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2019 novel coronavirus patients' clinical characteristics, discharge rate, and fatality rate of meta-analysis.

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2019 novel coronavirus patients' clinical characteristics, discharge rate, and fatality rate of meta-analysis.

Auteurs : Long-Quan Li [République populaire de Chine] ; Tian Huang [République populaire de Chine] ; Yong-Qing Wang [République populaire de Chine] ; Zheng-Ping Wang [République populaire de Chine] ; Yuan Liang [République populaire de Chine] ; Tao-Bi Huang [République populaire de Chine] ; Hui-Yun Zhang [République populaire de Chine] ; Weiming Sun [République populaire de Chine] ; Yuping Wang [République populaire de Chine]

Source :

Journal of medical virology [ 1096-9071 ] ; 2020.

RBID : pubmed:32162702

Abstract

The aim of this study was to analyze the clinical data, discharge rate, and fatality rate of COVID-19 patients for clinical help. The clinical data of COVID-19 patients from December 2019 to February 2020 were retrieved from four databases. We statistically analyzed the clinical symptoms and laboratory results of COVID-19 patients and explained the discharge rate and fatality rate with a single-arm meta-analysis. The available data of 1994 patients in 10 literatures were included in our study. The main clinical symptoms of COVID-19 patients were fever (88.5%), cough (68.6%), myalgia or fatigue (35.8%), expectoration (28.2%), and dyspnea (21.9%). Minor symptoms include headache or dizziness (12.1%), diarrhea (4.8%), nausea and vomiting (3.9%). The results of the laboratory showed that the lymphocytopenia (64.5%), increase of C-reactive protein (44.3%), increase of lactic dehydrogenase (28.3%), and leukocytopenia (29.4%) were more common. The results of single-arm meta-analysis showed that the male took a larger percentage in the gender distribution of COVID-19 patients 60% (95% CI [0.54, 0.65]), the discharge rate of COVID-19 patients was 42% (95% CI [0.29, 0.55]), and the fatality rate was 7% (95% CI [0.04,0.10]).

DOI: 10.1002/jmv.25757
PubMed: 32162702

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Le document en format XML

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<front><div type="abstract" xml:lang="en">The aim of this study was to analyze the clinical data, discharge rate, and fatality rate of COVID-19 patients for clinical help. The clinical data of COVID-19 patients from December 2019 to February 2020 were retrieved from four databases. We statistically analyzed the clinical symptoms and laboratory results of COVID-19 patients and explained the discharge rate and fatality rate with a single-arm meta-analysis. The available data of 1994 patients in 10 literatures were included in our study. The main clinical symptoms of COVID-19 patients were fever (88.5%), cough (68.6%), myalgia or fatigue (35.8%), expectoration (28.2%), and dyspnea (21.9%). Minor symptoms include headache or dizziness (12.1%), diarrhea (4.8%), nausea and vomiting (3.9%). The results of the laboratory showed that the lymphocytopenia (64.5%), increase of C-reactive protein (44.3%), increase of lactic dehydrogenase (28.3%), and leukocytopenia (29.4%) were more common. The results of single-arm meta-analysis showed that the male took a larger percentage in the gender distribution of COVID-19 patients 60% (95% CI [0.54, 0.65]), the discharge rate of COVID-19 patients was 42% (95% CI [0.29, 0.55]), and the fatality rate was 7% (95% CI [0.04,0.10]).</div>
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2019 novel coronavirus patients' clinical characteristics, discharge rate, and fatality rate of meta-analysis.

2019 novel coronavirus patients' clinical characteristics, discharge rate, and fatality rate of meta-analysis.

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Abstract

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