[Epidemiological analysis on a family cluster of COVID-19].
Identifieur interne : 000D63 ( Ncbi/Checkpoint ); précédent : 000D62; suivant : 000D64[Epidemiological analysis on a family cluster of COVID-19].
Auteurs : Y Y Qiu [République populaire de Chine] ; S Q Wang [République populaire de Chine] ; X L Wang [République populaire de Chine] ; W X Lu [République populaire de Chine] ; D. Qiao [République populaire de Chine] ; J B Li [République populaire de Chine] ; Y Y Gu [République populaire de Chine] ; Y. Zeng [République populaire de Chine] ; Y. Chen [République populaire de Chine] ; W Z Bai [République populaire de Chine] ; B L Xu [République populaire de Chine] ; T W Han [République populaire de Chine]Source :
- Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi [ 0254-6450 ] ; 2020.
Abstract
Objective: To understand the possible transmission route of a family cluster of COVID-19 in Zhengzhou and the potential infectivity of COVID-19 in incubation period, and provide scientific evidence for the timely control of infectious source and curb the spread of the epidemic. Methods: Epidemiological investigation was conducted for a family cluster of COVID-19 (8 cases) with descriptive epidemiological method, and respiratory tract samples of the cases were collected for the nucleic acid detection of 2019-nCoV by RT-PCR. Results: Two primary cases, which occurred on 31 January and 1 February, 2020, respectively, had a common exposure history in Wuhan. The other six family members had onsets on 30 January, 31 January, 1 February (three cases) and 3 February, 2020. Conclusions: In this family cluster of COVID-19, six family members were infected through common family exposure to the 2 primary cases. Five secondary cases had onsets earlier than or on the same day as the primary cases, indicating that COVID-19 is contagious in incubation period, and the home isolation in the early phase of the epidemic might lead to the risk of family cluster of COVID-19.
DOI: 10.3760/cma.j.cn112338-20200221-00147
PubMed: 32133831
Affiliations:
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<front><div type="abstract" xml:lang="en"><b>Objective:</b>
To understand the possible transmission route of a family cluster of COVID-19 in Zhengzhou and the potential infectivity of COVID-19 in incubation period, and provide scientific evidence for the timely control of infectious source and curb the spread of the epidemic. <b>Methods:</b>
Epidemiological investigation was conducted for a family cluster of COVID-19 (8 cases) with descriptive epidemiological method, and respiratory tract samples of the cases were collected for the nucleic acid detection of 2019-nCoV by RT-PCR. <b>Results:</b>
Two primary cases, which occurred on 31 January and 1 February, 2020, respectively, had a common exposure history in Wuhan. The other six family members had onsets on 30 January, 31 January, 1 February (three cases) and 3 February, 2020. <b>Conclusions:</b>
In this family cluster of COVID-19, six family members were infected through common family exposure to the 2 primary cases. Five secondary cases had onsets earlier than or on the same day as the primary cases, indicating that COVID-19 is contagious in incubation period, and the home isolation in the early phase of the epidemic might lead to the risk of family cluster of COVID-19.</div>
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