Pelargonium sidoides radix extract EPs 7630 reduces rhinovirus infection through modulation of viral binding proteins on human bronchial epithelial cells
Identifieur interne : 000D74 ( Main/Merge ); précédent : 000D73; suivant : 000D75Pelargonium sidoides radix extract EPs 7630 reduces rhinovirus infection through modulation of viral binding proteins on human bronchial epithelial cells
Auteurs : Michael Roth ; Lei Fang ; Daiana Stolz ; Michael TammSource :
- PLoS ONE [ 1932-6203 ] ; 2019.
Abstract
Bronchial epithelial cells are the first target cell for rhinovirus infection. The course of viral infections in patients with acute bronchitis, asthma and COPD can be improved by oral application of
Url:
DOI: 10.1371/journal.pone.0210702
PubMed: 30707726
PubMed Central: 6358071
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000999
- to stream Pmc, to step Curation: 000999
- to stream Pmc, to step Checkpoint: 000281
- to stream Ncbi, to step Merge: 000842
- to stream Ncbi, to step Curation: 000842
- to stream Ncbi, to step Checkpoint: 000842
Links to Exploration step
PMC:6358071Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en"><italic>Pelargonium sidoides</italic>
radix extract EPs 7630 reduces rhinovirus infection through modulation of viral binding proteins on human bronchial epithelial cells</title>
<author><name sortKey="Roth, Michael" sort="Roth, Michael" uniqKey="Roth M" first="Michael" last="Roth">Michael Roth</name>
<affiliation><nlm:aff id="aff001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Fang, Lei" sort="Fang, Lei" uniqKey="Fang L" first="Lei" last="Fang">Lei Fang</name>
<affiliation><nlm:aff id="aff001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Stolz, Daiana" sort="Stolz, Daiana" uniqKey="Stolz D" first="Daiana" last="Stolz">Daiana Stolz</name>
<affiliation><nlm:aff id="aff001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Tamm, Michael" sort="Tamm, Michael" uniqKey="Tamm M" first="Michael" last="Tamm">Michael Tamm</name>
<affiliation><nlm:aff id="aff001"></nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">30707726</idno>
<idno type="pmc">6358071</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358071</idno>
<idno type="RBID">PMC:6358071</idno>
<idno type="doi">10.1371/journal.pone.0210702</idno>
<date when="2019">2019</date>
<idno type="wicri:Area/Pmc/Corpus">000999</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000999</idno>
<idno type="wicri:Area/Pmc/Curation">000999</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000999</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000281</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000281</idno>
<idno type="wicri:Area/Ncbi/Merge">000842</idno>
<idno type="wicri:Area/Ncbi/Curation">000842</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000842</idno>
<idno type="wicri:Area/Main/Merge">000D74</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main"><italic>Pelargonium sidoides</italic>
radix extract EPs 7630 reduces rhinovirus infection through modulation of viral binding proteins on human bronchial epithelial cells</title>
<author><name sortKey="Roth, Michael" sort="Roth, Michael" uniqKey="Roth M" first="Michael" last="Roth">Michael Roth</name>
<affiliation><nlm:aff id="aff001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Fang, Lei" sort="Fang, Lei" uniqKey="Fang L" first="Lei" last="Fang">Lei Fang</name>
<affiliation><nlm:aff id="aff001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Stolz, Daiana" sort="Stolz, Daiana" uniqKey="Stolz D" first="Daiana" last="Stolz">Daiana Stolz</name>
<affiliation><nlm:aff id="aff001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Tamm, Michael" sort="Tamm, Michael" uniqKey="Tamm M" first="Michael" last="Tamm">Michael Tamm</name>
