Children's vaccines do not induce cross reactivity against SARS-CoV.
Identifieur interne : 000104 ( Ncbi/Merge ); précédent : 000103; suivant : 000105Children's vaccines do not induce cross reactivity against SARS-CoV.
Auteurs : Yang Yu [République populaire de Chine] ; Huali Jin ; Ze Chen ; Qingling L. Yu ; Yijie J. Ma ; Xiaolin L. Sun ; Bin WangSource :
- Journal of clinical pathology [ 0021-9746 ] ; 2007.
Descripteurs français
- KwdFr :
- Animaux, Anticorps antiviraux (sang), Enfant, Enfant d'âge préscolaire, Humains, Immunisation, Lymphocytes T (immunologie), Nourrisson, Réactions croisées (immunologie), Souris, Souris de lignée C57BL, Syndrome respiratoire aigu sévère (immunologie), Sérums immuns (immunologie), Test ELISA (), Vaccins (immunologie), Virus du SRAS (immunologie).
- MESH :
English descriptors
- KwdEn :
- Animals, Antibodies, Viral (blood), Child, Child, Preschool, Cross Reactions (immunology), Enzyme-Linked Immunosorbent Assay (methods), Humans, Immune Sera (immunology), Immunization, Infant, Mice, Mice, Inbred C57BL, SARS Virus (immunology), Severe Acute Respiratory Syndrome (immunology), T-Lymphocytes (immunology), Vaccines (immunology).
- MESH :
- chemical , blood : Antibodies, Viral.
- immunology : Cross Reactions, Immune Sera, SARS Virus, Severe Acute Respiratory Syndrome, T-Lymphocytes, Vaccines.
- methods : Enzyme-Linked Immunosorbent Assay.
- Animals, Child, Child, Preschool, Humans, Immunization, Infant, Mice, Mice, Inbred C57BL.
Abstract
In contrast with adults, children infected by severe acute respiratory syndrome-corona virus (SARS-CoV) develop milder clinical symptoms. Because of this, it is speculated that children vaccinated with various childhood vaccines might develop cross immunity against SARS-CoV. Antisera and T cells from mice immunised with various vaccines were used to determine whether they developed cross reactivity against SARS-CoV. The results showed no marked cross reactivity against SARS-CoV, which implies that the reduced symptoms among children infected by SARS-CoV may be caused by other factors.
DOI: 10.1136/jcp.2006.038893
PubMed: 17264247
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pubmed:17264247Le document en format XML
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<term>Enzyme-Linked Immunosorbent Assay (methods)</term>
<term>Humans</term>
<term>Immune Sera (immunology)</term>
<term>Immunization</term>
<term>Infant</term>
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<term>Mice, Inbred C57BL</term>
<term>SARS Virus (immunology)</term>
<term>Severe Acute Respiratory Syndrome (immunology)</term>
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<front><div type="abstract" xml:lang="en">In contrast with adults, children infected by severe acute respiratory syndrome-corona virus (SARS-CoV) develop milder clinical symptoms. Because of this, it is speculated that children vaccinated with various childhood vaccines might develop cross immunity against SARS-CoV. Antisera and T cells from mice immunised with various vaccines were used to determine whether they developed cross reactivity against SARS-CoV. The results showed no marked cross reactivity against SARS-CoV, which implies that the reduced symptoms among children infected by SARS-CoV may be caused by other factors.</div>
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