Fecal specimen diagnosis 2019 novel coronavirus-infected pneumonia.
Identifieur interne : 000C98 ( Ncbi/Merge ); précédent : 000C97; suivant : 000C99Fecal specimen diagnosis 2019 novel coronavirus-infected pneumonia.
Auteurs : Jingcheng Zhang [République populaire de Chine] ; Saibin Wang [République populaire de Chine] ; Yadong Xue [République populaire de Chine]Source :
- Journal of medical virology [ 1096-9071 ] ; 2020.
Abstract
The emergence and spread of 2019 novel coronavirus-infected pneumonia (COVID-19) from Wuhan, China, it has spread globally. We extracted the data on 14 patients with laboratory-confirmed COVID-19 from Jinhua Municipal Central hospital through 27 January 2020. We found that compared to pharyngeal swab specimens, nucleic acid detection of COVID-19 in fecal specimens was equally accurate. And we found that patients with a positive stool test did not experience gastrointestinal symptoms and had nothing to do with the severity of the lung infection. These results may help to understand the clinical diagnosis and the changes in clinical parameters of COVID-19.
DOI: 10.1002/jmv.25742
PubMed: 32124995
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<front><div type="abstract" xml:lang="en">The emergence and spread of 2019 novel coronavirus-infected pneumonia (COVID-19) from Wuhan, China, it has spread globally. We extracted the data on 14 patients with laboratory-confirmed COVID-19 from Jinhua Municipal Central hospital through 27 January 2020. We found that compared to pharyngeal swab specimens, nucleic acid detection of COVID-19 in fecal specimens was equally accurate. And we found that patients with a positive stool test did not experience gastrointestinal symptoms and had nothing to do with the severity of the lung infection. These results may help to understand the clinical diagnosis and the changes in clinical parameters of COVID-19.</div>
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<Abstract><AbstractText>The emergence and spread of 2019 novel coronavirus-infected pneumonia (COVID-19) from Wuhan, China, it has spread globally. We extracted the data on 14 patients with laboratory-confirmed COVID-19 from Jinhua Municipal Central hospital through 27 January 2020. We found that compared to pharyngeal swab specimens, nucleic acid detection of COVID-19 in fecal specimens was equally accurate. And we found that patients with a positive stool test did not experience gastrointestinal symptoms and had nothing to do with the severity of the lung infection. These results may help to understand the clinical diagnosis and the changes in clinical parameters of COVID-19.</AbstractText>
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<ReferenceList><Title>REFERENCES</Title>
<Reference><Citation>Zhu N, Zhang D, Wang W, et al. A novel coronavirus from patients with pneumoniain China. N Engl J Med. 2020;382:727-733.</Citation>
</Reference>
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<Reference><Citation>Wang D, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020. https://doi.org/10.1001/jama.2020.1585</Citation>
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<Reference><Citation>Ding Y, He L, Zhang Q, et al. Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways. J Pathol. 2004;203(2):622-630.</Citation>
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<Reference><Citation>Zhang Y, Chen H, Zhu S, et al. Isolation of 2019-nCoV from a stool specimen of a laboratory-confirmed case of the coronavirus disease 2019 (COVID-19). China CDC Weekly. 2020;2(8):123-124.</Citation>
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<Reference><Citation>Guan W, Ni Z, Hu Y, et al. Clinical characteristics of 2019 novel coronavirus infection in China. N Engl J Med. 2020. https://doi.org/10.1056/NEJMoa2002032</Citation>
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<Reference><Citation>Zhang H, Kang Z, Gong H, et al. The digestive system is a potential route of 2019-nCov infection: a bioinformatics analysis based on single-cell transcriptomes. 2020. Preprint at https://www.biorxiv.org/content/10.1101/2020.01.30.927806v1</Citation>
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<Reference><Citation>Zhang W, Du RH, Li B, et al. Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes. Emerging Microbes Infect. 2020;9:386-389.</Citation>
</Reference>
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