<affiliation><nlm:aff id="aff001"></nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">PLoS ONE</title>
<idno type="eISSN">1932-6203</idno>
<imprint><date when="2019">2019</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Bronchial epithelial cells are the first target cell for rhinovirus infection. The course of viral infections in patients with acute bronchitis, asthma and COPD can be improved by oral application of <italic>Pelargonium sidoides</italic>
radix extract; however, the mechanism is not well understood. This study investigated the <italic>in vitro</italic>
effect of <italic>Pelargonium sidoides</italic>
radix extract (EPs 7630) on the expression of virus binding cell membrane and host defence supporting proteins on primary human bronchial epithelial cells (hBEC). Cells were isolated from patients with severe asthma (n = 6), moderate COPD (n = 6) and non-diseased controls (n = 6). Protein expression was determined by Western-blot and immunofluorescence. Rhinovirus infection was determined by immunofluorescence as well as by polymerase chain reaction. Cell survival was determined by manual cell count after live/death immunofluorescence staining. All parameters were determined over a period of 3 days. The results show that EPs 7630 concentration-dependently and significantly increased hBEC survival after rhinovirus infection. This effect was paralleled by decreased expression of the inducible co-stimulator (ICOS), its ligand ICOSL and cell surface calreticulin (C1qR). In contrast, EPs 7630 up-regulated the expression of the host defence supporting proteins β-defensin-1 and SOCS-1, both in rhinovirus infected and un-infected hBEC. The expression of other virus interacting cell membrane proteins such as MyD88, TRL2/4 or ICAM-1 was not altered by EPs 7630. The results indicate that EPs 7630 may reduce rhinovirus infection of human primary BEC by down-regulating cell membrane docking proteins and up-regulating host defence proteins.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Looi, K" uniqKey="Looi K">K Looi</name>
</author>
<author><name sortKey="Buckley, Ag" uniqKey="Buckley A">AG Buckley</name>
</author>
<author><name sortKey="Rigby, Pj" uniqKey="Rigby P">PJ Rigby</name>
</author>
<author><name sortKey="Garratt, Lw" uniqKey="Garratt L">LW Garratt</name>
</author>
<author><name sortKey="Iosifidis, T" uniqKey="Iosifidis T">T Iosifidis</name>
</author>
<author><name sortKey="Zosky, Gr" uniqKey="Zosky G">GR Zosky</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wilkinson, Tma" uniqKey="Wilkinson T">TMA Wilkinson</name>
</author>
<author><name sortKey="Aris, E" uniqKey="Aris E">E Aris</name>
</author>
<author><name sortKey="Bourne, S" uniqKey="Bourne S">S Bourne</name>
</author>
<author><name sortKey="Clarke, Sc" uniqKey="Clarke S">SC Clarke</name>
</author>
<author><name sortKey="Peeters, M" uniqKey="Peeters M">M Peeters</name>
</author>
<author><name sortKey="Pascal, Tg" uniqKey="Pascal T">TG Pascal</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zheng, Xy" uniqKey="Zheng X">XY Zheng</name>
</author>
<author><name sortKey="Xu, Yj" uniqKey="Xu Y">YJ Xu</name>
</author>
<author><name sortKey="Guan, Wj" uniqKey="Guan W">WJ Guan</name>
</author>
<author><name sortKey="Lin, Lf" uniqKey="Lin L">LF Lin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ritchie, Ai" uniqKey="Ritchie A">AI Ritchie</name>
</author>
<author><name sortKey="Farne, Ha" uniqKey="Farne H">HA Farne</name>
</author>
<author><name sortKey="Singanayagam, A" uniqKey="Singanayagam A">A Singanayagam</name>
</author>
<author><name sortKey="Jackson, Dj" uniqKey="Jackson D">DJ Jackson</name>
</author>
<author><name sortKey="Mallia, P" uniqKey="Mallia P">P Mallia</name>
</author>
