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Duration of challenge immunity to coronavirus JHM in mice

Identifieur interne : 001C72 ( Main/Merge ); précédent : 001C71; suivant : 001C73

Duration of challenge immunity to coronavirus JHM in mice

Auteurs : S. W. Barthold ; A. L. Smith

Source :

RBID : Pascal:90-0072389

Descripteurs français

English descriptors

Abstract

The duration of challenge resistance in mice immunized with mouse hepatitis virus (MHV) strain JHM was examined as a model of immunity to corona-virus infection. Genetically susceptible BALB/cByJ mice were immunized by intranasal (i.n.) or per os (p.o.) inoculation with MHV-JHM or sterile tissue culture fluid (sham) then challenged i.n. with MHV-JHM or sterile tissue culture fluid 1, 6 or 12 months later

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Pascal:90-0072389

Le document en format XML

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<name sortKey="Smith, A L" sort="Smith, A L" uniqKey="Smith A" first="A. L." last="Smith">A. L. Smith</name>
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<term>Animal model</term>
<term>Comparative study</term>
<term>Immune response</term>
<term>Immunity</term>
<term>Immunization</term>
<term>Mouse</term>
<term>Murine coronavirus</term>
<term>Murine hepatitis virus</term>
<term>Reinfection</term>
<term>Resistance</term>
<term>Respiratory disease</term>
<term>Route of administration</term>
<term>Sensitivity</term>
<term>Strain</term>
<term>Viral disease</term>
<term>Virus multiplication</term>
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<keywords scheme="Pascal" xml:lang="fr">
<term>Immunité</term>
<term>Immunisation</term>
<term>Réinfection</term>
<term>Voie administration</term>
<term>Sensibilité</term>
<term>Résistance</term>
<term>Multiplication virus</term>
<term>Réponse immune</term>
<term>Etude comparative</term>
<term>Souris</term>
<term>Modèle animal</term>
<term>Souche</term>
<term>Virus hépatite murine</term>
<term>Coronavirus murin</term>
<term>Virose</term>
<term>Appareil respiratoire pathologie</term>
<term>Souris BALB/c</term>
<term>Tissu lymphoïde associé intestin</term>
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<div type="abstract" xml:lang="en">The duration of challenge resistance in mice immunized with mouse hepatitis virus (MHV) strain JHM was examined as a model of immunity to corona-virus infection. Genetically susceptible BALB/cByJ mice were immunized by intranasal (i.n.) or per os (p.o.) inoculation with MHV-JHM or sterile tissue culture fluid (sham) then challenged i.n. with MHV-JHM or sterile tissue culture fluid 1, 6 or 12 months later</div>
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EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV2/Data/Main/Merge
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{{Explor lien
   |wiki=    Wicri/Sante
   |area=    CovidV2
   |flux=    Main
   |étape=   Merge
   |type=    RBID
   |clé=     Pascal:90-0072389
   |texte=   Duration of challenge immunity to coronavirus JHM in mice
}}

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