Bovine respiratory syncytial virus seroprevalence and risk factors in non-vaccinated dairy cattle herds in Brazil
Identifieur interne : 000793 ( Ncbi/Merge ); précédent : 000792; suivant : 000794Bovine respiratory syncytial virus seroprevalence and risk factors in non-vaccinated dairy cattle herds in Brazil
Auteurs : Ingrid Bortolin Affonso Lux Hoppe ; Andréa Souza Ramos De Medeiros ; Clarice Weis Arns ; Samir Issa SamaraSource :
- BMC Veterinary Research [ 1746-6148 ] ; 2018.
Abstract
The cattle industry is one of the most important Brazilian agribusiness sectors and is a strong contributor to the national economy. Annually about 44.6 million calves are bred, which makes the optimal management of these animals extremely important. Several diseases can affect the initial stages of the bovine production chain, being the bovine respiratory syncytial virus (BRSV) one of the most relevant pathogens. This study aimed to characterize the epidemiology of BRSV infection in dairy cattle herds of São Paulo State, Brazil, using serological and risk factors analyses. For that, 1243 blood samples were collected of animals from 26 farms and a questionnaire about possible risk factors for BRSV prevalence was performed. The obtained blood sera were analyzed using virus neutralization test (VNT).
VNT results showed high BRSV prevalence in dairy cattle herds, reaching 79.5% of seropositivity. The BRSV seroprevalence among studied farms ranged from 40 to 100%. The analysis of risk factors indicated that the age group and the occurrence of coinfection with bovine herpesvirus 1 (BoHV-1) and bovine viral diarrhea virus 1 (BVDV-1) should be associated with a higher prevalence of BRSV, while natural suckling was considered a protective factor.
The study showed that adult animals over 1 year old are an important risk factor for the high seroprevalence of BRSV in herds. The high BRSV prevalence associated with BoHV-1 and BVDV-1 suggests that biosecurity measures should be applied in order to reduce viral dissemination. Additionally, the natural suckling may be an important management to protect calves from high BRSV seroprevalence.
Url:
DOI: 10.1186/s12917-018-1535-8
PubMed: 29945679
PubMed Central: 6020315
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Bovine respiratory syncytial virus seroprevalence and risk factors in non-vaccinated dairy cattle herds in Brazil</title>
<author><name sortKey="Hoppe, Ingrid Bortolin Affonso Lux" sort="Hoppe, Ingrid Bortolin Affonso Lux" uniqKey="Hoppe I" first="Ingrid Bortolin Affonso Lux" last="Hoppe">Ingrid Bortolin Affonso Lux Hoppe</name>
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<institution>Faculdade de Ciências Agrárias e Veterinárias (FCAV), Departamento de Medicina Veterinária Preventiva e Reprodução Animal,</institution>
<institution>Univ Estadual Paulista – UNESP,</institution>
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Via de Acesso Prof. Paulo Donato Castellane, km 05, Jaboticabal, São Paulo CEP: 14.884-900 Brazil</nlm:aff>
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<author><name sortKey="Medeiros, Andrea Souza Ramos De" sort="Medeiros, Andrea Souza Ramos De" uniqKey="Medeiros A" first="Andréa Souza Ramos De" last="Medeiros">Andréa Souza Ramos De Medeiros</name>
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Via de Acesso Prof. Paulo Donato Castellane, km 05, Jaboticabal, São Paulo CEP: 14.884-900 Brazil</nlm:aff>
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<author><name sortKey="Arns, Clarice Weis" sort="Arns, Clarice Weis" uniqKey="Arns C" first="Clarice Weis" last="Arns">Clarice Weis Arns</name>
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<author><name sortKey="Samara, Samir Issa" sort="Samara, Samir Issa" uniqKey="Samara S" first="Samir Issa" last="Samara">Samir Issa Samara</name>
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Via de Acesso Prof. Paulo Donato Castellane, km 05, Jaboticabal, São Paulo CEP: 14.884-900 Brazil</nlm:aff>
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<series><title level="j">BMC Veterinary Research</title>
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<front><div type="abstract" xml:lang="en"><sec><title>Background</title>