<author><name sortKey="Johnston, Sl" uniqKey="Johnston S">SL Johnston</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Thibaut, Hj" uniqKey="Thibaut H">HJ Thibaut</name>
</author>
<author><name sortKey="Lacroix, C" uniqKey="Lacroix C">C Lacroix</name>
</author>
<author><name sortKey="De Palma, Am" uniqKey="De Palma A">AM De Palma</name>
</author>
<author><name sortKey="Franco, D" uniqKey="Franco D">D Franco</name>
</author>
<author><name sortKey="Decramer, M" uniqKey="Decramer M">M Decramer</name>
</author>
<author><name sortKey="Neyts, J" uniqKey="Neyts J">J Neyts</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bao, Y" uniqKey="Bao Y">Y Bao</name>
</author>
<author><name sortKey="Gao, Y" uniqKey="Gao Y">Y Gao</name>
</author>
<author><name sortKey="Koch, E" uniqKey="Koch E">E Koch</name>
</author>
<author><name sortKey="Pan, X" uniqKey="Pan X">X Pan</name>
</author>
<author><name sortKey="Jin, Y" uniqKey="Jin Y">Y Jin</name>
</author>
<author><name sortKey="Cui, X" uniqKey="Cui X">X Cui</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Helfer, M" uniqKey="Helfer M">M Helfer</name>
</author>
<author><name sortKey="Koppensteiner, H" uniqKey="Koppensteiner H">H Koppensteiner</name>
</author>
<author><name sortKey="Schneider, M" uniqKey="Schneider M">M Schneider</name>
</author>
<author><name sortKey="Rebensburg, S" uniqKey="Rebensburg S">S Rebensburg</name>
</author>
<author><name sortKey="Forcisi, S" uniqKey="Forcisi S">S Forcisi</name>
</author>
<author><name sortKey="Muller, C" uniqKey="Muller C">C Müller</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tahan, F" uniqKey="Tahan F">F Tahan</name>
</author>
<author><name sortKey="Yaman, M" uniqKey="Yaman M">M Yaman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Patiroglu, T" uniqKey="Patiroglu T">T Patiroglu</name>
</author>
<author><name sortKey="Tunc, A" uniqKey="Tunc A">A Tunc</name>
</author>
<author><name sortKey="Eke Gungor, H" uniqKey="Eke Gungor H">H Eke Gungor</name>
</author>
<author><name sortKey="Unal, E" uniqKey="Unal E">E Unal</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kamin, W" uniqKey="Kamin W">W Kamin</name>
</author>
<author><name sortKey="Maydannik, V" uniqKey="Maydannik V">V Maydannik</name>
</author>
<author><name sortKey="Malek, Fa" uniqKey="Malek F">FA Malek</name>
</author>
<author><name sortKey="Kieser, M" uniqKey="Kieser M">M Kieser</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kamin, W" uniqKey="Kamin W">W Kamin</name>
</author>
<author><name sortKey="Ilyenko, Li" uniqKey="Ilyenko L">LI Ilyenko</name>
</author>
<author><name sortKey="Malek, Fa" uniqKey="Malek F">FA Malek</name>
</author>
<author><name sortKey="Kieser, M" uniqKey="Kieser M">M Kieser</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Michaelis, M" uniqKey="Michaelis M">M Michaelis</name>
</author>
<author><name sortKey="Doerr, Hw" uniqKey="Doerr H">HW Doerr</name>
</author>
<author><name sortKey="Cinatl, J" uniqKey="Cinatl J">J Cinatl</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Theisen, Ll" uniqKey="Theisen L">LL Theisen</name>
</author>
<author><name sortKey="Muller, Cp" uniqKey="Muller C">CP Muller</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Shukla, Sd" uniqKey="Shukla S">SD Shukla</name>
</author>
<author><name sortKey="Hansbro, Pm" uniqKey="Hansbro P">PM Hansbro</name>
</author>
<author><name sortKey="Walters, Eh" uniqKey="Walters E">EH Walters</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Traub, S" uniqKey="Traub S">S Traub</name>
</author>
<author><name sortKey="Nikonova, A" uniqKey="Nikonova A">A Nikonova</name>
</author>
<author><name sortKey="Carruthers, A" uniqKey="Carruthers A">A Carruthers</name>
</author>
<author><name sortKey="Dunmore, R" uniqKey="Dunmore R">R Dunmore</name>
</author>
<author><name sortKey="Vousden, Ka" uniqKey="Vousden K">KA Vousden</name>
