Rhesus macaque θ-defensin RTD-1 inhibits proinflammatory cytokine secretion and gene expression by inhibiting the activation of NF-κB and MAPK pathways
Identifieur interne : 000544 ( Ncbi/Curation ); précédent : 000543; suivant : 000545Rhesus macaque θ-defensin RTD-1 inhibits proinflammatory cytokine secretion and gene expression by inhibiting the activation of NF-κB and MAPK pathways
Auteurs : Prasad Tongaonkar ; Katie K. Trinh ; Justin B. Schaal ; Dat Tran ; Percio S. Gulko ; André J. Ouellette ; Michael E. SelstedSource :
- Journal of Leukocyte Biology [ 0741-5400 ] ; 2015.
Abstract
The anti-inflammatory effects of θ-defensin RTD-1 are mediated by cell signaling pathways that down-regulate expression of pro-inflammatory cytokines.
Url:
DOI: 10.1189/jlb.3A0315-102R
PubMed: 26269197
PubMed Central: 4661038
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