<p id="Par1">The cattle industry is one of the most important Brazilian agribusiness sectors and is a strong contributor to the national economy. Annually about 44.6 million calves are bred, which makes the optimal management of these animals extremely important. Several diseases can affect the initial stages of the bovine production chain, being the bovine respiratory syncytial virus (BRSV) one of the most relevant pathogens. This study aimed to characterize the epidemiology of BRSV infection in dairy cattle herds of São Paulo State, Brazil, using serological and risk factors analyses. For that, 1243 blood samples were collected of animals from 26 farms and a questionnaire about possible risk factors for BRSV prevalence was performed. The obtained blood sera were analyzed using virus neutralization test (VNT).</p>
</sec>
<sec><title>Results</title>
<p id="Par2">VNT results showed high BRSV prevalence in dairy cattle herds, reaching 79.5% of seropositivity. The BRSV seroprevalence among studied farms ranged from 40 to 100%. The analysis of risk factors indicated that the age group and the occurrence of coinfection with bovine herpesvirus 1 (BoHV-1) and bovine viral diarrhea virus 1 (BVDV-1) should be associated with a higher prevalence of BRSV, while natural suckling was considered a protective factor.</p>
</sec>
<sec><title>Conclusions</title>
<p id="Par3">The study showed that adult animals over 1 year old are an important risk factor for the high seroprevalence of BRSV in herds. The high BRSV prevalence associated with BoHV-1 and BVDV-1 suggests that biosecurity measures should be applied in order to reduce viral dissemination. Additionally, the natural suckling may be an important management to protect calves from high BRSV seroprevalence.</p>
</sec>
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</front>
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<author><name sortKey="Weary, Dm" uniqKey="Weary D">DM Weary</name>
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<pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">BMC Vet Res</journal-id>
<journal-id journal-id-type="iso-abbrev">BMC Vet. Res</journal-id>
<journal-title-group><journal-title>BMC Veterinary Research</journal-title>
</journal-title-group>
<issn pub-type="epub">1746-6148</issn>
<publisher><publisher-name>BioMed Central</publisher-name>
<publisher-loc>London</publisher-loc>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">29945679</article-id>
<article-id pub-id-type="pmc">6020315</article-id>
<article-id pub-id-type="publisher-id">1535</article-id>
<article-id pub-id-type="doi">10.1186/s12917-018-1535-8</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Bovine respiratory syncytial virus seroprevalence and risk factors in non-vaccinated dairy cattle herds in Brazil</article-title>
</title-group>
<contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-9946-8820</contrib-id>
<name><surname>Hoppe</surname>
<given-names>Ingrid Bortolin Affonso Lux</given-names>
</name>
<address><email>ibaffonso@gmail.com</email>
</address>
<xref ref-type="aff" rid="Aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Medeiros</surname>
<given-names>Andréa Souza Ramos de</given-names>
</name>
<address><email>andrea@fcav.unesp.br</email>
</address>
<xref ref-type="aff" rid="Aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Arns</surname>
<given-names>Clarice Weis</given-names>
</name>
<address><email>arns@unicamp.br</email>
</address>
<xref ref-type="aff" rid="Aff2">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Samara</surname>
<given-names>Samir Issa</given-names>
</name>
<address><email>samara@fcav.unesp.br</email>
</address>
<xref ref-type="aff" rid="Aff1">1</xref>
</contrib>
<aff id="Aff1"><label>1</label>
<institution-wrap><institution-id institution-id-type="ISNI">0000 0001 2188 478X</institution-id>
<institution-id institution-id-type="GRID">grid.410543.7</institution-id>
<institution>Faculdade de Ciências Agrárias e Veterinárias (FCAV), Departamento de Medicina Veterinária Preventiva e Reprodução Animal,</institution>
<institution>Univ Estadual Paulista – UNESP,</institution>
</institution-wrap>
Via de Acesso Prof. Paulo Donato Castellane, km 05, Jaboticabal, São Paulo CEP: 14.884-900 Brazil</aff>
<aff id="Aff2"><label>2</label>
Instituto de Biologia, Universidade Estadual de Campinas – UNICAMP, Cidade Universitária, Caixa-postal: 6109, Campinas, São Paulo CEP: 13.083-970 Brazil</aff>
</contrib-group>
<pub-date pub-type="epub"><day>27</day>
<month>6</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>27</day>
<month>6</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="collection"><year>2018</year>
</pub-date>