</author>
<author><name sortKey="Gogsadze, L" uniqKey="Gogsadze L">L Gogsadze</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mukhopadhyay, S" uniqKey="Mukhopadhyay S">S Mukhopadhyay</name>
</author>
<author><name sortKey="Malik, P" uniqKey="Malik P">P Malik</name>
</author>
<author><name sortKey="Arora, Sk" uniqKey="Arora S">SK Arora</name>
</author>
<author><name sortKey="Mukherjee, Tk" uniqKey="Mukherjee T">TK Mukherjee</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Shukla, Sd" uniqKey="Shukla S">SD Shukla</name>
</author>
<author><name sortKey="Mahmood, Mq" uniqKey="Mahmood M">MQ Mahmood</name>
</author>
<author><name sortKey="Weston, S" uniqKey="Weston S">S Weston</name>
</author>
<author><name sortKey="Latham, R" uniqKey="Latham R">R Latham</name>
</author>
<author><name sortKey="Muller, Hk" uniqKey="Muller H">HK Muller</name>
</author>
<author><name sortKey="Sohal, Ss" uniqKey="Sohal S">SS Sohal</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Stanciu, La" uniqKey="Stanciu L">LA Stanciu</name>
</author>
<author><name sortKey="Bellettato, Cm" uniqKey="Bellettato C">CM Bellettato</name>
</author>
<author><name sortKey="Laza Stanca, V" uniqKey="Laza Stanca V">V Laza-Stanca</name>
</author>
<author><name sortKey="Coyle, Aj" uniqKey="Coyle A">AJ Coyle</name>
</author>
<author><name sortKey="Papi, A" uniqKey="Papi A">A Papi</name>
</author>
<author><name sortKey="Johnston, Sl" uniqKey="Johnston S">SL Johnston</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nazzal, D" uniqKey="Nazzal D">D Nazzal</name>
</author>
<author><name sortKey="Gradolatto, A" uniqKey="Gradolatto A">A Gradolatto</name>
</author>
<author><name sortKey="Truffault, F" uniqKey="Truffault F">F Truffault</name>
</author>
<author><name sortKey="Bismuth, J" uniqKey="Bismuth J">J Bismuth</name>
</author>
<author><name sortKey="Berrih Aknin, S" uniqKey="Berrih Aknin S">S Berrih-Aknin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Qian, X" uniqKey="Qian X">X Qian</name>
</author>
<author><name sortKey="Agematsu, K" uniqKey="Agematsu K">K Agematsu</name>
</author>
<author><name sortKey="Freeman, Gj" uniqKey="Freeman G">GJ Freeman</name>
</author>
<author><name sortKey="Tagawa, Y" uniqKey="Tagawa Y">Y Tagawa</name>
</author>
<author><name sortKey="Sugane, K" uniqKey="Sugane K">K Sugane</name>
</author>
<author><name sortKey="Hayashi, T" uniqKey="Hayashi T">T Hayashi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kajiwara, K" uniqKey="Kajiwara K">K Kajiwara</name>
</author>
<author><name sortKey="Morishima, H" uniqKey="Morishima H">H Morishima</name>
</author>
<author><name sortKey="Akiyama, K" uniqKey="Akiyama K">K Akiyama</name>
</author>
<author><name sortKey="Yanagihara, Y" uniqKey="Yanagihara Y">Y Yanagihara</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kuroki, Y" uniqKey="Kuroki Y">Y Kuroki</name>
</author>
<author><name sortKey="Takahashi, M" uniqKey="Takahashi M">M Takahashi</name>
</author>
<author><name sortKey="Nishitani, C" uniqKey="Nishitani C">C Nishitani</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hu, Dd" uniqKey="Hu D">DD Hu</name>
</author>
<author><name sortKey="Mai, Jn" uniqKey="Mai J">JN Mai</name>
</author>
<author><name sortKey="He, Ly" uniqKey="He L">LY He</name>
</author>
<author><name sortKey="Li, Pq" uniqKey="Li P">PQ Li</name>
</author>
<author><name sortKey="Chen, Wx" uniqKey="Chen W">WX Chen</name>
</author>
<author><name sortKey="Yan, Jj" uniqKey="Yan J">JJ Yan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lee, Jj" uniqKey="Lee J">JJ Lee</name>
</author>
<author><name sortKey="Seah, Jb" uniqKey="Seah J">JB Seah</name>
</author>
<author><name sortKey="Chow, Vt" uniqKey="Chow V">VT Chow</name>
</author>
<author><name sortKey="Poh, Cl" uniqKey="Poh C">CL Poh</name>
