Influence of maternal immunity on the outcome of mutine coronavirus JHM infection in suckling mice
Identifieur interne : 000788 ( Ncbi/Curation ); précédent : 000787; suivant : 000789Influence of maternal immunity on the outcome of mutine coronavirus JHM infection in suckling mice
Auteurs : K. Pickel [Allemagne] ; M. A. Müller [Allemagne] ; V. Ter Meulen [Allemagne]Source :
- Medical Microbiology and Immunology [ 0300-8584 ] ; 1985.
Abstract
Adult C3H mice are resistant to intraperitoneal infection with murine coronavirus JHM, whereas suckling offspring of non-immune females are susceptible. Resistance can be conferred on suckling C3H mice by postnatal transmission of maternal immunity, if transfer preceeds infection. Suckling mice succumb to infection even when they receive maternal antibodies within 1 day after infection. Prenatal transmission alone without subsequent postnatal transmission of maternal immunity is not sufficient to provide resistance. Persistence of virus without clinical consequences was observed when the supply of breast milk anti-JHMV antibodies was terminated 5 days before infection. Immune reactions restricted by histocompatibility antigens do not play a crucial role in bestowing resistance. As neutralizing anti-JHM serum antibody titers of adult mice only rise sharply 5 to 7 days after infection, these results indicate that infection of adults can be arrested by immunological means but that, in addition, the rate of virus dissemination must be limited by other non-immunological mechanisms.
Url:
DOI: 10.1007/BF02123666
PubMed: 2987653
PubMed Central: 7087257
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000299
- to stream Pmc, to step Curation: Pour aller vers cette notice dans l'étape Curation :000299
- to stream Pmc, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000A92
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :000788
Links to Exploration step
PMC:7087257Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Influence of maternal immunity on the outcome of mutine coronavirus JHM infection in suckling mice</title><author><name sortKey="Pickel, K" sort="Pickel, K" uniqKey="Pickel K" first="K." last="Pickel">K. Pickel</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Institute for Virology and Immunobiology, Versbacher Str. 7, D-8700 Würzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Virology and Immunobiology, Versbacher Str. 7, D-8700 Würzburg</wicri:regionArea><wicri:noRegion>D-8700 Würzburg</wicri:noRegion><wicri:noRegion>D-8700 Würzburg</wicri:noRegion><wicri:noRegion>D-8700 Würzburg</wicri:noRegion></affiliation></author><author><name sortKey="Muller, M A" sort="Muller, M A" uniqKey="Muller M" first="M. A." last="Müller">M. A. Müller</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Institute for Virology and Immunobiology, Versbacher Str. 7, D-8700 Würzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Virology and Immunobiology, Versbacher Str. 7, D-8700 Würzburg</wicri:regionArea><wicri:noRegion>D-8700 Würzburg</wicri:noRegion><wicri:noRegion>D-8700 Würzburg</wicri:noRegion><wicri:noRegion>D-8700 Würzburg</wicri:noRegion></affiliation></author><author><name sortKey="Ter Meulen, V" sort="Ter Meulen, V" uniqKey="Ter Meulen V" first="V." last="Ter Meulen">V. Ter Meulen</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Institute for Virology and Immunobiology, Versbacher Str. 7, D-8700 Würzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Virology and Immunobiology, Versbacher Str. 7, D-8700 Würzburg</wicri:regionArea><wicri:noRegion>D-8700 Würzburg</wicri:noRegion><wicri:noRegion>D-8700 Würzburg</wicri:noRegion><wicri:noRegion>D-8700 Würzburg</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">2987653</idno><idno type="pmc">7087257</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087257</idno><idno type="RBID">PMC:7087257</idno><idno type="doi">10.1007/BF02123666</idno><date when="1985">1985</date><idno type="wicri:Area/Pmc/Corpus">000299</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000299</idno><idno type="wicri:Area/Pmc/Curation">000299</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000299</idno><idno type="wicri:Area/Pmc/Checkpoint">000A92</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000A92</idno><idno type="wicri:Area/Ncbi/Merge">000788</idno><idno type="wicri:Area/Ncbi/Curation">000788</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Influence of maternal immunity on the outcome of mutine coronavirus JHM infection in suckling mice</title><author><name sortKey="Pickel, K" sort="Pickel, K" uniqKey="Pickel K" first="K." last="Pickel">K. Pickel</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Institute for Virology and Immunobiology, Versbacher Str. 7, D-8700 Würzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Virology and Immunobiology, Versbacher Str. 7, D-8700 Würzburg</wicri:regionArea><wicri:noRegion>D-8700 Würzburg</wicri:noRegion><wicri:noRegion>D-8700 Würzburg</wicri:noRegion><wicri:noRegion>D-8700 Würzburg</wicri:noRegion></affiliation></author><author><name sortKey="Muller, M A" sort="Muller, M A" uniqKey="Muller M" first="M. A." last="Müller">M. A. Müller</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Institute for Virology and Immunobiology, Versbacher Str. 7, D-8700 Würzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Virology and Immunobiology, Versbacher Str. 7, D-8700 Würzburg</wicri:regionArea><wicri:noRegion>D-8700 Würzburg</wicri:noRegion><wicri:noRegion>D-8700 Würzburg</wicri:noRegion><wicri:noRegion>D-8700 Würzburg</wicri:noRegion></affiliation></author><author><name sortKey="Ter Meulen, V" sort="Ter Meulen, V" uniqKey="Ter Meulen V" first="V." last="Ter Meulen">V. Ter Meulen</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Institute for Virology and Immunobiology, Versbacher Str. 7, D-8700 Würzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Virology and Immunobiology, Versbacher Str. 7, D-8700 Würzburg</wicri:regionArea><wicri:noRegion>D-8700 