High-throughput virtual screening and docking studies of matrix protein vp40 of ebola virus
Identifieur interne : 001241 ( Main/Merge ); précédent : 001240; suivant : 001242High-throughput virtual screening and docking studies of matrix protein vp40 of ebola virus
Auteurs : Thangaraju Tamilvanan ; Waheeta HopperSource :
- Bioinformation [ 0973-8894 ] ; 2013.
Abstract
Url:
DOI: 10.6026/97320630009286
PubMed: 23559747
PubMed Central: 3607187
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000823
- to stream Pmc, to step Curation: 000823
- to stream Pmc, to step Checkpoint: 000693
- to stream Ncbi, to step Merge: 000377
- to stream Ncbi, to step Curation: 000377
- to stream Ncbi, to step Checkpoint: 000377
Links to Exploration step
PMC:3607187Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">High-throughput virtual screening and docking studies of matrix protein vp40 of ebola virus</title>
<author><name sortKey="Tamilvanan, Thangaraju" sort="Tamilvanan, Thangaraju" uniqKey="Tamilvanan T" first="Thangaraju" last="Tamilvanan">Thangaraju Tamilvanan</name>
</author>
<author><name sortKey="Hopper, Waheeta" sort="Hopper, Waheeta" uniqKey="Hopper W" first="Waheeta" last="Hopper">Waheeta Hopper</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">23559747</idno>
<idno type="pmc">3607187</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607187</idno>
<idno type="RBID">PMC:3607187</idno>
<idno type="doi">10.6026/97320630009286</idno>
<date when="2013">2013</date>
<idno type="wicri:Area/Pmc/Corpus">000823</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000823</idno>
<idno type="wicri:Area/Pmc/Curation">000823</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000823</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000693</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000693</idno>
<idno type="wicri:Area/Ncbi/Merge">000377</idno>
<idno type="wicri:Area/Ncbi/Curation">000377</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000377</idno>
<idno type="wicri:doubleKey">0973-8894:2013:Tamilvanan T:high:throughput:virtual</idno>
<idno type="wicri:Area/Main/Merge">001241</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">High-throughput virtual screening and docking studies of matrix protein vp40 of ebola virus</title>
<author><name sortKey="Tamilvanan, Thangaraju" sort="Tamilvanan, Thangaraju" uniqKey="Tamilvanan T" first="Thangaraju" last="Tamilvanan">Thangaraju Tamilvanan</name>
</author>
<author><name sortKey="Hopper, Waheeta" sort="Hopper, Waheeta" uniqKey="Hopper W" first="Waheeta" last="Hopper">Waheeta Hopper</name>
</author>
</analytic>
<series><title level="j">Bioinformation</title>
<idno type="ISSN">0973-8894</idno>
<idno type="eISSN">0973-2063</idno>
<imprint><date when="2013">2013</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p><italic>Ebolavirus</italic>
, a member of the <italic>Filoviridae</italic>
family of negative-sense RNA viruses, causes severe haemorrhagic fever leading up to 90%
lethality. <italic>Ebolavirus</italic>
matrix protein VP40 is involved in the virus assembly and budding process. The RNA binding pocket of VP40
is considered as the drug target site for structure based drug design. High Throughput Virtual Screening and molecular docking
studies were employed to find the suitable inhibitors against VP40. Ten compounds showing good glide score and glide energy as
well as interaction with specific amino acid residues were short listed as drug leads. These small molecule inhibitors could be
potent inhibitors for VP40 matrix protein by blocking virus assembly and budding process.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Borio, L" uniqKey="Borio L">L Borio</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bray, M" uniqKey="Bray M">M Bray</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Atlas, Rm" uniqKey="Atlas R">RM Atlas</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Adrian, M" uniqKey="Adrian M">M Adrian</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Towner, Js" uniqKey="Towner J">JS Towner</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Sullivan, Nj" uniqKey="Sullivan N">NJ Sullivan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hevey, M" uniqKey="Hevey M">M Hevey</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rao, M" uniqKey="Rao M">M Rao</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Riemenschneider, J" uniqKey="Riemenschneider J">J Riemenschneider</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mellquist Riemenschneider, Jl" uniqKey="Mellquist Riemenschneider J">JL Mellquist-Riemenschneider</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jones, Sm" uniqKey="Jones S">SM Jones</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wang, D" uniqKey="Wang D">D Wang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wang, D" uniqKey="Wang D">D Wang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Swenson, Dl" uniqKey="Swenson D">DL Swenson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Warfield, Kl" uniqKey="Warfield K">KL Warfield</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Swenson, Dl" uniqKey="Swenson D">DL Swenson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hevey, M" uniqKey="Hevey M">M Hevey</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wilson, Ja" uniqKey="Wilson J">JA Wilson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Geisbert, Tw" uniqKey="Geisbert T">TW Geisbert</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bavari, S" uniqKey="Bavari S">S Bavari</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gomis Ruth, Fx" uniqKey="Gomis Ruth F">FX Gomis-Rüth </name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ruigrok, Rw" uniqKey="Ruigrok R">RW Ruigrok</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Timmins, J" uniqKey="Timmins J">J Timmins</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kaptur, Pe" uniqKey="Kaptur P">PE Kaptur</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Coronel, Ec" uniqKey="Coronel E">EC Coronel</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Stricker, R" uniqKey="Stricker R">R Stricker</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Schmitt, Ap" uniqKey="Schmitt A">AP Schmitt</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Dessen, A" uniqKey="Dessen A">A Dessen</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Berman, Hm" uniqKey="Berman H">HM Berman</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Lipinski, Ca" uniqKey="Lipinski C">CA Lipinski</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Laskowski, Ra" uniqKey="Laskowski R">RA Laskowski</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Narayanan, K" uniqKey="Narayanan K">K Narayanan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ahmed, M" uniqKey="Ahmed M">M Ahmed</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Von, Kc" uniqKey="Von K">KC Von</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Harty, Rn" uniqKey="Harty R">RN Harty</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Timmins, J" uniqKey="Timmins J">J Timmins</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Martin Serrano, J" uniqKey="Martin Serrano J">J Martin-Serrano</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Arthur, Jg" uniqKey="Arthur J">JG Arthur</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Aman, Mj" uniqKey="Aman M">MJ Aman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mike, Cw" uniqKey="Mike C">CW Mike</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jahrling, Pb" uniqKey="Jahrling P">PB Jahrling</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Barrientos, Lg" uniqKey="Barrientos L">LG Barrientos</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV2/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001241 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 001241 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= CovidV2 |flux= Main |étape= Merge |type= RBID |clé= PMC:3607187 |texte= High-throughput virtual screening and docking studies of matrix protein vp40 of ebola virus }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Merge/RBID.i -Sk "pubmed:23559747" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Merge/biblio.hfd \ | NlmPubMed2Wicri -a CovidV2
![]() | This area was generated with Dilib version V0.6.33. | ![]() |