<volume>14</volume>
<elocation-id>208</elocation-id>
<history><date date-type="received"><day>17</day>
<month>5</month>
<year>2017</year>
</date>
<date date-type="accepted"><day>19</day>
<month>6</month>
<year>2018</year>
</date>
</history>
<permissions><copyright-statement>© The Author(s). 2018</copyright-statement>
<license license-type="OpenAccess"><license-p><bold>Open Access</bold>
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">http://creativecommons.org/licenses/by/4.0/</ext-link>
), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/publicdomain/zero/1.0/">http://creativecommons.org/publicdomain/zero/1.0/</ext-link>
) applies to the data made available in this article, unless otherwise stated.</license-p>
</license>
</permissions>
<abstract id="Abs1"><sec><title>Background</title>
<p id="Par1">The cattle industry is one of the most important Brazilian agribusiness sectors and is a strong contributor to the national economy. Annually about 44.6 million calves are bred, which makes the optimal management of these animals extremely important. Several diseases can affect the initial stages of the bovine production chain, being the bovine respiratory syncytial virus (BRSV) one of the most relevant pathogens. This study aimed to characterize the epidemiology of BRSV infection in dairy cattle herds of São Paulo State, Brazil, using serological and risk factors analyses. For that, 1243 blood samples were collected of animals from 26 farms and a questionnaire about possible risk factors for BRSV prevalence was performed. The obtained blood sera were analyzed using virus neutralization test (VNT).</p>
</sec>
<sec><title>Results</title>
<p id="Par2">VNT results showed high BRSV prevalence in dairy cattle herds, reaching 79.5% of seropositivity. The BRSV seroprevalence among studied farms ranged from 40 to 100%. The analysis of risk factors indicated that the age group and the occurrence of coinfection with bovine herpesvirus 1 (BoHV-1) and bovine viral diarrhea virus 1 (BVDV-1) should be associated with a higher prevalence of BRSV, while natural suckling was considered a protective factor.</p>
</sec>
<sec><title>Conclusions</title>
<p id="Par3">The study showed that adult animals over 1 year old are an important risk factor for the high seroprevalence of BRSV in herds. The high BRSV prevalence associated with BoHV-1 and BVDV-1 suggests that biosecurity measures should be applied in order to reduce viral dissemination. Additionally, the natural suckling may be an important management to protect calves from high BRSV seroprevalence.</p>
</sec>
</abstract>
<kwd-group xml:lang="en"><title>Keywords</title>
<kwd>Bovine respiratory syncytial virus</kwd>
<kwd>Seroprevalence</kwd>
<kwd>Risk factors</kwd>
<kwd>Dairy cattle herds</kwd>
</kwd-group>
<funding-group><award-group><funding-source><institution>Fundação de Amparo à Pesquisa do Estado de São Paulo (BR)</institution>
</funding-source>
<award-id>2010/15912-7</award-id>
<principal-award-recipient><name><surname>Samara</surname>
<given-names>Samir Issa</given-names>
</name>
</principal-award-recipient>
</award-group>
</funding-group>
<funding-group><award-group><funding-source><institution>Fundação de Amparo à Pesquisa do Estado de São Paulo (BR)</institution>
</funding-source>
<award-id>2010/06950-2</award-id>
<principal-award-recipient><name><surname>Hoppe</surname>
<given-names>Ingrid Bortolin Affonso Lux</given-names>
</name>
</principal-award-recipient>
</award-group>
</funding-group>
<custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name>
<meta-value>© The Author(s) 2018</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
</pmc>
<affiliations><list></list>
<tree><noCountry><name sortKey="Arns, Clarice Weis" sort="Arns, Clarice Weis" uniqKey="Arns C" first="Clarice Weis" last="Arns">Clarice Weis Arns</name>
<name sortKey="Hoppe, Ingrid Bortolin Affonso Lux" sort="Hoppe, Ingrid Bortolin Affonso Lux" uniqKey="Hoppe I" first="Ingrid Bortolin Affonso Lux" last="Hoppe">Ingrid Bortolin Affonso Lux Hoppe</name>
<name sortKey="Medeiros, Andrea Souza Ramos De" sort="Medeiros, Andrea Souza Ramos De" uniqKey="Medeiros A" first="Andréa Souza Ramos De" last="Medeiros">Andréa Souza Ramos De Medeiros</name>
<name sortKey="Samara, Samir Issa" sort="Samara, Samir Issa" uniqKey="Samara S" first="Samir Issa" last="Samara">Samir Issa Samara</name>
</noCountry>
</tree>
</affiliations>
</record>
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