Würzburg</wicri:noRegion><wicri:noRegion>D-8700 Würzburg</wicri:noRegion><wicri:noRegion>D-8700 Würzburg</wicri:noRegion></affiliation></author></analytic><series><title level="j">Medical Microbiology and Immunology</title><idno type="ISSN">0300-8584</idno><idno type="eISSN">1432-1831</idno><imprint><date when="1985">1985</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Adult C3H mice are resistant to intraperitoneal infection with murine coronavirus JHM, whereas suckling offspring of non-immune females are susceptible. Resistance can be conferred on suckling C3H mice by postnatal transmission of maternal immunity, if transfer preceeds infection. Suckling mice succumb to infection even when they receive maternal antibodies within 1 day after infection. Prenatal transmission alone without subsequent postnatal transmission of maternal immunity is not sufficient to provide resistance. Persistence of virus without clinical consequences was observed when the supply of breast milk anti-JHMV antibodies was terminated 5 days before infection. Immune reactions restricted by histocompatibility antigens do not play a crucial role in bestowing resistance. As neutralizing anti-JHM serum antibody titers of adult mice only rise sharply 5 to 7 days after infection, these results indicate that infection of adults can be arrested by immunological means but that, in addition, the rate of virus dissemination must be limited by other non-immunological mechanisms.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Borthistle, Bk" uniqKey="Borthistle B">BK Borthistle</name></author><author><name sortKey="Kubo, Rt" uniqKey="Kubo R">RT Kubo</name></author><author><name sortKey="Brown, Wr" uniqKey="Brown W">WR Brown</name></author><author><name sortKey="Grey, Hm" uniqKey="Grey H">HM Grey</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Brambell, Fwr" uniqKey="Brambell F">FWR Brambell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guyer, Rl" uniqKey="Guyer R">RL Guyer</name></author><author><name sortKey="Koshland, Me" uniqKey="Koshland M">ME Koshland</name></author><author><name sortKey="Knopf, Pm" uniqKey="Knopf P">PM Knopf</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Halliday, R" uniqKey="Halliday R">R Halliday</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Halliday, R" uniqKey="Halliday R">R Halliday</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mathot, C" uniqKey="Mathot C">C Mathot</name></author><author><name sortKey="Scher, S" uniqKey="Scher S">S Scher</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mirand, Ea" uniqKey="Mirand E">EA Mirand</name></author><author><name sortKey="Grace, Jt" uniqKey="Grace J">JT Grace</name></author><author><name sortKey="Buffett, Rf" uniqKey="Buffett R">RF Buffett</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Morris, Ig" uniqKey="Morris I">IG Morris</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nagashima, K" uniqKey="Nagashima K">K Nagashima</name></author><author><name sortKey="Wege, H" uniqKey="Wege H">H Wege</name></author><author><name sortKey="Meyermann, R" uniqKey="Meyermann R">R Meyermann</name></author><author><name sortKey="Ter Meulen, V" uniqKey="Ter Meulen V">V ter Meulen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nagashima, K" uniqKey="Nagashima K">K Nagashima</name></author><author><name sortKey="Wege, H" uniqKey="Wege H">H Wege</name></author><author><name sortKey="Meyermann, R" uniqKey="Meyermann R">R Meyermann</name></author><author><name sortKey="Ter Meulen, V" uniqKey="Ter Meulen V">V ter Meulen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nagura, H" uniqKey="Nagura H">H Nagura</name></author><author><name sortKey="Nakane, Pk" uniqKey="Nakane P">PK Nakane</name></author><author><name sortKey="Brown, Wr" uniqKey="Brown W">WR Brown</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pickel, K" uniqKey="Pickel K">K Pickel</name></author><author><name sortKey="Muller, Ma" uniqKey="Muller M">MA Müller</name></author><author><name sortKey="Ter Meulen, V" uniqKey="Ter Meulen V">V ter Meulen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pittard, Wb" uniqKey="Pittard W">WB Pittard</name></author><author><name sortKey="Polmar, Sh" uniqKey="Polmar S">SH Polmar</name></author><author><name sortKey="Fanaroff, Aa" uniqKey="Fanaroff A">AA Fanaroff</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Seelig, Ll" uniqKey="Seelig L">LL Seelig</name></author><author><name sortKey="Beer, Ae" uniqKey="Beer A">AE Beer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Taguchi, F" uniqKey="Taguchi F">F Taguchi</name></author><author><name sortKey="Yamada, A" uniqKey="Yamada A">A Yamada</name></author><author><name sortKey="Fujiwara, K" uniqKey="Fujiwara K">K Fujiwara</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wege, H" uniqKey="Wege H">H Wege</name></author><author><name sortKey="Koga, M" uniqKey="Koga M">M Koga</name></author><author><name sortKey="Wege, H" uniqKey="Wege H">H Wege</name></author><author><name sortKey="Ter Meulen, V" uniqKey="Ter Meulen V">V ter Meulen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wege, H" uniqKey="Wege H">H Wege</name></author><author><name sortKey="Siddell, S" uniqKey="Siddell S">S Siddell</name></author><author><name sortKey="Ter Meulen, V" uniqKey="Ter Meulen V">V ter Meulen</name></author></analytic></biblStruct></listBibl></div1></back></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV2/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000788 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 000788 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= CovidV2
|flux= Ncbi
|étape= Curation
|type= RBID
|clé= PMC:7087257
|texte= Influence of maternal immunity on the outcome of mutine coronavirus JHM infection in suckling mice
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:2987653" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \
| NlmPubMed2Wicri -a CovidV2
| This area was generated with Dilib version V0.6.33. |  |