub-date><pub-date pub-type="ppub"><year>2016</year></pub-date><volume>52</volume><issue>5</issue><fpage>853</fpage><lpage>855</lpage><history><date date-type="received"><day>21</day><month>1</month><year>2016</year></date></history><permissions><copyright-statement>© Springer Science+Business Media New York 2016</copyright-statement><license><license-p>This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.</license-p></license></permissions><abstract id="Abs1"><p id="Par1">A study of the antiviral activity of several new hydrazones and amines and amides of 5α-steroids that were synthesized by us earlier found highly and moderately active compounds. The structures of the synthesized compounds were proven using IR, PMR, <sup>13</sup>C NMR, and mass spectral data.</p></abstract><kwd-group xml:lang="en"><title>Keywords</title><kwd>5<italic>α</italic>-steroids</kwd><kwd>synthesis</kwd><kwd>hydrazides</kwd><kwd>hydrazones</kwd><kwd>amines</kwd><kwd>amides</kwd><kwd>antiviral activity</kwd></kwd-group><custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name><meta-value>© Springer Science+Business Media New York 2016</meta-value></custom-meta></custom-meta-group></article-meta></front></pmc><affiliations><list><country><li>Géorgie (pays)</li></country></list><tree><noCountry><name sortKey="Pichette, A" sort="Pichette, A" uniqKey="Pichette A" first="A." last="Pichette">A. Pichette</name><name sortKey="Sylla, B" sort="Sylla, B" uniqKey="Sylla B" first="B." last="Sylla">B. Sylla</name></noCountry><country name="Géorgie (pays)"><noRegion><name sortKey="Nadaraia, N Sh" sort="Nadaraia, N Sh" uniqKey="Nadaraia N" first="N. Sh." last="Nadaraia">N. Sh. Nadaraia</name></noRegion><name sortKey="Barbakadze, N N" sort="Barbakadze, N N" uniqKey="Barbakadze N" first="N. N." last="Barbakadze">N. N. Barbakadze</name><name sortKey="Kakhabrishvili, M L" sort="Kakhabrishvili, M L" uniqKey="Kakhabrishvili M" first="M. L." last="Kakhabrishvili">M. L. Kakhabrishvili</name><name sortKey="Onashvili, E O" sort="Onashvili, E O" uniqKey="Onashvili E" first="E. O." last="Onashvili">E. O. Onashvili</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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