</author>
<author><name sortKey="Tan, El" uniqKey="Tan E">EL Tan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Roth, M" uniqKey="Roth M">M Roth</name>
</author>
<author><name sortKey="Pasquali, C" uniqKey="Pasquali C">C Pasquali</name>
</author>
<author><name sortKey="Stolz, D" uniqKey="Stolz D">D Stolz</name>
</author>
<author><name sortKey="Tamm, M" uniqKey="Tamm M">M Tamm</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Witte, K" uniqKey="Witte K">K Witte</name>
</author>
<author><name sortKey="Koch, E" uniqKey="Koch E">E Koch</name>
</author>
<author><name sortKey="Volk, Hd" uniqKey="Volk H">HD Volk</name>
</author>
<author><name sortKey="Wolk, K" uniqKey="Wolk K">K Wolk</name>
</author>
<author><name sortKey="Sabat, R" uniqKey="Sabat R">R Sabat</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wilson, Ss" uniqKey="Wilson S">SS Wilson</name>
</author>
<author><name sortKey="Wiens, Me" uniqKey="Wiens M">ME Wiens</name>
</author>
<author><name sortKey="Smith, Jg" uniqKey="Smith J">JG Smith</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Guani Guerra, E" uniqKey="Guani Guerra E">E Guaní-Guerra</name>
</author>
<author><name sortKey="Negrete Garcia, Mc" uniqKey="Negrete Garcia M">MC Negrete-García</name>
</author>
<author><name sortKey="Montes Vizuet, R" uniqKey="Montes Vizuet R">R Montes-Vizuet</name>
</author>
<author><name sortKey="Asbun Bojalil, J" uniqKey="Asbun Bojalil J">J Asbun-Bojalil</name>
</author>
<author><name sortKey="Teran, Lm" uniqKey="Teran L">LM Terán</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Andresen, E" uniqKey="Andresen E">E Andresen</name>
</author>
<author><name sortKey="Gunther, G" uniqKey="Gunther G">G Günther</name>
</author>
<author><name sortKey="Bullwinkel, J" uniqKey="Bullwinkel J">J Bullwinkel</name>
</author>
<author><name sortKey="Lange, C" uniqKey="Lange C">C Lange</name>
</author>
<author><name sortKey="Heine, H" uniqKey="Heine H">H Heine</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Liao, Jy" uniqKey="Liao J">JY Liao</name>
</author>
<author><name sortKey="Zhang, T" uniqKey="Zhang T">T Zhang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bedke, N" uniqKey="Bedke N">N Bedke</name>
</author>
<author><name sortKey="Sammut, D" uniqKey="Sammut D">D Sammut</name>
</author>
<author><name sortKey="Green, B" uniqKey="Green B">B Green</name>
</author>
<author><name sortKey="Kehagia, V" uniqKey="Kehagia V">V Kehagia</name>
</author>
<author><name sortKey="Dennison, P" uniqKey="Dennison P">P Dennison</name>
</author>
<author><name sortKey="Jenkins, G" uniqKey="Jenkins G">G Jenkins</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gielen, V" uniqKey="Gielen V">V Gielen</name>
</author>
<author><name sortKey="Sykes, A" uniqKey="Sykes A">A Sykes</name>
</author>
<author><name sortKey="Zhu, J" uniqKey="Zhu J">J Zhu</name>
</author>
<author><name sortKey="Chan, B" uniqKey="Chan B">B Chan</name>
</author>
<author><name sortKey="Macintyre, J" uniqKey="Macintyre J">J Macintyre</name>
</author>
<author><name sortKey="Regamey, N" uniqKey="Regamey N">N Regamey</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wickert, Le" uniqKey="Wickert L">LE Wickert</name>
</author>
<author><name sortKey="Karta, Mr" uniqKey="Karta M">MR Karta</name>
</author>
<author><name sortKey="Audhya, A" uniqKey="Audhya A">A Audhya</name>
</author>
<author><name sortKey="Gern, Je" uniqKey="Gern J">JE Gern</name>
</author>
<author><name sortKey="Bertics, Pj" uniqKey="Bertics P">PJ Bertics</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hostettler, Ke" uniqKey="Hostettler K">KE Hostettler</name>
</author>
<author><name sortKey="Roth, M" uniqKey="Roth M">M Roth</name>
</author>
<author><name sortKey="Burgess, Jk" uniqKey="Burgess J">JK Burgess</name>
