Spontaneous intracranial hemorrhage in a patient with Middle East respiratory syndrome corona virus
Identifieur interne : 000365 ( Pmc/Checkpoint ); précédent : 000364; suivant : 000366Spontaneous intracranial hemorrhage in a patient with Middle East respiratory syndrome corona virus
Auteurs : Fahad M. Al-HameedSource :
- Saudi Medical Journal [ 0379-5284 ] ; 2017.
Abstract
The Middle East respiratory syndrome corona virus (MERS-CoV) is a novel positive sense singlestranded ribonucleic acid virus of the genus Beta corona virus. This virus was first isolated from a patient who died from severe respiratory illness in June 2012 in Jeddah, Kingdom of Saudi Arabia. We describe an unusual case of a 42 year old healthcare worker who was admitted to our Intensive Care Unit (ICU) King Abdul-Aziz Medical City, with MERS-CoV and severe acute respiratory distress Syndrome and developed a sudden-onset diabetes insipidus and spontaneous massive intracranial hemorrhage with intra-ventricular extension and tonsillar herniation. Computed angiogram of the brain did not reveal any aneurysm or structural defects. She never had uncontrolled hypertension, or coagulopathy, nor she received antiplatelets. We are reporting a rare case of structural neurological damage associated with MERS-CoV infection.
Url:
DOI: 10.15537/smj.2017.2.16255
PubMed: 28133694
PubMed Central: 5329633
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We describe an unusual case of a 42 year old healthcare worker who was admitted to our Intensive Care Unit (ICU) King Abdul-Aziz Medical City, with MERS-CoV and severe acute respiratory distress Syndrome and developed a sudden-onset diabetes insipidus and spontaneous massive intracranial hemorrhage with intra-ventricular extension and tonsillar herniation. Computed angiogram of the brain did not reveal any aneurysm or structural defects. She never had uncontrolled hypertension, or coagulopathy, nor she received antiplatelets. 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Saudi Med J</journal-id><journal-id journal-id-type="iso-abbrev">Saudi Med J</journal-id><journal-title-group><journal-title>Saudi Medical Journal</journal-title></journal-title-group><issn pub-type="ppub">0379-5284</issn><publisher><publisher-name>Saudi Medical Journal</publisher-name><publisher-loc>Saudi Arabia</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">28133694</article-id><article-id pub-id-type="pmc">5329633</article-id><article-id pub-id-type="publisher-id">SaudiMedJ-38-196</article-id><article-id pub-id-type="doi">10.15537/smj.2017.2.16255</article-id><article-categories><subj-group subj-group-type="heading"><subject>Case Report</subject></subj-group></article-categories><title-group><article-title>Spontaneous intracranial hemorrhage in a patient with Middle East respiratory syndrome corona virus</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Al-Hameed</surname><given-names>Fahad M.</given-names></name><degrees>MD, FRCPC</degrees><xref ref-type="aff" rid="aff1"></xref><xref ref-type="corresp" rid="cor1"></xref></contrib></contrib-group><aff id="aff1"><italic>From the Department of Intensive Care, College of Medicine, King Saud bin Abdul-Aziz University for Health Sciences, King Abdul-Aziz Medical City, National Guard Health Affairs, Jeddah, Kingdom of Saudi Arabia</italic></aff><author-notes><corresp id="cor1"><italic>Address correspondence and reprint request to: Dr. Fahad Al-Hameed, Department of Intensive Care, College of Medicine, King Saud bin Abdul-Aziz University for Health Sciences, King Abdul-Aziz Medical City, National Guard Health Affairs, Jeddah, Kingdom of Saudi Arabia. E-mail: <email xlink:href="fahadalhameed@hotmail.com">fahadalhameed@hotmail.com</email> ORCID: <ext-link ext-link-type="uri" xlink:href="http://orcid.org/0000-0003-0231-871X">http://orcid.org/0000-0003-0231-871X</ext-link></italic></corresp></author-notes><pub-date pub-type="ppub"><month>2</month><year>2017</year></pub-date><volume>38</volume><issue>2</issue><fpage>196</fpage><lpage>200</lpage><history><date date-type="received"><day>06</day><month>9</month><year>2016</year></date><date date-type="accepted"><day>02</day><month>11</month><year>2016</year></date></history><permissions><copyright-statement>Copyright: © Saudi Medical Journal</copyright-statement><copyright-year>2017</copyright-year><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-sa/3.0"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><abstract><p>The Middle East respiratory syndrome corona virus (MERS-CoV) is a novel positive sense singlestranded ribonucleic acid virus of the genus Beta corona virus. This virus was first isolated from a patient who died from severe respiratory illness in June 2012 in Jeddah, Kingdom of Saudi Arabia. We describe an unusual case of a 42 year old healthcare worker who was admitted to our Intensive Care Unit (ICU) King Abdul-Aziz Medical City, with MERS-CoV and severe acute respiratory distress Syndrome and developed a sudden-onset diabetes insipidus and spontaneous massive intracranial hemorrhage with intra-ventricular extension and tonsillar herniation. Computed angiogram of the brain did not reveal any aneurysm or structural defects. She never had uncontrolled hypertension, or coagulopathy, nor she received antiplatelets. We are reporting a rare case of structural neurological damage associated with MERS-CoV infection.</p></abstract></article-meta></front></pmc><affiliations><list></list><tree><noCountry><name sortKey="Al Hameed, Fahad M" sort="Al Hameed, Fahad M" uniqKey="Al Hameed F" first="Fahad M." last="Al-Hameed">Fahad M. Al-Hameed</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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