</author>
<author><name sortKey="Gencay, Mm" uniqKey="Gencay M">MM Gencay</name>
</author>
<author><name sortKey="Gambazzi, F" uniqKey="Gambazzi F">F Gambazzi</name>
</author>
<author><name sortKey="Black, Jl" uniqKey="Black J">JL Black</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Oliver, Bg" uniqKey="Oliver B">BG Oliver</name>
</author>
<author><name sortKey="Lim, S" uniqKey="Lim S">S Lim</name>
</author>
<author><name sortKey="Wark, P" uniqKey="Wark P">P Wark</name>
</author>
<author><name sortKey="Laza Stanca, V" uniqKey="Laza Stanca V">V Laza-Stanca</name>
</author>
<author><name sortKey="King, N" uniqKey="King N">N King</name>
</author>
<author><name sortKey="Black, Jl" uniqKey="Black J">JL Black</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kamin, W" uniqKey="Kamin W">W Kamin</name>
</author>
<author><name sortKey="Funk, P" uniqKey="Funk P">P Funk</name>
</author>
<author><name sortKey="Seifert, G" uniqKey="Seifert G">G Seifert</name>
</author>
<author><name sortKey="Zimmermann, A" uniqKey="Zimmermann A">A Zimmermann</name>
</author>
<author><name sortKey="Lehmacher, W" uniqKey="Lehmacher W">W Lehmacher</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lambers, C" uniqKey="Lambers C">C Lambers</name>
</author>
<author><name sortKey="Qi, Y" uniqKey="Qi Y">Y Qi</name>
</author>
<author><name sortKey="Eleni, P" uniqKey="Eleni P">P Eleni</name>
</author>
<author><name sortKey="Costa, L" uniqKey="Costa L">L Costa</name>
</author>
<author><name sortKey="Zhong, J" uniqKey="Zhong J">J Zhong</name>
</author>
<author><name sortKey="Tamm, M" uniqKey="Tamm M">M Tamm</name>
</author>
<author><name sortKey="Block, Lh" uniqKey="Block L">LH Block</name>
</author>
<author><name sortKey="Roth, M" uniqKey="Roth M">M Roth</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Matthys, H" uniqKey="Matthys H">H Matthys</name>
</author>
<author><name sortKey="Pliskevich, Da" uniqKey="Pliskevich D">DA Pliskevich</name>
</author>
<author><name sortKey="Bondarchuk, Om" uniqKey="Bondarchuk O">OM Bondarchuk</name>
</author>
<author><name sortKey="Malek, Fa" uniqKey="Malek F">FA Malek</name>
</author>
<author><name sortKey="Tribanek, M" uniqKey="Tribanek M">M Tribanek</name>
</author>
<author><name sortKey="Kieser, M" uniqKey="Kieser M">M Kieser</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Humphreys, Ir" uniqKey="Humphreys I">IR Humphreys</name>
</author>
<author><name sortKey="Edwards, L" uniqKey="Edwards L">L Edwards</name>
</author>
<author><name sortKey="Snelgrove, Rj" uniqKey="Snelgrove R">RJ Snelgrove</name>
</author>
<author><name sortKey="Rae, Aj" uniqKey="Rae A">AJ Rae</name>
</author>
<author><name sortKey="Coyle, Aj" uniqKey="Coyle A">AJ Coyle</name>
</author>
<author><name sortKey="Hussell, T" uniqKey="Hussell T">T Hussell</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wu, J" uniqKey="Wu J">J Wu</name>
</author>
<author><name sortKey="Cui, D" uniqKey="Cui D">D Cui</name>
</author>
<author><name sortKey="Yang, X" uniqKey="Yang X">X Yang</name>
</author>
<author><name sortKey="Lou, J" uniqKey="Lou J">J Lou</name>
</author>
<author><name sortKey="Lin, J" uniqKey="Lin J">J Lin</name>
</author>
<author><name sortKey="Ye, X" uniqKey="Ye X">X Ye</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="De Haij, S" uniqKey="De Haij S">S de Haij</name>
</author>
<author><name sortKey="Woltman, Am" uniqKey="Woltman A">AM Woltman</name>
</author>
<author><name sortKey="Trouw, La" uniqKey="Trouw L">LA Trouw</name>
</author>
<author><name sortKey="Bakker, Ac" uniqKey="Bakker A">AC Bakker</name>
</author>
<author><name sortKey="Kamerling, Sw" uniqKey="Kamerling S">SW Kamerling</name>
</author>
<author><name sortKey="Van Der Kooij, Sw" uniqKey="Van Der Kooij S">SW van der Kooij</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Macaubas, C" uniqKey="Macaubas C">C Macaubas</name>
</author>
<author><name sortKey="Dekruyff, Rh" uniqKey="Dekruyff R">RH DeKruyff</name>
</author>
<author><name sortKey="Umetsu, Dt" uniqKey="Umetsu D">DT Umetsu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Liu, W" uniqKey="Liu W">W Liu</name>
</author>
<author><name sortKey="Feng, W" uniqKey="Feng W">W Feng</name>
</author>
<author><name sortKey="Wang, F" uniqKey="Wang F">F Wang</name>
</author>
<author><name sortKey="Li, W" uniqKey="Li W">W Li</name>
</author>
<author><name sortKey="Zhou, B" uniqKey="Zhou B">B Zhou</name>
</author>
<author><name sortKey="Gao, C" uniqKey="Gao C">C Gao</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sato, J" uniqKey="Sato J">J Sato</name>
</author>
<author><name sortKey="Konno, N" uniqKey="Konno N">N Konno</name>
</author>
<author><name sortKey="Murakami, M" uniqKey="Murakami M">M Murakami</name>
</author>
<author><name sortKey="Uede, T" uniqKey="Uede T">T Uede</name>
</author>
<author><name sortKey="Himi, T" uniqKey="Himi T">T Himi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Blumer, T" uniqKey="Blumer T">T Blumer</name>
</author>
<author><name sortKey="Coto Llerena, M" uniqKey="Coto Llerena M">M Coto-Llerena</name>
</author>
<author><name sortKey="Duong, Fht" uniqKey="Duong F">FHT Duong</name>
</author>
<author><name sortKey="Heim, Mh" uniqKey="Heim M">MH Heim</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Dowran, R" uniqKey="Dowran R">R Dowran</name>
</author>
<author><name sortKey="Sarvari, J" uniqKey="Sarvari J">J Sarvari</name>
</author>
<author><name sortKey="Moattari, A" uniqKey="Moattari A">A Moattari</name>
</author>
<author><name sortKey="Fattahi, Mr" uniqKey="Fattahi M">MR Fattahi</name>
</author>
<author><name sortKey="Ramezani, A" uniqKey="Ramezani A">A Ramezani</name>
</author>
<author><name sortKey="Hosseini, Sy" uniqKey="Hosseini S">SY Hosseini</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Obajemu, Aa" uniqKey="Obajemu A">AA Obajemu</name>
</author>
<author><name sortKey="Rao, N" uniqKey="Rao N">N Rao</name>
</author>
<author><name sortKey="Dilley, Ka" uniqKey="Dilley K">KA Dilley</name>
</author>
<author><name sortKey="Vargas, Jm" uniqKey="Vargas J">JM Vargas</name>
</author>
<author><name sortKey="Sheikh, F" uniqKey="Sheikh F">F Sheikh</name>
</author>
<author><name sortKey="Donnelly, Rp" uniqKey="Donnelly R">RP Donnelly</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zhang, G" uniqKey="Zhang G">G. Zhang</name>
</author>
<author><name sortKey="Sunkara, L T" uniqKey="Sunkara L">L.T. Sunkara</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kalenik, Bm" uniqKey="Kalenik B">BM Kalenik</name>
</author>
<author><name sortKey="G Ra Sochacka, A" uniqKey="G Ra Sochacka A">A Góra-Sochacka</name>
</author>
<author><name sortKey="Sirko, A" uniqKey="Sirko A">A Sirko</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Careddu, D" uniqKey="Careddu D">D Careddu</name>
</author>
<author><name sortKey="Pettenazzo, A" uniqKey="Pettenazzo A">A Pettenazzo</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV2/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000D74 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 000D74 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= CovidV2 |flux= Main |étape= Merge |type= RBID |clé= PMC:6358071 |texte= Pelargonium sidoides radix extract EPs 7630 reduces rhinovirus infection through modulation of viral binding proteins on human bronchial epithelial cells }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Merge/RBID.i -Sk "pubmed:30707726" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Merge/biblio.hfd \ | NlmPubMed2Wicri -a CovidV2
![]() | This area was generated with Dilib version V0.6.33. | ![]() |